Create fake datasets that can be used for prototyping and teaching. This package provides a set of functions to generate fake data for a variety of data types, such as dates, addresses, and names. It can be used for prototyping (notably in shiny') or as a tool to teach data manipulation and data visualization.

This package provides a wrapper for the python module FIORA as well as a shiny'-App to facilitate data processing and visualization. FIORA allows to predict Mass-Spectra based on the SMILES code of chemical compounds. It is described in the Nature Communications article by Nowatzky (2025) <doi:10.1038/s41467-025-57422-4>.

We propose the inverse probability-of-censoring weighted (IPCW) Kendall's tau to measure the association of the survival trait with biomarkers and Kendall's partial correlation to reflect the relationship of the survival trait with interaction variable conditional on main effects, as described in Wang and Chen (2020) <doi:10.1093/bioinformatics/btaa017>.

This package provides a set of functions to compute the Hodrick-Prescott (HP) filter with automatically selected jumps. The original HP filter extracts a smooth trend from a time series, and our version allows for a small number of automatically identified jumps. See Maranzano and Pelagatti (2024) <doi:10.2139/ssrn.4896170> for details.

This package provides a GUI interface for automating data extraction from multiple images containing scatter and bar plots, semi-automated tools to tinker with extraction attempts, and a fully-loaded point-and-click manual extractor with image zoom, calibrator, and classifier. Also provides detailed and R-independent extraction reports as fully-embedded .html records.

This package implements the LS-PLS (least squares - partial least squares) method described in for instance Jørgensen, K., Segtnan, V. H., Thyholt, K., Næs, T. (2004) "A Comparison of Methods for Analysing Regression Models with Both Spectral and Designed Variables" Journal of Chemometrics, 18(10), 451--464, <doi:10.1002/cem.890>.

This package provides a variety of models to analyze latent variables based on Bayesian learning: the partially CFA (Chen, Guo, Zhang, & Pan, 2020) <DOI: 10.1037/met0000293>; generalized PCFA; partially confirmatory IRM (Chen, 2020) <DOI: 10.1007/s11336-020-09724-3>; Bayesian regularized EFA <DOI: 10.1080/10705511.2020.1854763>; Fully and partially EFA.

Classify missing data as missing completely at random (MCAR), missing at random (MAR), or missing not at random (MNAR). This step is required before handling missing data (e.g. mean imputation) so that bias is not introduced. See Little (1988) <doi:10.1080/01621459.1988.10478722> for the statistical rationale for the methods used.

Post-selection inference in linear regression models, constructing simultaneous confidence intervals across a user-specified universe of models. Implements the methodology described in Kuchibhotla, Kolassa, and Kuffner (2022) "Post-Selection Inference" <doi:10.1146/annurev-statistics-100421-044639> to ensure valid inference after model selection, with applications in high-dimensional settings like Lasso selection.

Robust penalized (adaptive) elastic net S and M estimators for linear regression. The methods are proposed in Cohen Freue, G. V., Kepplinger, D., Salibián-Barrera, M., and Smucler, E. (2019) <https://projecteuclid.org/euclid.aoas/1574910036>. The package implements the extensions and algorithms described in Kepplinger, D. (2020) <doi:10.14288/1.0392915>.

Quantile regression (QR) for Linear Mixed-Effects Models via the asymmetric Laplace distribution (ALD). It uses the Stochastic Approximation of the EM (SAEM) algorithm for deriving exact maximum likelihood estimates and full inference results for the fixed-effects and variance components. It also provides graphical summaries for assessing the algorithm convergence and fitting results.

This package implements statistical methods for analyzing the counts of areal data, with a focus on the detection of spatial clusters and clustering. The package has a heavy emphasis on spatial scan methods, which were first introduced by Kulldorff and Nagarwalla (1995) <doi:10.1002/sim.4780140809> and Kulldorff (1997) <doi:10.1080/03610929708831995>.

This package implements tipping point sensitivity analysis for time-to-event endpoints under different missing data scenarios, as described in Oodally et al. (2025) <doi:10.48550/arXiv.2506.19988>. Supports both model-based and model-free imputation, multiple imputation workflows, plausibility assessment and visualizations. Enables robust assessment for regulatory and exploratory analyses.

The best way to implement middle ware for shiny Applications. tower is designed to make implementing behavior on top of shiny easy with a layering model for incoming HTTP requests and server sessions. tower is a very minimal package with little overhead, it is mainly meant for other package developers to implement new behavior.

Estimation methods for zero-inflated Poisson factor analysis (ZIPFA) on sparse data. It provides estimates of coefficients in a new type of zero-inflated regression. It provides a cross-validation method to determine the potential rank of the data in the ZIPFA and conducts zero-inflated Poisson factor analysis based on the determined rank.

This R package is for multi-sample transcript discovery and quantification using long read RNA-Seq data. You can use bambu after read alignment to obtain expression estimates for known and novel transcripts and genes. The output from bambu can directly be used for visualisation and downstream analysis, such as differential gene expression or transcript usage.

This package provides methods for spatial data analysis, especially raster data. The included methods allow for low-level data manipulation as well as high-level global, local, zonal, and focal computation. The predict and interpolate methods facilitate the use of regression type (interpolation, machine learning) models for spatial prediction. Processing of very large files is supported.

This package implements a metabolic network analysis pipeline to identify an active metabolic module based on high throughput data. The pipeline takes as input transcriptional and/or metabolic data and finds a metabolic subnetwork (module) most regulated between the two conditions of interest. The package further provides functions for module post-processing, annotation and visualization.

This package provides a seamless interface to the MEME Suite family of tools for motif analysis. memes provides data aware utilities for using GRanges objects as entrypoints to motif analysis, data structures for examining & editing motif lists, and novel data visualizations. memes functions and data structures are amenable to both base R and tidyverse workflows.

This package implements a general purpose gene set analysis method called PADOG that downplays the importance of genes that apear often accross the sets of genes to be analyzed. The package provides also a benchmark for gene set analysis methods in terms of sensitivity and ranking using 24 public datasets from KEGGdzPathwaysGEO package.

The package offers statistical tests based on the 2-Wasserstein distance for detecting and characterizing differences between two distributions given in the form of samples. Functions for calculating the 2-Wasserstein distance and testing for differential distributions are provided, as well as a specifically tailored test for differential expression in single-cell RNA sequencing data.

This package performs estimation of marginal treatment effects for binary outcomes when using logistic regression working models with covariate adjustment (see discussions in Magirr et al (2024) <https://osf.io/9mp58/>). Implements the variance estimators of Ge et al (2011) <doi:10.1177/009286151104500409> and Ye et al (2023) <doi:10.1080/24754269.2023.2205802>.

Generate synthetic station-based monthly climate time-series including temperature and rainfall, export to Network Common Data Form (NetCDF), and provide visualization helpers for climate workflows. The approach is inspired by statistical weather generator concepts described in Wilks (1992) <doi:10.1016/S0168-1923(99)00037-4> and Richardson (1981) <doi:10.1029/WR017i001p00182>.

This package contains a large number of the goodness-of-fit tests for the Exponential and Weibull distributions classified into families: the tests based on the empirical distribution function, the tests based on the probability plot, the tests based on the normalized spacings, the tests based on the Laplace transform and the likelihood based tests.