This package provides a workflow to generate and analyze signatures based on copy number data using non-negative matrix factorization (NMF) in an approach similar to that used in mutational signatures. It can be used to extract features from Copy number segment data and use that to find a subset of copy number signatures which can be further used to correlate with other relevant data. For more on NMF see Gaujoux (2013) <doi:10.1186/1471-2105-11-367>.

Computes a structural similarity metric (after the style of MS-SSIM for images) for binary and categorical 2D and 3D images. Can be based on accuracy (simple matching), Cohen's kappa, Rand index, adjusted Rand index, Jaccard index, Dice index, normalized mutual information, or adjusted mutual information. In addition, has fast computation of Cohen's kappa, the Rand indices, and the two mutual informations. Implements the methods of Thompson and Maitra (2020) <doi:10.48550/arXiv.2004.09073>.

Bayesian and ML Emax model fitting, graphics and simulation for clinical dose response. The summary data from the dose response meta-analyses in Thomas, Sweeney, and Somayaji (2014) <doi:10.1080/19466315.2014.924876> and Thomas and Roy (2016) <doi:10.1080/19466315.2016.1256229> Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) <doi:10.1177/0962280216684528> are included in the package. The prior distributions for the Bayesian analyses default to the posterior predictive distributions derived from these references.

Flexible and robust estimation and inference of Generalised Autoregressive Conditional Heteroscedasticity (GARCH) models with covariates ('X') based on the results by Francq and Thieu (2019) <doi:10.1017/S0266466617000512>. Coefficients can straightforwardly be set to zero by omission, and quasi maximum likelihood methods ensure estimates are generally consistent and inference valid, even when the standardised innovations are non-normal and/or dependent over time. See Sucarrat (2021) <doi:10.32614/RJ-2021-057> for an overview of the package.

This package provides a forecasting method that efficiently maps vast numbers of (scalar-valued) signals into an aggregate density forecast in a time-varying and computationally fast manner. The method proceeds in two steps: First, it transforms a predictive signal into a density forecast and, second, it combines the resulting candidate density forecasts into an ultimate aggregate density forecast. For a detailed explanation of the method, please refer to Adaemmer et al. (2025) <doi:10.1080/07350015.2025.2526424>.

Estimation of multivariate differences between two groups (e.g., multivariate sex differences) with regularized regression methods and predictive approach. See Ilmarinen et al. (2023) <doi:10.1177/08902070221088155>. Deconstructing difference score correlations (e.g., gender-equality paradox), see Ilmarinen & Lönnqvist (2024) <doi:10.1037/pspp0000508>. Includes also tools that help in understanding difference score reliability, conditional intra-class correlations, tail-dependency, and heterogeneity of variance estimates. Package development was supported by the Academy of Finland research grant 338891.

This package provides a set of tools that enables using OxCal from within R. OxCal (<https://c14.arch.ox.ac.uk/oxcal.html>) is a standard archaeological tool intended to provide 14C calibration and analysis of archaeological and environmental chronological information. OxcAAR allows simple calibration with Oxcal and plotting of the results as well as the execution of sophisticated ('OxCal') code and the import of the results of bulk analysis and complex Bayesian sequential calibration.

This tool was designed to assess the sensitivity of research findings to omitted variables when estimating causal effects using propensity score (PS) weighting. This tool produces graphics and summary results that will enable a researcher to quantify the impact an omitted variable would have on their results. Burgette et al. (2021) describe the methodology behind the primary function in this package, ov_sim. The method is demonstrated in Griffin et al. (2020) <doi:10.1016/j.jsat.2020.108075>.

Automatically adding pkg:: to a function, i.e. mutate() becomes dplyr::mutate(). It is up to the user to determine which packages should be used explicitly, whether to include base R packages or use the functionality on selected text, a file, or a complete directory. User friendly logging is provided in the RStudio Markers pane. Lives in the spirit of lintr and styler'. Can also be used for checking which packages are actually used in a project.

This package implements a grammar of graphics on top of the base graphics system. A bbplot object is built incrementally with a + operator from data, aesthetic mappings and layers, then rendered with base graphics, so plotbb layers can be mixed with ordinary base plotting calls. The package provides layers for points, lines, bars, histograms, densities, boxplots, violins, ribbons, smooths, error bars and tiles, together with colour and other aesthetic scales, automatic legends, faceting, themes, coordinate flipping and significance annotations.

Loads and processes huge text corpora processed with the sally toolbox (<http://www.mlsec.org/sally/>). sally acts as a very fast preprocessor which splits the text files into tokens or n-grams. These output files can then be read with the PRISMA package which applies testing-based token selection and has some replicate-aware, highly tuned non-negative matrix factorization and principal component analysis implementation which allows the processing of very big data sets even on desktop machines.

This package implements self-organising maps combined with hierarchical cluster analysis (SOM-HCA) for clustering and visualization of high-dimensional data. The package includes functions to estimate the optimal map size based on various quality measures and to generate a model using the selected dimensions. It also performs hierarchical clustering on the map nodes or other data to group similar units. Documentation about the SOM-HCA method is provided in Pastorelli et al. (2024) <doi:10.1002/xrs.3388>.

Enables users to build ToxPi prioritization models and provides functionality within the grid framework for plotting ToxPi graphs. toxpiR allows for more customization than the ToxPi GUI (<https://toxpi.github.io/>) and integration into existing workflows for greater ease-of-use, reproducibility, and transparency. toxpiR package behaves nearly identically to the GUI; the package documentation includes notes about all differences. The vignettes download example files from <https://github.com/ToxPi/ToxPi-example-files>.

Converts between JSON text and ordinary R vectors and lists through a small, predictable set of functions, backed by vendored yyjson <https://github.com/ibireme/yyjson> and requiring no system JSON library. Parsing accepts character, raw and file input and reports failures through structured conditions; serialization writes UTF-8 bytes suitable for use directly as an HTTP request body. The type mapping is deliberately narrow and fully documented, so what goes in and what comes out are both predictable.

This package provides functions and data sets for actuarial science: modeling of loss distributions; risk theory and ruin theory; simulation of compound models, discrete mixtures and compound hierarchical models; credibility theory. It boasts support for many additional probability distributions to model insurance loss amounts and loss frequency: 19 continuous heavy tailed distributions; the Poisson-inverse Gaussian discrete distribution; zero-truncated and zero-modified extensions of the standard discrete distributions. It also supports phase-type distributions commonly used to compute ruin probabilities.

This package is for building isoscapes using mixed models and inferring the geographic origin of samples based on their isotopic ratios. This package is essentially a simplified interface to several other packages which implements a new statistical framework based on mixed models. It uses spaMM for fitting and predicting isoscapes, and assigning an organism's origin depending on its isotopic ratio. IsoriX also relies heavily on the package rasterVis for plotting the maps produced with terra using lattice'.

This package contains an implementation of a function digest() for the creation of hash digests of arbitrary R objects (using the md5, sha-1, sha-256, crc32, xxhash and murmurhash algorithms) permitting easy comparison of R language objects, as well as a function hmac() to create hash-based message authentication code.

Please note that this package is not meant to be deployed for cryptographic purposes for which more comprehensive (and widely tested) libraries such as OpenSSL should be used.

Writing interfaces to command line software is cumbersome. The cmdfun package provides a framework for building function calls to seamlessly interface with shell commands by allowing lazy evaluation of command line arguments. It also provides methods for handling user-specific paths to tool installs or secrets like API keys. Its focus is to equally serve package builders who wish to wrap command line software, and to help analysts stay inside R when they might usually leave to execute non-R software.

cogeqc aims to facilitate systematic quality checks on standard comparative genomics analyses to help researchers detect issues and select the most suitable parameters for each data set. cogeqc can be used to asses: i. genome assembly and annotation quality with BUSCOs and comparisons of statistics with publicly available genomes on the NCBI; ii. orthogroup inference using a protein domain-based approach and; iii. synteny detection using synteny network properties. There are also data visualization functions to explore QC summary statistics.

The HOPACH clustering algorithm builds a hierarchical tree of clusters by recursively partitioning a data set, while ordering and possibly collapsing clusters at each level. The algorithm uses the Mean/Median Split Silhouette (MSS) criteria to identify the level of the tree with maximally homogeneous clusters. It also runs the tree down to produce a final ordered list of the elements. The non-parametric bootstrap allows one to estimate the probability that each element belongs to each cluster (fuzzy clustering).

Package nethet is an implementation of statistical solid methodology enabling the analysis of network heterogeneity from high-dimensional data. It combines several implementations of recent statistical innovations useful for estimation and comparison of networks in a heterogeneous, high-dimensional setting. In particular, we provide code for formal two-sample testing in Gaussian graphical models (differential network and GGM-GSA; Stadler and Mukherjee, 2013, 2014) and make a novel network-based clustering algorithm available (mixed graphical lasso, Stadler and Mukherjee, 2013).

This package provides a free software for a fast and easy analysis of 1:1 molecular interaction studies. This package is suitable for a high-throughput data analysis. Both the online app and the package are completely open source. You provide a table of sensogram, tell anabel which method to use, and it takes care of all fitting details. The first two releases of anabel were created and implemented as in (<doi:10.1177/1177932218821383>, <doi:10.1093/database/baz101>).

Carries out Bland Altman analyses (also known as a Tukey mean-difference plot) as described by JM Bland and DG Altman in 1986 <doi:10.1016/S0140-6736(86)90837-8>. This package was created in 2015 as existing Bland-Altman analysis functions did not calculate confidence intervals. This package was created to rectify this, and create reproducible plots. This package is also available as a module for the jamovi statistical spreadsheet (see <https://www.jamovi.org> for more information).

Fits, validates and compares a number of Bayesian models for spatial and space time point referenced and areal unit data. Model fitting is done using several packages: rstan', INLA', spBayes', spTimer', spTDyn', CARBayes and CARBayesST'. Model comparison is performed using the DIC and WAIC, and K-fold cross-validation where the user is free to select their own subset of data rows for validation. Sahu (2022) <doi:10.1201/9780429318443> describes the methods in detail.