This package includes functions to compute the area under the curve of selected measures: the area under the sensitivity curve (AUSEC), the area under the specificity curve (AUSPC), the area under the accuracy curve (AUACC), and the area under the receiver operating characteristic curve (AUROC). The curves can also be visualized. Support for partial areas is provided.

This package is built to perform GWAS analysis for non-Gaussian data using BG2. The BG2 method uses penalized quasi-likelihood along with nonlocal priors in a two step manner to identify SNPs in GWAS analysis. The research related to this package was supported in part by National Science Foundation awards DMS 1853549 and DMS 2054173.

Create aliases for other R names or arbitrarily complex R expressions. Accessing the alias acts as-if the aliased expression were invoked instead, and continuously reflects the current value of that expression: updates to the original expression will be reflected in the alias; and updates to the alias will automatically be reflected in the original expression.

Fit composite Gaussian process (CGP) models as described in Ba and Joseph (2012) "Composite Gaussian Process Models for Emulating Expensive Functions", Annals of Applied Statistics. The CGP model is capable of approximating complex surfaces that are not second-order stationary. Important functions in this package are CGP, print.CGP, summary.CGP, predict.CGP and plotCGP.

This package provides a set of core functions for handling medical device event data in the context of post-market surveillance, pharmacovigilance, signal detection and trending, and regulatory reporting. Primary inputs are data on events by device and data on exposures by device. Outputs include: standardized device-event and exposure datasets, defined analyses, and time series.

Takes images, imported via imager', and converts them into a data frame that can be plotted to look like the imported image. This can be used for creating data that looks like a specific image. Additionally, images with color and alpha channels can be converted to grayscale in preparation for converting to the data frame format.

An implementation of semi-supervised regression methods including self-learning and co-training by committee based on Hady, M. F. A., Schwenker, F., & Palm, G. (2009) <doi:10.1007/978-3-642-04274-4_13>. Users can define which set of regressors to use as base models from the caret package, other packages, or custom functions.

Procedures for calculation, plotting, animation, and approximation of the outputs for fuzzy numbers (see A.I. Ban, L. Coroianu, P. Grzegorzewski "Fuzzy Numbers: Approximations, Ranking and Applications" (2015)) based on the Zadeh's Extension Principle (see de Barros, L.C., Bassanezi, R.C., Lodwick, W.A. (2017) <doi:10.1007/978-3-662-53324-6_2>).

DSS is an R library performing differential analysis for count-based sequencing data. It detects differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

This package lets you record test suite HTTP requests and replay them during future runs. It works by hooking into the webmockr R package for matching HTTP requests by various rules, and then caching real HTTP responses on disk in cassettes. Subsequent HTTP requests matching any previous requests in the same cassette use a cached HTTP response.

Containing the Detrended Fluctuation Analysis (DFA), Detrended Cross-Correlation Analysis (DCCA), Detrended Cross-Correlation Coefficient (rhoDCCA), Delta Amplitude Detrended Cross-Correlation Coefficient (DeltarhoDCCA), log amplitude Detrended Fluctuation Analysis (DeltalogDFA), and the Activity Balance Index, it also includes two DFA automatic methods for identifying crossover points and a Deltalog automatic method for identifying reference channels.

This package implements several methods for testing the variance component parameter in regression models that contain kernel-based random effects, including a maximum of adjusted scores test. Several kernels are supported, including a profile hidden Markov model mutual information kernel for protein sequence. This package is described in Fong et al. (2015) <DOI:10.1093/biostatistics/kxu056>.

This package contains LUE_BIOMASS(),LUE_BIOMASS_VPD(), LUE_YIELD() and LUE_YIELD_VPD() to estimate aboveground biomass and crop yield firstly by calculating the Absorbed Photosynthetically Active Radiation (APAR) and secondly the actual values of light use efficiency with and without vapour presure deficit Shi et al.(2007) <doi:10.2134/agronj2006.0260>.

This package implements the algorithm in Chen, Wang and Samworth (2020) <arxiv:2003.03668> for online detection of sudden mean changes in a sequence of high-dimensional observations. It also implements methods by Mei (2010) <doi:10.1093/biomet/asq010>, Xie and Siegmund (2013) <doi:10.1214/13-AOS1094> and Chan (2017) <doi:10.1214/17-AOS1546>.

Constraint-based causal discovery using the PC algorithm while accounting for a partial node ordering, for example a partial temporal ordering when the data were collected in different waves of a cohort study. Andrews RM, Foraita R, Didelez V, Witte J (2021) <arXiv:2108.13395> provide a guide how to use tpc to analyse cohort data.

This package provides functions for uniform sampling of the environmental space, designed to assist species distribution modellers in gathering ecologically relevant pseudo-absence data. The method ensures balanced representation of environmental conditions and helps reduce sampling bias in model calibration. Based on the framework described by Da Re et al. (2023) <doi:10.1111/2041-210X.14209>.

This is a package for regression modeling, testing, estimation, validation, graphics, prediction, and typesetting by storing enhanced model design attributes in the fit. The rms package is a collection of functions that assist with and streamline modeling. It also contains functions for binary and ordinal logistic regression models, ordinal models for continuous Y with a variety of distribution families, and the Buckley-James multiple regression model for right-censored responses, and implements penalized maximum likelihood estimation for logistic and ordinary linear models. The package works with almost any regression model, but it was especially written to work with binary or ordinal regression models, Cox regression, accelerated failure time models, ordinary linear models, the Buckley-James model, generalized least squares for serially or spatially correlated observations, generalized linear models, and quantile regression.

R/qtl is an extension library for the R statistics system. It is used to analyze experimental crosses for identifying genes contributing to variation in quantitative traits (so-called quantitative trait loci, QTLs).

Using a hidden Markov model, R/qtl estimates genetic maps, to identify genotyping errors, and to perform single-QTL and two-QTL, two-dimensional genome scans.

Ren'Py is a visual novel engine that helps you use words, images, and sounds to tell interactive stories that run on computers and mobile devices. These can be both visual novels and life simulation games. The easy to learn script language allows anyone to efficiently write large visual novels, while its Python scripting is enough for complex simulation games.

The Parallel Mixed Model (PMM) approach is suitable for hit selection and cross-comparison of RNAi screens generated in experiments that are performed in parallel under several conditions. For example, we could think of the measurements or readouts from cells under RNAi knock-down, which are infected with several pathogens or which are grown from different cell lines.

The FAS package implements the bootstrap method for the tuning parameter selection and tuning-free inference on sparse regression coefficient vectors. Currently, the test could be applied to linear and factor-augmented sparse regressions, see Lederer & Vogt (2021, JMLR) <https://www.jmlr.org/papers/volume22/20-539/20-539.pdf> and Beyhum & Striaukas (2023) <arXiv:2307.13364>.

Implemented are the Wald-type statistic, a permuted version thereof as well as the ANOVA-type statistic for general factorial designs, even with non-normal error terms and/or heteroscedastic variances, for crossed designs with an arbitrary number of factors and nested designs with up to three factors. Friedrich et al. (2017) <doi:10.18637/jss.v079.c01>.

This package provides univariate and indexed (multivariate) nonparametric smoothed kernel estimators for the future conditional hazard rate function when time-dependent covariates are present, a bandwidth selector for the estimator's implementation and pointwise and uniform confidence bands. Methods used in the package refer to Bagkavos, Isakson, Mammen, Nielsen and Proust-Lima (2025) <doi:10.1093/biomet/asaf008>.

Identifying latent genetic interactions in genome-wide association studies using the Latent Interaction Testing (LIT) framework. LIT is a flexible kernel-based approach that leverages information across multiple traits to detect latent genetic interactions without specifying or observing the interacting variable (e.g., environment). LIT accepts standard PLINK files as inputs to analyze large genome-wide association studies.