Inference of Multiscale graphical models with neighborhood selection approach. The method is based on solving a convex optimization problem combining a Lasso and fused-group Lasso penalties. This allows to infer simultaneously a conditional independence graph and a clustering partition. The optimization is based on the Continuation with Nesterov smoothing in a Shrinkage-Thresholding Algorithm solver (Hadj-Selem et al. 2018) <doi:10.1109/TMI.2018.2829802> implemented in python.

This package provides a Software Development Kit for working with Nixtla''s TimeGPT', a foundation model for time series forecasting. API is an acronym for application programming interface'; this package allows users to interact with TimeGPT via the API'. You can set and validate API keys and generate forecasts via API calls. It is compatible with tsibble and base R. For more details visit <https://docs.nixtla.io/>.

The openMSE package is designed for building operating models, doing simulation modelling and management strategy evaluation for fisheries. openMSE is an umbrella package for the MSEtool (Management Strategy Evaluation toolkit), DLMtool (Data-Limited Methods toolkit), and SAMtool (Stock Assessment Methods toolkit) packages. By loading and installing openMSE', users have access to the full functionality contained within these packages. Learn more about openMSE at <https://openmse.com/>.

This package implements a range of facilities for post-hoc analysis and summarizing linear models, generalized linear models and generalized linear mixed models, including grouping and clustering via pairwise comparisons using graph representations and efficient algorithms for finding maximal cliques of a graph. Includes also non-parametric toos for post-hoc analysis. It has S3 methods for printing summarizing, and producing plots, line and barplots suitable for post-hoc analyses.

An R implementation of quality controlâ based robust LOESS(local polynomial regression fitting) signal correction for metabolomics data analysis, described in Dunn, W., Broadhurst, D., Begley, P. et al. (2011) <doi:10.1038/nprot.2011.335>. The optimisation of LOESS's span parameter using generalized cross-validation (GCV) is provided as an option. In addition to signal correction, qcrlscR includes some utility functions like batch shifting and data filtering.

Presents an explanatory animation of normal quantile-quantile plots based on a water-filling analogy. The animation presents a normal QQ plot as the parametric plot of the water levels in vases defined by two distributions. The distributions decorate the axes in the normal QQ plot and are optionally shown as vases adjacent to the plot. The package draws QQ plots for several distributions, either as samples or continuous functions.

This data-driven phylogenetic comparative method fits stabilizing selection models to continuous trait data, building on the ouch methodology of Butler and King (2004) <doi:10.1086/426002>. The main functions fit a series of Hansen models using stepwise AIC, then identify cases of convergent evolution where multiple lineages have shifted to the same adaptive peak. For more information see Ingram and Mahler (2013) <doi:10.1111/2041-210X.12034>.

Data wrangling, pre-processing, and generating automated reports from Colombia's epidemiological surveillance system, SIVIGILA <https://portalsivigila.ins.gov.co/>. It provides a customizable R Markdown template for analysis and automatic generation of epidemiological reports that can be adapted to local, regional, and national contexts. This tool offers a standardized and reproducible workflow that helps to reduce manual labor and potential errors in report generation, improving their efficiency and consistency.

This tiny package contains one function smirnov() which calculates two scaled taxonomic coefficients, Txy (coefficient of similarity) and Txx (coefficient of originality). These two characteristics may be used for the analysis of similarities between any number of taxonomic groups, and also for assessing uniqueness of giving taxon. It is possible to use smirnov() output as a distance measure: convert it to distance by "as.dist(1 - smirnov(x))".

This package implements marginal structural models combined with a latent class growth analysis framework for assessing the causal effect of treatment trajectories. Based on the approach described in "Marginal Structural Models with Latent Class Growth Analysis of Treatment Trajectories" Diop, A., Sirois, C., Guertin, J.R., Schnitzer, M.E., Candas, B., Cossette, B., Poirier, P., Brophy, J., Mésidor, M., Blais, C. and Hamel, D., (2023) <doi:10.1177/09622802231202384>.

This package provides a collection of commonly used tools for animal movement and other tracking data. Variously distance, angle, bearing, distance-to, bearing-to and speed are provided for geographic data that can be used directly or within tidyverse syntax. Distances and bearings are calculated using modern geodesic methods as provided by Charles F. F. Karney (2013) <doi:10.1007/s00190-012-0578-z> via the geodist and geosphere packages.

Estimates heterogeneous treatment effects using tidy semantics on experimental or observational data. Methods are based on the doubly-robust learner of Kennedy (2023) <doi:10.1214/23-EJS2157>. You provide a simple recipe for what machine learning algorithms to use in estimating the nuisance functions and tidyhte will take care of cross-validation, estimation, model selection, diagnostics and construction of relevant quantities of interest about the variability of treatment effects.

There are two new network metrics, RWC (random walk centrality) and CBET (counting betweenness). Also available are the normalized versions of those metrics. These measures of centrality and betweenness are particularly useful for the analysis of very dense weighted networks which include loops. Traditional measures do not work as well for those network characteristics. The main reference is DePaolis at al (2022) <doi:10.1007/s41109-022-00519-2>.

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of whole blood, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

This package implements various estimators of entropy, such as the shrinkage estimator by Hausser and Strimmer, the maximum likelihood and the Millow-Madow estimator, various Bayesian estimators, and the Chao-Shen estimator. It also offers an R interface to the NSB estimator. Furthermore, it provides functions for estimating Kullback-Leibler divergence, chi-squared, mutual information, and chi-squared statistic of independence. In addition there are functions for discretizing continuous random variables.

This package provides a system for embedded scientific computing and reproducible research with R. The OpenCPU server exposes a simple but powerful HTTP API for RPC and data interchange with R. This provides a reliable and scalable foundation for statistical services or building R web applications. The OpenCPU server runs either as a single-user development server within the interactive R session, or as a multi-user stack based on Apache2.

This package provides the Open Source Geometry Engine (GEOS) as a C API that can be used to write high-performance C and C++ geometry operations using R as an interface. Headers are provided to make linking to and using these functions from C++ code as easy and as safe as possible. This package contains an internal copy of the GEOS library to guarantee the best possible consistency on multiple platforms.

Perform common useful JavaScript operations in Shiny apps that will greatly improve your apps without having to know any JavaScript. Examples include: hiding an element, disabling an input, resetting an input back to its original value, delaying code execution by a few seconds, and many more useful functions for both the end user and the developer. Shinyjs can also be used to easily call your own custom JavaScript functions from R.

This package is a collection of ANSI escape code related libraries enabling ANSI colorization and stylization of console output. Included in the library are the Code module, which defines ANSI codes as constants and methods, a Mixin module for including color methods, a Logger, a ProgressBar, and a String subclass. The library also includes a Terminal module which provides information about the current output device.

This package provides functions and command-line user interface to generate allocation sequence by response-adaptive randomization for clinical trials. The package currently supports two families of frequentist response-adaptive randomization procedures, Doubly Adaptive Biased Coin Design ('DBCD') and Sequential Estimation-adjusted Urn Model ('SEU'), for binary and normal endpoints. One-sided proportion (or mean) difference and Chi-square (or ANOVA') hypothesis testing methods are also available in the package to facilitate the inference for treatment effect. Additionally, the package provides comprehensive and efficient tools to allow one to evaluate and compare the performance of randomization procedures and tests based on various criteria. For example, plots for relationship among assumed treatment effects, sample size, and power are provided. Five allocation functions for DBCD and six addition rule functions for SEU are implemented to target allocations such as Neyman', Rosenberger Rosenberger et al. (2001) <doi:10.1111/j.0006-341X.2001.00909.x> and Urn allocations.

Download data from the Access to Opportunities Project (AOP)'. The aopdata package brings annual estimates of access to employment, health, education and social assistance services by transport mode, as well as data on the spatial distribution of population, jobs, health care, schools and social assistance facilities at a fine spatial resolution for all cities included in the project. More info on the AOP website <https://www.ipea.gov.br/acessooportunidades/en/>.

This package implements the Bayesian FDR control described by Newton et al. (2004), <doi:10.1093/biostatistics/5.2.155>. Allows optimisation and visualisation of expected error rates based on tail posterior probability tests. Based on code written by Catalina Vallejos for BASiCS, see Beyond comparisons of means: understanding changes in gene expression at the single-cell level Vallejos et al. (2016) <doi:10.1186/s13059-016-0930-3>.

This package provides a ggplot2 centric approach to bivariate mapping. This is a technique that maps two quantities simultaneously rather than the single value that most thematic maps display. The package provides a suite of tools for calculating breaks using multiple different approaches, a selection of palettes appropriate for bivariate mapping and scale functions for ggplot2 calls that adds those palettes to maps. Tools for creating bivariate legends are also included.

This package implements non-parametric analyses for clustered binary and multinomial data. The elements of the cluster are assumed exchangeable, and identical joint distribution (also known as marginal compatibility, or reproducibility) is assumed for clusters of different sizes. A trend test based on stochastic ordering is implemented. Szabo A, George EO. (2010) <doi:10.1093/biomet/asp077>; George EO, Cheon K, Yuan Y, Szabo A (2016) <doi:10.1093/biomet/asw009>.