This package provides tools to estimate parameters of accumulated damage (load duration) models based on failure time data under a Bayesian framework, using Approximate Bayesian Computation (ABC), and to assess long-term reliability under stochastic load profiles.

RabbitMQ is a messaging and streaming broker that supports multiple messaging protocols, including AMQP 1.0 and MQTT 5.0. It offers features such as message routing, filtering, streaming, federation, and clustering. It is designed for reliability and flexibility.

Infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision.

This package provides `dplyr` verbs (`mutate`, `select`, `filter`, etc...) supporting `S4Vectors::DataFrame` objects. Importantly, this is achieved without conversion to an intermediate `tibble`. Adds grouping infrastructure to `DataFrame` which is respected by the transformation verbs.

Raw data downloaded from GEO for the compound LY294002. Raw data is from multiple platforms from Affymetrix and Illumina. This data is used to illustrate the cross-platform meta-analysis of microarray data using the crossmeta package.

Toolbox for larger-than-memory scientific computing and visualization, providing efficient out-of-core data structures using files or shared memory, for dense and sparse vectors, matrices, and arrays, with applications to nonuniformly sampled signals and images.

Assorted utilities for multi-modal analyses of single-cell datasets. Includes functions to combine multiple modalities for downstream analysis, perform MNN-based batch correction across multiple modalities, and to compute correlations between assay values for different modalities.

This package contains R functions to predict biological variables to from placnetal DNA methylation data generated from infinium arrays. This includes inferring ethnicity/ancestry, gestational age, and cell composition from placental DNA methylation array (450k/850k) data.

SIGHTS is a suite of normalization methods, statistical tests, and diagnostic graphical tools for high throughput screening (HTS) assays. HTS assays use microtitre plates to screen large libraries of compounds for their biological, chemical, or biochemical activity.

This package provides tools to read/write/publish metadata based on the Atom XML syndication format. This includes support of Dublin Core XML implementation, and a client to API(s) implementing the AtomPub - SWORD API specification.

Simulation and pricing routines for rare-event options using Adaptive Multilevel Splitting and standard Monte Carlo under Black-Scholes and Heston models. Core routines are implemented in C++ via Rcpp and RcppArmadillo with lightweight R wrappers.

Fit Bayesian Regression Additive Trees (BART) models to select true confounders from a large set of potential confounders and to estimate average treatment effect. For more information, see Kim et al. (2023) <doi:10.1111/biom.13833>.

This package provides a penalized/non-penalized implementation for dynamic regression in the presence of autocorrelated residuals (DREGAR) using iterative penalized/ordinary least squares. It applies Mallows CP, AIC, BIC and GCV to select the tuning parameters.

Leverages dplyr to process the calculations of a plot inside a database. This package provides helper functions that abstract the work at three levels: outputs a ggplot', outputs the calculations, outputs the formula needed to calculate bins.

Implementation of DetMCD, a new algorithm for robust and deterministic estimation of location and scatter. The benefits of robust and deterministic estimation are explained in Hubert, Rousseeuw and Verdonck (2012) <doi:10.1080/10618600.2012.672100>.

Measurement and partitioning of diversity, based on Tsallis entropy, following Marcon and Herault (2015) <doi:10.18637/jss.v067.i08>. divent provides functions to estimate alpha, beta and gamma diversity of communities, including phylogenetic and functional diversity.

This package provides a set of functions, which facilitates removing objects from an environment. It allows to delete objects specified with regular expression or with other conditions (e.g. if object is numeric), using one function call.

Detects sustained change in digital bio-marker data using simultaneous confidence bands. Accounts for noise using an auto-regressive model. Based on Buehlmann (1998) "Sieve bootstrap for smoothing in nonstationary time series" <doi:10.1214/aos/1030563978>.

This package provides tools and features for "Exploratory Landscape Analysis (ELA)" of single-objective continuous optimization problems. Those features are able to quantify rather complex properties, such as the global structure, separability, etc., of the optimization problems.

New kernel-based test and fast tests for detecting change-points or changed-intervals where the distributions abruptly change. They work well particularly for high-dimensional data. Song, H. and Chen, H. (2022) <arXiv:2206.01853>.

Mixtures of skewed and elliptical distributions are implemented using mixtures of multivariate skew power exponential and power exponential distributions, respectively. A generalized expectation-maximization framework is used for parameter estimation. See citation() for how to cite.

Data sets in the book entitled "Multivariate Statistical Methods with R Applications", H.Bulut (2018). The book was published in Turkish and the original name of this book will be "R Uygulamalari ile Cok Degiskenli Istatistiksel Yontemler".

Homogeneity tests of the coefficients in panel data. Currently, only the Hsiao test for determining coefficient homogeneity between the panel data individuals is implemented, as described in Hsiao (2022), "Analysis of Panel Data" (<doi:10.1017/9781009057745>).

Perform flexible simulation studies using one or multiple computer cores. The package is set up to be usable on high-performance clusters in addition to being run locally, see examples on <https://github.com/SachaEpskamp/parSim>.