This package provides a new methodology for linear regression with both curve response and curve regressors, which is described in Cho, Goude, Brossat and Yao (2013) <doi:10.1080/01621459.2012.722900> and (2015) <doi:10.1007/978-3-319-18732-7_3>. The key idea behind this methodology is dimension reduction based on a singular value decomposition in a Hilbert space, which reduces the curve regression problem to several scalar linear regression problems.

This package implements various decision support tools related to the Econometrics & Technometrics. Subroutines include correlation reliability test, Mahalanobis distance measure for outlier detection, combinatorial search (all possible subset regression), non-parametric efficiency analysis measures: DDF (directional distance function), DEA (data envelopment analysis), HDF (hyperbolic distance function), SBM (slack-based measure), and SF (shortage function), benchmarking, Malmquist productivity analysis, risk analysis, technology adoption model, new product target setting, network DEA, dynamic DEA, intertemporal budgeting, etc.

Computes the InterModel Vigorish ('IMV'), a metric for comparing the predictive accuracy of two models for binary outcomes. The IMV is derived from the expected value of a bettor using one model's predicted probabilities against those of a competing model, and is estimated via k-fold cross-validation. Methods are provided for generalized linear models, mixed-effects models ('lme4'), and item response theory models ('mirt'). See <doi:10.1371/journal.pone.0316491>.

Build, compose, stack, sum, and realize feed-forward neural networks as algebraic objects. Implements the calculus and constructive approximations described by Rafi, Padgett, and Nakarmi (2024) <doi:10.48550/arXiv.2402.01058>, Grohs, Hornung, Jentzen, et al. (2023) <doi:10.1007/s10444-022-09970-2>, and Jentzen, Kuckuck, and von Wurstemberger (2023) <doi:10.48550/arXiv.2310.20360>. Includes neural network polynomials, transcendental-function approximations, multidimensional maximum convolution, and vectorized batch realization.

Efficiently estimate shape parameters of periodic time series imagery with which a statistical seasonal trend analysis (STA) is subsequently performed. STA output can be exported in conventional raster formats. Methods to visualize STA output are also implemented as well as the calculation of additional basic statistics. STA is based on (R. Eastman, F. Sangermano, B. Ghimire, H. Zhu, H. Chen, N. Neeti, Y. Cai, E. Machado and S. Crema, 2009) <doi:10.1080/01431160902755338>.

This package provides a new measure of similarity between a pair of mass spectrometry (MS) experiments, called truncated rank correlation (TRC). To provide a robust metric of similarity in noisy high-dimensional data, TRC uses truncated top ranks (or top m-ranks) for calculating correlation. Truncated rank correlation as a robust measure of test-retest reliability in mass spectrometry data. For more details see Lim et al. (2019) <doi:10.1515/sagmb-2018-0056>.

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Variance function estimation for models proposed by W. Sadler in his variance function program ('VFP', www.aacb.asn.au/AACB/Resources/Variance-Function-Program). Here, the idea is to fit multiple variance functions to a data set and consequently assess which function reflects the relationship Var ~ Mean best. For in-vitro diagnostic ('IVD') assays modeling this relationship is of great importance when individual test-results are used for defining follow-up treatment of patients.

This package provides methods to calculate the expected value of information from a decision-analytic model. This includes the expected value of perfect information (EVPI), partial perfect information (EVPPI) and sample information (EVSI), and the expected net benefit of sampling (ENBS). A range of alternative computational methods are provided under the same user interface. See Heath et al. (2024) <doi:10.1201/9781003156109>, Jackson et al. (2022) <doi:10.1146/annurev-statistics-040120-010730>.

Alternating least squares is often used to resolve components contributing to data with a bilinear structure; the basic technique may be extended to alternating constrained least squares. This package provides an implementation of multivariate curve resolution alternating least squares (MCR-ALS).

Commonly applied constraints include unimodality, non-negativity, and normalization of components. Several data matrices may be decomposed simultaneously by assuming that one of the two matrices in the bilinear decomposition is shared between datasets.

This package provides tools for evaluating timely epidemic detection models within school absenteeism-based surveillance systems. Introduces the concept of alert time quality as an evaluation metric. Includes functions to simulate populations, epidemics, and alert metrics associated with epidemic spread using population census data. The methods are based on research published in Vanderkruk et al. (2023) <doi:10.1186/s12889-023-15747-z> and Ward et al. (2019) <doi:10.1186/s12889-019-7521-7>.

Using the Theory of Belief Functions for evidence calculus. Basic probability assignments, or mass functions, can be defined on the subsets of a set of possible values and combined. A mass function can be extended to a larger frame. Marginalization, i.e. reduction to a smaller frame can also be done. These features can be combined to analyze small belief networks and take into account situations where information cannot be satisfactorily described by probability distributions.

Eco-phylogenetic and community phylogenetic analyses. Keeps community ecological and phylogenetic data matched up and comparable using comparative.comm objects. Wrappers for common community phylogenetic indices ('pez.shape', pez.evenness', pez.dispersion', and pez.dissimilarity metrics). Implementation of Cavender-Bares (2004) correlation of phylogenetic and ecological matrices ('fingerprint.regression'). Phylogenetic Generalised Linear Mixed Models (PGLMMs; pglmm') following Ives & Helmus (2011) and Rafferty & Ives (2013). Simulation of null assemblages, traits, and phylogenies ('scape', sim.meta.comm').

This package provides interactive three-dimensional visualization of p-value surfaces for single-sample t-tests. Enables simultaneous exploration of effect size, sample size, and significance level, making the continuous nature of p-values and the moderating effect of sample size visually apparent. Includes both interactive ('rgl', plotly') and static (persp()) rendering options. The p-value surface is based on the approach of Infanger and Schmidt-Trucksäss (2019) <doi:10.1002/sim.8293>.

Generates Skew Factor Models data and applies Sparse Online Principal Component (SOPC), Incremental Principal Component (IPC), Projected Principal Component (PPC), Perturbation Principal Component (PPC), Stochastic Approximation Principal Component (SAPC), Sparse Principal Component (SPC) and other PC methods to estimate model parameters. It includes capabilities for calculating mean squared error, relative error, and sparsity of the loading matrix.The philosophy of the package is described in Guo G. (2023) <doi:10.1007/s00180-022-01270-z>.

Implement the transformed additive Gaussian (TAG) process and the transformed approximately additive Gaussian (TAAG) process proposed in Lin and Joseph (2020) <DOI:10.1080/00401706.2019.1665592>. These functions can be used to model deterministic computer experiments, obtain predictions at new inputs, and quantify the uncertainty of the predictions. This research is supported by a U.S. National Science Foundation grant DMS-1712642 and a U.S. Army Research Office grant W911NF-17-1-0007.

Computes exact observation weights for the Kalman filter and smoother, following Koopman and Harvey (2003) <www.sciencedirect.com/science/article/pii/S0165188902000611>. The package provides tools for analyzing linear Gaussian state-space models, allowing users to quantify the contribution of individual observations to filtered and smoothed state estimates. These weights can be used for interpretation, decomposition, and diagnostic analysis in time series models, including applications such as dynamic factor models. See the README for examples.

This algorithm conducts variable selection in the classification setting. It repeatedly subsamples variables and runs linear discriminant analysis (LDA) on the subsampled variables. Variables are scored based on the AUC and the t-statistics. Variables then enter a competition and the semi-finalist variables will be evaluated in a final round of LDA classification. The algorithm then outputs a list of variable selected. Qiao, Sun and Fan (2017) <http://people.math.binghamton.edu/qiao/swa.html>.

This package provides tools to calculate trait probability density functions (TPD) at any scale (e.g. populations, species, communities). TPD functions are used to compute several indices of functional diversity, as well as its partition across scales. These indices constitute a unified framework that incorporates the underlying probabilistic nature of trait distributions into uni- or multidimensional functional trait-based studies. See Carmona et al. (2016) <doi:10.1016/j.tree.2016.02.003> for further information.

This package uses a Bayesian hierarchical model to detect enriched regions from ChIP-chip experiments. The common goal in analyzing this ChIP-chip data is to detect DNA-protein interactions from ChIP-chip experiments. The BAC package has mainly been tested with Affymetrix tiling array data. However, we expect it to work with other platforms (e.g. Agilent, Nimblegen, cDNA, etc.). Note that BAC does not deal with normalization, so you will have to normalize your data beforehand.

Roary is a high speed stand alone pan genome pipeline, which takes annotated assemblies in GFF3 format (produced by the Prokka program) and calculates the pan genome. Using a standard desktop PC, it can analyse datasets with thousands of samples, without compromising the quality of the results. 128 samples can be analysed in under 1 hour using 1 GB of RAM and a single processor. Roary is not intended for metagenomics or for comparing extremely diverse sets of genomes.

This package is designed as an integrated package for genetic data analysis of both population and family data. Currently, it contains functions for sample size calculations of both population-based and family-based designs, probability of familial disease aggregation, kinship calculation, statistics in linkage analysis, and association analysis involving genetic markers including haplotype analysis with or without environmental covariates. Over years, the package has been developed in-between many projects hence also in line with the name (gap).

The irregularly-spaced data are interpolated onto regular latitude-longitude grids by weighting each station according to its distance and angle from the center of a search radius. In addition to this, we also provide a simple way (Jones and Hulme, 1996) to grid the irregularly-spaced data points onto regular latitude-longitude grids by averaging all stations in grid-boxes. This study was supported by the National Natural Science Foundation of China (NSFC, Grant No. 42205177).

This package provides a system for importing electrophysiological signal, based on the Waveform Database (WFDB) software package, written by Moody et al 2022 <doi:10.13026/gjvw-1m31>. A R-based system to utilize WFDB functions for reading and writing signal data, as well as functions for visualization and analysis are provided. A stable and broadly compatible class for working with signal data, supporting the reading in of cardiac electrophysiological files such as intracardiac electrograms, is introduced.