Fit of a double additive cure survival model with time-varying covariates. The additive terms in the long- and short-term survival submodels, modelling the cure probability and the event timing for susceptible units, are estimated using Laplace P-splines. For more details, see Lambert and Kreyenfeld (2025) <doi:10.1093/jrsssa/qnaf035>.

Computes the random forest variable importance (VIMP) for the conditional inference random forest (cforest) of the party package. Includes a function (varImp) that computes the VIMP for arbitrary measures from the measures package. For calculating the VIMP regarding the measures accuracy and AUC two extra functions exist (varImpACC and varImpAUC).

This package creates interactive web maps using the JavaScript Leaflet library with base layers of The National Map ('TNM'). TNM services provide access to base geospatial information that describes the landscape of the United States and its territories. This package is dependent on, and intended to be used with, the leaflet package.

This package provides functions for determining the effect of data weights on the variance of survey data: users will load a data set which has a weights column, and the package will calculate the design effect (DEFF), weighting loss, root design effect (DEFT), effective sample size (ESS), and/or weighted margin of error.

This package provides a toolkit for analyzing classifier performance by using receiver operating characteristic (ROC) curves. Performance may be assessed on a single classifier or multiple ones simultaneously, making it suitable for comparisons. In addition, different metrics allow the evaluation of local performance when working within restricted ranges of sensitivity and specificity. For details on the different implementations, see McClish D. K. (1989) <doi:10.1177/0272989X8900900307>, Vivo J.-M., Franco M. and Vicari D. (2018) <doi:10.1007/S11634-017-0295-9>, Jiang Y., et al (1996) <doi:10.1148/radiology.201.3.8939225>, Franco M. and Vivo J.-M. (2021) <doi:10.3390/math9212826> and Carrington, André M., et al (2020) <doi: 10.1186/s12911-019-1014-6>.

Transform coordinates from a specified source to a specified target map projection. This uses the PROJ library directly, by wrapping the PROJ package which leverages libproj', otherwise the proj4 package. The reproj() function is generic, methods may be added to remove the need for an explicit source definition. If proj4 is in use reproj() handles the requirement for conversion of angular units where necessary. This is for use primarily to transform generic data formats and direct leverage of the underlying PROJ library. (There are transformations that aren't possible with PROJ and that are provided by the GDAL library, a limitation which users of this package should be aware of.) The PROJ library is available at <https://proj.org/>.

Algorithms for the spatial stratification of landscapes, sampling and modeling of spatially-varying phenomena. These algorithms offer a simple framework for the stratification of geographic space based on raster layers representing landscape factors and/or factor scales. The stratification process follows a hierarchical approach, which is based on first level units (i.e., classification units) and second-level units (i.e., stratification units). Nonparametric techniques allow to measure the correspondence between the geographic space and the landscape configuration represented by the units. These correspondence metrics are useful to define sampling schemes and to model the spatial variability of environmental phenomena. The theoretical background of the algorithms and code examples are presented in Fuentes et al. (2022). <doi:10.32614/RJ-2022-036>.

This package annmap provides annotation mappings for Affymetrix exon arrays and coordinate based queries to support deep sequencing data analysis. Database access is hidden behind the API which provides a set of functions such as genesInRange(), geneToExon(), exonDetails(), etc. Functions to plot gene architecture and BAM file data are also provided.

This package provides functions for fitting the generalized additive models for location scale and shape introduced by Rigby and Stasinopoulos (2005), doi:10.1111/j.1467-9876.2005.00510.x. The models use a distributional regression approach where all the parameters of the conditional distribution of the response variable are modelled using explanatory variables.

This package estimates tumor purity, copy number, and loss of heterozygosity (LOH), and classifies single nucleotide variants (SNVs) by somatic status and clonality. PureCN is designed for targeted short read sequencing data, integrates well with standard somatic variant detection and copy number pipelines, and has support for tumor samples without matching normal samples.

This package provides a pipeline which processes single cell RNA-seq (scRNA-seq) reads from CEL-seq and CEL-seq2 protocols. Demultiplex scRNA-seq FASTQ files, align reads to reference genome using Rsubread, and generate UMI filtered count matrix. Also provide visualizations of read alignments and pre- and post-alignment QC metrics.

This package serves as an upstream pipeline for pre-processing sequencing-based spatial transcriptomics data. Functions includes FASTQ trimming, BAM file reformatting, index building, spatial barcode detection, demultiplexing, gene count matrix generation with UMI deduplication, QC, and revelant visualization. Config is an essential input for most of the functions which aims to improve reproducibility.

This package provides a suite of functions for simulating spatial patterns of cells in tissue images. Output images are multitype point data in SingleCellExperiment format. Each point represents a cell, with its 2D locations and cell type. Potential cell patterns include background cells, tumour/immune cell clusters, immune rings, and blood/lymphatic vessels.

Simulates, fits, and predicts long-memory and anti-persistent time series, possibly mixed with ARMA, regression, transfer-function components. Exact methods (MLE, forecasting, simulation) are used. Bug reports should be done via GitHub (at <https://github.com/JQVeenstra/arfima>), where the development version of this package lives; it can be installed using devtools.

This package provides functions for exploring and visualising estimation results obtained with BayesX, a free software for estimating structured additive regression models (<https://www.uni-goettingen.de/de/bayesx/550513.html>). In addition, functions that allow to read, write and manipulate map objects that are required in spatial analyses performed with BayesX.

Estimation, prediction, and simulation of nonstationary Gaussian process with modular covariate-based covariance functions. Sources of nonstationarity, such as spatial mean, variance, geometric anisotropy, smoothness, and nugget, can be considered based on spatial characteristics. An induced compact-supported nonstationary covariance function is provided, enabling fast and memory-efficient computations when handling densely sampled domains.

This package provides a spatially-aware cell clustering algorithm is provided with cluster significance assessment. It comprises four key modules: spatially-aware cell-gene co-embedding, cell clustering, signature gene identification, and cluster significant assessment. More details can be referred to Peng Xie, et al. (2025) <doi:10.1016/j.cell.2025.05.035>.

Many modern C/C++ development tools in the clang toolchain, such as clang-tidy or clangd', rely on the presence of a compilation database in JSON format <https://clang.llvm.org/docs/JSONCompilationDatabase.html>. This package temporarily injects additional build flags into the R build process to generate such a compilation database.

Draws stylized choropleth maps -- hexagonal maps and triangular multiclass hex maps -- for New Zealand District Health Boards and Regional Council areas. These allow faceted, coloured displays of quantitative information for comparison across District Health Boards or Regional Councils. The preprint Lumley (2019) <arXiv:1912.04435> is based on the methods in this package.

Populate data from an R environment into .doc and .docx templates. Create a template document in a program such as Word', and add strings encased in guillemet characters to create flags («example»). Use getDictionary() to create a dictionary of flags and replacement values, then call docket() to generate a populated document.

This package provides tools for simulating draws from continuous time processes with well-defined exponential family random graph (ERGM) equilibria, i.e. ERGM generating processes (EGPs). A number of EGPs are supported, including the families identified in Butts (2023) <doi:10.1080/0022250X.2023.2180001>, as are functions for hazard calculation and timing calibration.

The Explainable Ensemble Trees e2tree approach has been proposed by Aria et al. (2024) <doi:10.1007/s00180-022-01312-6>. It aims to explain and interpret decision tree ensemble models using a single tree-like structure. e2tree is a new way of explaining an ensemble tree trained through randomForest or xgboost packages.

Estimate gender from names in Spanish and Portuguese. Works with vectors and dataframes. The estimation works not only for first names but also full names. The package relies on a compilation of common names with it's most frequent associated gender in both languages which are used as look up tables for gender inference.

This package provides an interface to HDFql <https://www.hdfql.com/> and helper functions for reading data from and writing data to HDF5 files. HDFql provides a high-level language for managing HDF5 data that is platform independent. For more information, see the reference manual <https://www.hdfql.com/resources/HDFqlReferenceManual.pdf>.