Bivariate data interpolation on regular and irregular grids, either linear or using splines are the main part of this package. It is intended to provide replacement functions for the ACM licensed akima::interp and tripack::tri.mesh functions.

This package contains microarray gene expression data generated from the Connectivity Map build 02 and LINCS l1000. The data are used by the ccmap package to find drugs and drug combinations to mimic or reverse a gene expression signature.

DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

epiNEM is an extension of the original Nested Effects Models (NEM). EpiNEM is able to take into account double knockouts and infer more complex network signalling pathways. It is tailored towards large scale double knock-out screens.

Fits from simple regression to highly customizable deep neural networks either with gradient descent or metaheuristic, using automatic hyper parameters tuning and custom cost function. A mix inspired by the common tricks on Deep Learning and Particle Swarm Optimization.

This package provides functions to fit the binomial and multinomial additive hazard models and to estimate the contribution of diseases/conditions to the disability prevalence, as proposed by Nusselder and Looman (2004) and extended by Yokota et al (2017).

Easy-to-use tools for performing complex queries on avidaDB', a semantic database that stores genomic and transcriptomic data of self-replicating computer programs (known as digital organisms) that mutate and evolve within a user-defined computational environment.

Bayesian models for accurately estimating conditional distributions by race, using Bayesian Improved Surname Geocoding (BISG) probability estimates of individual race. Implements the methods described in McCartan, Fisher, Goldin, Ho and Imai (2025) <doi:10.1080/01621459.2025.2526695>.

This package provides a lossless compressed data format that uses a combination of the LZ77 algorithm and Huffman coding <https://www.rfc-editor.org/rfc/rfc7932>. Brotli is similar in speed to deflate (gzip) but offers more dense compression.

This package provides functions that format statistical output in a way that can be inserted into R Markdown documents. This is analogous to the apa_print() functions in the papaja package but prints Markdown or LaTeX syntax.

Implementation of the d/p/q/r family of functions for a continuous analog to the standard discrete binomial with continuous size parameter and continuous support with x in [0, size + 1], following Ilienko (2013) <arXiv:1303.5990>.

Dynamic stochastic block model that combines a stochastic block model (SBM) for its static part with independent Markov chains for the evolution of the nodes groups through time, developed in Matias and Miele (2016) <doi:10.1111/rssb.12200>.

Model cell type heterogeneity of bulk renal cell carcinoma. The observed gene expression in bulk tumor sample is modeled by a log-normal distribution with the location parameter structured as a linear combination of the component-specific gene expressions.

Routines for Bayesian estimation and analysis of dynamic quantile linear models utilizing the extended asymmetric Laplace error distribution, also known as extended dynamic quantile linear models (exDQLM) described in Barata et al (2020) <doi:10.1214/21-AOAS1497>.

This package provides functions for covariance matrix comparisons, estimation of repeatabilities in measurements and matrices, and general evolutionary quantitative genetics tools. Melo D, Garcia G, Hubbe A, Assis A P, Marroig G. (2016) <doi:10.12688/f1000research.7082.3>.

Reads cell contents plus formatting from a spreadsheet file and creates an editable gt object with the same data and formatting. Supports the most commonly-used cell and text styles including colors, fills, font weights and decorations, and borders.

Preview what a ggplot2 plot would look like if you save it to a file. Attach picture dimensions as a canvas() element and get an instant preview. These dimensions will then be used when you save the plot.

Works with ggplot2 to add a Van Gogh color palette to the userâ s repertoire. It also has a function that work alongside ggplot2 to create more interesting data visualizations and add contextual information to the userâ s plots.

Audio interactivity within shiny applications using howler.js'. Enables the status of the audio player to be sent from the UI to the server, and events such as playing and pausing the audio can be triggered from the server.

Performing Item Response Theory analysis such as parameter estimation, ability estimation, data generation, item and model fit analyse, local independence assumption, dimensionality assumption, wright map, characteristic and information curves under various models with a user-friendly Graphic User Interface.

An R client for the ipbase.com IP Geolocation API. The API requires registration of an API key. Basic features are free, some require a paid subscription. You can find the full API documentation at <https://ipbase.com/docs> .

This package provides a variety of ordination and community analyses useful in analysis of data sets in community ecology. Includes many of the common ordination methods, with graphical routines to facilitate their interpretation, as well as several novel analyses.

The main objective of this package is to support the definition of Moodle elements taking advantage of the power that R offers. In this first version, it allows the definition of quizzes to be included in the question bank.

Micro simulation model to reproduce natural history of cervical cancer and cost-effectiveness evaluation of prevention strategies. See Georgalis L, de Sanjose S, Esnaola M, Bosch F X, Diaz M (2016) <doi:10.1097/CEJ.0000000000000202> for more details.