MEIGOR provides a comprehensive environment for performing global optimization tasks in bioinformatics and systems biology. It leverages advanced metaheuristic algorithms to efficiently search the solution space and is specifically tailored to handle the complexity and high-dimensionality of biological datasets. This package supports various optimization routines and is integrated with Bioconductor's infrastructure for a seamless analysis workflow.

An R package for multiple-group comparison to detect tissue/cell-specific marker genes among subtypes. It provides functions to compute OVESEG-test statistics, derive component weights in the mixture null distribution model and estimate p-values from weightedly aggregated permutations. Obtained posterior probabilities of component null hypotheses can also portrait all kinds of upregulation patterns among subtypes.

Implementation of the technique of Lleonart et al. (2000) <doi:10.1006/jtbi.2000.2043> to scale body measurements that exhibit an allometric growth. This procedure is a theoretical generalization of the technique used by Thorpe (1975) <doi:10.1111/j.1095-8312.1975.tb00732.x> and Thorpe (1976) <doi:10.1111/j.1469-185X.1976.tb01063.x>.

Typically, models in R exist in memory and can be saved via regular R serialization. However, some models store information in locations that cannot be saved using R serialization alone. The goal of bundle is to provide a common interface to capture this information, situate it within a portable object, and restore it for use in new settings.

Bayesian analysis of luminescence data and C-14 age estimates. Bayesian models are based on the following publications: Combes, B. & Philippe, A. (2017) <doi:10.1016/j.quageo.2017.02.003> and Combes et al. (2015) <doi:10.1016/j.quageo.2015.04.001>. This includes, amongst others, data import, export, application of age models and palaeodose model.

The Crunch.io service <https://crunch.io/> provides a cloud-based data store and analytic engine, as well as an intuitive web interface. Using this package, analysts can interact with and manipulate Crunch datasets from within R. Importantly, this allows technical researchers to collaborate naturally with team members, managers, and clients who prefer a point-and-click interface.

Convert text into synthesized speech and get a list of supported voices for a region. Microsoft's Cognitive Services Text to Speech REST API <https://learn.microsoft.com/en-us/azure/cognitive-services/speech-service/rest-text-to-speech?tabs=streaming> supports neural text to speech voices, which support specific languages and dialects that are identified by locale.

Allows humanitarian community, academia, media, government, and non-governmental organizations to utilize the data collected by the Displacement Tracking Matrix (<https://dtm.iom.int>), a unit in the International Organization for Migration. This also provides non-sensitive Internally Displaced Person figures, aggregated at the country, Admin 1 (states, provinces, or equivalent), and Admin 2 (smaller administrative areas) levels.

Allows to perform the dynamic mixture estimation with state-space components and normal regression components, and clustering with normal mixture. Quasi-Bayesian estimation, as well as, that based on the Kerridge inaccuracy approximation are implemented. Main references: Nagy and Suzdaleva (2013) <doi:10.1016/j.apm.2013.05.038>; Nagy et al. (2011) <doi:10.1002/acs.1239>.

Tool to print out the value of R objects/expressions while running an R script. Outputs can be made dependent on user-defined conditions/criteria. Debug messages only appear when a global option for debugging is set. This way, debugr code can even remain in the debugged code for later use without any negative effects during normal runtime.

Create and customize interactive collapsible D3 trees using the D3 JavaScript library and the htmlwidgets package. These trees can be used directly from the R console, from RStudio', in Shiny apps and R Markdown documents. When in Shiny the tree layout is observed by the server and can be used as a reactive filter of structured data.

This package provides utility functions for standardizing economic entity (economy, aggregate, institution, etc.) name and id in economic datasets such as those published by the International Monetary Fund and World Bank. Aims to facilitate consistent data analysis, reporting, and joining across datasets. Used as a foundational building block in the econdataverse family of packages (<https://www.econdataverse.org>).

This package performs test procedures for general hypothesis testing problems for four multivariate coefficients of variation (Ditzhaus and Smaga, 2023 <arXiv:2301.12009>). We can verify the global hypothesis about equality as well as the particular hypotheses defined by contrasts, e.g., we can conduct post hoc tests. We also provide the simultaneous confidence intervals for contrasts.

This package provides a suite of routines for the hyperdirichlet distribution and reified Bradley-Terry; supersedes the hyperdirichlet package; uses disordR discipline <doi:10.48550/ARXIV.2210.03856>. To cite in publications please use Hankin 2017 <doi:10.32614/rj-2017-061>, and for Generalized Plackett-Luce likelihoods use Hankin 2024 <doi:10.18637/jss.v109.i08>.

This package provides functions for genome-wide association studies (GWAS)/gene-environment-wide interaction studies (GEWIS) with longitudinal outcomes and exposures. He et al. (2017) "Set-Based Tests for Gene-Environment Interaction in Longitudinal Studies" and He et al. (2017) "Rare-variant association tests in longitudinal studies, with an application to the Multi-Ethnic Study of Atherosclerosis (MESA)".

Simulation, analysis and sampling of spatial biodiversity data (May, Gerstner, McGlinn, Xiao & Chase 2017) <doi:10.1111/2041-210x.12986>. In the simulation tools user define the numbers of species and individuals, the species abundance distribution and species aggregation. Functions for analysis include species rarefaction and accumulation curves, species-area relationships and the distance decay of similarity.

Fits community site occupancy models to environmental DNA metabarcoding data collected using spatially-replicated survey design. Model fitting results can be used to evaluate and compare the effectiveness of species detection to find an efficient survey design. Reference: Fukaya et al. (2022) <doi:10.1111/2041-210X.13732>, Fukaya and Hasebe (2025) <doi:10.1002/1438-390X.12219>.

An assortment of functions that could be useful in analyzing data from psychophysical experiments. It includes functions for calculating d from several different experimental designs, links for m-alternative forced-choice (mafc) data to be used with the binomial family in glm (and possibly other contexts) and self-Start functions for estimating gamma values for CRT screen calibrations.

Useful functions and workflows for proteomics quality control and data analysis of both limited proteolysis-coupled mass spectrometry (LiP-MS) (Feng et. al. (2014) <doi:10.1038/nbt.2999>) and regular bottom-up proteomics experiments. Data generated with search tools such as Spectronaut', MaxQuant and Proteome Discover can be easily used due to flexibility of functions.

Performance metric provides different performance measures like mean squared error, root mean square error, mean absolute deviation, mean absolute percentage error etc. of a fitted model. These can provide a way for forecasters to quantitatively compare the performance of competing models. For method details see (i) Pankaj Das (2020) <http://krishi.icar.gov.in/jspui/handle/123456789/44138>.

Generates and predicts a set of linearly stacked Random Forest models using bootstrap sampling. Individual datasets may be heterogeneous (not all samples have full sets of features). Contains support for parallelization but the user should register their cores before running. This is an extension of the method found in Matlock (2018) <doi:10.1186/s12859-018-2060-2>.

This package provides functions for color-based visualization of multivariate data, i.e. colorgrams or heatmaps. Lower-level functions map numeric values to colors, display a matrix as an array of colors, and draw color keys. Higher-level plotting functions generate a bivariate histogram, a dendrogram aligned with a color-coded matrix, a triangular distance matrix, and more.

This package implements the TabNet model by Sercan O. Arik et al. (2019) <doi:10.48550/arXiv.1908.07442> with Coherent Hierarchical Multi-label Classification Networks by Giunchiglia et al. <doi:10.48550/arXiv.2010.10151> and provides a consistent interface for fitting and creating predictions. It's also fully compatible with the tidymodels ecosystem.

Unobserved components time series model using the linear innovations state space representation (single source of error) with choice of error distributions and option for dynamic variance. Methods for estimation using automatic differentiation, automatic model selection and ensembling, prediction, filtering, simulation and backtesting. Based on the model described in Hyndman et al (2012) <doi:10.1198/jasa.2011.tm09771>.