This package provides a program to generate smoothed quantiles for the Fst-heterozygosity distribution. Designed for use with large numbers of loci (e.g., genome-wide SNPs). The best case for analyzing the Fst-heterozygosity distribution is when many populations (>10) have been sampled. See Flanagan & Jones (2017) <doi:10.1093/jhered/esx048>.

Extremely efficient procedures for fitting regularization path with l0, l1, and truncated lasso penalty for linear regression and logistic regression models. This version is a completely new version compared with our previous version, which was mainly based on R. New core algorithms are developed and are now written in C++ and highly optimized.

Gene and Region Counting of Mutations (GARCOM) package computes mutation (or alleles) counts per gene per individuals based on gene annotation or genomic base pair boundaries. It comes with features to accept data formats in plink(.raw) and VCF. It provides users flexibility to extract and filter individuals, mutations and genes of interest.

We provides functions that employ splines to estimate generalized partially linear single index models (GPLSIM), which extend the generalized linear models to include nonlinear effect for some predictors. Please see Y. (2017) at <doi:10.1007/s11222-016-9639-0> and Y., and R. (2002) at <doi:10.1198/016214502388618861> for more details.

The heatex package calculates heat storage in the body and the components of heat exchange (conductive, convective, radiative, and evaporative) between the body and the environment during physical activity based on the principles of partitional calorimetry. The program enables heat exchange calculations for a range of environmental conditions when wearing various clothing ensembles.

Implementation of analytical and sampling-based power analyses for the Wald, likelihood ratio (LR), score, and gradient tests. Can be applied to item response theory (IRT) models that are fitted using marginal maximum likelihood estimation. The methods are described in our paper (Zimmer et al. (2022) <doi:10.1007/s11336-022-09883-5>).

It uses species accumulation curves and diverse estimators to assess, at the same time, the levels of survey coverage in multiple geographic cells of a size defined by the user or polygons. It also enables the geographical depiction of observed species richness, survey effort and completeness values including a background with administrative areas.

Parse various reflectance/transmittance/absorbance spectra file formats to extract spectral data and metadata, as described in Gruson, White & Maia (2019) <doi:10.21105/joss.01857>. Among other formats, it can import files from Avantes <https://www.avantes.com/>, CRAIC <https://www.microspectra.com/>, and OceanOptics'/'OceanInsight <https://www.oceanoptics.com/> brands.

This is a companion to the book Cook, D. and Laa, U. (2023) <https://dicook.github.io/mulgar_book/> "Interactively exploring high-dimensional data and models in R". by Cook and Laa. It contains useful functions for processing data in preparation for visualising with a tour. There are also several sample data sets.

Omics data come in different forms: gene expression, methylation, copy number, protein measurements and more. NCutYX allows clustering of variables, of samples, and both variables and samples (biclustering), while incorporating the dependencies across multiple types of Omics data. (SJ Teran Hidalgo et al (2017), <doi:10.1186/s12864-017-3990-1>).

This package implements the PRIDIT (Principal Component Analysis applied to RIDITs') scoring system described in Brockett et al. (2002) <doi:10.1111/1539-6975.00027>. Provides functions for ridit scoring originally developed by Bross (1958) <doi:10.2307/2527727>, calculating PRIDIT weights, and computing final PRIDIT scores for multivariate analysis of ordinal data.

Enforces good practice and provides convenience functions to make work with JavaScript not just easier but also scalable. It is a robust wrapper to NPM', yarn', and webpack that enables to compartmentalize JavaScript code, leverage NPM and yarn packages, include TypeScript', React', or Vue in web applications, and much more.

To construct a model in 2-D space from 2-D nonlinear dimension reduction data and then lift it to the high-dimensional space. Additionally, provides tools to visualise the model overlay the data in 2-D and high-dimensional space. Furthermore, provides summaries and diagnostics to evaluate the nonlinear dimension reduction layout.

Substitution matrices are important parameters in protein alignment algorithms. These matrices represent the likelihood that an amino acid will be substituted for another during mutation. This tool allows users to apply predefined and custom matrices and then explore the resulting alignments with interactive visualizations. SubVis requires the availability of a web browser.

This package provides easy to use functions to create all-sky grid plots of widely used astronomical coordinate systems (equatorial, ecliptic, galactic) and scatter plots of data on any of these systems including on-the-fly system conversion. It supports any type of spherical projection to the plane defined by the mapproj package.

Assigns a score projection from 0 to 1 between a given in vivo stage and each single cluster from an in vitro dataset. The score is assigned based on the the fraction of specific markers of the in vivo stage that are conserved in the in vitro clusters <https://github.com/ScialdoneLab>.

Linear mixed models for complex survey data, by pairwise composite likelihood, as described in Lumley & Huang (2023) <arXiv:2311.13048>. Supports nested and crossed random effects, and correlated random effects as in genetic models. Allows for multistage sampling and for other designs where pairwise sampling probabilities are specified or can be calculated.

This program calculates bioclimatic indices and fluxes (radiation, evapotranspiration, soil moisture) for use in studies of ecosystem function, species distribution, and vegetation dynamics under changing climate scenarios. Predictions are based on a minimum of required inputs: latitude, precipitation, air temperature, and cloudiness. Davis et al. (2017) <doi:10.5194/gmd-10-689-2017>.

Fit of a double additive cure survival model with time-varying covariates. The additive terms in the long- and short-term survival submodels, modelling the cure probability and the event timing for susceptible units, are estimated using Laplace P-splines. For more details, see Lambert and Kreyenfeld (2025) <doi:10.1093/jrsssa/qnaf035>.

Computes the random forest variable importance (VIMP) for the conditional inference random forest (cforest) of the party package. Includes a function (varImp) that computes the VIMP for arbitrary measures from the measures package. For calculating the VIMP regarding the measures accuracy and AUC two extra functions exist (varImpACC and varImpAUC).

This package creates interactive web maps using the JavaScript Leaflet library with base layers of The National Map ('TNM'). TNM services provide access to base geospatial information that describes the landscape of the United States and its territories. This package is dependent on, and intended to be used with, the leaflet package.

This package provides functions for determining the effect of data weights on the variance of survey data: users will load a data set which has a weights column, and the package will calculate the design effect (DEFF), weighting loss, root design effect (DEFT), effective sample size (ESS), and/or weighted margin of error.

This package provides functionality to run a number of tasks in the differential expression analysis workflow. This encompasses the most widely used steps, from running various enrichment analysis tools with a unified interface to creating plots and beautifying table components linking to external websites and databases. This streamlines the generation of comprehensive analysis reports.

This package provides functions to compare two or more survival curves with:

• The Fleming-Harrington test for right-censored data based on permutations and on counting processes.

• An extension of the Fleming-Harrington test for interval-censored data based on a permutation distribution and on a score vector distribution.