This package implements core utilities for single-cell RNA-seq data analysis. Contained within are utility functions for working with DE matrices and count matrices, a collection of functions for manipulating and plotting data via ggplot2, and functions to work with cell graphs and cell embeddings. Graph-based methods include embedding kNN cell graphs into a UMAP, collapsing vertices of each cluster in the graph, and propagating graph labels.

This is an alternative mechanism for importing objects from packages. The syntax allows for importing multiple objects from a package with a single command in an expressive way. The import package bridges some of the gap between using library (or require) and direct (single-object) imports. Furthermore the imported objects are not placed in the current environment. It is also possible to import objects from stand-alone .R files.

Circle Manhattan Plot is an R package that can lay out genome-wide association study P-value results in both traditional rectangular patterns, QQ-plot and novel circular ones. United in only one bull's eye style plot, association results from multiple traits can be compared interactively, thereby to reveal both similarities and differences between signals. Additional functions include: highlight signals, a group of SNPs, chromosome visualization and candidate genes around SNPs.

Infer biological pathway activity of cells from single-cell RNA-sequencing data by calculating a pathway score for each cell (pathway genes are specified by the user). It is recommended to have the data in Transcripts-Per-Million (TPM) or Counts-Per-Million (CPM) units for best results. Scores may change when adding cells to or removing cells off the data. SiPSiC stands for Single Pathway analysis in Single Cells.

Self-organizing maps (also known as SOM, see Kohonen (2001) <doi:10.1007/978-3-642-56927-2>) are a method for dimensionality reduction and clustering of continuous data. This package introduces interactive (html) graphics for easier analysis of SOM results. It also features an interactive interface, for push-button training and visualization of SOM on numeric, categorical or mixed data, as well as tools to evaluate the quality of SOM.

This R package offers block Gibbs samplers for the Bayesian (adaptive) graphical lasso, ridge, and naive elastic net priors. These samplers facilitate the simulation of the posterior distribution of precision matrices for Gaussian distributed data and were originally proposed by: Wang (2012) <doi:10.1214/12-BA729>; Smith et al. (2022) <doi:10.48550/arXiv.2210.16290> and Smith et al. (2023) <doi:10.48550/arXiv.2306.14199>, respectively.

This package performs Correspondence Analysis on the given dataframe and plots the results in a scatterplot that emphasizes the geometric interpretation aspect of the analysis, following Borg-Groenen (2005) and Yelland (2010). It is particularly useful for highlighting the relationships between a selected row (or column) category and the column (or row) categories. See Borg-Groenen (2005, ISBN:978-0-387-28981-6); Yelland (2010) <doi:10.3888/tmj.12-4>.

Statistical tests for the comparison between two or more alpha coefficients based on either dependent or independent groups of individuals. A web interface is available at http://comparingcronbachalphas.org. A plugin for the R GUI and IDE RKWard is included. Please install RKWard from https:// rkward.kde.org to use this feature. The respective R package rkward cannot be installed directly from a repository, as it is a part of RKWard.

This package provides constrained triangulation of polygons. Ear cutting (or ear clipping) applies constrained triangulation by successively cutting triangles from a polygon defined by path/s. Holes are supported by introducing a bridge segment between polygon paths. This package wraps the header-only library earcut.hpp <https://github.com/mapbox/earcut.hpp> which includes a reference to the method used by Held, M. (2001) <doi:10.1007/s00453-001-0028-4>.

Programmatic interface to the European Centre for Medium-Range Weather Forecasts dataset web services (ECMWF; <https://www.ecmwf.int/>) and Copernicus's Data Stores. Allows for easy downloads of weather forecasts and climate reanalysis data in R. Data stores covered include the Climate Data Store (CDS; <https://cds.climate.copernicus.eu>), Atmosphere Data Store (ADS; <https://ads.atmosphere.copernicus.eu>) and Early Warning Data Store (CEMS; <https://ewds.climate.copernicus.eu>).

This package provides methods for closed testing using Simes local tests. In particular, calculates adjusted p-values for Hommel's multiple testing method, and provides lower confidence bounds for true discovery proportions. A robust but more conservative variant of the closed testing procedure that does not require the assumption of Simes inequality is also implemented. The methods have been described in detail in Goeman et al (Biometrika 106, 841-856, 2019).

Build powerful, linked-view dashboards in shiny applications. With a declarative, one-line setup, you can create bidirectional links between interactive components. When a user interacts with one element (e.g., clicking a map marker), all linked components (such as DT tables or other charts) instantly update. Supports leaflet maps, DT tables, plotly charts, and spatial data via sf objects out-of-the-box, with an extensible API for custom components.

Straightforward and detailed evaluation of machine learning models. MLeval can produce receiver operating characteristic (ROC) curves, precision-recall (PR) curves, calibration curves, and PR gain curves. MLeval accepts a data frame of class probabilities and ground truth labels, or, it can automatically interpret the Caret train function results from repeated cross validation, then select the best model and analyse the results. MLeval produces a range of evaluation metrics with confidence intervals.

Developed for the following tasks. 1- simulating realizations from the canonical, restricted, and unrestricted finite mixture models. 2- Monte Carlo approximation for density function of the finite mixture models. 3- Monte Carlo approximation for the observed Fisher information matrix, asymptotic standard error, and the corresponding confidence intervals for parameters of the mixture models sing the method proposed by Basford et al. (1997) <https://espace.library.uq.edu.au/view/UQ:57525>.

Inspired by pattern matching and enum types in Rust and many functional programming languages, this package offers an updated version of the switch function called Match that accepts atomic values, functions, expressions, and enum variants. Conditions and return expressions are separated by -> and multiple conditions can be associated with the same return expression using |'. Match also includes support for fallthrough'. The package also replicates the Result and Option enums from Rust.

Maps of Australian coastline and administrative regions. Data can be drawn or accessed directly as simple features objects. Includes simple functions for country or state maps of Australia and in-built data sets of administrative regions from the Australian Bureau of Statistics <https://www.abs.gov.au/>. Layers include electoral divisions and local government areas, simplified from the original sources but with sufficient detail to allow mapping of a local municipality.

In ancient Roman mythology, Pluto was the ruler of the underworld and presides over the afterlife. Pluto was frequently conflated with Plutus', the god of wealth, because mineral wealth was found underground. When plotting with R, you try once, twice, practice again and again, and finally you get a pretty figure you want. It's a plot tour', a tour about repetition and reward. Hope plutor helps you on the tour!

This package provides functions used for analyzing count data, mostly crime counts. Includes checking difference in two Poisson counts (e-test), checking the fit for a Poisson distribution, small sample tests for counts in bins, Weighted Displacement Difference test (Wheeler and Ratcliffe, 2018) <doi:10.1186/s40163-018-0085-5>, to evaluate crime changes over time in treated/control areas. Additionally includes functions for aggregating spatial data and spatial feature engineering.

Utilities for the Pareto, piecewise Pareto and generalized Pareto distribution that are useful for reinsurance pricing. In particular, the package provides a non-trivial algorithm that can be used to match the expected losses of a tower of reinsurance layers with a layer-independent collective risk model. The theoretical background of the matching algorithm and most other methods are described in Ulrich Riegel (2018) <doi:10.1007/s13385-018-0177-3>.

The spatial interpolation of genetic distances between samples is based on a modified kriging method that accepts a genetic distance matrix and generates a map of probability of lineage presence. This package also offers tools to generate a map of potential contact zones between groups with user-defined thresholds in the tree to account for old and recent divergence. Additionally, it has functions for IDW interpolation using genetic data and midpoints.

This package provides tools and methods to simulate populations for surveys based on auxiliary data. The tools include model-based methods, calibration and combinatorial optimization algorithms, see Templ, Kowarik and Meindl (2017) <doi:10.18637/jss.v079.i10>) and Templ (2017) <doi:10.1007/978-3-319-50272-4>. The package was developed with support of the International Household Survey Network, DFID Trust Fund TF011722 and funds from the World bank.

Slurm', Simple Linux Utility for Resource Management <https://slurm.schedmd.com/>, is a popular Linux based software used to schedule jobs in HPC (High Performance Computing) clusters. This R package provides a specialized lightweight wrapper of Slurm with a syntax similar to that found in the parallel R package. The package also includes a method for creating socket cluster objects spanning multiple nodes that can be used with the parallel package.

This implements the Brunton et al (2016; PNAS <doi:10.1073/pnas.1517384113>) sparse identification algorithm for finding ordinary differential equations for a measured system from raw data (SINDy). The package includes a set of additional tools for working with raw data, with an emphasis on cognitive science applications (Dale and Bhat, 2018 <doi:10.1016/j.cogsys.2018.06.020>). See <https://github.com/racdale/sindyr> for examples and updates.

Uses indicator species scores across binary partitions of a sample set to detect congruence in taxon-specific changes of abundance and occurrence frequency along an environmental gradient as evidence of an ecological community threshold. Relevant references include Baker and King (2010) <doi:10.1111/j.2041-210X.2009.00007.x>, King and Baker (2010) <doi:10.1899/09-144.1>, and Baker and King (2013) <doi:10.1899/12-142.1>.