Modifies dot plots to have different sizes of dots mimicking violin plots and identifies modes or peaks for them based on frequency and kernel density estimates (Rosenblatt, 1956) <doi:10.1214/aoms/1177728190> (Parzen, 1962) <doi:10.1214/aoms/1177704472>.

This package provides a wrapper for the download.file function, making it possible to download files over HTTPS across platforms. The RCurl package provides this functionality (and much more) but has external dependencies. This package has is implemented purely in R.

This package performs hypothesis tests concerning a regression function in a least-squares model, where the null is a parametric function, and the alternative is the union of large-dimensional convex polyhedral cones. See Bodhisattva Sen and Mary C Meyer (2016) <doi:10.1111/rssb.12178> for more details.

It is sometimes necessary to create documentation for all files in a directory. Doing so by hand can be very tedious. This task is made fast and reproducible using the functionality of documenter'. It aggregates all text files in a directory and its subdirectories into a single word document in a semi-automated fashion.

Microsoft Word docx files provide an XML structure that is fairly straightforward to navigate, especially when it applies to Word tables and comments. Tools are provided to determine table count/structure, comment count and also to extract/clean tables and comments from Microsoft Word docx documents. There is also nascent support for .doc and .pptx files.

Create quick and easy dot-and-whisker plots of regression results. It takes as input either (1) a coefficient table in standard form or (2) one (or a list of) fitted model objects (of any type that has methods implemented in the parameters package). It returns ggplot objects that can be further customized using tools from the ggplot2 package. The package also includes helper functions for tasks such as rescaling coefficients or relabeling predictor variables. See more methodological discussion of the visualization and data management methods used in this package in Kastellec and Leoni (2007) <doi:10.1017/S1537592707072209> and Gelman (2008) <doi:10.1002/sim.3107>.

Access diverse ggplot2'-compatible color palettes for simplified data visualization.

Build a Dockerfile straight from your R session. dockerfiler allows you to create step by step a Dockerfile, and provide convenient tools to wrap R code inside this Dockerfile.

This package provides the user with an interactive application which can be used to facilitate the planning of dose finding studies by applying the theory of optimal experimental design.

Various kinds of designs for (industrial) experiments can be created. The package uses, and sometimes enhances, design generation routines from other packages. So far, response surface designs from package rsm', Latin hypercube samples from packages lhs and DiceDesign', and D-optimal designs from package AlgDesign have been implemented.

This package creates the "table one" of bio-medical papers. Fill it with your data and the name of the variable which you'll make the group(s) out of and it will make univariate, bivariate analysis and parse it into HTML. It also allows you to visualize all your data with graphic representation.

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) <doi:10.1002/sim.6052>).

This package provides a wrapper on top of the Domino Data Python SDK library. It lets you query and access Domino Data Sources directly from your R environment. Under the hood, Domino Data R SDK leverages the API provided by the Domino Data Python SDK', which must be installed as a prerequisite. Domino is a platform that makes it easy to run your code on scalable hardware, with integrated version control and collaboration features designed for analytical workflows. See <https://docs.dominodatalab.com/en/latest/api_guide/140b48/domino-data-api> for more information.

Implement download buttons in HTML output from rmarkdown without the need for runtime:shiny'.

Local linear hazard estimator and its multiplicatively bias correction, including three bandwidth selection methods: best one-sided cross-validation, double one-sided cross-validation, and standard cross-validation.

Constructs dynamic optimal shrinkage estimators for the weights of the global minimum variance portfolio which are reconstructed at given reallocation points as derived in Bodnar, Parolya, and Thorsén (2021) (<arXiv:2106.02131>). Two dynamic shrinkage estimators are available in this package. One using overlapping samples while the other use nonoverlapping samples.

Models for detecting concreteness in natural language. This package is built in support of Yeomans (2021) <doi:10.1016/j.obhdp.2020.10.008>, which reviews linguistic models of concreteness in several domains. Here, we provide an implementation of the best-performing domain-general model (from Brysbaert et al., (2014) <doi:10.3758/s13428-013-0403-5>) as well as two pre-trained models for the feedback and plan-making domains.

Differential exon usage test for RNA-Seq data via an empirical Bayes shrinkage method for the dispersion parameter the utilizes inclusion-exclusion data to analyze the propensity to skip an exon across groups. The input data consists of two matrices where each row represents an exon and the columns represent the biological samples. The first matrix is the count of the number of reads expressing the exon for each sample. The second matrix is the count of the number of reads that either express the exon or explicitly skip the exon across the samples, a.k.a. the total count matrix. Dividing the two matrices yields proportions representing the propensity to express the exon versus skipping the exon for each sample.

CRAN packages DoE.base and Rmosek and non-'CRAN package gurobi are enhanced with functionality for the creation of optimized arrays for experimentation, where optimization is in terms of generalized minimum aberration. It is also possible to optimally extend existing arrays to larger run size. The package writes MPS (Mathematical Programming System) files for use with any mixed integer optimization software that can process such files. If at least one of the commercial products Gurobi or Mosek (free academic licenses available for both) is available, the package also creates arrays by optimization. For installing Gurobi and its R package gurobi', follow instructions at <https://www.gurobi.com/products/gurobi-optimizer/> and <https://www.gurobi.com/documentation/7.5/refman/r_api_overview.html> (or higher version). For installing Mosek and its R package Rmosek', follow instructions at <https://www.mosek.com/downloads/> and <https://docs.mosek.com/8.1/rmosek/install-interface.html>, or use the functionality in the stump CRAN R package Rmosek'.

DoubletFinder identifies doublets by generating artificial doublets from existing scRNA-seq data and defining which real cells preferentially co-localize with artificial doublets in gene expression space. Other DoubletFinder package functions are used for fitting DoubletFinder to different scRNA-seq datasets. For example, ideal DoubletFinder performance in real-world contexts requires optimal pK selection and homotypic doublet proportion estimation. pK selection is achieved using pN-pK parameter sweeps and maxima identification in mean-variance-normalized bimodality coefficient distributions. Homotypic doublet proportion estimation is achieved by finding the sum of squared cell annotation frequencies.

This is the core package that provides both the user API and developer API to deploy the parallel cluster on the cloud using the container service. The user can call clusterPreset() to define the cloud service provider and container and makeDockerCluster() to create the cluster. The developer should see "developer's cookbook" on how to define the cloud provider and container.

This package performs analysis of popular experimental designs used in the field of biological research. The designs covered are completely randomized design, randomized complete block design, factorial completely randomized design, factorial randomized complete block design, split plot design, strip plot design and latin square design. The analysis include analysis of variance, coefficient of determination, normality test of residuals, standard error of mean, standard error of difference and multiple comparison test of means. The package has functions for transformation of data and yield data conversion. Some datasets are also added in order to facilitate examples.

This package builds on Seurat's Doheatmap function code to produce a heatmap from a Seurat object with multiple annotation bars.

This is an R package that integrates the installation of doublet-detection methods. In addition, this tool is used for execution and benchmark of those eight mentioned methods.