This package provides a simple interface to search available data provided by Theia (<https://theia.cnes.fr>), download it, and manage it. Data can be downloaded based on a search result or from a cart file downloaded from Theia website.

This package provides fast access to many commonly used taxonomic authorities in a uniform Darwin Core format. Tables are read directly from versioned Parquet snapshots, streamed from cloud storage or from a local copy, and queried with familiar dplyr verbs.

This package implements differential language analysis with statistical tests and offers various language visualization techniques for n-grams and topics. It also supports the text package. For more information, visit <https://r-topics.org/> and <https://www.r-text.org/>.

Simulation, exploratory data analysis and Bayesian analysis of the p-order Integer-valued Autoregressive (INAR(p)) and Zero-inflated p-order Integer-valued Autoregressive (ZINAR(p)) processes, as described in Garay et al. (2020) <doi:10.1080/00949655.2020.1754819>.

Doubly ranked tests are nonparametric tests for grouped functional and multivariate data. The testing procedure first ranks a matrix (or three dimensional array) of data by column (if a matrix) or by cell (across the third dimension if an array). By default, it calculates a sufficient statistic for the subject's order within the sample using the observed ranks, taken over the columns or cells. Depending on the number of groups, G, the summarized ranks are then analyzed using either a Wilcoxon Rank Sum test (G = 2) or a Kruskal-Wallis (G greater than 2).

Restricted Cubic Splines were performed to explore the shape of association form of "U, inverted U, L" shape and test linearity or non-linearity base on "Cox,Logistic,linear,quasipoisson" regression, and auto output Restricted Cubic Splines figures. rcssci package could automatically draw RCS graphics with Y-axis "OR,HR,RR,beta". The Restricted Cubic Splines method were based on Suli Huang (2022) <doi:10.1016/j.ecoenv.2022.113183>,Amit Kaura (2019) <doi:10.1136/bmj.l6055>, and Harrell Jr (2015, ISBN:978-3-319-19424-0 (Print) 978-3-319-19425-7 (Online)).

Transform coordinates from a specified source to a specified target map projection. This uses the PROJ library directly, via the PROJ package. The reproj() function is generic, methods may be added to remove the need for an explicit source definition. This is for use primarily to transform generic data formats and direct leverage of the underlying PROJ library. (There are transformations that aren't possible with PROJ and that are provided by the GDAL library, a limitation which users of this package should be aware of.) The PROJ library is available at <https://proj.org/>.

This package implements the interim augmented inverse probability weighted estimator (IAIPWE) for estimating the value of treatment regimes embedded in sequential multiple assignment randomized trials (SMARTs). The IAIPWE subsumes both the inverse probability weighted estimator (IPWE) and the augmented inverse probability weighted estimator (AIPWE), enabling inference at interim and final analyses. The package provides functions for value estimation, sandwich variance computation, group sequential stopping boundaries, and sample size determination for multi-stage SMARTs with up to two treatment options at each stage. See Manschot, Laber, and Davidian (2023) <doi:10.1111/biom.13854> for additional details.

This package provides a framework for the analysis and exploration of single-cell chromatin data. The Signac package contains functions for quantifying single-cell chromatin data, computing per-cell quality control metrics, dimension reduction and normalization, visualization, and DNA sequence motif analysis.

This package provides Principal Components Analysis (PCA) of matrix using Non-linear Iterative Partial Least Squares (NIPALS) or weighted Expectation Maximization PCA (EMPCA) with Gram-Schmidt orthogonalization of the scores and loadings. See Andrecut (2009) doi:10.1089/cmb.2008.0221.

This package provides type-stable rolling window functions over any R data type. Cumulative and expanding windows are also supported. For more advanced usage, an index can be used as a secondary vector that defines how sliding windows are to be created.

Design primers for targeted single-cell RNA-seq used by TAP-seq. Create sequence templates for target gene panels and design gene-specific primers using Primer3. Potential off-targets can be estimated with BLAST. Requires working installations of Primer3 and BLASTn.

This package provides a structured S4 approach to importing data files from the 10X pipelines. It mainly supports Single Cell Multiome ATAC + Gene Expression data among other data types. The main Bioconductor data representations used are SingleCellExperiment and RaggedExperiment.

Lightweight validation tool for checking function arguments and validating data analysis scripts. This is an alternative to stopifnot() from the base package and to assert_that() from the assertthat package. It provides more informative error messages and facilitates debugging.

Causal discovery in linear structural equation models (Schultheiss, and Bühlmann (2023) <doi:10.1093/biomet/asad008>) and vector autoregressive models (Schultheiss, Ulmer, and Bühlmann (2025) <doi:10.1515/jci-2024-0011>) with explicit error control for false discovery, at least asymptotically.

This package provides WHO Child Growth Standards (z-scores) with confidence intervals and standard errors around the prevalence estimates, taking into account complex sample designs. More information on the methods is available online: <https://www.who.int/tools/child-growth-standards>.

Dose-response modeling for negative-binomial distributed data with a variety of dose-response models. Covariate adjustment and Bayesian model averaging is supported. Functions are provided to easily obtain inference on the dose-response relationship and plot the dose-response curve.

This package contains a number of functions for different business sample coordination algorithms together with a function to generate customizable business data sets. For more details see Straubinger (2025) <https://ubt.opus.hbz-nrw.de/frontdoor/index/index/docId/2785>.

This package provides functions to produce some circular plots for circular data, in a height- or area-proportional manner. They include bar plots, smooth density plots, stacked dot plots, histograms, multi-class stacked smooth density plots, and multi-class stacked histograms.

This package provides a clustered random forest algorithm for fitting random forests for data of independent clusters, that exhibit within cluster dependence. Details of the method can be found in Young and Buehlmann (2025) <doi:10.48550/arXiv.2503.12634>.

This package provides functions for nonlinear regression parameters estimation by algorithms based on Controlled Random Search algorithm. Both functions (crs4hc(), crs4hce()) adapt current search strategy by four heuristics competition. In addition, crs4hce() improves adaptability by adaptive stopping condition.

Differential Analysis of short RNA transcripts that can be modeled by either Poisson or Negative binomial distribution. The statistical methodology implemented in this package is based on the random selection of references genes (Desaulle et al. (2021) <arXiv:2103.09872>).

Simplifies and automates the process of exploring and merging data from relational databases. This package allows users to discover table relationships, create a map of all possible joins, and generate executable plans to merge data based on a structured metadata framework.

Load polar volume and vertical profile data for aeroecological research directly into R. With getRad you can access data from several sources in Europe and the US and standardize it to facilitate further exploration in tools such as bioRad'.