Computes the ACMIF test and Bonferroni-adjusted p-value of interaction in two-factor studies. Produces corresponding interaction plot and analysis of variance tables and p-values from several other tests of non-additivity.

Provide functionality to manage, clean and match highfrequency trades and quotes data, calculate various liquidity measures, estimate and forecast volatility, detect price jumps and investigate microstructure noise and intraday periodicity. A detailed vignette can be found in the open-access paper "Analyzing Intraday Financial Data in R: The highfrequency Package" by Boudt, Kleen, and Sjoerup (2022, <doi:10.18637/jss.v104.i08>).

Simulates stochastic hybrid models for transmission of infectious diseases in dynamic networks. It is a metapopulation model in which each node in the network is a sub-population and disease spreads within nodes and among them, combining two approaches: stochastic simulation algorithm (<doi:10.1146/annurev.physchem.58.032806.104637>) and individual-based approach, respectively. Equations that models spread within nodes are customizable and there are two link types among nodes: migration and influence (commuting). More information in Fernando S. Marques, Jose H. H. Grisi-Filho, Marcos Amaku et al. (2020) <doi:10.18637/jss.v094.i06>.

This package implements the sample size methods for hierarchical 2x2 factorial trials under two choices of effect estimands and a series of hypothesis tests proposed in "Sample size calculation in hierarchical 2x2 factorial trials with unequal cluster sizes" (under review), and provides the table and plot generators for the sample size estimations.

This package provides a comprehensive R package for accessing and working with publicly available and free resources from the Agency for Healthcare Research and Quality (AHRQ) Healthcare Cost and Utilization Project (HCUP). The package provides streamlined access to HCUP's Clinical Classifications Software Refined (CCSR) mapping files and Summary Trend Tables, enabling researchers and analysts to efficiently map ICD-10-CM diagnosis codes and ICD-10-PCS procedure codes to CCSR categories and access HCUP statistical reports. Key features include: direct download from HCUP website, multiple output formats (long/wide/default), cross-classification support, version management, citation generation, and intelligent caching. The package does not redistribute HCUP data files but facilitates direct download from the official HCUP website, ensuring users always have access to the latest versions and maintain compliance with HCUP data use policies. This package only accesses free public tools and reports; it does NOT access HCUP databases (NIS, KID, SID, NEDS, etc.) that require purchase. For more information, see <https://hcup-us.ahrq.gov/>.

Construction and analysis of multivalued zero-sum matrix games over the abstract space of probability distributions, which describe the losses in each scenario of defense vs. attack action. The distributions can be compiled directly from expert opinions or other empirical data (insofar available). The package implements the methods put forth in the EU project HyRiM (Hybrid Risk Management for Utility Networks), FP7 EU Project Number 608090. The method has been published in Rass, S., König, S., Schauer, S., 2016. Decisions with Uncertain Consequences-A Total Ordering on Loss-Distributions. PLoS ONE 11, e0168583. <doi:10.1371/journal.pone.0168583>, and applied for advanced persistent thread modeling in Rass, S., König, S., Schauer, S., 2017. Defending Against Advanced Persistent Threats Using Game-Theory. PLoS ONE 12, e0168675. <doi:10.1371/journal.pone.0168675>. A volume covering the wider range of aspects of risk management, partially based on the theory implemented in the package is the book edited by S. Rass and S. Schauer, 2018. Game Theory for Security and Risk Management: From Theory to Practice. Springer, <doi:10.1007/978-3-319-75268-6>, ISBN 978-3-319-75267-9.

It provides three implementations of hash tables and hash maps: 1. using std::unordered_map and std::unordered_set C++ libraries, 2. wrapping around the fastmatch package, 3. using R environment.

Statistical analysis of static chamber concentration data for trace gas flux estimation.

This package provides a lightweight framework for creating high quality, complex heatmaps using base graphics. Supports hierarchical clustering with dendrograms, column and row scaling, cluster sub-divisions, customizable cell colours, shapes and sizes, legends, and flexible layouts for arranging multiple heatmaps. Designed to return plot objects that can be easily arranged with other plots without sacrificing resolution. Methods for hierarchical clustering and distance computations are described in Murtagh and Contreras (2012) <doi:10.1002/wics.53>. Dendrogram visualisation methods are based on the ggdendro package by de Vries and Ripley (2020) <https://CRAN.R-project.org/package=ggdendro>.

Generates HIDECAN plots that summarise and combine the results of genome-wide association studies (GWAS) and transcriptomics differential expression analyses (DE), along with manually curated candidate genes of interest. The HIDECAN plot is presented in Angelin-Bonnet et al. (2023) (currently in review).

An implementation for high-dimensional time series analysis methods, including factor model for vector time series proposed by Lam and Yao (2012) <doi:10.1214/12-AOS970> and Chang, Guo and Yao (2015) <doi:10.1016/j.jeconom.2015.03.024>, martingale difference test proposed by Chang, Jiang and Shao (2023) <doi:10.1016/j.jeconom.2022.09.001>, principal component analysis for vector time series proposed by Chang, Guo and Yao (2018) <doi:10.1214/17-AOS1613>, cointegration analysis proposed by Zhang, Robinson and Yao (2019) <doi:10.1080/01621459.2018.1458620>, unit root test proposed by Chang, Cheng and Yao (2022) <doi:10.1093/biomet/asab034>, white noise tests proposed by Chang, Yao and Zhou (2017) <doi:10.1093/biomet/asw066> and Chang et al. (2026+), CP-decomposition for matrix time series proposed by Chang et al. (2023) <doi:10.1093/jrsssb/qkac011> and Chang et al. (2026+) <doi:10.48550/arXiv.2410.05634>, CP-decomposition for tensor time series proposed by Chang et al. (2026+) <doi:10.48550/arXiv.2606.08560>, and statistical inference for spectral density matrix proposed by Chang et al. (2025) <doi:10.1080/01621459.2025.2468013>.

This package implements hierarchical Bayesian inference, robust frequentist inference, and distribution-free inference for dependent and unbalanced data under strong-mixing conditions. Supports triangular-array, weighted-sum and mixingale convergence regimes with Whittle and composite likelihoods, heteroskedasticity-and-autocorrelation-consistent variance estimation, block bootstrap with automatic block length, fixed-bandwidth HAR inference, adaptive conformal prediction, Bayesian decision under Region of Practical Equivalence, bridge-sampling Bayes factors, and predictive comparison via the Widely Applicable Information Criterion and leave-future-out cross-validation. Methods follow Andrews (1991) <doi:10.2307/2938229>, Kiefer and Vogelsang (2005) <doi:10.1017/S0266466605050565>, Patton, Politis and White (2009) <doi:10.1080/07474930802459016>, Vehtari, Gelman and Gabry (2017) <doi:10.1007/s11222-016-9696-4>, Kruschke (2018) <doi:10.1177/2515245918771304>, and Gibbs and Candes (2021) <doi:10.48550/arXiv.2106.00170>.

This package provides functions to calculate the Hotellingâ s T-squared statistic and corresponding confidence ellipses. Provides the semi-axes of the Hotellingâ s T-squared ellipses at 95% and 99% confidence levels. Enables users to obtain the coordinates in two or three dimensions at user-defined confidence levels, allowing for the construction of 2D or 3D ellipses with customized confidence levels. Bro and Smilde (2014) <DOI:10.1039/c3ay41907j>. Brereton (2016) <DOI:10.1002/cem.2763>.

Comfortable ways to work with hyperspectral data sets. I.e. spatially or time-resolved spectra, or spectra with any other kind of information associated with each of the spectra. The spectra can be data as obtained in XRF, UV/VIS, Fluorescence, AES, NIR, IR, Raman, NMR, MS, etc. More generally, any data that is recorded over a discretized variable, e.g. absorbance = f(wavelength), stored as a vector of absorbance values for discrete wavelengths is suitable.

For supersonic aircraft, flying subsonic over land, find the best route between airports. Allow for coastal buffer and potentially closed regions. Use a minimal model of aircraft performance: the focus is on time saved versus subsonic flight, rather than on vertical flight profile. For modelling and forecasting, not for planning your flight!

Published meta-analyses routinely present one of the measures of heterogeneity introduced in Higgins and Thompson (2002) <doi:10.1002/sim.1186>. For critiquing articles it is often better to convert to another of those measures. Some conversions are provided here and confidence intervals are also available.

Allows to evaluate Higher Order Assortativity of complex networks defined through objects of class igraph from the package of the same name. The package returns a result also for directed and weighted graphs. References, Arcagni, A., Grassi, R., Stefani, S., & Torriero, A. (2017) <doi:10.1016/j.ejor.2017.04.028> Arcagni, A., Grassi, R., Stefani, S., & Torriero, A. (2021) <doi:10.1016/j.jbusres.2019.10.008> Arcagni, A., Cerqueti, R., & Grassi, R. (2023) <doi:10.48550/arXiv.2304.01737>.

Estimate parameters of the hysteretic threshold autoregressive (HysTAR) model, using conditional least squares. In addition, you can generate time series data from the HysTAR model. For details, see Li, Guan, Li and Yu (2015) <doi:10.1093/biomet/asv017>.

This package implements the estimators and algorithms described in Chapters 8 and 9 of the book "The Fundamentals of Heavy Tails: Properties, Emergence, and Estimation" by Nair et al. (2022, ISBN:9781009053730). These include the Hill estimator, Moments estimator, Pickands estimator, Peaks-over-Threshold (POT) method, Power-law fit, and the Double Bootstrap algorithm.

Higher-order latent trait theory (item response theory). We implement the generalized partial credit model with a second-order latent trait structure. Latent regression can be done on the second-order latent trait. For a pre-print of the methods, see, "Latent Regression in Higher-Order Item Response Theory with the R Package hlt" <https://mkleinsa.github.io/doc/hlt_proof_draft_brmic.pdf>.

Automatically displays the order and spatial weighting matrix of the distance between locations. This concept was derived from the research of Mubarak, Aslanargun, and Siklar (2021) <doi:10.52403/ijrr.20211150> and Mubarak, Aslanargun, and Siklar (2022) <doi:10.17654/0972361722052>. Distance data between locations can be imported from Ms. Excel', maps package or created in R programming directly. This package also provides 5 simulations of distances between locations derived from fictitious data, the maps package, and from research by Mubarak, Aslanargun, and Siklar (2022) <doi:10.29244/ijsa.v6i1p90-100>.

Facilitates building topology preserving maps for data analysis.

Inference concerning equilibrium and random mating in autopolyploids. Methods are available to test for equilibrium and random mating at any even ploidy level (>2) in the presence of double reduction at biallelic loci. For autopolyploid populations in equilibrium, methods are available to estimate the degree of double reduction. We also provide functions to calculate genotype frequencies at equilibrium, or after one or several rounds of random mating, given rates of double reduction. The main function is hwefit(). This material is based upon work supported by the National Science Foundation under Grant No. 2132247. The opinions, findings, and conclusions or recommendations expressed are those of the author and do not necessarily reflect the views of the National Science Foundation. For details of these methods, see Gerard (2023a) <doi:10.1111/biom.13722> and Gerard (2023b) <doi:10.1111/1755-0998.13856>.

In some cases you will have data in a histogram format, where you have a vector of all possible observations, and a vector of how many times each observation appeared. You could expand this into a single 1D vector, but this may not be advisable if the counts are extremely large. HistDat allows for the calculation of summary statistics without the need for expanding your data.