Provide multinomial design methods under intersection-union test (IUT) and union-intersection test (UIT) scheme for Phase II trial. The design types include : Minimax (minimize the maximum sample size), Optimal (minimize the expected sample size), Admissible (minimize the Bayesian risk) and Maxpower (maximize the exact power level).
This package provides a set of functions for querying and parsing data from Solr (<https://solr.apache.org/>) endpoints (local and remote), including search, faceting', highlighting', stats', and more like this'. In addition, some functionality is included for creating, deleting, and updating documents in a Solr database'.
This package provides functions for creating and annotating a composite plot in ggplot2'. Offers background themes and shortcut plotting functions that produce figures that are appropriate for the format of scientific journals. Some methods are described in Min and Zhou (2021) <doi:10.3389/fgene.2021.802894>.
Latent repeated measures ANOVA (L-RM-ANOVA) is a structural equation modeling based alternative to traditional repeated measures ANOVA. L-RM-ANOVA extends the latent growth components approach by Mayer et al. (2012) <doi:10.1080/10705511.2012.713242> and introduces latent variables to repeated measures analysis.
Helps the R users to get data from Tushare Pro'<https://tushare.pro>. Tushare Pro is a platform as well as a community with a lot of staffs working in financial area. We support financial data such as stock price, financial report statements and digital coins data.
This package provides a tidy workflow for generating, estimating, reporting, and plotting structural equation models using lavaan', OpenMx
', or Mplus'. Throughout this workflow, elements of syntax, results, and graphs are represented as tidy data, making them easy to customize. Includes functionality to estimate latent class analyses.
Longitudinal data offers insights into population changes over time but often requires a flexible structure, especially with varying follow-up intervals. Panel data is one way to store such records, though it adds complexity to analysis. The tvtools package for R simplifies exploring and analyzing panel data.
Uniform sampling of Directed Acyclic Graphs (DAG) using exact enumeration by relating each DAG to a sequence of outpoints (nodes with no incoming edges) and then to a composition of integers as suggested by Kuipers, J. and Moffa, G. (2015) <doi:10.1007/s11222-013-9428-y>.
Select data analysis plots, under a standardized calling interface implemented on top of ggplot2 and plotly'. Plots of interest include: ROC', gain curve, scatter plot with marginal distributions, conditioned scatter plot with marginal densities, box and stem with matching theoretical distribution, and density with matching theoretical distribution.
This package provides extra utilities for well-known formats in the wk package that are outside the scope of that package. Utilities to parse coordinates from data frames, plot well-known geometry vectors, extract meta information from well-known geometry vectors, and calculate bounding boxes are provided.
dStruct
identifies differentially reactive regions from RNA structurome profiling data. dStruct
is compatible with a broad range of structurome profiling technologies, e.g., SHAPE-MaP
, DMS-MaPseq
, Structure-Seq, SHAPE-Seq, etc. See Choudhary et al., Genome Biology, 2019 for the underlying method.
EpiTxDb
facilitates the storage of epitranscriptomic information. More specifically, it can keep track of modification identity, position, the enzyme for introducing it on the RNA, a specifier which determines the position on the RNA to be modified and the literature references each modification is associated with.
To classify Helicobacter pylori genomes according to genetic distance from nine reference populations. The nine reference populations are hpgpAfrica
, hpgpAfrica-distant
, hpgpAfroamerica
, hpgpEuroamerica
, hpgpMediterranea
, hpgpEurope
, hpgpEurasia
, hpgpAsia
, and hpgpAklavik86-like
. The vertex populations are Africa, Europe and Asia.
This package implements the spatially aware library size normalisation algorithm, SpaNorm
. SpaNorm
normalises out library size effects while retaining biology through the modelling of smooth functions for each effect. Normalisation is performed in a gene- and cell-/spot- specific manner, yielding library size adjusted data.
The two main functions in the package are pairwiseAlignment
and stringDist
. The former solves (Needleman-Wunsch) global alignment, (Smith-Waterman) local alignment, and (ends-free) overlap alignment problems. The latter computes the Levenshtein edit distance or pairwise alignment score matrix for a set of strings.
This package provides computationally efficient tools related to the multivariate normal and Student's t distributions. The main functionalities are: simulating multivariate random vectors, evaluating multivariate normal or Student's t densities and Mahalanobis distances. These tools are developed using C++ code and of the OpenMP API.
This package provides an R implementation of the Octave package signal
, containing a variety of signal processing tools, such as signal generation and measurement, correlation and convolution, filtering, filter design, filter analysis and conversion, power spectrum analysis, system identification, decimation and sample rate change, and windowing.
This package provides a set of restricted permutation designs for freely exchangeable, line transects (time series), spatial grid designs and permutation of blocks (groups of samples). permute
also allows split-plot designs, in which the whole-plots or split-plots or both can be freely exchangeable.
Define distribution families and fit them to interval-censored and interval-truncated data, where the truncation bounds may depend on the individual observation. The defined distributions feature density, probability, sampling and fitting methods as well as efficient implementations of the log-density log f(x) and log-probability log P(x0 <= X <= x1) for use in TensorFlow
neural networks via the tensorflow package. Allows training parametric neural networks on interval-censored and interval-truncated data with flexible parameterization. Applications include Claims Development in Non-Life Insurance, e.g. modelling reporting delay distributions from incomplete data, see Bücher, Rosenstock (2022) <doi:10.1007/s13385-022-00314-4>.
This package provides an easy to use unified interface for creating validation plots for any model. The auditor helps to avoid repetitive work consisting of writing code needed to create residual plots. This visualizations allow to asses and compare the goodness of fit, performance, and similarity of models.
This package provides tools for assessing exotic species contributions to landscape homogeneity using average pairwise Jaccard similarity and an analytical approximation derived in Harris et al. (2011, "Occupancy is nine-tenths of the law," The American Naturalist). Also includes a randomization method for assessing sources of model error.
This package provides a toolkit to perform cross-species analysis based on scRNA-seq
data. This package contains 5 main features. (1) identify Markers in each cluster. (2) Cell type annotation (3) identify conserved markers. (4) identify conserved cell types. (5) identify conserved modules of regulatory networks.
This package contains functions to detect and visualise periods of climate sensitivity (climate windows) for a given biological response. Please see van de Pol et al. (2016) <doi:10.1111/2041-210X.12590> and Bailey and van de Pol (2016) <doi:10.1371/journal.pone.0167980> for details.
To calculate the AQI (Air Quality Index) from pollutant concentration data. O3, PM2.5, PM10, CO, SO2, and NO2 are available currently. The method can be referenced at Environmental Protection Agency, United States as follows: EPA (2016) <https://www3.epa.gov/airnow/aqi-technical-assistance-document-may2016.pdf>.