This package provides a fast and efficient implementation of Sobol sequences for quasi-Monte Carlo methods. The Sobol sequence is a low-discrepancy sequence with the property that for all values of N, its subsequence x1, ..., xN has a low discrepancy. It can be used to generate quasi-random numbers for use in Monte Carlo integration and other simulation methods. This implementation is based on the algorithms described by Bratley and Fox (1988) <doi:10.1145/42288.214372> and uses direction numbers from Joe and Kuo (2008) <doi:10.1145/1358628.1358630>. The package includes both batch and incremental interfaces with support for arbitrary starting indices and reproducible sequences. It uses Rcpp for efficient C++ integration.

Fit linear, logistic and Cox models regularized with L0, lasso (L1), elastic-net (L1 and L2), or net (L1 and Laplacian) penalty, and their adaptive forms, such as adaptive lasso / elastic-net and net adjusting for signs of linked coefficients. It solves the L0 penalty problem by simultaneously selecting regularization parameters and performing hard-thresholding or selecting the number of non-zeros. This augmented and penalized minimization method provides an approximation solution to the L0 penalty problem, but runs as fast as L1 regularization. The package uses a one-step coordinate descent algorithm and runs extremely fast by taking into account the sparsity structure of coefficients. It can handle very high dimensional data and has superior selection performance.

This package performs binary classification via Group Method of Data Handling (GMDH) - type neural network algorithms. There exist two main algorithms available in GMDH() and dceGMDH() functions. GMDH() performs classification via GMDH algorithm for a binary response and returns important variables. dceGMDH() performs classification via diverse classifiers ensemble based on GMDH (dce-GMDH) algorithm. Also, the package produces a well-formatted table of descriptives for a binary response. Moreover, it produces confusion matrix, its related statistics and scatter plot (2D and 3D) with classification labels of binary classes to assess the prediction performance. All GMDH2 functions are designed for a binary response (Dag et al., 2019, <https://download.atlantis-press.com/article/125911202.pdf>).

Data and utilities for estimating pediatric blood pressure percentiles by sex, age, and optionally height (stature) as described in Martin et al. (2022) <doi:10.1001/jamanetworkopen.2022.36918>. Blood pressure percentiles for children under one year of age come from Gemelli et al. (1990) <doi:10.1007/BF02171556>. Estimates of blood pressure percentiles for children at least one year of age are informed by data from the National Heart, Lung, and Blood Institute (NHLBI) and the Centers for Disease Control and Prevention (CDC) <doi:10.1542/peds.2009-2107C> or from Lo et al. (2013) <doi:10.1542/peds.2012-1292>. The source-selection flowchart comes from Martin et al. (2022) <doi:10.1542/hpeds.2021-005998>.

This package is a implementation of biclustering ensemble method MoSBi (Molecular signature Identification from Biclustering). MoSBi provides standardized interfaces for biclustering results and can combine their results with a multi-algorithm ensemble approach to compute robust ensemble biclusters on molecular omics data. This is done by computing similarity networks of biclusters and filtering for overlaps using a custom error model. After that, the louvain modularity it used to extract bicluster communities from the similarity network, which can then be converted to ensemble biclusters. Additionally, MoSBi includes several network visualization methods to give an intuitive and scalable overview of the results. MoSBi comes with several biclustering algorithms, but can be easily extended to new biclustering algorithms.

This package provides a compact C++ backend for Approximate Bayesian Computation (ABC) with a thin R frontend. The current implementation is primarily a C++ reimplementation of offline ABC workflows provided by the R abc package <doi:10.32614/CRAN.package.abc>, with the public R interface intentionally kept small and centered on abc() and summary() methods. The computational work is performed by shared C++ code. In addition to reproducing common abc workflows, the package adds optional dimensionality reduction of summary statistics through Principal Component Analysis (PCA) and Partial Least Squares (PLS), following related ideas described by Bazin et al. (2010) <doi:10.1534/genetics.109.112391> and Wegmann et al. (2009) <doi:10.1534/genetics.109.102509>.

This package provides a set of tools to perform Ecological Niche Modeling with presence-absence data. It includes algorithms for data partitioning, model fitting, calibration, evaluation, selection, and prediction. Other functions help to explore signals of ecological niche using univariate and multivariate analyses, and model features such as variable response curves and variable importance. Unique characteristics of this package are the ability to exclude models with concave quadratic responses, and the option to clamp model predictions to specific variables. These tools are implemented following principles proposed in Cobos et al., (2022) <doi:10.17161/bi.v17i.15985>, Cobos et al., (2019) <doi:10.7717/peerj.6281>, and Peterson et al., (2008) <doi:10.1016/j.ecolmodel.2007.11.008>.

This package provides R bindings to the GGML tensor library for machine learning, optimized for Vulkan GPU acceleration with a transparent CPU fallback. The package features a Keras'-like sequential API and a PyTorch'-style autograd engine for building, training, and deploying neural networks. Key capabilities include high-performance 5D tensor operations, f16 precision, and efficient quantization. It supports native ONNX model import (50+ operators) and GGUF weight loading from the llama.cpp and Hugging Face ecosystems. Designed for zero-overhead inference via dedicated weight buffering, it integrates seamlessly as a parsnip engine for tidymodels and provides first-class learners for the mlr3 framework. See <https://github.com/ggml-org/ggml> for more information about the underlying library.

The accurate annotation of genes and Quantitative Trait Loci (QTLs) located within candidate markers and/or regions (haplotypes, windows, CNVs, etc) is a crucial step the most common genomic analyses performed in livestock, such as Genome-Wide Association Studies or transcriptomics. The Genomic Annotation in Livestock for positional candidate LOci (GALLO) is an R package designed to provide an intuitive and straightforward environment to annotate positional candidate genes and QTLs from high-throughput genetic studies in livestock. Moreover, GALLO allows the graphical visualization of gene and QTL annotation results, data comparison among different grouping factors (e.g., methods, breeds, tissues, statistical models, studies, etc.), and QTL enrichment in different livestock species including cattle, pigs, sheep, and chicken, among others.

Conducting Line transect-based one-dimensional nearest neighbor distance and conducting hypothesis testing related to local distributional aggregation pattern of species. The reason that such a package is needed is because traditional two-dimensional nearest neighbor distance is not applicable when biodiversity data are sampled via optimal ecological survey methods, like line transects. In comparison to the entire studied region, line transect-collected local biodiversity data are spatially constrained and sampling-limited. To this end, two-dimensional nearest neighbor distance would tend to over-estimate distributional aggregation pattern of species when using this limited biodiversity information. Accordingly, one-dimensional nearest neighbor distance is needed and the associated statistical testing should be established for analyzing line transect-derived biodiversity data.

Solves the Multi-Criteria Minimum Spanning Tree (mc-MST) problem on complete weighted graphs by combining the Non-dominated Sorting Genetic Algorithm II (NSGA-II) with optional Pareto local search operators. Chromosomes are represented as Prufer sequences so that every random individual decodes to a valid spanning tree (Cayley's theorem), avoiding repair operators. Four solver variants are provided: pure NSGA-II ("base"), Path Relinking ("PR"), Pareto Local Search ("PLS"), and Tabu Search ("TS"). The package supports 2 and 3 objective formulations and provides convenience functions to plot Pareto fronts and best-compromise spanning trees. This package is the reference implementation of the method described in Parraga-Alava, Inostroza-Ponta and Dorn (2017) <doi:10.1109/CEC.2017.7969432>.

Performs unconditional exact tests and power calculations for 2x2 contingency tables. For comparing two independent proportions, performs Barnard's test (1945) using the original CSM test (Barnard (1947)), using Fisher's p-value referred to as Boschloo's test (1970), or using a Z-statistic (Suissa and Shuster (1985)). For comparing two binary proportions, performs unconditional exact test using McNemar's Z-statistic (Berger and Sidik (2003)), using McNemar's Z-statistic with continuity correction, or using CSM test. Calculates confidence intervals for the difference in proportion.

Evaluates land suitability for different crops production. The package is based on the Food and Agriculture Organization (FAO) and the International Rice Research Institute (IRRI) methodology for land evaluation. Development of ALUES is inspired by similar tool for land evaluation, Land Use Suitability Evaluation Tool (LUSET). The package uses fuzzy logic approach to evaluate land suitability of a particular area based on inputs such as rainfall, temperature, topography, and soil properties. The membership functions used for fuzzy modeling are the following: Triangular, Trapezoidal and Gaussian. The methods for computing the overall suitability of a particular area are also included, and these are the Minimum, Maximum and Average. Finally, ALUES is a highly optimized library with core algorithms written in C++.

This package provides various basis expansions for flexible regression modeling, including random Fourier features (Rahimi & Recht, 2007) <https://proceedings.neurips.cc/paper_files/paper/2007/file/013a006f03dbc5392effeb8f18fda755-Paper.pdf>, exact kernel / Gaussian process feature maps, prior features for Bayesian Additive Regression Trees (BART) (McCartan & Huang, 2026) <doi:10.48550/arXiv.2607.28844>, and a helpful interface for n-way interactions. The provided functions may be used within any modeling formula, allowing the use of kernel methods and other basis expansions in modeling functions that do not otherwise support them. Along with the basis expansions, a number of kernel functions are also provided, which support kernel arithmetic to form new kernels. Basic ridge regression functionality is included as well.

This package provides a Shiny application to conduct comprehensive analysis of latent means including the examination of group equivalency, propensity score analysis, measurement invariance analysis, and assessment of latent mean differences of equivalent groups with invariant data. Group equivalency and propensity score analyses are implemented using the MatchIt package [Ho et al. (2011) <doi:10.18637/jss.v042.i08>], ensuring robust control for covariates. Structural equation modeling and invariance testing rely heavily on the lavaan package [Rosseel (2012) <doi:10.18637/jss.v048.i02>], providing a flexible and powerful modeling framework. The application also integrates modified functions from Hammack-Brown et al. (2021) <doi:10.1002/hrdq.21452> to support factor ratio testing and the list-and-delete procedure.

This package implements a unified predictive framework in which individual parameters are decomposed as theta_i equal to theta_ref plus Delta(x_i, theta_ref), with theta_ref a population reference and Delta an explicit deviation function. The decomposition follows the Additive-Multiplicative-Modulated canonical form and is estimated through three complementary paths: hierarchical Bayesian inference via Stan', varying-coefficient models via penalized splines, and amortized inference via hypernetworks in torch'. The package provides identifiability diagnostics, validity tests for the population reference, and benchmarks against canonical zero-inflated count datasets and avian abundance data from the eBird Status and Trends project. The framework and its estimation paths are described in Gomez Julian (2026) <doi:10.5281/zenodo.21046269>.

This package provides a Modern and Flexible Neo4J Driver, allowing you to query data on a Neo4J server and handle the results in R. It's modern in the sense it provides a driver that can be easily integrated in a data analysis workflow, especially by providing an API working smoothly with other data analysis and graph packages. It's flexible in the way it returns the results, by trying to stay as close as possible to the way Neo4J returns data. That way, you have the control over the way you will compute the results. At the same time, the result is not too complex, so that the "heavy lifting" of data wrangling is not left to the user.

This package provides helper functions to compute linear predictors, time-dependent ROC curves, and Harrell's concordance index for Cox proportional hazards models as described in Therneau (2024) <https://CRAN.R-project.org/package=survival>, Therneau and Grambsch (2000, ISBN:0-387-98784-3), Hung and Chiang (2010) <doi:10.1002/cjs.10046>, Uno et al. (2007) <doi:10.1198/016214507000000149>, Blanche, Dartigues, and Jacqmin-Gadda (2013) <doi:10.1002/sim.5958>, Blanche, Latouche, and Viallon (2013) <doi:10.1007/978-1-4614-8981-8_11>, Harrell et al. (1982) <doi:10.1001/jama.1982.03320430047030>, Peto and Peto (1972) <doi:10.2307/2344317>, Schemper (1992) <doi:10.2307/2349009>, and Uno et al. (2011) <doi:10.1002/sim.4154>.

Gcrma adjusts for background intensities in Affymetrix array data which include optical noise and non-specific binding (NSB). The main function gcrma converts background adjusted probe intensities to expression measures using the same normalization and summarization methods as a Robust Multiarray Average (RMA). Gcrma uses probe sequence information to estimate probe affinity to NSB. The sequence information is summarized in a more complex way than the simple GC content. Instead, the base types (A, T, G or C) at each position along the probe determine the affinity of each probe. The parameters of the position-specific base contributions to the probe affinity is estimated in an NSB experiment in which only NSB but no gene-specific binding is expected.

Inference based on models with or without spatially-correlated random effects, multivariate responses, or non-Gaussian random effects (e.g., Beta). Variation in residual variance (heteroscedasticity) can itself be represented by a mixed-effect model. Both classical geostatistical models (Rousset and Ferdy 2014 <doi:10.1111/ecog.00566>), and Markov random field models on irregular grids (as considered in the INLA package, <https://www.r-inla.org>), can be fitted, with distinct computational procedures exploiting the sparse matrix representations for the latter case and other autoregressive models. Laplace approximations are used for likelihood or restricted likelihood. Penalized quasi-likelihood and other variants discussed in the h-likelihood literature (Lee and Nelder 2001 <doi:10.1093/biomet/88.4.987>) are also implemented.

This package provides a Cairo graphics device that can be use to create high-quality vector (PDF, PostScript and SVG) and bitmap output (PNG, JPEG, TIFF), and high-quality rendering in displays (X11 and Win32). Since it uses the same back-end for all output, copying across formats is WYSIWYG. Files are created without the dependence on X11 or other external programs. This device supports alpha channel (semi-transparent drawing) and resulting images can contain transparent and semi-transparent regions. It is ideal for use in server environments (file output) and as a replacement for other devices that don't have Cairo's capabilities such as alpha support or anti-aliasing. Backends are modular such that any subset of backends is supported.

This package provides interface to the MATLAB toolbox Flexible Statistical Data Analysis (FSDA) which is comprehensive and computationally efficient software package for robust statistics in regression, multivariate and categorical data analysis. The current R version implements tools for regression: (forward search, S- and MM-estimation, least trimmed squares (LTS) and least median of squares (LMS)), for multivariate analysis (forward search, S- and MM-estimation), for cluster analysis and cluster-wise regression. The distinctive feature of our package is the possibility of monitoring the statistics of interest as a function of breakdown point, efficiency or subset size, depending on the estimator. This is accompanied by a rich set of graphical features, such as dynamic brushing, linking, particularly useful for exploratory data analysis.

This package provides three S7 classes â streamline, bundle, and bundle_set â for representing diffusion MRI tractography data in R, together with a concise set of methods for computing shape descriptors (arc-length, curvature, torsion, sinuosity), the Hausdorff distance between streamlines, arc-length reparametrization of streamlines and bundles onto uniform grids, combination of streamlines or bundles into a single bundle, combination of bundles from multiple subjects or sessions into a bundle_set, and coercion to and from the dwiFiber S4 class of the dti package. See Dell'Acqua, F., Descoteaux, M. and Leemans, A. (2024) "Handbook of Diffusion MR Tractography" <doi:10.1016/C2018-0-02520-7> for more about the mathematical and computational underpinnings of diffusion MRI tractography.

This package provides a model that provides researchers with a powerful tool for the classification and study of native corn by aiding in the identification of racial complexes which are fundamental to Mexico's agriculture and culture. This package has been developed based on data collected by "Proyecto Global de Maà ces Nativos México", which has conducted exhaustive surveys across the country to document the qualitative and quantitative characteristics of different types of native maize. The trained model uses a robust and diverse dataset, enabling it to achieve an 80% accuracy in classifying maize racial complexes. The characteristics included in the analysis comprise geographic location, grain and cob colors, as well as various physical measurements, such as lengths and widths.