This package provides a toolset for functional enrichment analysis and visualization, gene/protein/SNP identifier conversion and mapping orthologous genes across species via g:Profiler. The main tools are:

1. g:GOSt, functional enrichment analysis and visualization of gene lists;

2. g:Convert, gene/protein/transcript identifier conversion across various namespaces;

3. g:Orth, orthology search across species;

4. g:SNPense, mapping SNP rs identifiers to chromosome positions, genes and variant effects.

This package is an R interface corresponding to the 2019 update of g:Profiler and provides access to versions e94_eg41_p11 and higher.

This package provides gradient projection algorithms for factor rotation. For details see ?GPArotation.

Derivative Free Gradient Projection Algorithms for Factor Rotation. For more details see ?GPArotateDF. Theory for these functions can be found in the following publications: Jennrich (2004) <doi:10.1007/BF02295647>. Bernaards and Jennrich (2005) <doi:10.1177/0013164404272507>.

Gaussian processes are flexible distributions to model functional data. Whilst theoretically appealing, they are computationally cumbersome except for small datasets. This package implements two methods for scaling Gaussian process inference in Stan'. First, a sparse approximation of the likelihood that is generally applicable and, second, an exact method for regularly spaced data modeled by stationary kernels using fast Fourier methods. Utility functions are provided to compile and fit Stan models using the cmdstanr interface. References: Hoffmann and Onnela (2025) <doi:10.18637/jss.v112.i02>.

This package provides a Bayesian statistical model for estimating child (under-five age group) and adult (15-60 age group) mortality. The main challenge is how to combine and integrate these different time series and how to produce unified estimates of mortality rates during a specified time span. GPR is a Bayesian statistical model for estimating child and adult mortality rates which its data likelihood is mortality rates from different data sources such as: Death Registration System, Censuses or surveys. There are also various hyper-parameters for completeness of DRS, mean, covariance functions and variances as priors. This function produces estimations and uncertainty (95% or any desirable percentiles) based on sampling and non-sampling errors due to variation in data sources. The GP model utilizes Bayesian inference to update predicted mortality rates as a posterior in Bayes rule by combining data and a prior probability distribution over parameters in mean, covariance function, and the regression model. This package uses Markov Chain Monte Carlo (MCMC) to sample from posterior probability distribution by rstan package in R. Details are given in Wang H, Dwyer-Lindgren L, Lofgren KT, et al. (2012) <doi:10.1016/S0140-6736(12)61719-X>, Wang H, Liddell CA, Coates MM, et al. (2014) <doi:10.1016/S0140-6736(14)60497-9> and Mohammadi, Parsaeian, Mehdipour et al. (2017) <doi:10.1016/S2214-109X(17)30105-5>.