This package contains methods for calculating Interaction Based Homogeneity to evaluate fitness of gene lists to an interaction network which is useful for evaluation of clustering results and gene list analysis. BioGRID interactions are used in the calculation. The user can also provide their own interactions.

The mia package implements tools for microbiome analysis based on the SummarizedExperiment, SingleCellExperiment and TreeSummarizedExperiment infrastructure. Data wrangling and analysis in the context of taxonomic data is the main scope. Additional functions for common task are implemented such as community indices calculation and summarization.

RSeQC provides a number of modules that can comprehensively evaluate high throughput sequence data, especially RNA-seq data. Some basic modules inspect sequence quality, nucleotide composition bias, PCR bias and GC bias, while RNA-seq specific modules evaluate sequencing saturation, mapped reads distribution, coverage uniformity, strand specificity, etc.

This package offers a flexible, feature-rich yet light-weight logging framework based on R6 classes. It supports hierarchical loggers, custom log levels, arbitrary data fields in log events, logging to plaintext, JSON, (rotating) files, memory buffers, and databases, as well as email and push notifications.

This is a package for ratios of count data such as obtained from RNA-seq are modelled using Bayesian statistics to derive posteriors for effects sizes. This approach is described in Erhard & Zimmer (2015) <doi:10.1093/nar/gkv696> and Erhard (2018) <doi:10.1093/bioinformatics/bty471>.

RHash is a console utility for calculation and verification of magnet links and a wide range of hash sums like CRC32, MD4, MD5, SHA1, SHA256, SHA512, SHA3, AICH, ED2K, Tiger, DC++ TTH, BitTorrent BTIH, GOST R 34.11-94, RIPEMD-160, HAS-160, EDON-R, Whirlpool and Snefru.

This package implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis. Such an interim analysis can either be blinded or unblinded. Code is provided for Normally distributed endpoints with known variance, with a prominent example being the hazard ratio.

Reading and writing of files in the most commonly used formats of structural crystallography. It includes functions to work with a variety of statistics used in this field and functions to perform basic crystallographic computing. References: D. G. Waterman, J. Foadi, G. Evans (2011) <doi:10.1107/S0108767311084303>.

Calculate mean statistics and leaf angle distribution type from measured leaf inclination angles. LAD distribution is fitted using a two-parameters (mu, nu) Beta distribution and compared with six theoretical LAD distributions. Additional information is provided in Chianucci and Cesaretti (2022) <doi:10.1101/2022.10.28.513998>.

This package contains the Markov cluster algorithm (MCL) for identifying clusters in networks and graphs. The algorithm simulates random walks on a (n x n) matrix as the adjacency matrix of a graph. It alternates an expansion step and an inflation step until an equilibrium state is reached.

An aggressive dimensionality reduction and network estimation technique for a high-dimensional Gaussian graphical model (GGM). Please refer to: Efficient Dimensionality Reduction for High-Dimensional Network Estimation, Safiye Celik, Benjamin A. Logsdon, Su-In Lee, Proceedings of The 31st International Conference on Machine Learning, 2014, p. 1953--1961.

Fits non-homogeneous Markov multistate models and misclassification-type hidden Markov models in continuous time to intermittently observed data. Implements the methods in Titman (2011) <doi:10.1111/j.1541-0420.2010.01550.x>. Uses direct numerical solution of the Kolmogorov forward equations to calculate the transition probabilities.

This package implements a novel predictive model, Partially Interpretable Estimators (PIE), which jointly trains an interpretable model and a black-box model to achieve high predictive performance as well as partial model. See the paper, Wang, Yang, Li, and Wang (2021) <doi:10.48550/arXiv.2105.02410>.

The package solves linear system of equations Ax=b by using Preconditioned Conjugate Gradient Algorithm where A is real symmetric positive definite matrix. A suitable preconditioner matrix may be provided by user. This can also be used to minimize quadratic function (x'Ax)/2-bx for unknown x.

This package provides different specifications of a Quadrilateral Dissimilarity Model which can be used to fit same-different judgments in order to get a predicted matrix that satisfies regular minimality [Colonius & Dzhafarov, 2006, Measurement and representations of sensations, Erlbaum]. From such a matrix, Fechnerian distances can be computed.

The skew logistic distribution is a quantile-defined generalisation of the logistic distribution (van Staden and King 2015). Provides random numbers, quantiles, probabilities, densities and density quantiles for the distribution. It provides Quantile-Quantile plots and method of L-Moments estimation (including asymptotic standard errors) for the distribution.

The X13-ARIMA-SEATS <https://www.census.gov/data/software/x13as.html> methodology and software is a widely used software and developed by the US Census Bureau. It can be accessed from R with this package and X13-ARIMA-SEATS binaries are provided by the R package x13binary'.

This package provides bitmapped vectors of booleans (no NAs), coercion from and to logicals, integers and integer subscripts, fast boolean operators and fast summary statistics. With bit class vectors of true binary booleans, TRUE and FALSE can be stored with 1 bit only.

This package provides tools for the analysis of growth data: to extract an LMS table from a gamlss object, to calculate the standard deviation scores and its inverse, and to superpose two wormplots from different models. The package contains a some varieties of reference tables, especially for The Netherlands.

Causal Inference Assistance (CIA) for performing causal inference within the structural causal modelling framework. Structure learning is performed using partition Markov chain Monte Carlo (Kuipers & Moffa, 2017) and several additional functions have been added to help with causal inference. Kuipers and Moffa (2017) <doi:10.1080/01621459.2015.1133426>.

The state-of-the-art algorithms for distance metric learning, including global and local methods such as Relevant Component Analysis, Discriminative Component Analysis, Local Fisher Discriminant Analysis, etc. These distance metric learning methods are widely applied in feature extraction, dimensionality reduction, clustering, classification, information retrieval, and computer vision problems.

This package provides a consistent tool for downloading ECH data, processing them and generating new indicators: poverty, education, employment, etc. All data are downloaded from the official site of the National Institute of Statistics at <https://www.gub.uy/instituto-nacional-estadistica/datos-y-estadisticas/encuestas/encuesta-continua-hogares>.

Forest data quality is a package containing nine methods of analysis for forest databases, from databases containing inventory data and growth models, the focus of the analyzes is related to the quality of the data present in the database with a focus on consistency , punctuality and completeness of data.

Simplifies the process of importing and managing input-output matrices from Microsoft Excel into R, and provides a suite of functions for analysis. It leverages the R6 class for clean, memory-efficient object-oriented programming. Furthermore, all linear algebra computations are implemented in Rust to achieve highly optimized performance.