This package provides functions provide comprehensive treatments for estimating, inferring, testing and model selecting in linear regression models with structural breaks. The tests, estimation methods, inference and information criteria implemented are discussed in Bai and Perron (1998) "Estimating and Testing Linear Models with Multiple Structural Changes" <doi:10.2307/2998540>.

Multivariate Normal (i.e. Gaussian) Mixture Models (S3) Classes. Fitting models to data using MLE (maximum likelihood estimation) for multivariate normal mixtures via smart parametrization using the LDL (Cholesky) decomposition, see McLachlan and Peel (2000, ISBN:9780471006268), Celeux and Govaert (1995) <doi:10.1016/0031-3203(94)00125-6>.

This package provides a doubly robust precision medicine approach to fit, cross-validate and visualize prediction models for the conditional average treatment effect (CATE). It implements doubly robust estimation and semiparametric modeling approach of treatment-covariate interactions as proposed by Yadlowsky et al. (2020) <doi:10.1080/01621459.2020.1772080>.

Easily visualize and animate tabledap and griddap objects obtained via the rerddap package in a simple one-line command, using either base graphics or ggplot2 graphics. plotdap handles extracting and reshaping the data, map projections and continental outlines. Optionally the data can be animated through time using the gganmiate package.

Computes the entire solution paths for Support Vector Regression(SVR) with respect to the regularization parameter, lambda and epsilon in epsilon-intensive loss function, efficiently. We call each path algorithm svrpath and epspath. See Wang, G. et al (2008) <doi:10.1109/TNN.2008.2002077> for details regarding the method.

The PSMatch package helps proteomics practitioners to load, handle and manage peptide spectrum matches. It provides functions to model peptide-protein relations as adjacency matrices and connected components, visualise these as graphs and make informed decision about shared peptide filtering. The package also provides functions to calculate and visualise MS2 fragment ions.

This package provides a function to format R source code. Spaces and indent will be added to the code automatically, and comments will be preserved under certain conditions, so that R code will be more human-readable and tidy. There is also a Shiny app as a user interface in this package.

This package offers features plots for mlr3 objects such as tasks, learners, predictions, benchmark results, tuning instances and filters via the autoplot() generic of ggplot2. The mlr3viz package draws plots with the viridis color palette and applies the minimal theme. Visualizations include barplots, boxplots, histograms, ROC curves, and precision-recall curves.

This package provides tools to identify global ("unknown" or "free") objects in R expressions by code inspection using various strategies, e.g. conservative or liberal. The objective of this package is to make it as simple as possible to identify global objects for the purpose of exporting them in distributed compute environments.

Puma is a simple, fast, threaded, and highly concurrent HTTP 1.1 server for Ruby/Rack applications. Puma is intended for use in both development and production environments. In order to get the best throughput, it is highly recommended that you use a Ruby implementation with real threads like Rubinius or JRuby.

Pathway Expression Profiles (PEPs) are based on the expression of pathways (defined as sets of genes) as opposed to individual genes. This package converts gene expression profiles to PEPs and performs enrichment analysis of both pathways and experimental conditions, such as "drug set enrichment analysis" and "gene2drug" drug discovery analysis respectively.

Exploratory data analysis methods to summarize, visualize and describe datasets. The main principal component methods are available, those with the largest potential in terms of applications: principal component analysis (PCA) when variables are quantitative, correspondence analysis (CA) when variables are categorical, Multiple Factor Analysis (MFA) when variables are structured in groups.

This package implements a class and methods to work with sets, doing intersection, union, complementary sets, power sets, cartesian product and other set operations in a "tidy" way. These set operations are available for both classical sets and fuzzy sets. Import sets from several formats or from other several data structures.

This package provides tools for fitting bivariate hurdle negative binomial models with horseshoe priors, Bayesian Model Averaging (BMA) via stacking, and comprehensive causal inference methods including G-computation, transfer entropy, Threshold Vector Autoregressive (TVAR) and Smooth Transition Autoregressive (STAR) models, Dynamic Bayesian Networks (DBN), Hidden Markov Models (HMM), and sensitivity analysis.

This package provides functions are pre-configured to utilize Bootstrap 5 classes and HTML structures to create Bootstrap-styled HTML quickly and easily. Includes functions for creating common Bootstrap elements such as containers, rows, cols, navbars, etc. Intended to be used with the html5 package. Learn more at <https://getbootstrap.com/>.

This package provides access to the Calcite Design System javascript components via integration with the htmltools and shiny packages. Pre-built and interactive components can be used to generate either static html or interactive web applications. Learn more about the Calcite Design System at <https://developers.arcgis.com/calcite-design-system/>.

Colorful Data Frames in the terminal. The new class does change the behaviour of any of the objects, but adds a style definition and a print method. Using ANSI escape codes, it colors the terminal output of data frames. Some column types (such as p-values and identifiers) are automatically recognized.

An implementation of the clugen algorithm for generating multidimensional clusters with arbitrary distributions. Each cluster is supported by a line segment, the position, orientation and length of which guide where the respective points are placed. This package is described in Fachada & de Andrade (2023) <doi:10.1016/j.knosys.2023.110836>.

Fast and very memory-efficient calculation of isotope patterns, subsequent convolution to theoretical envelopes (profiles) plus valley detection and centroidization or intensoid calculation. Batch processing, resolution interpolation, wrapper, adduct calculations and molecular formula parsing. Loos, M., Gerber, C., Corona, F., Hollender, J., Singer, H. (2015) <doi:10.1021/acs.analchem.5b00941>.

High-order functions for data manipulation : sort or group data, given one or more auxiliary functions. Functions are inspired by other pure functional programming languages ('Haskell mainly). The package also provides built-in function operators for creating compact anonymous functions, as well as the possibility to use the purrr package syntax.

Function factories are functions that make functions. They can be confusing to construct. Straightforward techniques can produce functions that are fragile or hard to understand. While more robust techniques exist to construct function factories, those techniques can be confusing. This package is designed to make it easier to construct function factories.

Extends the capabilities for flexible partitioning and model-based clustering available in the packages flexclust and flexmix to handle ordinal and mixed-with-ordinal data types via new distance, centroid and driver functions that make various assumptions regarding ordinality. Using them within the flex-scheme allows for easy comparisons across methods.

Statistical tool set for population genetics. The package provides following functions: 1) empirical Bayes estimator of Fst and other measures of genetic differentiation, 2) regression analysis of environmental effects on genetic differentiation using bootstrap method, 3) interfaces to read and manipulate GENEPOP format data files and allele/haplotype frequency format files.

Calculates Agresti's generalized odds ratios. For a randomly selected pair of observations from two groups, calculates the odds that the second group will have a higher scoring outcome than that of the first group. Package provides hypothesis testing for if this odds ratio is significantly different to 1 (equal chance).