Implementation of Kernelized score functions and other semi-supervised learning algorithms for node label ranking to analyze biomolecular networks. RANKS can be easily applied to a large set of different relevant problems in computational biology, ranging from automatic protein function prediction, to gene disease prioritization and drug repositioning, and more in general to any bioinformatics problem that can be formalized as a node label ranking problem in a graph. The modular nature of the implementation allows to experiment with different score functions and kernels and to easily compare the results with baseline network-based methods such as label propagation and random walk algorithms, as well as to enlarge the algorithmic scheme by adding novel user-defined score functions and kernels.

Get text from images of text using Captricity Optical Character Recognition (OCR) API. Captricity allows you to get text from handwritten forms --- think surveys --- and other structured paper documents. And it can output data in form a delimited file keeping field information intact. For more information, read <https://shreddr.captricity.com/developer/overview/>.

Eases the use of ecotoxicological effect models. Can simulate common toxicokinetic-toxicodynamic (TK/TD) models such as General Unified Threshold models of Survival (GUTS) and Lemna. It can derive effects and effect profiles (EPx) from scenarios. It supports the use of tidyr workflows employing the pipe symbol. Time-consuming tasks can be parallelized.

This package provides a fast and general implementation of the Elston-Stewart algorithm that can calculate the likelihoods of large and complex pedigrees. References for the Elston-Stewart algorithm are Elston & Stewart (1971) <doi:10.1159/000152448>, Lange & Elston (1975) <doi:10.1159/000152714> and Cannings et al. (1978) <doi:10.2307/1426718>.

We provide the main R functions to compute the posterior interval for the noncentrality parameter of the chi-squared distribution. The skewness estimate of the posterior distribution is also available to improve the coverage rate of posterior intervals. Details can be found in Du and Hu (2020) <doi:10.1080/01621459.2020.1777137>.

This package provides a neighborhood-based, greedy search algorithm is performed to estimate a feature allocation by minimizing the expected loss based on posterior samples from the feature allocation distribution. The method is described in Dahl, Johnson, and Andros (2023) "Comparison and Bayesian Estimation of Feature Allocations" <doi:10.1080/10618600.2023.2204136>.

Given a postulated model and a set of data, the comparison density is estimated and the deviance test is implemented in order to assess if the data distribution deviates significantly from the postulated model. Finally, the results are summarized in a CD-plot as described in Algeri S. (2019) <arXiv:1906.06615>.

Generate concentration-time profiles from linear pharmacokinetic (PK) systems, possibly with first-order absorption or zero-order infusion, possibly with one or more peripheral compartments, and possibly under steady-state conditions. Single or multiple doses may be specified. Secondary (derived) PK parameters (e.g. Cmax, Ctrough, AUC, Tmax, half-life, etc.) are computed.

Compose generic monadic function pipelines with %>>% and %>-% based on implementing the S7 generics fmap() and bind(). Methods are provided for the built-in list type and the maybe class from the maybe package. The concepts are modelled directly after the Monad typeclass in Haskell, but adapted for idiomatic use in R.

Automates and standardizes the import of raw data from Oregon RFID (radio-frequency identification) ORMR (Oregon RFID Multi-Reader) and ORSR (Oregon RFID Single Reader) antenna readers. Compiled data can then be combined within multi-reader arrays for further analysis, including summarizing tag and reader detections, determining tag direction, and calculating antenna efficiency.

This package implements a simulation study to assess the strengths and weaknesses of causal inference methods for estimating policy effects using panel data. See Griffin et al. (2021) <doi:10.1007/s10742-022-00284-w> and Griffin et al. (2022) <doi:10.1186/s12874-021-01471-y> for a description of our methods.

Quantile regression with fixed effects is a general model for longitudinal data. Here we proposed to solve it by several methods. The estimation methods include three loss functions as check, asymmetric least square and asymmetric Huber functions; and three structures as simple regression, fixed effects and fixed effects with penalized intercepts by LASSO.

Allows the user to connect with the World Spider Catalogue (WSC; <https://wsc.nmbe.ch/>) and the World Spider Trait (WST; <https://spidertraits.sci.muni.cz/>) databases. Also performs several basic functions such as checking names validity, retrieving coordinate data from the Global Biodiversity Information Facility (GBIF; <https://www.gbif.org/>), and mapping.

This package provides routines to check identifiability or non-identifiability of linear structural equation models as described in Drton, Foygel, and Sullivant (2011) <doi:10.1214/10-AOS859>, Foygel, Draisma, and Drton (2012) <doi:10.1214/12-AOS1012>, and other works. The routines are based on the graphical representation of structural equation models.

This package provides a method to explore the treatment-covariate interactions in survival or generalized linear model (GLM) for continuous, binomial and count data arising from two or more treatment arms of a clinical trial. A permutation distribution approach to inference is implemented, based on permuting the covariate values within each treatment group.

Likelihood ratio and maximum likelihood statistics are provided that can be used as alternatives to p-values Colquhoun (2017) <doi:10.1098/rsos.171085>. Arguments can be either p-values or t-statistics. together with degrees of freedom. For the function tTOlr', the argument twoSided has the default twoSided = TRUE'.

Obtain United States map data frames of varying region types (e.g. county, state). The map data frames include Alaska and Hawaii conveniently placed to the bottom left, as they appear in most maps of the US. Convenience functions for plotting choropleths, visualizing spatial data, and working with FIPS codes are also provided.

Supplies permutation-test alternatives to traditional hypothesis-test procedures such as two-sample tests for means, medians, and standard deviations; correlation tests; tests for homogeneity and independence; and more. Suitable for general audiences, including individual and group users, introductory statistics courses, and more advanced statistics courses that desire an introduction to permutation tests.

Nonparametric estimation of discount functions and yield curves from transaction data of coupon paying bonds. Koo, B., La Vecchia, D., & Linton, O. B. (2021) <doi:10.1016/j.jeconom.2020.04.014> describe an application of this package using the Center for Research in Security Prices (CRSP) Bond Data and document its implementation.

performing all the steps of gene expression meta-analysis considering the possible existence of missing genes. It provides the necessary functions to be able to perform the different methods of gene expression meta-analysis. In addition, it contains functions to apply quality controls, download GEO datasets and show graphical representations of the results.

This package provides a package for gene set analysis based on the variability of expressions as well as a method to detect Alternative Splicing Events . It implements DIfferential RAnk Conservation (DIRAC) and gene set Expression Variation Analysis (EVA) methods. For detecting Differentially Spliced genes, it provides an implementation of the Spliced-EVA (SEVA).

Redkite is a small GUI toolkit developed in C++17 and inspired from other well known GUI toolkits such as Qt and GTK. It is minimal on purpose and is intended to be statically linked to applications, therefore satisfying any requirements they may have to be self contained, as is the case with audio plugins.

The canonical way to perform meta-analysis involves using effect sizes. When they are not available this package provides a number of methods for meta-analysis of significance values including the methods of Edgington, Fisher, Stouffer, Tippett, and Wilkinson; a number of data-sets to replicate published results; and a routine for graphical display.

This package provides functions necessary to perform Weighted Correlation Network Analysis on high-dimensional data. It includes functions for rudimentary data cleaning, construction and summarization of correlation networks, module identification and functions for relating both variables and modules to sample traits. It also includes a number of utility functions for data manipulation and visualization.