Robust nonparametric bootstrap and permutation tests for goodness of fit, distribution equivalence, location, correlation, and regression problems, as described in Helwig (2019a) <doi:10.1002/wics.1457> and Helwig (2019b) <doi:10.1016/j.neuroimage.2019.116030>. Univariate and multivariate tests are supported. For each problem, exact tests and Monte Carlo approximations are available. Five different nonparametric bootstrap confidence intervals are implemented. Parallel computing is implemented via the parallel package.

This package provides a lightweight, fully vectorized N-body physics engine built for the R ecosystem. Simulate and visualize complex orbital mechanics, celestial trajectories, and gravitational interactions using tidy data principles. Features multiple numerical integration methods, including the energy-conserving velocity Verlet algorithm (Verlet (1967) <doi:10.1103/PhysRev.159.98>), to ensure highly stable orbital propagation. Gravitational N-body methods follow Aarseth (2003, ISBN:0-521-43272-3).

It offers a wide variety of techniques, such as graphics, recoding, or regression models, for a comprehensive analysis of patient-reported outcomes (PRO). Especially novel is the broad range of regression models based on the beta-binomial distribution useful for analyzing binomial data with over-dispersion in cross-sectional, longitudinal, or multidimensional response studies (see Najera-Zuloaga J., Lee D.-J. and Arostegui I. (2019) <doi:10.1002/bimj.201700251>).

This package provides functions to aid the identification of probable/possible duplicates in Plant Genetic Resources (PGR) collections using passport databases comprising of information records of each constituent sample. These include methods for cleaning the data, creation of a searchable Key Word in Context (KWIC) index of keywords associated with sample records and the identification of nearly identical records with similar information by fuzzy, phonetic and semantic matching of keywords.

The nature of working with structured query language ('SQL') scripts efficiently often requires the creation of temporary tables and there are few clean and simple R SQL execution approaches that allow you to complete this kind of work with the R environment. This package seeks to give SQL implementations in R a little love by deploying functions that allow you to deploy complex SQL scripts within a typical R workflow.

Sample size calculation to detect dynamic treatment regime (DTR) effects based on change in clinical attachment level (CAL) outcomes from a non-surgical chronic periodontitis treatments study. The experiment is performed under a Sequential Multiple Assignment Randomized Trial (SMART) design. The clustered tooth (sub-unit) level CAL outcomes are skewed, spatially-referenced, and non-randomly missing. The implemented algorithm is available in Xu et al. (2019+) <arXiv:1902.09386>.

Utilities for single nucleotide polymorphism (SNP) based kinship analysis testing and evaluation. The skater package contains functions for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing identity by descent (IBD) segment data. Package functions and methods are described in Turner et al. (2021) "skater: An R package for SNP-based Kinship Analysis, Testing, and Evaluation" <doi:10.1101/2021.07.21.453083>.

Similarity regression, evaluating the probability of association between sets of ontological terms and binary response vector. A no-association model is compared with one in which the log odds of a true response is linked to the semantic similarity between terms and a latent characteristic ontological profile - Phenotype Similarity Regression for Identifying the Genetic Determinants of Rare Diseases', Greene et al 2016 <doi:10.1016/j.ajhg.2016.01.008>.

Computes a point pattern in R^2 or on a graph that is representative of a collection of many data patterns. The result is an approximate barycenter (also known as Fréchet mean or prototype) based on a transport-transform metric. Possible choices include Optimal SubPattern Assignment (OSPA) and Spike Time metrics. Details can be found in Müller, Schuhmacher and Mateu (2020) <doi:10.1007/s11222-020-09932-y>.

Mixed type vectors are useful for combining semantically similar classes. Some examples of semantically related classes include time across different granularities (e.g. daily, monthly, annual) and probability distributions (e.g. Normal, Uniform, Poisson). These groups of vector types typically share common statistical operations which vary in results with the attributes of each vector. The vecvec data structure facilitates efficient storage and computation across multiple vectors within the same object.

R functions are not supposed to print text without giving the user the option to turn the printing off or on using a Boolean verbose in a construct like if(verbose) print(...)'. But this black/white approach is rather rigid, and an approach with shades of gray might be more appropriate in many circumstances. As of Version 1.4, also supports text and background colors, as well as text styles.

Toolkit to support and perform discrete event simulations with and without resource constraints in the context of health technology assessments (HTA). The package focuses on cost-effectiveness modelling and aims to be submission-ready to relevant HTA bodies in alignment with NICE TSD 15 <https://sheffield.ac.uk/nice-dsu/tsds/patient-level-simulation>. More details an examples can be found in the package website <https://jsanchezalv.github.io/WARDEN/>.

Enables researchers to sample redistricting plans from a pre-specified target distribution using Sequential Monte Carlo and Markov Chain Monte Carlo algorithms. The package allows for the implementation of various constraints in the redistricting process such as geographic compactness and population parity requirements. Tools for analysis such as computation of various summary statistics and plotting functionality are also included. The package implements the SMC algorithm of McCartan and Imai (2023) <doi:10.1214/23-AOAS1763>, the enumeration algorithm of Fifield, Imai, Kawahara, and Kenny (2020) <doi:10.1080/2330443X.2020.1791773>, the Flip MCMC algorithm of Fifield, Higgins, Imai and Tarr (2020) <doi:10.1080/10618600.2020.1739532>, the Merge-split/Recombination algorithms of Carter et al. (2019) <doi:10.48550/arXiv.1911.01503> and DeFord et al. (2021) <doi:10.1162/99608f92.eb30390f>, and the Short-burst optimization algorithm of Cannon et al. (2020) <doi:10.48550/arXiv.2011.02288>.

The R Analytic Tool To Learn Easily (Rattle) provides a collection of utilities functions for the data scientist. This package (v5.6.0) supports the companion graphical interface with the aim to provide a simple and intuitive introduction to R for data science, allowing a user to quickly load data from a CSV file transform and explore the data, and to build and evaluate models. A key aspect of the GUI is that all R commands are logged and commented through the log tab. This can be saved as a standalone R script file and as an aid for the user to learn R or to copy-and-paste directly into R itself. If you want to use the older Rattle implementing the GUI in RGtk2 (which is no longer available from CRAN) then please install the Rattle package v5.5.1. See rattle.togaware.com for instructions on installing the modern Rattle graphical user interface.

This is an alternative mechanism for importing objects from packages. The syntax allows for importing multiple objects from a package with a single command in an expressive way. The import package bridges some of the gap between using library (or require) and direct (single-object) imports. Furthermore the imported objects are not placed in the current environment. It is also possible to import objects from stand-alone .R files.

Circle Manhattan Plot is an R package that can lay out genome-wide association study P-value results in both traditional rectangular patterns, QQ-plot and novel circular ones. United in only one bull's eye style plot, association results from multiple traits can be compared interactively, thereby to reveal both similarities and differences between signals. Additional functions include: highlight signals, a group of SNPs, chromosome visualization and candidate genes around SNPs.

This package implements core utilities for single-cell RNA-seq data analysis. Contained within are utility functions for working with DE matrices and count matrices, a collection of functions for manipulating and plotting data via ggplot2, and functions to work with cell graphs and cell embeddings. Graph-based methods include embedding kNN cell graphs into a UMAP, collapsing vertices of each cluster in the graph, and propagating graph labels.

Infer biological pathway activity of cells from single-cell RNA-sequencing data by calculating a pathway score for each cell (pathway genes are specified by the user). It is recommended to have the data in Transcripts-Per-Million (TPM) or Counts-Per-Million (CPM) units for best results. Scores may change when adding cells to or removing cells off the data. SiPSiC stands for Single Pathway analysis in Single Cells.

Self-organizing maps (also known as SOM, see Kohonen (2001) <doi:10.1007/978-3-642-56927-2>) are a method for dimensionality reduction and clustering of continuous data. This package introduces interactive (html) graphics for easier analysis of SOM results. It also features an interactive interface, for push-button training and visualization of SOM on numeric, categorical or mixed data, as well as tools to evaluate the quality of SOM.

This R package offers block Gibbs samplers for the Bayesian (adaptive) graphical lasso, ridge, and naive elastic net priors. These samplers facilitate the simulation of the posterior distribution of precision matrices for Gaussian distributed data and were originally proposed by: Wang (2012) <doi:10.1214/12-BA729>; Smith et al. (2022) <doi:10.48550/arXiv.2210.16290> and Smith et al. (2023) <doi:10.48550/arXiv.2306.14199>, respectively.

Statistical tests for the comparison between two or more alpha coefficients based on either dependent or independent groups of individuals. A web interface is available at http://comparingcronbachalphas.org. A plugin for the R GUI and IDE RKWard is included. Please install RKWard from https:// rkward.kde.org to use this feature. The respective R package rkward cannot be installed directly from a repository, as it is a part of RKWard.

Estimates the per-person conditional standard error of measurement (CSEM) under the persons-by-items single-facet crossed design of Generalizability Theory, following Brennan (1998) <doi:10.1177/014662169802200401>. Implements three estimators of the relative error variance (full, large_a, uncorrelated) and the closed-form absolute error variance, with both analytical and item-resampling bootstrap sampling variances, quadratic smoothing of CSEMs on observed score, D-study extrapolation, and base-graphics plotting.

This package performs Correspondence Analysis on the given dataframe and plots the results in a scatterplot that emphasizes the geometric interpretation aspect of the analysis, following Borg-Groenen (2005) and Yelland (2010). It is particularly useful for highlighting the relationships between a selected row (or column) category and the column (or row) categories. See Borg-Groenen (2005, ISBN:978-0-387-28981-6); Yelland (2010) <doi:10.3888/tmj.12-4>.

This package provides constrained triangulation of polygons. Ear cutting (or ear clipping) applies constrained triangulation by successively cutting triangles from a polygon defined by path/s. Holes are supported by introducing a bridge segment between polygon paths. This package wraps the header-only library earcut.hpp <https://github.com/mapbox/earcut.hpp> which includes a reference to the method used by Held, M. (2001) <doi:10.1007/s00453-001-0028-4>.