This package provides a framework is provided to develop R packages using Rust <https://www.rust-lang.org/> with minimal overhead, and more wrappers are easily added. Help is provided to use Cargo <https://doc.rust-lang.org/cargo/> in a manner consistent with CRAN policies. Rust code can also be embedded directly in an R script. The package is not official, affiliated with, nor endorsed by the Rust project.

Gaussian mixture modeling of one- and two-dimensional data, provided in original or binned form, with an option to estimate the number of model components. The method uses Gaussian Mixture Models (GMM) with initial parameters determined by a dynamic programming algorithm, leading to stable and reproducible model fitting. For more details see Zyla, J., Szumala, K., Polanski, A., Polanska, J., & Marczyk, M. (2026) <doi:10.1016/j.jocs.2026.102811>.

This package provides time series regression models with one predictor using finite distributed lag models, polynomial (Almon) distributed lag models, geometric distributed lag models with Koyck transformation, and autoregressive distributed lag models. It also consists of functions for computation of h-step ahead forecasts from these models. See Demirhan (2020)(<doi:10.1371/journal.pone.0228812>) and Baltagi (2011)(<doi:10.1007/978-3-642-20059-5>) for more information.

R package to build and simulate deterministic compartmental models that can be non-Markovian. Length of stay in each compartment can be defined to follow a parametric distribution (d_exponential(), d_gamma(), d_weibull(), d_lognormal()) or a non-parametric distribution (nonparametric()). Other supported types of transition from one compartment to another includes fixed transition (constant()), multinomial (multinomial()), fixed transition probability (transprob()).

As in music, a fugue statistic repeats a theme in small variations. Here, the psi-function that defines an m-statistic is slightly altered to maintain the same design sensitivity in matched sets of different sizes. The main functions in the package are sen() and senCI(). For sensitivity analyses for m-statistics, see Rosenbaum (2007) Biometrics 63 456-464 <doi:10.1111/j.1541-0420.2006.00717.x>.

This package provides a comprehensive suite of functions and RStudio Add-ins leveraging the capabilities of open-source Large Language Models (LLMs) to support R developers. These functions offer a range of utilities, including text rewriting, translation, and general query capabilities. Additionally, the programming-focused functions provide assistance with debugging, translating, commenting, documenting, and unit testing code, as well as suggesting variable and function names, thereby streamlining the development process.

This package implements an efficient algorithm for fitting the entire regularization path of support vector machine models with elastic-net penalties using a generalized coordinate descent scheme. The framework also supports SCAD and MCP penalties. It is designed for high-dimensional datasets and emphasizes numerical accuracy and computational efficiency. This package implements the algorithms proposed in Tang, Q., Zhang, Y., & Wang, B. (2022) <https://openreview.net/pdf?id=RvwMTDYTOb>.

This package provides a systematic biology tool was developed to identify dysregulated miRNAs via a miRNA-miRNA interaction network. IDMIR first constructed a weighted miRNA interaction network through integrating miRNA-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific-disease context, and then, it used a network propagation algorithm on the network to identify significantly dysregulated miRNAs.

This package provides function to read data from the Igor Pro data analysis program by Wavemetrics'. The data formats supported are Igor packed experiment format ('pxp') and Igor binary wave ('ibw'). See: <https://www.wavemetrics.com/> for details. Also includes functions to load special pxp files produced by the Igor Pro Neuromatic and Nclamp packages for recording and analysing neuronal data. See <https://github.com/SilverLabUCL/NeuroMatic> for details.

Computing and plotting joint confidence regions and intervals. Regions include classical ellipsoids, minimum-volume or minimum-length regions, and an empirical Bayes region. Intervals include the TOST procedure with ordinary or expanded intervals and a fixed-sequence procedure. Such regions and intervals are useful e.g., for the assessment of multi-parameter (bio-)equivalence. Joint confidence regions for the mean and variance of a normal distribution are available as well.

Enables users to handle the dataset cleaning for conducting specific analyses with the log files from two international educational assessments: the Programme for International Student Assessment (PISA, <https://www.oecd.org/pisa/>) and the Programme for the International Assessment of Adult Competencies (PIAAC, <https://www.oecd.org/skills/piaac/>). An illustration of the analyses can be found on the LOGAN Shiny app (<https://loganpackage.shinyapps.io/shiny/>) on your browser.

This package provides a set of functions for analyzing the structure of forests based on the leaf area density (LAD) and leaf area index (LAI) measures calculated from Airborne Laser Scanning (ALS), i.e., scanning lidar (Light Detection and Ranging) data. The methodology is discussed and described in Almeida et al. (2019) <doi:10.3390/rs11010092> and Stark et al. (2012) <doi:10.1111/j.1461-0248.2012.01864.x>.

The reference implementation of model equations and default parameters for the toxicokinetic-toxicodynamic (TKTD) model of the Lemna (duckweed) aquatic plant. Lemna is a standard test macrophyte used in ecotox effect studies. The model was described and published by the SETAC Europe Interest Group Effect Modeling. It is a refined description of the Lemna TKTD model published by Schmitt et al. (2013) <doi:10.1016/j.ecolmodel.2013.01.017>.

This package provides functionality to generate compound optimal designs for targeting the multiple experimental objectives directly, ensuring that the full set of research questions is answered as economically as possible. Designs can be found using point or coordinate exchange algorithms combining estimation, inference and lack-of-fit criteria that account for model inadequacy. Details and examples are given by Koutra et al. (2024) <doi:10.48550/arXiv.2412.17158>.

This package implements linear and generalized linear models for provider profiling, incorporating both fixed and random effects. For large-scale providers, the linear profiled-based method and the SerBIN method for binary data reduce the computational burden. Provides post-modeling features, such as indirect and direct standardization measures, hypothesis testing, confidence intervals, and post-estimation visualization. For more information, see Wu et al. (2022) <doi:10.1002/sim.9387>.

This package provides a meta-package that aims to make R easier for everyone, especially programmers who have a background in SAS® software. This set of packages brings many useful concepts to R', including data libraries, data dictionaries, formats and format catalogs, a data step, and a traceable log. The system also includes a package that replicates several commonly-used SAS® procedures, like PROC FREQ', PROC MEANS', and PROC REG'.

Fit, compare, and visualize Bayesian graphical vector autoregressive (GVAR) network models using Stan'. These models are commonly used in psychology to represent temporal and contemporaneous relationships between multiple variables in intensive longitudinal data. Fitted models can be compared with a test based on matrix norm differences of posterior point estimates to quantify the differences between two estimated networks. See also Siepe, Kloft & Heck (2024) <doi:10.31234/osf.io/uwfjc>.

The "Vertical and Horizontal Inheritance Consistence Analysis" method is described in the following publication: "VHICA: a new method to discriminate between vertical and horizontal transposon transfer: application to the mariner family within Drosophila" by G. Wallau. et al. (2016) <DOI:10.1093/molbev/msv341>. The purpose of the method is to detect horizontal transfers of transposable elements, by contrasting the divergence of transposable element sequences with that of regular genes.

Within-subject mediation analysis using structural equation modeling. Examine how changes in an outcome variable between two conditions are mediated through one or more variables. Supports within-subject mediation analysis using the lavaan package by Rosseel (2012) <doi:10.18637/jss.v048.i02>, and extends Monte Carlo confidence interval estimation to missing data scenarios using the semmcci package by Pesigan and Cheung (2023) <doi:10.3758/s13428-023-02114-4>.

Edit XMP metadata <https://en.wikipedia.org/wiki/Extensible_Metadata_Platform> in a variety of media file formats as well as edit bookmarks (aka outline aka table of contents) and documentation info entries in pdf files. Can detect and use a variety of command-line tools to perform these operations such as exiftool <https://exiftool.org/>, ghostscript <https://www.ghostscript.com/>, and/or pdftk <https://gitlab.com/pdftk-java/pdftk>.

The biodb package provides access to standard remote chemical and biological databases (ChEBI, KEGG, HMDB, ...), as well as to in-house local database files (CSV, SQLite), with easy retrieval of entries, access to web services, search of compounds by mass and/or name, and mass spectra matching for LCMS and MSMS. Its architecture as a development framework facilitates the development of new database connectors for local projects or inside separate published packages.

The development of high-throughput sequencing led to increased use of co-expression analysis to go beyong single feature (i.e. gene) focus. We propose GWENA (Gene Whole co-Expression Network Analysis) , a tool designed to perform gene co-expression network analysis and explore the results in a single pipeline. It includes functional enrichment of modules of co-expressed genes, phenotypcal association, topological analysis and comparison of networks configuration between conditions.

This package enables the interpretation and analysis of results from a gene set enrichment analysis using network-based and text-mining approaches. Most enrichment analyses result in large lists of significant gene sets that are difficult to interpret. Tools in this package help build a similarity-based network of significant gene sets from a gene set enrichment analysis that can then be investigated for their biological function using text-mining approaches.

This package provides functions to perform the fitting of an adaptive mixture of Student-t distributions to a target density through its kernel function as described in Ardia et al. (2009) <doi:10.18637/jss.v029.i03>. The mixture approximation can then be used as the importance density in importance sampling or as the candidate density in the Metropolis-Hastings algorithm to obtain quantities of interest for the target density itself.