This package provides a high-level, object-oriented interface for Secure File Transfer Protocol (SFTP) operations built upon the curl package. The package implements an R6 class to manage persistent connections and provides tidyverse'-style functions for common file system tasks. Key features include recursive directory creation with idempotency support, "smart" local path resolution that distinguishes between files and directories, and the ability to download remote resources directly into memory as raw vectors for seamless integration into data processing pipelines. It is designed to handle common SFTP edge cases gracefully, providing informative error messages and robust path sanitization to ensure compatibility across different server configurations.

This is a modification of HDoutliers package. The HDoutliers algorithm is a powerful unsupervised algorithm for detecting anomalies in high-dimensional data, with a strong theoretical foundation. However, it suffers from some limitations that significantly hinder its performance level, under certain circumstances. This package implements the algorithm proposed in Talagala, Hyndman and Smith-Miles (2019) <arXiv:1908.04000> for detecting anomalies in high-dimensional data that addresses these limitations of HDoutliers algorithm. We define an anomaly as an observation that deviates markedly from the majority with a large distance gap. An approach based on extreme value theory is used for the anomalous threshold calculation.

This package is an implementation of a regularized regression prediction and empirical Bayes method to recover the true gene expression profile in noisy and sparse single-cell RNA-seq data. In single-cell RNA sequencing (scRNA-seq) studies, only a small fraction of the transcripts present in each cell are sequenced. This leads to unreliable quantification of genes with low or moderate expression, which hinders downstream analysis. This package single-cell analysis via expression recovery (SAVER) implements an expression recovery method for unique molecule index (UMI)-based scRNA-seq data that borrows information across genes and cells to provide accurate expression estimates for all genes.

Several cubic spline interpolation methods of H. Akima for irregular and regular gridded data are available through this package, both for the bivariate case (irregular data: ACM 761, regular data: ACM 760) and univariate case (ACM 433 and ACM 697). Linear interpolation of irregular gridded data is also covered by reusing D. J. Renkas triangulation code which is part of Akimas Fortran code. A bilinear interpolator for regular grids was also added for comparison with the bicubic interpolator on regular grids. Please note that most of the functions are now also covered in package interp, which is a re-implementation from scratch under a free license.

This package provides the C++ header-only library barry for use in R packages. barry is a C++ template library for counting sufficient statistics on binary arrays and building discrete exponential-family models. It provides tools for sparse arrays, user-defined count statistics, support set constraints, power set generation, and includes modules for Discrete Exponential Family Models (DEFMs) and network statistics. By placing these headers in this package, we offer an efficient distribution system for CRAN as replication of this code in the sources of other packages is avoided. This package follows the same approach as the BH package which provides Boost headers for R packages.

This package implements Bayesian spatio-temporal factor analysis models for multivariate data observed across space and time. The package provides tools for model fitting via Markov chain Monte Carlo (MCMC), spatial and temporal interpolation, and visualization of latent factors and loadings to support inference and exploration of underlying spatio-temporal patterns. Designed for use in environmental, ecological, or public health applications, with support for posterior prediction and uncertainty quantification. Includes functions such as BSTFA() for model fitting and plot_factor() to visualize the latent processes. Functions are based on and extended from methods described in Berrett, et al. (2020) <doi:10.1002/env.2609>.

An R package for iterative and batched record linkage, and applying epidemiological case definitions. diyar can be used for deterministic and probabilistic record linkage, or multistage record linkage combining both approaches. It features the implementation of nested match criteria, and mechanisms to address missing data and conflicting matches during stepwise record linkage. Case definitions are implemented by assigning records to groups based on match criteria such as person or place, and overlapping time or duration of events e.g. sample collection dates or periods of hospital stays. Matching records are assigned a unique group ID. Index and duplicate records are removed or further analyses as required.

Implementation of the Hysteretic and Gatekeeping Depressions Model (HGDM) which calculates variable connected/contributing areas and resulting discharge volumes in prairie basins dominated by depressions ("slough" or "potholes"). The small depressions are combined into a single "meta" depression which explicitly models the hysteresis between the storage of water and the connected/contributing areas of the depressions. The largest (greater than 5% of the total depressional area) depression (if it exists) is represented separately to model its gatekeeping, i.e. the blocking of upstream flows until it is filled. The methodolgy is described in detail in Shook and Pomeroy (2025, <doi:10.1016/j.jhydrol.2025.132821>).

This package performs variable selection for many types of L1-regularised regressions using the revisited knockoffs procedure. This procedure uses a matrix of knockoffs of the covariates independent from the response variable Y. The idea is to determine if a covariate belongs to the model depending on whether it enters the model before or after its knockoff. The procedure suits for a wide range of regressions with various types of response variables. Regression models available are exported from the R packages glmnet and ordinalNet'. Based on the paper linked to via the URL below: Gegout A., Gueudin A., Karmann C. (2019) <arXiv:1907.03153>.

Implementation of the Swiss Confederation's standard analysis model for salary analyses <www.ebg.admin.ch/en/equal-pay-analysis-with-logib> in R. The analysis is run at company-level and the model is intended for medium-sized and large companies. It can technically be used with 50 or more employees (apprentices, trainees/interns and expats are not included in the analysis). Employees with at least 100 employees are required by the Gender Equality Act to conduct an equal pay analysis. This package allows users to run the equal salary analysis in R, providing additional transparency with respect to the methodology and simple automation possibilities.

Based on the input data an n-dimensional cube with sub cells of user specified side length is created. The number of sample points which fall in each sub cube is counted, and with the cell volume and overall sample size an empirical probability can be computed. A number of cubes of higher resolution can be superimposed. The basic method stems from J.L. Bentley in "Multidimensional Divide and Conquer". J. L. Bentley (1980) <doi:10.1145/358841.358850>. Furthermore a simple kernel density estimation method is made available, as well as an expansion of Bentleys method, which offers a kernel approach for the grid method.

Statistical models for specific coronavirus disease 2019 use cases at German local health authorities. All models of Statistical modelling for infectious disease management smidm are part of the decision support toolkit in the EsteR project. More information is published in Sonja Jäckle, Rieke Alpers, Lisa Kühne, Jakob Schumacher, Benjamin Geisler, Max Westphal "'EsteR â A Digital Toolkit for COVID-19 Decision Support in Local Health Authorities" (2022) <doi:10.3233/SHTI220799> and Sonja Jäckle, Elias Röger, Volker Dicken, Benjamin Geisler, Jakob Schumacher, Max Westphal "A Statistical Model to Assess Risk for Supporting COVID-19 Quarantine Decisions" (2021) <doi:10.3390/ijerph18179166>.

Partial application is the process of reducing the arity of a function by fixing one or more arguments, thus creating a new function lacking the fixed arguments. The curry package provides three different ways of performing partial function application by fixing arguments from either end of the argument list (currying and tail currying) or by fixing multiple named arguments (partial application). This package provides this functionality through the %<%, %-<%, and %><% operators which allows for a programming style comparable to modern functional languages. Compared to other implementations such a purrr::partial() the operators in curry composes functions with named arguments, aiding in autocomplete etc.

Calculate AZTIâ s Marine Biotic Index - AMBI. The included list of benthic fauna species according to their sensitivity to pollution. Matching species in sample data to the list allows the calculation of fractions of individuals in the different sensitivity categories and thereafter the AMBI index. The Shannon Diversity Index H and the Danish benthic fauna quality index DKI (Dansk Kvalitetsindeks) can also be calculated, as well as the multivariate M-AMBI index. Borja, A., Franco, J. ,Pérez, V. (2000) "A marine biotic index to establish the ecological quality of soft bottom benthos within European estuarine and coastal environments" <doi:10.1016/S0025-326X(00)00061-8>.

The Philippines frequently experiences tropical cyclones (called bagyo in the Filipino language) because of its geographical position. These cyclones typically bring heavy rainfall, leading to widespread flooding, as well as strong winds that cause significant damage to human life, crops, and property. Data on cyclones are collected and curated by the Philippine Atmospheric, Geophysical, and Astronomical Services Administration or PAGASA and made available through its website <https://bagong.pagasa.dost.gov.ph/tropical-cyclone/publications/annual-report>. This package contains Philippine tropical cyclones data in a machine-readable format. It is hoped that this data package provides an interesting and unique dataset for data exploration and visualisation.

This package implements several spatial and spatio-temporal scalable disease mapping models for high-dimensional count data using the INLA technique for approximate Bayesian inference in latent Gaussian models (Orozco-Acosta et al., 2021 <doi:10.1016/j.spasta.2021.100496>; Orozco-Acosta et al., 2023 <doi:10.1016/j.cmpb.2023.107403> and Vicente et al., 2023 <doi:10.1007/s11222-023-10263-x>). The creation and develpment of this package has been supported by Project MTM2017-82553-R (AEI/FEDER, UE) and Project PID2020-113125RB-I00/MCIN/AEI/10.13039/501100011033. It has also been partially funded by the Public University of Navarra (project PJUPNA2001).

An implementation of Conic Multivariate Adaptive Regression Splines (CMARS) in R. See Weber et al. (2011) CMARS: a new contribution to nonparametric regression with multivariate adaptive regression splines supported by continuous optimization, <DOI:10.1080/17415977.2011.624770>. It constructs models by using the terms obtained from the forward step of MARS and then estimates parameters by using Tikhonov regularization and conic quadratic optimization. It is possible to construct models for prediction and binary classification. It provides performance measures for the model developed. The package needs the optimisation software MOSEK <https://www.mosek.com/> to construct the models. Please follow the instructions in Rmosek for the installation.

Three methods are implemented in R to facilitate the aggregations of flags in official statistics. From the underlying flags the highest in the hierarchy, the most frequent, or with the highest total weight is propagated to the flag(s) for EU or other aggregates. Below there are some reference documents for the topic: <https://sdmx.org/wp-content/uploads/CL_OBS_STATUS_v2_1.docx>, <https://sdmx.org/wp-content/uploads/CL_CONF_STATUS_1_2_2018.docx>, <http://ec.europa.eu/eurostat/data/database/information>, <http://www.oecd.org/sdd/33869551.pdf>, <https://sdmx.org/wp-content/uploads/CL_OBS_STATUS_implementation_20-10-2014.pdf>.

This package implements the integrative conditional autoregressive horseshoe model discussed in Jendoubi, T., Ebbels, T.M. Integrative analysis of time course metabolic data and biomarker discovery. BMC Bioinformatics 21, 11 (2020) <doi:10.1186/s12859-019-3333-0>. The model consists in three levels: Metabolic pathways level modeling interdependencies between variables via a conditional auto-regressive (CAR) component, integrative analysis level to identify potential associations between heterogeneous omic variables via a Horseshoe prior and experimental design level to capture experimental design conditions through a mixed-effects model. The package also provides functions to simulate data from the model, construct pathway matrices, post process and plot model parameters.

Estimate haplotypic or composite pairwise linkage disequilibrium (LD) in polyploids, using either genotypes or genotype likelihoods. Support is provided to estimate the popular measures of LD: the LD coefficient D, the standardized LD coefficient D', and the Pearson correlation coefficient r. All estimates are returned with corresponding standard errors. These estimates and standard errors can then be used for shrinkage estimation. The main functions are ldfast(), ldest(), mldest(), sldest(), plot.lddf(), format_lddf(), and ldshrink(). Details of the methods are available in Gerard (2021a) <doi:10.1111/1755-0998.13349> and Gerard (2021b) <doi:10.1038/s41437-021-00462-5>.

This package implements the synthetic control group method for comparative case studies as described in Abadie and Gardeazabal (2003) and Abadie, Diamond, and Hainmueller (2010, 2011, 2014). The synthetic control method allows for effect estimation in settings where a single unit (a state, country, firm, etc.) is exposed to an event or intervention. It provides a data-driven procedure to construct synthetic control units based on a weighted combination of comparison units that approximates the characteristics of the unit that is exposed to the intervention. A combination of comparison units often provides a better comparison for the unit exposed to the intervention than any comparison unit alone.

This package provides a tool for non linear mapping (non linear regression) using a mixture of regression model and an inverse regression strategy. The methods include the GLLiM model (see Deleforge et al (2015) <DOI:10.1007/s11222-014-9461-5>) based on Gaussian mixtures and a robust version of GLLiM, named SLLiM (see Perthame et al (2016) <DOI:10.1016/j.jmva.2017.09.009>) based on a mixture of Generalized Student distributions. The methods also include BLLiM (see Devijver et al (2017) <arXiv:1701.07899>) which is an extension of GLLiM with a sparse block diagonal structure for large covariance matrices (particularly interesting for transcriptomic data).

R package for analysis of transcript and translation features through manipulation of sequence data and NGS data like Ribo-Seq, RNA-Seq, TCP-Seq and CAGE. It is generalized in the sense that any transcript region can be analysed, as the name hints to it was made with investigation of ribosomal patterns over Open Reading Frames (ORFs) as it's primary use case. ORFik is extremely fast through use of C++, data.table and GenomicRanges. Package allows to reassign starts of the transcripts with the use of CAGE-Seq data, automatic shifting of RiboSeq reads, finding of Open Reading Frames for whole genomes and much more.

This package provides a Python based pipeline for extraction of species occurrence data through the usage of large language models. Includes validation tools designed to handle model hallucinations for a scientific, rigorous use of LLM. Currently supports usage of GPT with more planned, including local and non-proprietary models. For more details on the methodology used please consult the references listed under each function, such as Kent, A. et al. (1995) <doi:10.1002/asi.5090060209>, van Rijsbergen, C.J. (1979, ISBN:978-0408709293, Levenshtein, V.I. (1966) <https://nymity.ch/sybilhunting/pdf/Levenshtein1966a.pdf> and Klaus Krippendorff (2011) <https://repository.upenn.edu/handle/20.500.14332/2089>.