This package provides a collection of functions to perform various meta-analytical models through a unified mixed-effects framework, including standard univariate fixed and random-effects meta-analysis and meta-regression, and non-standard extensions such as multivariate, multilevel, longitudinal, and dose-response models.

Calculate Krippendorff's alpha for multi-valued data using the methods introduced by Krippendorff and Craggs (2016) <doi:10.1080/19312458.2016.1228863>. Nominal, ordinal, interval, and ratio data types are supported, with options to create bootstrapped estimates of alpha and/or parallelize calculations.

This package provides an interface to OpenML.org to list and download machine learning data, tasks and experiments. The OpenML objects can be automatically converted to mlr3 objects. For a more sophisticated interface with more upload options, see the OpenML package.

This package provides an R interface to the OMOPHub API for accessing OHDSI ATHENA standardized medical vocabularies. Supports concept search, semantic search using neural embeddings, concept similarity, vocabulary exploration, hierarchy navigation, relationship queries, concept mappings, and FHIR-to-OMOP concept resolution with automatic pagination.

Retrieve data from the Our World in Data (OWID) Chart API <https://docs.owid.io/projects/etl/api/>. OWID provides public access to more than 5,000 charts focusing on global problems such as poverty, disease, hunger, climate change, war, existential risks, and inequality.

This package provides tools for modelling populations and demography using matrix projection models, with deterministic and stochastic model implementations. Includes population projection, indices of short- and long-term population size and growth, perturbation analysis, convergence to stability or stationarity, and diagnostic and manipulation tools.

Generate simulated datasets from an initial underlying distribution and apply transformations to obtain realistic data. Implements the NORTA (Normal-to-anything) approach from Cario and Nelson (1997) and other data generating mechanisms. Simple network visualization tools are provided to facilitate communicating the simulation setup.

This package provides a system enables cross study Analysis by extracting and filtering study data for control animals from CDISC SEND Study Repository. These data types are supported: Body Weights, Laboratory test results and Microscopic findings. These database types are supported: SQLite and Oracle'.

Easily create alerts, notifications, modals, info tips and loading screens in Shiny'. Includes several options to customize alerts and notifications by including text, icons, images and buttons. When wrapped around a Shiny output, loading screen is automatically displayed while the output is being recalculated.

It fits scale mixture of skew-normal linear mixed models using either an expectationâ maximization (EM) type algorithm or its accelerated version (Damped Anderson Acceleration with Epsilon Monotonicity, DAAREM), including some possibilities for modeling the within-subject dependence <doi:10.18637/jss.v115.i07>.

This package provides a template for new research projects structured as an R package-based research compendium. Everything - data, R scripts, custom functions and manuscript or reports - is contained within the same package to facilitate collaboration and promote reproducible research, following the FAIR principles.

Swift and seamless Single Sign-On (SSO) integration. Designed for effortless compatibility with popular Single Sign-On providers like Google and Microsoft, it streamlines authentication, enhancing both user experience and application security. Elevate your shiny applications for a simplified, unified, and secure authentication process.

This package implements an algorithm for variable selection in high-dimensional linear regression using the "tilted correlation", a new way of measuring the contribution of each variable to the response which takes into account high correlations among the variables in a data-driven way.

Azimuth utilizes an annotated reference dataset. It automates the processing, analysis, and interpretation. This applies specifically to new single-cell RNA-seq or ATAC-seq experiments. Azimuth leverages a reference-based mapping pipeline that inputs accounts matrix and performs normalization, visualization, cell annotation, and differential expression.

Similarity Network Fusion takes multiple views of a network and fuses them together to construct an overall status matrix. The input to our algorithm can be feature vectors, pairwise distances, or pairwise similarities. The learned status matrix can then be used for retrieval, clustering, and classification.

The package offers four network inference statistical models using Dynamic Bayesian Networks and Gibbs Variable Selection: a linear interaction model, two linear interaction models with added experimental noise (Gaussian and Student distributed) for the case where replicates are available and a non-linear interaction model.

Topological pathway analysis tool able to integrate multi-omics data. It finds survival-associated modules or significant modules for two-class analysis. This tool have two main methods: pathway tests and module tests. The latter method allows the user to dig inside the pathways itself.

The package is unified implementation of MeSH.db, MeSH.AOR.db, and MeSH.PCR.db and also is interface to construct Gene-MeSH package (MeSH.XXX.eg.db). loadMeSHDbiPkg import sqlite file and generate MeSH.XXX.eg.db.

Scafari is a Shiny application designed for the analysis of single-cell DNA sequencing (scDNA-seq) data provided in .h5 file format. The analysis process is structured into the four key steps "Sequencing", "Panel", "Variants", and "Explore Variants". It supports various analyses and visualizations.

Create data that displays generative art when mapped into a ggplot2 plot. Functionality includes specialized data frame creation for geometric shapes, tools that define artistic color palettes, tools for geometrically transforming data, and other miscellaneous tools that are helpful when using ggplot2 for generative art.

This package provides a novel data-augmentation Markov chain Monte Carlo sampling algorithm to fit a progressive compartmental model of disease in a Bayesian framework Morsomme, R.N., Holloway, S.T., Ryser, M.D. and Xu J. (2024) <doi:10.48550/arXiv.2408.14625>.

Calculation of physical (e.g. aerodynamic conductance, surface temperature), and physiological (e.g. canopy conductance, water-use efficiency) ecosystem properties from eddy covariance data and accompanying meteorological measurements. Calculations assume the land surface to behave like a big-leaf and return bulk ecosystem/canopy variables.

An implementation of Fan plots for cytometry data in ggplot2'. For reference see Britton, E.; Fisher, P. & J. Whitley (1998) The Inflation Report Projections: Understanding the Fan Chart <https://www.bankofengland.co.uk/quarterly-bulletin/1998/q1/the-inflation-report-projections-understanding-the-fan-chart>).

We aim to deal with the average treatment effect (ATE), where the data are subject to high-dimensionality and measurement error. This package primarily contains two functions, which are used to generate artificial data and estimate ATE with high-dimensional and error-prone data accommodated.