This package builds on the Epimods framework which facilitates finding weighted subnetworks ("modules") on Illumina Infinium 27k arrays using the SpinGlass algorithm, as implemented in the iGraph package. We have created a class of gene centric annotations associated with p-values and effect sizes and scores from any researchers prior statistical results to find functional modules.

Enables simultaneous statistical inference for the accuracy of multiple classifiers in multiple subgroups (strata). For instance, allows to perform multiple comparisons in diagnostic accuracy studies with co-primary endpoints sensitivity and specificity (Westphal M, Zapf A. Statistical inference for diagnostic test accuracy studies with multiple comparisons. Statistical Methods in Medical Research. 2024;0(0). <doi:10.1177/09622802241236933>).

Extension of cmprsk to Stratified and Clustered data. A goodness of fit test for Fine-Gray model is also provided. Methods are detailed in the following articles: Zhou et al. (2011) <doi:10.1111/j.1541-0420.2010.01493.x>, Zhou et al. (2012) <doi:10.1093/biostatistics/kxr032>, Zhou et al. (2013) <doi: 10.1002/sim.5815>.

This package provides functions to facilitate access to the DKAN API (<https://dkan.readthedocs.io/en/latest/apis/index.html>), including the DKAN REST API (metadata), and the DKAN datastore API (data). Includes functions to list, create, retrieve, update, and delete datasets and resources nodes. It also includes functions to search and retrieve data from the DKAN datastore.

Piecewise linear segmentation of ordered data by a dynamic programming algorithm. The algorithm was developed for time series data, e.g. growth curves, and for genome-wide read-count data from next generation sequencing, but is broadly applicable. Generic implementations of dynamic programming routines allow to scan for optimal segmentation parameters and test custom segmentation criteria ("scoring functions").

Create list comprehensions (and other types of comprehension) similar to those in python', haskell', and other languages. List comprehension in R converts a regular for() loop into a vectorized lapply() function. Support for looping with multiple variables, parallelization, and across non-standard objects included. Package also contains a variety of functions to help with list comprehension.

This package provides functions to implement the Flexible cFDR (Hutchinson et al. (2021) <doi:10.1371/journal.pgen.1009853>) and Binary cFDR (Hutchinson et al. (2021) <doi:10.1101/2021.10.21.465274>) methodologies to leverage auxiliary data from arbitrary distributions, for example functional genomic data, with GWAS p-values to generate re-weighted p-values.

Upload, download, and edit internet maps with the Felt API (<https://developers.felt.com/rest-api/getting-started>). Allows users to create new maps, edit existing maps, and extract data. Provides tools for working with layers, which represent geographic data, and elements, which are interactive annotations. Spatial data accessed from the API is transformed to work with sf'.

Likelihood-free inference method for stochastic models. Uses a deterministic optimizer on simple simulations of the model that are performed with a prior drawn randomness by applying the inverse transform method. Is designed to work on its own and also by using the Julia package Jflimo available on the git page of the project: <https://metabarcoding.org/flimo>.

Solves goal programming problems of the weighted and lexicographic type, as well as combinations of the two, as described by Ignizio (1983) <doi:10.1016/0305-0548(83)90003-5>. Allows for a simple human-readable input describing the problem as a series of equations. Relies on the lpSolve package to solve the underlying linear optimisation problem.

Generalized Entropy Calibration produces calibration weights using generalized entropy as the objective function for optimization. This approach, as implemented in the GECal package, is based on Kwon, Kim, and Qiu (2024) <doi:10.48550/arXiv.2404.01076>. GECal incorporates design weights into the constraints to maintain design consistency, rather than including them in the objective function itself.

This package provides a function to retrieve the system timezone on Unix systems which has been found to find an answer when Sys.timezone() has failed. It is based on an answer by Duane McCully posted on StackOverflow', and adapted to be callable from R. The package also builds on Windows, but just returns NULL.

Estimates networks of conditional dependencies (Gaussian graphical models) from multiple classes of data (similar but not exactly, i.e. measurements on different equipment, in different locations or for various sub-types). Package also allows to generate simulation data and evaluate the performance. Implementation of the method described in Angelini, De Canditiis and Plaksienko (2022) <doi:10.3390/math10213983>.

Estimation of Latent Order Logistic (LOLOG) Models for Networks. LOLOGs are a flexible and fully general class of statistical graph models. This package provides functions for performing MOM, GMM and variational inference. Visual diagnostics and goodness of fit metrics are provided. See Fellows (2018) <doi:10.48550/arXiv.1804.04583> for a detailed description of the methods.

Random Forest Spatial Interpolation (RFSI, SekuliÄ et al. (2020) <doi:10.3390/rs12101687>) and spatio-temporal geostatistical (spatio-temporal regression Kriging (STRK)) interpolation for meteorological (Kilibarda et al. (2014) <doi:10.1002/2013JD020803>, SekuliÄ et al. (2020) <doi:10.1007/s00704-019-03077-3>) and other environmental variables. Contains global spatio-temporal models calculated using publicly available data.

Calculation of molecular number and brightness from fluorescence microscopy image series. The software was published in a 2016 paper <doi:10.1093/bioinformatics/btx434>. The seminal paper for the technique is Digman et al. 2008 <doi:10.1529/biophysj.107.114645>. A review of the technique was published in 2017 <doi:10.1016/j.ymeth.2017.12.001>.

It provides ensemble capabilities to supervised and unsupervised learning models predictions without using training labels. It decides the relative weights of the different models predictions by using best models predictions as response variable and rest of the mo. User can decide the best model, therefore, It provides freedom to user to ensemble models based on their design solutions.

Statistical methods for estimating preferential attachment and node fitness generative mechanisms in temporal complex networks are provided. Thong Pham et al. (2015) <doi:10.1371/journal.pone.0137796>. Thong Pham et al. (2016) <doi:10.1038/srep32558>. Thong Pham et al. (2020) <doi:10.18637/jss.v092.i03>. Thong Pham et al. (2021) <doi:10.1093/comnet/cnab024>.

Allows you to make clean, good-looking scatter plots with the option to easily add marginal density or box plots on the axes. It is also available as a module for jamovi (see <https://www.jamovi.org> for more information). Scatr is based on the cowplot package by Claus O. Wilke and the ggplot2 package by Hadley Wickham.

An implementation of Lind and Mehlum's (2010) <doi:10.1111/j.1468-0084.2009.00569.x> Utest to test for the presence of a U shaped or inverted U shaped relationship between variables in (generalized) linear models. It also implements a test of upward/downward sloping relationships at the lower and upper boundary of the data range.

Conducts linear regression using variational Bayesian inference, particularly optimized for genome-wide association mapping and whole-genome prediction which use a number of DNA markers as the explanatory variables. Provides seven regression models which select the important variables (i.e., the variables related to response variables) among the given explanatory variables in different ways (i.e., model structures).

Computes inequality measures of a given variable taking into account weights. Suitable for ratio, interval and ordered scale. Includes Gini, Theil, Leti index, Palma ratio, 20:20 ratio, Allison and Foster index, Jenkins index, Cowell and Flechaire index, Abul Naga and Yalcin index, Apouey index, Blair and Lacy index. Bootstrap provides distribution of inequality measures enabling significance tests.

The formr R package provides a few convenience functions that may be useful to the users of formr (formr.org), an online survey framework which heavily relies on R via openCPU. Some of the functions are for conveniently generating individual feedback graphics, some are just shorthands to make certain common operations in formr more palatable to R novices.

This package provides several cubic spline interpolation methods of H. Akima for irregular and regular gridded data are available through this package, both for the bivariate case and univariate case. Linear interpolation of irregular gridded data is also covered. A bilinear interpolator for regular grids was also added for comparison with the bicubic interpolator on regular grids.