This package performs nonparametric analysis of longitudinal data in factorial experiments. Longitudinal data are those which are collected from the same subjects over time, and they frequently arise in biological sciences. Nonparametric methods do not require distributional assumptions, and are applicable to a variety of data types (continuous, discrete, purely ordinal, and dichotomous). Such methods are also robust with respect to outliers and for small sample sizes.

Estimates DNA target concentration by classifying digital PCR (polymerase chain reaction) droplets as positive, negative, or rain, using Expectation-Maximization Clustering. The fitting is accomplished using the EMMIXskew R package (v. 1.0.3) by Kui Wang, Angus Ng, and Geoff McLachlan (2018) as based on their paper "Multivariate Skew t Mixture Models: Applications to Fluorescence-Activated Cell Sorting Data" <doi:10.1109/DICTA.2009.88>.

An R API providing access to a relational database with macroeconomic time series data for South Africa, obtained from the South African Reserve Bank (SARB) and Statistics South Africa (STATSSA), and updated on a weekly basis via the EconData <https://www.econdata.co.za/> platform and automated scraping of the SARB and STATSSA websites. The database is maintained at the Department of Economics at Stellenbosch University.

Identifies what optimal subset of a desired number of items should be retained in a short version of a psychometric instrument to assess the â broadestâ proportion of the construct-level content of the set of items included in the original version of the said psychometric instrument. Expects a symmetric adjacency matrix as input (undirected weighted network model). Supports brute force and simulated annealing combinatorial search algorithms.

Estimation of group-based trajectory models, including finite mixture models for longitudinal data, supporting censored normal, zero-inflated Poisson, logit, and beta distributions, using expectation-maximization and quasi-Newton methods, with tools for model selection, diagnostics, and visualization of latent trajectory groups, <doi:10.4159/9780674041318>, Nagin, D. (2005). Group-Based Modeling of Development. Cambridge, MA: Harvard University Press. and Noel (2022), <https://orbilu.uni.lu/>, thesis.

This package provides low-level access to GDAL functionality. GDAL is the Geospatial Data Abstraction Library a translator for raster and vector geospatial data formats that presents a single raster abstract data model and single vector abstract data model to the calling application for all supported formats <https://gdal.org/>. This package is focussed on providing exactly and only what GDAL does, to enable developing further tools.

This package provides methods for detecting structural breaks and estimating break locations for linear multiple regression models under general linear restrictions on the coefficient vector. Restrictions can be within regimes, across regimes, or both, and are supported in two forms: an affine parameterization (Form A: delta = S*theta + s) and explicit linear constraints (Form B: R*delta = r). Provides break date estimation with confidence intervals, a restricted sup-F test for the null of no structural change, simulation of critical values by Monte Carlo, and a bootstrap restart procedure to reduce the risk of convergence to spurious local optima. Also implements a generalized regression tree (linear model tree) procedure where each leaf contains a linear regression model rather than a local average. Reference: Perron, P., and Qu, Z. (2006). Estimating Restricted Structural Change Models. Journal of Econometrics, 134(2), 373-399. <doi:10.1016/j.jeconom.2005.06.030>.

This package is focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.

AbSeq is a comprehensive bioinformatic pipeline for the analysis of sequencing datasets generated from antibody libraries and abseqR is one of its packages. AbseqR empowers the users of abseqPy with plotting and reporting capabilities and allows them to generate interactive HTML reports for the convenience of viewing and sharing with other researchers. Additionally, abseqR extends abseqPy to compare multiple repertoire analyses and perform further downstream analysis on its output.

This package includes functions and reference data to generate and manipulate log-ratios (also known as log size index (LSI) values) from measurements obtained on zooarchaeological material. Log ratios are used to compare the relative (rather than the absolute) dimensions of animals from archaeological contexts. The zoolog package is also able to seamlessly integrate data and references with heterogeneous nomenclature, which is internally managed by a zoolog thesaurus.

Perform seasonal adjustment and forecasting of weekly data. The package provides a user-friendly interface for computing seasonally adjusted estimates and forecasts of weekly time series and includes functions for the construction of country-specific prior adjustment variables, as well as diagnostic tools to assess the quality of the adjustments. The methodology is described in more detail in Ginker (2024) <doi:10.13140/RG.2.2.12221.44000>.

Threshold regression models are also called two-phase regression, broken-stick regression, split-point regression, structural change models, and regression kink models, with and without interaction terms. Methods for both continuous and discontinuous threshold models are included, but the support for the former is much greater. This package is described in Fong, Huang, Gilbert and Permar (2017) <DOI:10.1186/s12859-017-1863-x> and the package vignette.

Conditional distance correlation <doi:10.1080/01621459.2014.993081> is a novel conditional dependence measurement of two multivariate random variables given a confounding variable. This package provides conditional distance correlation, performs the conditional distance correlation sure independence screening procedure for ultrahigh dimensional data <https://www3.stat.sinica.edu.tw/statistica/J28N1/J28N114/J28N114.html>, and conducts conditional distance covariance test for conditional independence assumption of two multivariate variable.

This package provides a grammar of graphics approach for visualizing summary statistics from multiple Genome-wide Association Studies (GWAS). It offers geneticists, bioinformaticians, and researchers a powerful yet flexible tool for illustrating complex genetic associations using data from various GWAS datasets. The visualizations can be extensively customized, facilitating detailed comparative analysis across different genetic studies. Reference: Uffelmann, E. et al. (2021) <doi:10.1038/s43586-021-00056-9>.

This package provides a variety of functions to analyze and model geostatistical count data with Gaussian copulas, including 1) data simulation and visualization; 2) correlation structure assessment (here also known as the Normal To Anything); 3) calculate multivariate normal rectangle probabilities; 4) likelihood inference and parallel prediction at predictive locations. Description of the method is available from: Han and DeOliveira (2018) <doi:10.18637/jss.v087.i13>.

Sequential strategies for finding a game equilibrium are proposed in a black-box setting (expensive pay-off evaluations, no derivatives). The algorithm handles noiseless or noisy evaluations. Two acquisition functions are available. Graphical outputs can be generated automatically. V. Picheny, M. Binois, A. Habbal (2018) <doi:10.1007/s10898-018-0688-0>. M. Binois, V. Picheny, P. Taillandier, A. Habbal (2020) <doi:10.48550/arXiv.1902.06565>.

R function gawdis() produces multi-trait dissimilarity with more uniform contributions of different traits. de Bello et al. (2021) <doi:10.1111/2041-210X.13537> presented the approach based on minimizing the differences in the correlation between the dissimilarity of each trait, or groups of traits, and the multi-trait dissimilarity. This is done using either an analytic or a numerical solution, both available in the function.

This package provides tools for assessing and diagnosing convergence of Markov Chain Monte Carlo simulations, as well as for graphically display results from full MCMC analysis. The package also facilitates the graphical interpretation of models by providing flexible functions to plot the results against observed variables, and functions to work with hierarchical/multilevel batches of parameters (Fernández-i-Marà n, 2016 <doi:10.18637/jss.v070.i09>).

Implementation of Bayesian regressions over the meta-d model of psychological data from two alternative forced choice tasks with ordinal confidence ratings. For more information, see Maniscalco & Lau (2012) <doi:10.1016/j.concog.2011.09.021>. The package is a front-end to the brms package, which facilitates a wide range of regression designs, as well as tools for efficiently extracting posterior estimates, plotting, and significance testing.

The IntCal20 radiocarbon calibration curves (Reimer et al. 2020 <doi:10.1017/RDC.2020.68>) are provided here in a single data package, together with previous IntCal curves (IntCal13, IntCal09, IntCal04, IntCal98) and postbomb curves. Also provided are functions to copy the curves into memory, and to plot the curves and their underlying data, as well as functions to calibrate radiocarbon dates.

This package provides a set of functions to run simple and composite box-models to describe the dynamic or static distribution of stable isotopes in open or closed systems. The package also allows the sweeping of many parameters in both static and dynamic conditions. The mathematical models used in this package are derived from Albarede, 1995, Introduction to Geochemical Modelling, Cambridge University Press, Cambridge <doi:10.1017/CBO9780511622960>.

This package provides a collection of tools for interactive manipulation of (spatial) data layers on leaflet web maps. Tools include editing of existing layers, creation of new layers through drawing of shapes (points, lines, polygons), deletion of shapes as well as cutting holes into existing shapes. Provides control over options to e.g. prevent self-intersection of polygons and lines or to enable/disable snapping to align shapes.

This package provides functions that allow for convenient working with vector space models of semantics/distributional semantic models/word embeddings. Originally built for LSA models (hence the name), but can be used for all such vector-based models. For actually building a vector semantic space, use the package lsa or other specialized software. Downloadable semantic spaces can be found at <https://sites.google.com/site/fritzgntr/software-resources>.

This package provides a lasso-based method for building mechanistic models using the SAMBA algorithm (Stochastic Approximation for Model Building Algorithm) (M Prague, M Lavielle (2022) <doi:10.1002/psp4.12742>). The package extends the Rsmlx package (version 2024.1.0) to better handle high-dimensional data. It relies on the Monolix software (version 2024R1; see (<https://monolixsuite.slp-software.com/monolix/2024R1/>), which must be installed beforehand.