Spatio-temporal multivariate occupancy models can handle multiple species in occupancy models. This method for fitting such models is described in Hepler and Erhardt (2021) "A spatiotemporal model for multivariate occupancy data" <https://onlinelibrary.wiley.com/doi/abs/10.1002/env.2657>.

Network meta-analysis and network meta-regression models for aggregate data, individual patient data, and mixtures of both individual and aggregate data using multilevel network meta-regression as described by Phillippo et al. (2020) <doi:10.1111/rssa.12579>. Models are estimated in a Bayesian framework using Stan'.

Multi-criteria design of experiments algorithm that simultaneously optimizes up to six different criteria ('I', Id', D', Ds', A and As'). The algorithm finds the optimal Pareto front and, if requested, selects a possible symmetrical design on it. The symmetrical design is selected based on two techniques: minimum distance with the Utopia point or the TOPSIS approach.

This package provides a collection of microRNAs/targets from external resources, including validated microRNA-target databases (miRecords, miRTarBase and TarBase), predicted microRNA-target databases (DIANA-microT, ElMMo, MicroCosm, miRanda, miRDB, PicTar, PITA and TargetScan) and microRNA-disease/drug databases (miR2Disease, Pharmaco-miR VerSe and PhenomiR).

This package provides a toolkit containing statistical analysis models motivated by multivariate forms of the Conway-Maxwell-Poisson (COM-Poisson) distribution for flexible modeling of multivariate count data, especially in the presence of data dispersion. Currently the package only supports bivariate data, via the bivariate COM-Poisson distribution described in Sellers et al. (2016) <doi:10.1016/j.jmva.2016.04.007>. Future development will extend the package to higher-dimensional data.

This package provides tools to solve real-world problems with multiple classes classifications by computing the areas under ROC and PR curve via micro-averaging and macro-averaging. The vignettes of this package can be found via <https://github.com/WandeRum/multiROC>. The methodology is described in V. Van Asch (2013) <https://www.clips.uantwerpen.be/~vincent/pdf/microaverage.pdf> and Pedregosa et al. (2011) <http://scikit-learn.org/stable/auto_examples/model_selection/plot_roc.html>.

This package provides a collection of functions for converting and visualization the free induction decay of mono dimensional nuclear magnetic resonance (NMR) spectra into an audio file. It facilitates the conversion of Bruker datasets in files WAV. The sound of NMR signals could provide an alternative to the current representation of the individual metabolic fingerprint and supply equally significant information. The package includes also NMR spectra of the urine samples provided by four healthy donors. Based on Cacciatore S, Saccenti E, Piccioli M. Hypothesis: the sound of the individual metabolic phenotype? Acoustic detection of NMR experiments. OMICS. 2015;19(3):147-56. <doi:10.1089/omi.2014.0131>.

This package provides a set of tools to facilitate data sonification and handle the musicXML format <https://usermanuals.musicxml.com/MusicXML/Content/XS-MusicXML.htm>. Several classes are defined for basic musical objects such as note pitch, note duration, note, measure and score. Moreover, sonification utilities functions are provided, e.g. to map data into musical attributes such as pitch, loudness or duration. A typical sonification workflow hence looks like: get data; map them to musical attributes; create and write the musicXML score, which can then be further processed using specialized music software (e.g. MuseScore', GuitarPro', etc.). Examples can be found in the blog <https://globxblog.github.io/>, the presentation by Renard and Le Bescond (2022, <https://hal.science/hal-03710340v1>) or the poster by Renard et al. (2023, <https://hal.inrae.fr/hal-04388845v1>).

This package provides a set of functions which use the Expectation Maximisation (EM) algorithm (Dempster, A. P., Laird, N. M., and Rubin, D. B. (1977) <doi:10.1111/j.2517-6161.1977.tb01600.x> Maximum likelihood from incomplete data via the EM algorithm, Journal of the Royal Statistical Society, 39(1), 1--22) to take a finite mixture model approach to clustering. The package is designed to cluster multivariate data that have categorical and continuous variables and that possibly contain missing values. The method is described in Hunt, L. and Jorgensen, M. (1999) <doi:10.1111/1467-842X.00071> Australian & New Zealand Journal of Statistics 41(2), 153--171 and Hunt, L. and Jorgensen, M. (2003) <doi:10.1016/S0167-9473(02)00190-1> Mixture model clustering for mixed data with missing information, Computational Statistics & Data Analysis, 41(3-4), 429--440.

Dichotomous responses having two categories can be analyzed with stats::glm() or lme4::glmer() using the family=binomial option. Unfortunately, polytomous responses with three or more unordered categories cannot be analyzed similarly because there is no analogous family=multinomial option. For between-subjects data, nnet::multinom() can address this need, but it cannot handle random factors and therefore cannot handle repeated measures. To address this gap, we transform nominal response data into counts for each categorical alternative. These counts are then analyzed using (mixed) Poisson regression as per Baker (1994) <doi:10.2307/2348134>. Omnibus analyses of variance can be run along with post hoc pairwise comparisons. For users wishing to analyze nominal responses from surveys or experiments, the functions in this package essentially act as though stats::glm() or lme4::glmer() provide a family=multinomial option.

Mutational signatures are carcinogenic exposures or aberrant cellular processes that can cause alterations to the genome. We created musicatk (MUtational SIgnature Comprehensive Analysis ToolKit) to address shortcomings in versatility and ease of use in other pre-existing computational tools. Although many different types of mutational data have been generated, current software packages do not have a flexible framework to allow users to mix and match different types of mutations in the mutational signature inference process. Musicatk enables users to count and combine multiple mutation types, including SBS, DBS, and indels. Musicatk calculates replication strand, transcription strand and combinations of these features along with discovery from unique and proprietary genomic feature associated with any mutation type. Musicatk also implements several methods for discovery of new signatures as well as methods to infer exposure given an existing set of signatures. Musicatk provides functions for visualization and downstream exploratory analysis including the ability to compare signatures between cohorts and find matching signatures in COSMIC V2 or COSMIC V3.

Documentation at https://melpa.org/#/muban

Documentation at https://melpa.org/#/mugur

Documentation at https://melpa.org/#/multi

Estimates gene expressions from several laser scans of the same microarray.

This package provides a graphical user interface for the MuToss Project.

This package provides An async parser for `multipart/form-data` content-type in Rust.

FHCRC Genomics Shared Resource Mu15v1 Annotation Data (Mu15v1) assembled using data from public repositories.

FHCRC Genomics Shared Resource Mu22v3 Annotation Data (Mu22v3) assembled using data from public repositories.

Data package containing a multi-sample multi-group spatial dataset in SpatialExperiment Bioconductor object format.

This package performs genetic association tests between SNPs (one-at-a-time) and multiple phenotypes (separately or in joint model).

Extracted features from pathways derived from 8 different databases (KEGG, Reactome, Biocarta, etc.) can be used on transcriptomic, proteomic, and/or metabolomic level to calculate a combined GSEA-based enrichment score.

Computes the third multivariate cumulant of either the raw, centered or standardized data. Computes the main measures of multivariate skewness, together with their bootstrap distributions. Finally, computes the least skewed linear projections of the data.

Analyze multilevel networks as described in Lazega et al (2008) <doi:10.1016/j.socnet.2008.02.001> and in Lazega and Snijders (2016, ISBN:978-3-319-24520-1). The package was developed essentially as an extension to igraph'.