We fit causal models using proxies. We implement two stage proximal least squares estimator. E.J. Tchetgen Tchetgen, A. Ying, Y. Cui, X. Shi, and W. Miao. (2020). An Introduction to Proximal Causal Learning. arXiv e-prints, arXiv-2009 <arXiv:2009.10982>.

Estimates the parameters of a Transformed Ornstein-Uhlenbeck (TOU) stochastic model for adsorption data and also the parameters of the related pseudo-n-order (PNO) model, such as the maximum adsorption capacity (qe), the adsorption rate constant (kn) and the order of the model (n).

The mia package implements tools for microbiome analysis based on the SummarizedExperiment, SingleCellExperiment and TreeSummarizedExperiment infrastructure. Data wrangling and analysis in the context of taxonomic data is the main scope. Additional functions for common task are implemented such as community indices calculation and summarization.

RSeQC provides a number of modules that can comprehensively evaluate high throughput sequence data, especially RNA-seq data. Some basic modules inspect sequence quality, nucleotide composition bias, PCR bias and GC bias, while RNA-seq specific modules evaluate sequencing saturation, mapped reads distribution, coverage uniformity, strand specificity, etc.

This package offers a flexible, feature-rich yet light-weight logging framework based on R6 classes. It supports hierarchical loggers, custom log levels, arbitrary data fields in log events, logging to plaintext, JSON, (rotating) files, memory buffers, and databases, as well as email and push notifications.

This package provides basic functions, implemented in C, for large data manipulation. Fast vectorised ifelse()/nested if()/switch() functions, psum()/pprod() functions equivalent to pmin()/pmax() plus others which are missing from base R. Most of these functions are callable at C level.

This is a package for ratios of count data such as obtained from RNA-seq are modelled using Bayesian statistics to derive posteriors for effects sizes. This approach is described in Erhard & Zimmer (2015) <doi:10.1093/nar/gkv696> and Erhard (2018) <doi:10.1093/bioinformatics/bty471>.

RHash is a console utility for calculation and verification of magnet links and a wide range of hash sums like CRC32, MD4, MD5, SHA1, SHA256, SHA512, SHA3, AICH, ED2K, Tiger, DC++ TTH, BitTorrent BTIH, GOST R 34.11-94, RIPEMD-160, HAS-160, EDON-R, Whirlpool and Snefru.

Calculates some antecedent discharge conditions useful in water quality modeling. Includes methods for calculating flow anomalies, base flow, and smooth discounted flows from daily flow measurements. Antecedent discharge algorithms are described and reviewed in Zhang and Ball (2017) <doi:10.1016/j.jhydrol.2016.12.052>.

For multiscale analysis, this package carries out empirical mode decomposition and Hilbert spectral analysis. For usage of EMD, see Kim and Oh, 2009 (Kim, D and Oh, H.-S. (2009) EMD: A Package for Empirical Mode Decomposition and Hilbert Spectrum, The R Journal, 1, 40-46).

Forest-based statistical estimation and inference. GRF provides non-parametric methods for heterogeneous treatment effects estimation (optionally using right-censored outcomes, multiple treatment arms or outcomes, or instrumental variables), as well as least-squares regression, quantile regression, and survival regression, all with support for missing covariates.

Hard drive data: Class of data allowing the easy importation/manipulation of out of memory data sets. The data sets are located on disk but look like in-memory, the syntax for manipulation is similar to data.table'. Operations are performed "chunk-wise" behind the scene.

Let us consider a sample of patients who can suffer from several diseases simultaneously, in a given set of diseases. The goal of the implemented algorithm is to estimate the individual average cost of each disease, starting from the global health costs available for each patient.

This package provides a collection of tools intended to make introductory statistics easier to teach, including wrappers for common hypothesis tests and basic data manipulation. It accompanies Navarro, D. J. (2015). Learning Statistics with R: A Tutorial for Psychology Students and Other Beginners, Version 0.6.

Given the date column as an ascending entry, future errors are included in the sum of squares of error that should be minimized based on the number of steps and weights you determine. Thus, it is prevented that the variables affect each other's coefficients unrealistically.

This package provides bitmapped vectors of booleans (no NAs), coercion from and to logicals, integers and integer subscripts, fast boolean operators and fast summary statistics. With bit class vectors of true binary booleans, TRUE and FALSE can be stored with 1 bit only.

This package contains methods for calculating Interaction Based Homogeneity to evaluate fitness of gene lists to an interaction network which is useful for evaluation of clustering results and gene list analysis. BioGRID interactions are used in the calculation. The user can also provide their own interactions.

This package provides an S3 class to represent graph adjacency lists using vctrs'. Allows for creation, subsetting, combining, and pretty printing of these lists. Adjacency lists can be easily converted to zero-indexed lists, which allows for easy passing of objects to low-level languages for processing.

This package provides a collection of S4 classes which implements different methods to estimate and deal with densities in bounded domains. That is, densities defined within the interval [lower.limit, upper.limit], where lower.limit and upper.limit are values that can be set by the user.

This package implements cluster-polarization coefficient for measuring distributional polarization in single or multiple dimensions, as well as associated functions. Contains support for hierarchical clustering, k-means, partitioning around medoids, density-based spatial clustering with noise, and manually imposed cluster membership. Mehlhaff (2024) <doi:10.1017/S0003055423001041>.

This package provides density, distribution function, quantile function and random generation for the split normal and split-t distributions, and computes their mean, variance, skewness and kurtosis for the two distributions (Li, F, Villani, M. and Kohn, R. (2010) <doi:10.1016/j.jspi.2010.04.031>).

Fuzzy set ordination is a multivariate analysis used in ecology to relate the composition of samples to possible explanatory variables. While differing in theory and method, in practice, the use is similar to constrained ordination. The package contains plotting and summary functions as well as the analyses.

Methodology for subgroup selection in the context of isotonic regression including methods for sub-Gaussian errors, classification, homoscedastic Gaussian errors and quantile regression. See the documentation of ISS(). Details can be found in the paper by Müller, Reeve, Cannings and Samworth (2023) <arXiv:2305.04852v2>.

Local Mean Decomposition is an iterative and self-adaptive approach for demodulating, processing, and analyzing multi-component amplitude modulated and frequency modulated signals. This R package is based on the approach suggested by Smith (2005) <doi:10.1098/rsif.2005.0058> and the Python library PyLMD'.