This package provides a Bayesian credible interval is interpreted with respect to posterior probability, and this interpretation is far more intuitive than that of a frequentist confidence interval. However, standard highest-density intervals can be wide due to between-subjects variability and tends to hide within-subject effects, rendering its relationship with the Bayes factor less clear in within-subject (repeated-measures) designs. This urgent issue can be addressed by using within-subject intervals in within-subject designs, which integrate four methods including the Wei-Nathoo-Masson (2023) <doi:10.3758/s13423-023-02295-1>, the Loftus-Masson (1994) <doi:10.3758/BF03210951>, the Nathoo-Kilshaw-Masson (2018) <doi:10.1016/j.jmp.2018.07.005>, and the Heck (2019) <doi:10.31234/osf.io/whp8t> interval estimates.

This package provides a data-driven test for the assumptions of quantile normalization using raw data such as objects that inherit eSets (e.g. ExpressionSet, MethylSet). Group level information about each sample (such as Tumor / Normal status) must also be provided because the test assesses if there are global differences in the distributions between the user-defined groups.

Sending functions to remote processes can be wasteful of resources because they carry their environments with them. With this package, it is easy to create functions that are isolated from their environment. These isolated functions, also called crates, print to the console with their total size and can be easily tested locally before being sent to a remote.

This package translates microarray expression data into metadata of reduced dimension. It provides various sample-centered and group-centered visualizations, sample similarity analyses and functional enrichment analyses. The underlying SOM algorithm combines feature clustering, multidimensional scaling and dimension reduction, along with strong visualization capabilities. It enables extraction and description of functional expression modules inherent in the data.

This package provides a single sample pathway perturbation testing method for RNA-seq data. The method propagates changes in gene expression down gene-set topologies to compute single-sample directional pathway perturbation scores that reflect potential direction of change. Perturbation scores can be used to test significance of pathway perturbation at both individual-sample and treatment levels.

Make summary tables for descriptive statistics and select explanatory variables automatically in various regression models. Support linear models, generalized linear models and cox-proportional hazard models. Generate publication-ready tables summarizing result of regression analysis and plots. The tables and plots can be exported in "HTML", "pdf('LaTex')", "docx('MS Word')" and "pptx('MS Powerpoint')" documents.

Offers several functions for Configural Frequencies Analysis (CFA), which is a useful statistical tool for the analysis of multiway contingency tables. CFA was introduced by G. A. Lienert as Konfigurations Frequenz Analyse - KFA'. Lienert, G. A. (1971). Die Konfigurationsfrequenzanalyse: I. Ein neuer Weg zu Typen und Syndromen. Zeitschrift für Klinische Psychologie und Psychotherapie, 19(2), 99â 115.

Dependent censoring regression models for survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2019) <doi:10.1002/bimj.201800391>.

This package provides various statistical methods for evaluating Individualized Treatment Rules under randomized data. The provided metrics include Population Average Value (PAV), Population Average Prescription Effect (PAPE), Area Under Prescription Effect Curve (AUPEC). It also provides the tools to analyze Individualized Treatment Rules under budget constraints. Detailed reference in Imai and Li (2019) <arXiv:1905.05389>.

This package provides a system to facilitate designing comparative (and non-comparative) experiments using the grammar of experimental designs <https://emitanaka.org/edibble-book/>. An experimental design is treated as an intermediate, mutable object that is built progressively by fundamental experimental components like units, treatments, and their relation. The system aids in experimental planning, management and workflow.

Extends the fitdist() (from fitdistrplus') adding the Anderson-Darling ad.test() (from ADGofTest') and Kolmogorov Smirnov Test ks.test() inside, trying the distributions from stats package by default and offering a second function which uses mixed distributions to fit, this distributions are split with unsupervised learning, with Mclust() function (from mclust').

This package provides a collection of utility functions for working with Year Month Day objects. Includes functions for fast parsing of numeric and character input based on algorithms described in Hinnant, H. (2021) <https://howardhinnant.github.io/date_algorithms.html> as well as a branchless calculation of leap years by Jerichaux (2025) <https://stackoverflow.com/a/79564914>.

Access business registration data from the Dutch Chamber of Commerce (Kamer van Koophandel, KvK) through their official API <https://developers.kvk.nl/>. Search for companies by name, location, or registration number. Retrieve detailed business profiles, establishment information, and company name histories. Built on httr2 for robust API interaction with automatic pagination, error handling, and usage tracking.

Read Swiss time series data from the KOF Data API, <https://datenservice.kof.ethz.ch>. The API provides macro economic time series data mostly about Switzerland. The package itself is a set of wrappers around the KOF Datenservice API. The kofdata package is able to consume public information as well as data that requires an API token.

Statistical framework for comparing sets of trees using hypothesis testing methods. Designed for transmission trees, phylogenetic trees, and directed acyclic graphs (DAGs), the package implements chi-squared tests to compare edge frequencies between sets and PERMANOVA to analyse topological dissimilarities with customisable distance metrics, following Anderson (2001) <doi:10.1111/j.1442-9993.2001.01070.pp.x>.

The mFilter package implements several time series filters useful for smoothing and extracting trend and cyclical components of a time series. The routines are commonly used in economics and finance, however they should also be interest to other areas. Currently, Christiano-Fitzgerald, Baxter-King, Hodrick-Prescott, Butterworth, and trigonometric regression filters are included in the package.

Software to aid in modeling and analyzing mass-spectrometry-based proteome melting data. Quantitative data is imported and normalized and thermal behavior is modeled at the protein level. Methods exist for normalization, modeling, visualization, and export of results. For a general introduction to MS-based thermal profiling, see Savitski et al. (2014) <doi:10.1126/science.1255784>.

This package performs network meta-analysis using integrated nested Laplace approximations ('INLA') which is described in Guenhan, Held, and Friede (2018) <doi:10.1002/jrsm.1285>. Includes methods to assess the heterogeneity and inconsistency in the network. Contains more than ten different network meta-analysis dataset. INLA package can be obtained from <https://www.r-inla.org>.

Uniform random samples from simple manifolds, sometimes with noise, are commonly used to test topological data analytic (TDA) tools. This package includes samplers powered by two techniques: analytic volume-preserving parameterizations, as employed by Arvo (1995) <doi:10.1145/218380.218500>, and rejection sampling, as employed by Diaconis, Holmes, and Shahshahani (2013) <doi:10.1214/12-IMSCOLL1006>.

An interface to the mclust package to easily carry out latent profile analysis ("LPA"). Provides functionality to estimate commonly-specified models. Follows a tidy approach, in that output is in the form of a data frame that can subsequently be computed on. Also has functions to interface to the commercial MPlus software via the MplusAutomation package.

Plots ternary diagrams (simplex plots / Gibbs triangles) and Holdridge life zone plots <doi:10.1126/science.105.2727.367> using the standard graphics functions. Allows custom annotation, interpolating, contouring and scaling of plotting region. Includes a Shiny user interface for point-and-click ternary plotting. An alternative to ggtern', which uses the ggplot2 family of plotting functions.

This package helps with quality checks, visualizations and analysis of mass spectrometry data, coming from proteomics experiments. The package is developed, tested and used at the Functional Genomics Center Zurich, where it is used mainly for prototyping, teaching, and having fun with proteomics data. But it can also be used to do data analysis for small scale data sets.

This package provides various themes, palettes, and other functions that are used to customise ggplots to look like they were made in GraphPad Prism. The Prism-look is achieved with theme_prism() and scale_fill|colour_prism(), axes can be changed with custom guides like guide_prism_minor(), and significance indicators added with add_pvalue().

R is a language and environment for statistical computing and graphics. It provides a variety of statistical techniques, such as linear and nonlinear modeling, classical statistical tests, time-series analysis, classification and clustering. It also provides robust support for producing publication-quality data plots. A large amount of 3rd-party packages are available, greatly increasing its breadth and scope.