This package provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.

Methods-first tooling for reproducing and extending the partial least squares regression studies on incomplete data described in Nengsih et al. (2019) <doi:10.1515/sagmb-2018-0059>. The package provides simulation helpers, missingness generators, imputation wrappers, component-selection utilities, real-data diagnostics, and reproducible study orchestration for Nonlinear Iterative Partial Least Squares (NIPALS)-Partial Least Squares (PLS) workflows.

This package performs Monte Carlo hypothesis tests, allowing a couple of different sequential stopping boundaries. For example, a truncated sequential probability ratio test boundary (Fay, Kim and Hachey, 2007 <DOI:10.1198/106186007X257025>) and a boundary proposed by Besag and Clifford, 1991 <DOI:10.1093/biomet/78.2.301>. Gives valid p-values and confidence intervals on p-values.

Many tools for calculating network, node, or tie marks, measures, motifs and memberships of many different types of networks. Marks identify structural positions, measures quantify network properties, memberships classify nodes into groups, and motifs tabulate substructure participation. All functions operate with all classes of network data covered in manynet', and on directed, undirected, multiplex, multimodal, signed, and other networks.

This package provides a method for fitting the entire regularization path of the principal components lasso for linear and logistic regression models. The algorithm uses cyclic coordinate descent in a path-wise fashion. See URL below for more information on the algorithm. See Tay, K., Friedman, J. ,Tibshirani, R., (2014) Principal component-guided sparse regression <arXiv:1810.04651>.

Fast tools for fitting sparse generalized linear models with convex penalties (lasso) and concave penalties (smoothly clipped absolute deviation and minimax concave penalty). Computation uses multi-stage convex relaxation and pathwise coordinate optimization with warm starts, active-set updates, and screening rules. Core solvers are implemented in C++, and coefficient paths are stored as sparse matrices for memory efficiency.

This package provides functions for estimating the potential dispersal of tree species using regeneration densities and dispersal distances to nearest seed trees. A quantile regression is implemented to determine the dispersal potential. Spatial prediction can be used to identify natural regeneration potential for forest restoration as described in Axer et al (2021) <doi:10.1016/j.foreco.2020.118802>.

These functions were developed within SECFISH project (Strengthening regional cooperation in the area of fisheries data collection-Socio-economic data collection for fisheries, aquaculture and the processing industry at EU level). They are aimed at identifying correlations between costs and transversal variables by metier using individual vessel data and for disaggregating variable costs from fleet segment to metier level.

The SAWNUTI algorithm performs sequence comparison for finite sequences of discrete events with non-uniform time intervals. Further description of the algorithm can be found in the paper: A. Murph, A. Flynt, B. R. King (2021). Comparing finite sequences of discrete events with non-uniform time intervals, Sequential Analysis, 40(3), 291-313. <doi:10.1080/07474946.2021.1940491>.

This package implements stacked elastic net regression (Rauschenberger 2021 <doi:10.1093/bioinformatics/btaa535>). The elastic net generalises ridge and lasso regularisation (Zou 2005 <doi:10.1111/j.1467-9868.2005.00503.x>). Instead of fixing or tuning the mixing parameter alpha, we combine multiple alpha by stacked generalisation (Wolpert 1992 <doi:10.1016/S0893-6080(05)80023-1>).

R is a language and environment for statistical computing and graphics. It provides a variety of statistical techniques, such as linear and nonlinear modeling, classical statistical tests, time-series analysis, classification and clustering. It also provides robust support for producing publication-quality data plots. A large amount of 3rd-party packages are available, greatly increasing its breadth and scope.

The GNU Privacy Guard is a complete implementation of the OpenPGP standard. It is used to encrypt and sign data and communication. It features powerful key management and the ability to access public key servers. It includes several libraries: libassuan (IPC between GnuPG components), libgpg-error (centralized GnuPG error values), and libskba (working with X.509 certificates and CMS data).

Balancing quasi-experimental field research for effects of covariates is fundamental for drawing causal inference. Propensity Score Matching deals with this issue but current techniques are restricted to binary treatment variables. Moreover, they provide several solutions without providing a comprehensive framework on choosing the best model. The MAGMA R-package addresses these restrictions by offering nearest neighbor matching for two to four groups. It also includes the option to match data of a 2x2 design. In addition, MAGMA includes a framework for evaluating the post-matching balance. The package includes functions for the matching process and matching reporting. We provide a tutorial on MAGMA as vignette. More information on MAGMA can be found in Feuchter, M. D., Urban, J., Scherrer V., Breit, M. L., and Preckel F. (2022) <https://osf.io/p47nc/>.

The affyPLM provides a package that extends and improves the functionality of the base affy package. For speeding up the runs, it includes routines that make heavy use of compiled code. The central focus is on implementation of methods for fitting probe-level models and tools using these models. PLM based quality assessment tools are also provided.

This package provides estimators for multinomial logit models in their conditional logit and baseline logit variants, with or without random effects, with or without overdispersion. Random effects models are estimated using the PQL technique (based on a Laplace approximation) or the MQL technique (based on a Solomon-Cox approximation). Estimates should be treated with caution if the group sizes are small.

Ggplot2 is an implementation of the grammar of graphics in R. It combines the advantages of both base and lattice graphics: conditioning and shared axes are handled automatically, and you can still build up a plot step by step from multiple data sources. It also implements a sophisticated multidimensional conditioning system and a consistent interface to map data to aesthetic attributes.

This package provides the Molecular Signatures Database (MSigDB) gene sets typically used with the Gene Set Enrichment Analysis (GSEA) software in a standard R data frame with key-value pairs. Included are the original human gene symbols and Entrez IDs as well as the equivalents for various frequently studied model organisms such as mouse, rat, pig, fly, and yeast.

RadeonTop monitors resource consumption on supported AMD Radeon Graphics Processing Units (GPUs), either in real time as bar graphs on a terminal or saved to a file for further processing. It measures both the activity of the GPU as a whole, which is also accurate during OpenCL computations, as well as separate component statistics that are only meaningful under OpenGL graphics workloads.

This package provides a collection of algorithms and functions to aid statistical modeling. It includes growth curve comparisons, limiting dilution analysis (aka ELDA), mixed linear models, heteroscedastic regression, inverse-Gaussian probability calculations, Gauss quadrature and a secure convergence algorithm for nonlinear models. It also includes advanced generalized linear model functions that implement secure convergence, dispersion modeling and Tweedie power-law families.

Linear and nonlinear regression analysis common in agricultural science articles (Archontoulis & Miguez (2015). <doi:10.2134/agronj2012.0506>). The package includes polynomial, exponential, gaussian, logistic, logarithmic, segmented, non-parametric models, among others. The functions return the model coefficients and their respective p values, coefficient of determination, root mean square error, AIC, BIC, as well as graphs with the equations automatically.

When many possible multiplier method estimates of a target population are available, a weighted sum of estimates from each back-calculated path can be achieved with this package. Variance-minimizing weights are used and with any admissible tree-structured data. The methodological basis used to create this package can be found in Flynn (2023) <http://hdl.handle.net/2429/86174>.

Fits random effects models for multi-level/high-cardinality factors using credibility theory (Buhlmann-Straub for single-level, Jewell for hierarchical structures), GLM extensions following Ohlsson (2008) <doi:10.1080/03461230701878612>, or Tweedie generalized linear mixed models. Provides functions for model fitting, visualization, and prediction. See Campo, B.D.C. and Antonio, K. (2023) <doi:10.1080/03461238.2022.2161413>.

Routines for re-scaling isotope maps using known-origin tissue isotope data, assigning origin of unknown samples, and summarizing and assessing assignment results. Methods are adapted from Wunder (2010, in ISBN:9789048133536) and Vander Zanden, H. B. et al. (2014) <doi:10.1111/2041-210X.12229> as described in Ma, C. et al. (2020) <doi:10.1111/2041-210X.13426>.

This package provides color palettes based on crayon colors since the early 1900s. Colors are based on various crayon colors, sets, and promotional palettes, most of which can be found at <https://en.wikipedia.org/wiki/List_of_Crayola_crayon_colors>. All palettes are discrete palettes and are not necessarily color-blind friendly. Provides scales for ggplot2 for discrete coloring.