The Shaman package implements functions for resampling Hi-C matrices in order to generate expected contact distributions given constraints on marginal coverage and contact-distance probability distributions. The package also provides support for visualizing normalized matrices and statistical analysis of contact distributions around selected landmarks.
This package provides tools for the analysis of high-dimensional data developed/implemented at the group "Statistical Complexity Reduction In Molecular Epidemiology" (SCRIME). The main focus is on SNP data, but most of the functions can also be applied to other types of categorical data.
The httpuv package provides low-level socket and protocol support for handling HTTP and WebSocket requests directly from within R. It is primarily intended as a building block for other packages, rather than making it particularly easy to create complete web applications using httpuv alone.
This package provides an implementation of both the exact and approximation methods for computing the cumulative distribution function (CDF) of the Poisson binomial distribution. It also provides the probability mass function (PMF), quantile function, and random number generation for the Poisson binomial distribution.
The glmnet package provides efficient procedures for fitting the entire lasso or elastic-net regularization path for linear and Poisson regression, as well as logistic, multinomial, Cox, multiple-response Gaussian and grouped multinomial models. The algorithm uses cyclical coordinate descent in a path-wise fashion.
This package contains functions for reading raw data in ImaGene TXT format obtained from Exiqon miRCURY LNA arrays, annotating them with appropriate GAL files, and normalizing them using a spike-in probe-based method. Other platforms and data formats are also supported.
This package provides a client to simplify fetching predictions from the Koina web service. Koina is a model repository enabling the remote execution of models. Predictions are generated as a response to HTTP/S requests, the standard protocol used for nearly all web traffic.
There are increasing demands on designing virus mutants with specific dinucleotide or codon composition. This tool can take both dinucleotide preference and/or codon usage bias into account while designing mutants. It is a powerful tool for in silico designs of DNA sequence mutants.
An unsupervised cross-validation method to select the optimal number of mutational signatures. A data set of mutational counts is split into training and validation data.Signatures are estimated in the training data and then used to predict the mutations in the validation data.
The tools in this package are intended to help researchers assess multiple treatment-covariate interactions with data from a parallel-group randomized controlled clinical trial. The methods implemented in the package were proposed in Kovalchik, Varadhan and Weiss (2013) <doi: 10.1002/sim.5881>.
Extract, visualize and summarize aerial movements of birds and insects from weather radar data. See Dokter, A. M. et al. (2018) "bioRad: biological analysis and visualization of weather radar data" <doi:10.1111/ecog.04028> for a software paper describing package and methodologies.
This package provides functions to perform Bayesian nonparametric univariate and multivariate density estimation and clustering, by means of Pitman-Yor mixtures, and dependent Dirichlet process mixtures for partially exchangeable data. See Corradin et al. (2021) <doi:10.18637/jss.v100.i15> for more details.
This package implements bidirectional two-stage least squares (Bi-TSLS) estimation for identifying bidirectional causal effects between two variables in the presence of unmeasured confounding. The method uses proxy variables (negative control exposure and outcome) along with at least one covariate to handle confounding.
An implementation of Jon Kleinberg's burst detection algorithm (Kleinberg (2003) <doi:10.1023/A:1024940629314>). Uses an infinite Markov model to detect periods of increased activity in a series of discrete events with known times, and provides a simple visualization of the results.
This package provides data import and offers 3 daily snapshot functions from securities of varying prices traded on the Bolivian Securities Exchange, website <https://www.bbv.com.bo/>. The snapshots include a detailed list, scatter plot correlation, and descriptive statistics table for the securities.
This package provides methods for interpretable machine learning with an emphasis on local feature importance estimation. The package implements the CLIQUE framework for computing observation-level importance values. Additional tools are included for visualizing multi-class partial dependence relationships across predictors and response classes.
This package provides an alternative approach to multiple testing by calculating a simultaneous upper confidence bounds for the number of true null hypotheses among any subset of the hypotheses of interest, using the methods of Goeman and Solari (2011) <doi:10.1214/11-STS356>.
This package provides functions for comparing two data.frames against each other. The core functionality is to provide a detailed breakdown of any differences between two data.frames as well as providing utility functions to help narrow down the source of problems and differences.
In order to provide unified access to Linux distribution details in R, this package wraps the various files and commands that may exist on a system. It is similar in spirit to the lsb_release command and the Python package of the same name.
Computes and plots a transformed empirical CDF (ecdf) as a diagnostic for heavy tailed data, specifically data with power law decay on the tails. Routines for annotating the plot, comparing data to a model, fitting a nonparametric model, and some multivariate extensions are given.
Functional principal component analysis under the Linear Mixed Models representation of smoothing splines. The method utilizes the Demmler-Reinsch basis and assumes error independence. For more details see: F. Rosales (2016) <https://ediss.uni-goettingen.de/handle/11858/00-1735-0000-0028-87F9-6>.
Fuzzy clustering of species in an ecological community as common or rare based on their abundance and occupancy. It also includes functions to compute confidence intervals of classification metrics and plot results. See Balbuena et al. (2020, <doi:10.1101/2020.08.12.247502>).
Companion package for the manual guide-R : Guide pour lâ analyse de données dâ enquêtes avec R available at <https://larmarange.github.io/guide-R/>. guideR implements miscellaneous functions introduced in guide-R to facilitate statistical analysis and manipulation of survey data.
Enhance a mice imputation workflow with visualizations for incomplete and/or imputed data. The plotting functions produce ggplot objects which may be easily manipulated or extended. Use ggmice to inspect missing data, develop imputation models, evaluate algorithmic convergence, or compare observed versus imputed data.