Project Raincat is a game developed by Carnegie Mellon students through GCS during the Fall 2008 semester. Raincat features game play inspired from classics Lemmings and The Incredible Machine. The project proved to be an excellent learning experience for the programmers. Everything is programmed in Haskell.

"Methylation-Aware Genotype Association in R" (MAGAR) computes methQTL from DNA methylation and genotyping data from matched samples. MAGAR uses a linear modeling stragety to call CpGs/SNPs that are methQTLs. MAGAR accounts for the local correlation structure of CpGs.

The Cancer Genome Atlas (TCGA) Data Portal provides a platform for researchers to search, download, and analyze data sets generated by TCGA. It contains clinical information, genomic characterization data, and high level sequence analysis of the tumor genomes. The key is to understand genomics to improve cancer care. RTCGA package offers download and integration of the variety and volume of TCGA data using patient barcode key, what enables easier data possession. This may have an benefcial infuence on impact on development of science and improvement of patients treatment. Furthermore, RTCGA package transforms TCGA data to tidy form which is convenient to use.

This package contains many functions useful for data analysis, high-level graphics, utility operations, functions for computing sample size and power, importing and annotating datasets, imputing missing values, advanced table making, variable clustering, character string manipulation, conversion of R objects to LaTeX code, and recoding variables.

Optimized XML (Ox) is a fast XML parser and object serializer for Ruby written as a native C extension. It was designed to be an alternative to Nokogiri and other Ruby XML parsers for generic XML parsing and as an alternative to Marshal for Object serialization.

Account for missing values in label-free mass spectrometry data without imputation. The package implements a probabilistic dropout model that ensures that the information from observed and missing values are properly combined. It adds empirical Bayesian priors to increase power to detect differentially abundant proteins.

This package provides methods for measuring the strength of association between a network and a phenotype. It does this by measuring clustering of the phenotype across the network (Knet). Vertices can also be individually ranked by their strength of association with high-weight vertices (Knode).

This package addresses the mean-variance relationship in spatially resolved transcriptomics data. Precision weights are generated for individual observations using Empirical Bayes techniques. These weights are used to rescale the data and covariates, which are then used as input in spatially variable gene detection tools.

Sensitivity (or recall or true positive rate), false positive rate, specificity, precision (or positive predictive value), negative predictive value, misclassification rate, accuracy, F-score---these are popular metrics for assessing performance of binary classifiers for certain thresholds. These metrics are calculated at certain threshold values. Receiver operating characteristic (ROC) curve is a common tool for assessing overall diagnostic ability of the binary classifier. Unlike depending on a certain threshold, area under ROC curve (also known as AUC), is a summary statistic about how well a binary classifier performs overall for the classification task. The ROCit package provides flexibility to easily evaluate threshold-bound metrics.

The ASAFE package contains a collection of functions that can be used to carry out an EM (Expectation–maximization) algorithm to estimate ancestry-specific allele frequencies for a bi-allelic genetic marker, e.g. an SNP (single nucleotide polymorphism) from genotypes and ancestry pairs.

The SciViews svGUI package eases the management of Graphical User Interfaces (GUI) in R. It is independent from any particular GUI widgets. It centralizes info about GUI elements currently used, and it dispatches GUI calls to the particular toolkits in use in function of the context.

RipperX is a GTK program to rip CD audio tracks and encode them to the Ogg, MP3, or FLAC formats. Its goal is to be easy to use, requiring only a few mouse clicks to convert an entire album. It supports CDDB lookups for album and track information.

This package provides an interface to simulate metabolic reconstruction from the BiGG database and other metabolic reconstruction databases. The package facilitates flux balance analysis (FBA) and the sampling of feasible flux distributions. Metabolic networks and estimated fluxes can be visualized with hypergraphs.

Pando leverages multi-modal single-cell measurements to infer gene regulatory networks using a flexible linear model-based framework. By modeling the relationship between TF-binding site pairs with the expression of target genes, Pando simultaneously infers gene modules and sets of regulatory regions for each transcription factor.

SeqGL is a group lasso based algorithm to extract transcription factor sequence signals from ChIP, DNase and ATAC-seq profiles. This package presents a method which uses group lasso to discriminate between bound and non bound genomic regions to accurately identify transcription factors bound at the specific regions.

This Package utilizes a Semi-parametric Differential Abundance/expression analysis (SDA) method for metabolomics and proteomics data from mass spectrometry as well as single-cell RNA sequencing data. SDA is able to robustly handle non-normally distributed data and provides a clear quantification of the effect size.

This package lets you create extra Analysis Results Data (ARD) summary objects. The package supplements the simple ARD functions from the cards package, exporting functions to put statistical results in the ARD format. These objects are used and re-used to construct summary tables, visualizations, and written reports.

This package provides a header only, C++11 interface to R's C interface. Compared to other approaches cpp11 strives to be safe against long jumps from the C API as well as C++ exceptions, conform to normal R function semantics and supports interaction with ALTREP vectors.

Users may want to align plots with associated information that requires axes to be exactly matched in subplots, e.g. hierarchical clustering with a heatmap. This package provides utilities to align associated subplots to a main plot at different sides (left, right, top and bottom) with axes exactly matched.

This package lets you construct Clinical Data Interchange Standards Consortium (CDISC) compliant Analysis Results Data objects. These objects are used and re-used to construct summary tables, visualizations, and written reports. The package also exports utilities for working with these objects and creating new Analysis Results Data objects.

Rsyslog offers high-performance, great security features and a modular design. While it started as a regular syslogd, rsyslog has evolved into a kind of swiss army knife of logging, being able to accept inputs from a wide variety of sources, transform them, and output the results to diverse destinations.

PhosR is a package for the comprenhensive analysis of phosphoproteomic data. There are two major components to PhosR: processing and downstream analysis. PhosR consists of various processing tools for phosphoproteomics data including filtering, imputation, normalisation, and functional analysis for inferring active kinases and signalling pathways.

The qsvaR package contains functions for removing the effect of degration in rna-seq data from postmortem brain tissue. The package is equipped to help users generate principal components associated with degradation. The components can be used in differential expression analysis to remove the effects of degradation.

The rocRAND project provides functions that generate pseudorandom and quasirandom numbers. The rocRAND library is implemented in the HIP programming language and optimized for AMD's latest discrete GPUs. It is designed to run on top of AMD's ROCm runtime, but it also works on CUDA-enabled GPUs.