This is a package supporting cluster analysis for cognitive diagnosis based on the Asymptotic Classification Theory (Chiu, Douglas & Li, 2009; doi:10.1007/s11336-009-9125-0). Given the sample statistic of sum-scores, cluster analysis techniques can be used to classify examinees into latent classes based on their attribute patterns. In addition to the algorithms used to classify data, three labeling approaches are proposed to label clusters so that examinees' attribute profiles can be obtained.

This package provides qualitative methods for the validation of dynamic models. It contains

1. an orthogonal set of deviance measures for absolute, relative and ordinal scale and

2. approaches accounting for time shifts.

The first approach transforms time to take time delays and speed differences into account. The second divides the time series into interval units according to their main features and finds the longest common subsequence (LCS) using a dynamic programming algorithm.

Distance-correlation based Gene Set Analysis for longitudinal gene expression profiles. In longitudinal studies, the gene expression profiles were collected at each visit from each subject and hence there are multiple measurements of the gene expression profiles for each subject. The dcGSA package could be used to assess the associations between gene sets and clinical outcomes of interest by fully taking advantage of the longitudinal nature of both the gene expression profiles and clinical outcomes.

TRIP is a software framework that provides analytics services on antigen receptor (B cell receptor immunoglobulin, BcR IG | T cell receptor, TR) gene sequence data. It is a web application written in R Shiny. It takes as input the output files of the IMGT/HighV-Quest tool. Users can select to analyze the data from each of the input samples separately, or the combined data files from all samples and visualize the results accordingly.

This package provides a powerful tool for automating the early detection of disease outbreaks in time series data. aeddo employs advanced statistical methods, including hierarchical models, in an innovative manner to effectively characterize outbreak signals. It is particularly useful for epidemiologists, public health professionals, and researchers seeking to identify and respond to disease outbreaks in a timely fashion. For a detailed reference on hierarchical models, consult Henrik Madsen and Poul Thyregod's book (2011), ISBN: 9781420091557.

This package implements a basis function or functional data analysis framework for several techniques of multivariate analysis in continuous-time setting. Specifically, we introduced continuous-time analogues of several classical techniques of multivariate analysis, such as principal component analysis, canonical correlation analysis, Fisher linear discriminant analysis, K-means clustering, and so on. Details are in Biplab Paul, Philip T. Reiss, Erjia Cui and Noemi Foa (2025) "Continuous-time multivariate analysis" <doi: 10.1080/10618600.2024.2374570>.

Statistical tests for the comparison between two correlations based on either independent or dependent groups. Dependent correlations can either be overlapping or nonoverlapping. A web interface is available on the website <http://comparingcorrelations.org>. A plugin for the R GUI and IDE RKWard is included. Please install RKWard from <https://rkward.kde.org> to use this feature. The respective R package rkward cannot be installed directly from a repository, as it is a part of RKWard.

Decomposing value added growth into explanatory factors. A cost constrained value added function is defined to specify the production frontier. Industry estimates can also be aggregated using a weighted average approach. Details about the methodology and data can be found in Diewert and Fox (2018) <doi:10.1093/oxfordhb/9780190226718.013.19> and Zeng, Parsons, Diewert and Fox (2018) <https://www.business.unsw.edu.au/research-site/centreforappliedeconomicresearch-site/Documents/emg2018-6_SZeng_EMG-Slides.pdf>.

Plot an R package's recursive dependency graph and tabulate the number of unique downstream dependencies added by top-level dependencies. This helps R package developers identify which of their declared dependencies add the most downstream dependencies in order to prioritize them for removal if needed. Uses graph stress minimization adapted from Schoch (2023) <doi:10.21105/joss.05238> and originally reported in Gansner et al. (2004) <doi:10.1007/978-3-540-31843-9_25>.

This package contains data on Post-Secondary Institution Statistics in 2020 <https://nces.ed.gov/ipeds/use-the-data>. The package allows easy access to a wide variety of information regarding Post-secondary Institutions, its students, faculty, and their demographics, financial aid, educational and recreational offerings, and completions. This package can be used by students, college counselors, or involved parents interested in pursuing higher education, considering their options, and securing admission into their school of choice.

Surface topography calculations of Dirichlet's normal energy, relief index, surface slope, and orientation patch count for teeth using scans of enamel caps. Importantly, for the relief index and orientation patch count calculations to work, the scanned tooth files must be oriented with the occlusal plane parallel to the x and y axes, and perpendicular to the z axis. The files should also be simplified, and smoothed in some other software prior to uploading into R.

The implemented methods reach out to scientists that seek to estimate multiplicity of infection (MOI) and lineage (allele) frequencies and prevalences at molecular markers using the maximum-likelihood method described in Schneider (2018) <doi:10.1371/journal.pone.0194148>, and Schneider and Escalante (2014) <doi:10.1371/journal.pone.0097899>. Users can import data from Excel files in various formats, and perform maximum-likelihood estimation on the imported data by the package's moimle() function.

Optimal experimental designs for both population and individual studies based on nonlinear mixed-effect models. Often this is based on a computation of the Fisher Information Matrix. This package was developed for pharmacometric problems, and examples and predefined models are available for these types of systems. The methods are described in Nyberg et al. (2012) <doi:10.1016/j.cmpb.2012.05.005>, and Foracchia et al. (2004) <doi:10.1016/S0169-2607(03)00073-7>.

Check available classification and regression data sets from the PMLB repository and download them. The PMLB repository (<https://github.com/EpistasisLab/pmlbr>) contains a curated collection of data sets for evaluating and comparing machine learning algorithms. These data sets cover a range of applications, and include binary/multi-class classification problems and regression problems, as well as combinations of categorical, ordinal, and continuous features. There are currently over 150 datasets included in the PMLB repository.

This package provides functions to estimate, predict and interpolate areal data. For estimation and prediction we assume areal data is an average of an underlying continuous spatial process as in Moraga et al. (2017) <doi:10.1016/j.spasta.2017.04.006>, Johnson et al. (2020) <doi:10.1186/s12942-020-00200-w>, and Wilson and Wakefield (2020) <doi:10.1093/biostatistics/kxy041>. The interpolation methodology is (mostly) based on Goodchild and Lam (1980, ISSN:01652273).

This package provides several functions for area level of small area estimation using hierarchical Bayesian (HB) methods with several univariate distributions for variables of interest. The dataset that is used in every function is generated accordingly in the Example. The rjags package is employed to obtain parameter estimates. Model-based estimators involve the HB estimators which include the mean and the variation of mean. For the reference, see Rao and Molina (2015) <doi:10.1002/9781118735855>.

R implementation of the software tools developed in the H-CUP (Healthcare Cost and Utilization Project) <https://hcup-us.ahrq.gov> and AHRQ (Agency for Healthcare Research and Quality) <https://www.ahrq.gov>. It currently contains functions for mapping ICD-9 codes to the AHRQ comorbidity measures and translating ICD-9 (resp. ICD-10) codes to ICD-10 (resp. ICD-9) codes based on GEM (General Equivalence Mappings) from CMS (Centers for Medicare and Medicaid Services).

BiFET identifies transcription factors (TFs) whose footprints are over-represented in target regions compared to background regions after correcting for the bias arising from the imbalance in read counts and GC contents between the target and background regions. For a given TF k, BiFET tests the null hypothesis that the target regions have the same probability of having footprints for the TF k as the background regions while correcting for the read count and GC content bias.

The package aims to identify miRNA sponge or ceRNA modules in heterogeneous data. It provides several functions to study miRNA sponge modules at single-sample and multi-sample levels, including popular methods for inferring gene modules (candidate miRNA sponge or ceRNA modules), and two functions to identify miRNA sponge modules at single-sample and multi-sample levels, as well as several functions to conduct modular analysis of miRNA sponge modules.

This package contains functions for the MCMC simulation of dyadic network models j2 (Zijlstra, 2017, <doi:10.1080/0022250X.2017.1387858>) and p2 (Van Duijn, Snijders & Zijlstra, 2004, <doi: 10.1046/j.0039-0402.2003.00258.x>), the multilevel p2 model (Zijlstra, Van Duijn & Snijders (2009) <doi: 10.1348/000711007X255336>), and the bidirectional (multilevel) counterpart of the the multilevel p2 model as described in Zijlstra, Van Duijn & Snijders (2009) <doi: 10.1348/000711007X255336>, the (multilevel) b2 model.

Efficient procedures for fitting the DD-PCA (Ke et al., 2019, <arXiv:1906.00051>) by decomposing a large covariance matrix into a low-rank matrix plus a diagonally dominant matrix. The implementation of DD-PCA includes the convex approach using the Alternating Direction Method of Multipliers (ADMM) and the non-convex approach using the iterative projection algorithm. Applications of DD-PCA to large covariance matrix estimation and global multiple testing are also included in this package.

Joint dimension reduction and spatial clustering is conducted for Single-cell RNA sequencing and spatial transcriptomics data, and more details can be referred to Wei Liu, Xu Liao, Yi Yang, Huazhen Lin, Joe Yeong, Xiang Zhou, Xingjie Shi and Jin Liu. (2022) <doi:10.1093/nar/gkac219>. It is not only computationally efficient and scalable to the sample size increment, but also is capable of choosing the smoothness parameter and the number of clusters as well.

Simulates cyclic voltammetry, linear-sweep voltammetry (both with and without stirring of the solution), and single-pulse and double-pulse chronoamperometry and chronocoulometry experiments using the implicit finite difference method outlined in Gosser (1993, ISBN: 9781560810261) and in Brown (2015) <doi:10.1021/acs.jchemed.5b00225>. Additional functions provide ways to display and to examine the results of these simulations. The primary purpose of this package is to provide tools for use in courses in analytical chemistry.

This package provides a novel forward stepwise discriminant analysis framework that integrates Pillai's trace with Uncorrelated Linear Discriminant Analysis (ULDA), providing an improvement over traditional stepwise LDA methods that rely on Wilks Lambda. A stand-alone ULDA implementation is also provided, offering a more general solution than the one available in the MASS package. It automatically handles missing values and provides visualization tools. For more details, see Wang (2024) <doi:10.48550/arXiv.2409.03136>.