This package provides unified syntax to write data from lazy dplyr tbl or dplyr sql query or a dataframe to a database table with modes such as create, append, insert, update, upsert, patch, delete, overwrite, overwrite_schema.

Setting layout through YAML headers in R-Markdown documents, enabling their automatic generation. Functions and methods may summarize R objects in automatic reports, for instance check-lists and further reports applied to the packages taxlist and vegtable'.

Infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision.

This package provides `dplyr` verbs (`mutate`, `select`, `filter`, etc...) supporting `S4Vectors::DataFrame` objects. Importantly, this is achieved without conversion to an intermediate `tibble`. Adds grouping infrastructure to `DataFrame` which is respected by the transformation verbs.

Raw data downloaded from GEO for the compound LY294002. Raw data is from multiple platforms from Affymetrix and Illumina. This data is used to illustrate the cross-platform meta-analysis of microarray data using the crossmeta package.

The MADSEQ package provides a group of hierarchical Bayeisan models for the detection of mosaic aneuploidy, the inference of the type of aneuploidy and also for the quantification of the fraction of aneuploid cells in the sample.

Assorted utilities for multi-modal analyses of single-cell datasets. Includes functions to combine multiple modalities for downstream analysis, perform MNN-based batch correction across multiple modalities, and to compute correlations between assay values for different modalities.

Toolbox for larger-than-memory scientific computing and visualization, providing efficient out-of-core data structures using files or shared memory, for dense and sparse vectors, matrices, and arrays, with applications to nonuniformly sampled signals and images.

This package contains R functions to predict biological variables to from placnetal DNA methylation data generated from infinium arrays. This includes inferring ethnicity/ancestry, gestational age, and cell composition from placental DNA methylation array (450k/850k) data.

SIGHTS is a suite of normalization methods, statistical tests, and diagnostic graphical tools for high throughput screening (HTS) assays. HTS assays use microtitre plates to screen large libraries of compounds for their biological, chemical, or biochemical activity.

This is a package for semi-supervised isoform detection and annotation from both bulk and single-cell long read RNA-seq data. Flames provides automated pipelines for analysing isoforms, as well as intermediate functions for manual execution.

This package provides an API for efficient .hic file data extraction with programmatic matrix access. It doesn't store the pointer data for all the matrices, only the one queried, and currently it only supports matrices.

Seamless extraction of river networks from digital elevation models data. The package allows analysis of digital elevation models that can be either externally provided or downloaded from open source repositories (thus interfacing with the elevatr package). Extraction is performed via the D8 flow direction algorithm of TauDEM (Terrain Analysis Using Digital Elevation Models), thus interfacing with the traudem package. Resulting river networks are compatible with functions from the OCNet package. See Carraro (2023) <doi:10.5194/hess-27-3733-2023> for a presentation of the package.

The open sourced data management software Integrated Rule-Oriented Data System ('iRODS') offers solutions for the whole data life cycle (<https://irods.org/>). The loosely constructed and highly configurable architecture of iRODS frees the user from strict formatting constraints and single-vendor solutions. This package provides an interface to the iRODS HTTP API, allowing you to manage your data and metadata in iRODS with R. Storage of annotated files and R objects in iRODS ensures findability, accessibility, interoperability, and reusability of data.

Continuous smoothing of probability density function on a compact or semi-infinite support is performed using four continuous associated kernels: extended beta, gamma, lognormal and reciprocal inverse Gaussian. The cross-validation technique is also implemented for bandwidth selection.

Estimation of one- and two-sided confidence intervals via the numerical inversion of the cumulative distribution function of a statistic's sampling distribution. For more details, see section 9.2.3 of Casella and Berger (2002) <ISBN:0534243126>.

Encrypts and decrypts using basic ciphers. None of these should be used in place of real encryption using state of the art tools. The ciphers included use methods described in the ciphers's Wikipedia and cryptography hobby websites.

The load estimation method is based on a general factor model to solve the estimates of load and specific variance. The philosophy of the package is described in Guangbao Guo. (2022). <doi:10.1007/s00180-022-01270-z>.

This package provides a set of functions for securely storing API tokens and interacting with the <https://diariodeobras.net> system. Includes convenient wrappers around the httr2 package to perform authenticated requests, retrieve project details, tasks, reports, and more.

Detect abrupt changes in time series with local fluctuations as a random walk process and autocorrelated noise as an AR(1) process. See Romano, G., Rigaill, G., Runge, V., Fearnhead, P. (2021) <doi:10.1080/01621459.2021.1909598>.

Detection of differential item functioning (DIF) among dichotomously scored items and differential distractor functioning (DDF) among unscored items with non-linear regression procedures based on generalized logistic regression models (Hladka & Martinkova, 2020, <doi:10.32614/RJ-2020-014>).

This package provides a rich toolkit of using the whole building simulation program EnergyPlus'(<https://energyplus.net>), which enables programmatic navigation, modification of EnergyPlus models and makes it less painful to do parametric simulations and analysis.

This package provides a flexible interface to the Financial Modeling Prep API <https://site.financialmodelingprep.com/developer/docs>. The package supports all available endpoints and parameters, enabling R users to interact with a wide range of financial data.

Genealogical data analysis including descriptive statistics (e.g., kinship and inbreeding coefficients) and gene-dropping simulations. See: "GENLIB: an R package for the analysis of genealogical data" Gauvin et al. (2015) <doi:10.1186/s12859-015-0581-5>.