This package provides tools for interacting with data from experiments done in microtiter plates. Easily read in plate-shaped data and convert it to tidy format, combine plate-shaped data with tidy data, and view tidy data in plate shape.

Estimation and inference for parameters in a Gaussian copula model, treating the univariate marginal distributions as nuisance parameters as described in Hoff (2007) <doi:10.1214/07-AOAS107>. This package also provides a semiparametric imputation procedure for missing multivariate data.

Given raster files directly downloaded from various websites, it generates a raster structure where it merges them if they are tiles of the same scene and classifies them according to their spectral and spatial resolution for easy access by name.

This package provides a set of reliable routines to ease semiparametric survival regression modeling based on Bernstein polynomials. spsurv includes proportional hazards, proportional odds and accelerated failure time frameworks for right-censored data. RV Panaro (2020) <arXiv:2003.10548>.

This package provides a simple interface to search available data provided by Theia (<https://theia.cnes.fr>), download it, and manage it. Data can be downloaded based on a search result or from a cart file downloaded from Theia website.

This package implements differential language analysis with statistical tests and offers various language visualization techniques for n-grams and topics. It also supports the text package. For more information, visit <https://r-topics.org/> and <https://www.r-text.org/>.

Simulation, exploratory data analysis and Bayesian analysis of the p-order Integer-valued Autoregressive (INAR(p)) and Zero-inflated p-order Integer-valued Autoregressive (ZINAR(p)) processes, as described in Garay et al. (2020) <doi:10.1080/00949655.2020.1754819>.

Restricted Cubic Splines were performed to explore the shape of association form of "U, inverted U, L" shape and test linearity or non-linearity base on "Cox,Logistic,linear,quasipoisson" regression, and auto output Restricted Cubic Splines figures. rcssci package could automatically draw RCS graphics with Y-axis "OR,HR,RR,beta". The Restricted Cubic Splines method were based on Suli Huang (2022) <doi:10.1016/j.ecoenv.2022.113183>,Amit Kaura (2019) <doi:10.1136/bmj.l6055>, and Harrell Jr (2015, ISBN:978-3-319-19424-0 (Print) 978-3-319-19425-7 (Online)).

Doubly ranked tests are nonparametric tests for grouped functional and multivariate data. The testing procedure first ranks a matrix (or three dimensional array) of data by column (if a matrix) or by cell (across the third dimension if an array). By default, it calculates a sufficient statistic for the subject's order within the sample using the observed ranks, taken over the columns or cells. Depending on the number of groups, G, the summarized ranks are then analyzed using either a Wilcoxon Rank Sum test (G = 2) or a Kruskal-Wallis (G greater than 2).

This package provides a framework for the analysis and exploration of single-cell chromatin data. The Signac package contains functions for quantifying single-cell chromatin data, computing per-cell quality control metrics, dimension reduction and normalization, visualization, and DNA sequence motif analysis.

This package provides type-stable rolling window functions over any R data type. Cumulative and expanding windows are also supported. For more advanced usage, an index can be used as a secondary vector that defines how sliding windows are to be created.

This package provides a structured S4 approach to importing data files from the 10X pipelines. It mainly supports Single Cell Multiome ATAC + Gene Expression data among other data types. The main Bioconductor data representations used are SingleCellExperiment and RaggedExperiment.

Design primers for targeted single-cell RNA-seq used by TAP-seq. Create sequence templates for target gene panels and design gene-specific primers using Primer3. Potential off-targets can be estimated with BLAST. Requires working installations of Primer3 and BLASTn.

This package provides WHO Child Growth Standards (z-scores) with confidence intervals and standard errors around the prevalence estimates, taking into account complex sample designs. More information on the methods is available online: <https://www.who.int/tools/child-growth-standards>.

Lightweight validation tool for checking function arguments and validating data analysis scripts. This is an alternative to stopifnot() from the base package and to assert_that() from the assertthat package. It provides more informative error messages and facilitates debugging.

Causal discovery in linear structural equation models (Schultheiss, and Bühlmann (2023) <doi:10.1093/biomet/asad008>) and vector autoregressive models (Schultheiss, Ulmer, and Bühlmann (2025) <doi:10.1515/jci-2024-0011>) with explicit error control for false discovery, at least asymptotically.

Dose-response modeling for negative-binomial distributed data with a variety of dose-response models. Covariate adjustment and Bayesian model averaging is supported. Functions are provided to easily obtain inference on the dose-response relationship and plot the dose-response curve.

This package provides functions to produce some circular plots for circular data, in a height- or area-proportional manner. They include bar plots, smooth density plots, stacked dot plots, histograms, multi-class stacked smooth density plots, and multi-class stacked histograms.

This package provides a clustered random forest algorithm for fitting random forests for data of independent clusters, that exhibit within cluster dependence. Details of the method can be found in Young and Buehlmann (2025) <doi:10.48550/arXiv.2503.12634>.

This package provides functions for nonlinear regression parameters estimation by algorithms based on Controlled Random Search algorithm. Both functions (crs4hc(), crs4hce()) adapt current search strategy by four heuristics competition. In addition, crs4hce() improves adaptability by adaptive stopping condition.

Differential Analysis of short RNA transcripts that can be modeled by either Poisson or Negative binomial distribution. The statistical methodology implemented in this package is based on the random selection of references genes (Desaulle et al. (2021) <arXiv:2103.09872>).

Simplifies and automates the process of exploring and merging data from relational databases. This package allows users to discover table relationships, create a map of all possible joins, and generate executable plans to merge data based on a structured metadata framework.

This package contains published data sets for global benthic d18O data for 0-5.3 Myr <doi:10.1029/2004PA001071> and global sea levels based on marine sediment core data for 0-800 ka <doi:10.5194/cp-12-1-2016>.

Implementations of the treatment effect estimators for hybrid (self-selection) experiments, as developed by Brian J. Gaines and James H. Kuklinski, (2011), "Experimental Estimation of Heterogeneous Treatment Effects Related to Self-Selection," American Journal of Political Science 55(3): 724-736.