Collection of indices and tools relating to clinical research that aid epidemiological cohort or retrospective chart review with big data. All indices and tools take commonly used lab values, patient demographics, and clinical measurements to compute various risk and predictive values for survival or further classification/stratification. References to original literature and validation contained in each function documentation. Includes all commonly available calculators available online.

This package provides a dimension reduction technique for outlier detection. DOBIN: a Distance based Outlier BasIs using Neighbours, constructs a set of basis vectors for outlier detection. This is not an outlier detection method; rather it is a pre-processing method for outlier detection. It brings outliers to the fore-front using fewer basis vectors (Kandanaarachchi, Hyndman 2020) <doi:10.1080/10618600.2020.1807353>.

Extract features from tabular data in a declarative fashion, with a focus on processing medical records. Features are specified as JSON and are independently processed before being joined. Input data can be provided as CSV files or as data frames. This setup ensures that data is transformed in a modular and reproducible manner, and allows the same pipeline to be easily applied to new data.

Implementation of an Event Categorization Matrix (ECM) detonation detection model and a Bayesian variant. Functions are provided for importing and exporting data, fitting models, and applying decision criteria for categorizing new events. This package implements methods described in the paper "Bayesian Event Categorization Matrix Approach for Nuclear Detonations" Koermer, Carmichael, and Williams (2024) available on arXiv at <doi:10.48550/arXiv.2409.18227>.

The Occluded Surface (OS) algorithm is a widely used approach for analyzing atomic packing in biomolecules as described by Pattabiraman N, Ward KB, Fleming PJ (1995) <doi:10.1002/jmr.300080603>. Here, we introduce fibos', an R and Python package that extends the OS methodology, as presented in Soares HHM, Romanelli JPR, Fleming PJ, da Silveira CH (2024) <doi:10.1101/2024.11.01.621530>.

Easy way to plot regular/weighted/conditional distributions by using formulas. The core of the package concerns distribution plots which are automatic: the many options are tailored to the data at hand to offer the nicest and most meaningful graphs possible -- with no/minimum user input. Further provide functions to plot conditional trends and box plots. See <https://lrberge.github.io/fplot/> for more information.

Forest Many-Objective Robust Decision Making ('FoRDM') is a R toolkit for supporting robust forest management under deep uncertainty. It provides a forestry-focused application of Many-Objective Robust Decision Making ('MORDM') to forest simulation outputs, enabling users to evaluate robustness using regret- and satisficing'-based measures. FoRDM identifies robust solutions, generates Pareto fronts, and offers interactive 2D, 3D, and parallel-coordinate visualizations.

This package provides a framework and functions to create MOODLE quizzes. GIFTr takes dataframe of questions of four types: multiple choices, numerical, true or false and short answer questions, and exports a text file formatted in MOODLE GIFT format. You can prepare a spreadsheet in any software and import it into R to generate any number of questions with HTML', markdown and LaTeX support.

In high-dimensional settings: Estimate the number of distant spikes based on the Generalized Spiked Population (GSP) model. Estimate the population eigenvalues, angles between the sample and population eigenvectors, correlations between the sample and population PC scores, and the asymptotic shrinkage factors. Adjust the shrinkage bias in the predicted PC scores. Dey, R. and Lee, S. (2019) <doi:10.1016/j.jmva.2019.02.007>.

This package implements some item response models for multiple ratings, including the hierarchical rater model, conditional maximum likelihood estimation of linear logistic partial credit model and a wrapper function to the commercial FACETS program. See Robitzsch and Steinfeld (2018) for a description of the functionality of the package. See Wang, Su and Qiu (2014; <doi:10.1111/jedm.12045>) for an overview of modeling alternatives.

Knowledge space theory by Doignon and Falmagne (1999) <doi:10.1007/978-3-642-58625-5> is a set- and order-theoretical framework which proposes mathematical formalisms to operationalize knowledge structures in a particular domain. The kstIO package provides basic functionalities to read and write KST data from/to files to be used together with the kst', kstMatrix', CDSS', pks', or DAKS packages.

Builds and interprets multi-response machine learning models using tidymodels syntax. Users can supply a tidy model, and mrIML automates the process of fitting multiple response models to multivariate data and applying interpretable machine learning techniques across them. For more details see Fountain-Jones (2021) <doi:10.1111/1755-0998.13495> and Fountain-Jones et al. (2024) <doi:10.22541/au.172676147.77148600/v1>.

This package contains functions useful for debugging, set operations on vectors, and UTC date and time functionality. It adds a few vector manipulation verbs to purrr and dplyr packages. It can also generate an R file to install and update packages to simplify deployment into production. The functions were developed at the data science firm Numeract LLC and are used in several packages and projects.

It includes four methods: DCOL-based K-profiles clustering, non-linear network reconstruction, non-linear hierarchical clustering, and variable selection for generalized additive model. References: Tianwei Yu (2018)<DOI: 10.1002/sam.11381>; Haodong Liu and others (2016)<DOI: 10.1371/journal.pone.0158247>; Kai Wang and others (2015)<DOI: 10.1155/2015/918954>; Tianwei Yu and others (2010)<DOI: 10.1109/TCBB.2010.73>.

Extracts and summarizes metadata from data frames, including variable names, labels, types, and missing values. Computes compact descriptive statistics, frequency tables, and cross-tabulations to assist with efficient data exploration. Includes an interactive and exportable codebook generator for documenting variable metadata. Facilitates the identification of missing data patterns and structural issues in datasets. Designed to streamline initial data management and exploratory analysis workflows within R'.

Different estimators are provided to solve the blind source separation problem for multivariate time series with stochastic volatility and supervised dimension reduction problem for multivariate time series. Different functions based on AMUSE and SOBI are also provided for estimating the dimension of the white noise subspace. The package is fully described in Nordhausen, Matilainen, Miettinen, Virta and Taskinen (2021) <doi:10.18637/jss.v098.i15>.

This package provides functions to compute Wasserstein barycenters of subset posteriors using the swapping algorithm developed by Puccetti, Rüschendorf and Vanduffel (2020) <doi:10.1016/j.jmaa.2017.02.003>. The Wasserstein barycenter is a geometric approach for combining subset posteriors. It allows for parallel and distributed computation of the posterior in case of complex models and/or big datasets, thereby increasing computational speed tremendously.

Latent variable modeling with Principal Component Analysis (PCA) and Partial Least Squares (PLS) are powerful methods for visualization, regression, classification, and feature selection of omics data where the number of variables exceeds the number of samples and with multicollinearity among variables. Orthogonal Partial Least Squares (OPLS) enables to separately model the variation correlated (predictive) to the factor of interest and the uncorrelated (orthogonal) variation. While performing similarly to PLS, OPLS facilitates interpretation.

This package provides imlementations of PCA, PLS, and OPLS for multivariate analysis and feature selection of omics data. In addition to scores, loadings and weights plots, the package provides metrics and graphics to determine the optimal number of components (e.g. with the R2 and Q2 coefficients), check the validity of the model by permutation testing, detect outliers, and perform feature selection (e.g. with Variable Importance in Projection or regression coefficients).

Fits linear models with endogenous regressor using latent instrumental variable approaches. The methods included in the package are Lewbel's (1997) <doi:10.2307/2171884> higher moments approach as well as Lewbel's (2012) <doi:10.1080/07350015.2012.643126> heteroscedasticity approach, Park and Gupta's (2012) <doi:10.1287/mksc.1120.0718> joint estimation method that uses Gaussian copula and Kim and Frees's (2007) <doi:10.1007/s11336-007-9008-1> multilevel generalized method of moment approach that deals with endogeneity in a multilevel setting. These are statistical techniques to address the endogeneity problem where no external instrumental variables are needed. See the publication related to this package in the Journal of Statistical Software for more details: <doi:10.18637/jss.v107.i03>. Note that with version 2.0.0 sweeping changes were introduced which greatly improve functionality and usability but break backwards compatibility.

The MBECS provides a set of functions to evaluate and mitigate unwated noise due to processing in batches. To that end it incorporates a host of batch correcting algorithms (BECA) from various packages. In addition it offers a correction and reporting pipeline that provides a preliminary look at the characteristics of a data-set before and after correcting for batch effects.

ravanan is a CWL implementation that is powered by GNU Guix and provides strong reproducibility guarantees. ravanan provides strong caching of intermediate results so the same step of a workflow is never run twice. ravanan captures logs from every step of the workflow for easy tracing back in case of job failures. ravanan currently runs on single machines and on slurm via its API.

There are a number of binary files associated with the Webdriver/Selenium project (see http://www.seleniumhq.org/download/, https://sites.google.com/a/chromium.org/chromedriver/, https://github.com/mozilla/geckodriver, http://phantomjs.org/download.html, and https://github.com/SeleniumHQ/selenium/wiki/InternetExplorerDriver for more information). This package provides functions to download these binaries and to manage processes involving them.

This package provides simple functions to compute and plot two types (sample-size- and coverage-based) rarefaction and extrapolation curves for species diversity (Hill numbers) based on individual-based abundance data or sampling-unit- based incidence data; see Chao and others (2014, Ecological Monographs) for pertinent theory and methodologies, and Hsieh, Ma and Chao (2016, Methods in Ecology and Evolution) for an introduction of the R package.

The Connectivity Map (CMap) is a massive resource of perturbational gene expression profiles built by researchers at the Broad Institute and funded by the NIH Library of Integrated Network-Based Cellular Signatures (LINCS) program. Please visit https://clue.io for more information. The cmapR package implements methods to parse, manipulate, and write common CMap data objects, such as annotated matrices and collections of gene sets.