Perform a Visual Predictive Check (VPC), while accounting for stratification, censoring, and prediction correction. Using piping from magrittr', the intuitive syntax gives users a flexible and powerful method to generate VPCs using both traditional binning and a new binless approach Jamsen et al. (2018) <doi:10.1002/psp4.12319> with Additive Quantile Regression (AQR) and Locally Estimated Scatterplot Smoothing (LOESS) prediction correction.

Up-and-Down (UD) is the most popular design approach for dose-finding, but it has been severely under-served by the statistical and computing communities. This is the first package that comprehensively addresses UD's needs. Recent applied UD tutorial: Oron et al., 2022 <doi:10.1097/ALN.0000000000004282>. Recent methodological overview: Oron and Flournoy, 2024 <doi:10.51387/24-NEJSDS74>.

Simulates and evaluates stochastic scenarios of death and lapse events in life reinsurance contracts with profit commissions. The methodology builds on materials published by the Institute of Actuaries of Japan <https://www.actuaries.jp/examin/textbook/pdf/modeling.pdf>. A paper describing the detailed algorithms will be published by the author within a few months after the initial release of this package.

The renewal Hawkes (RHawkes) process (Wheatley, Filimonov, and Sornette, 2016 <doi:10.1016/j.csda.2015.08.007>) is an extension to the classical Hawkes self-exciting point process widely used in the modelling of clustered event sequence data. This package provides functions to simulate the RHawkes process with a given immigrant hazard rate function and offspring birth time density function, to compute the exact likelihood of a RHawkes process using the recursive algorithm proposed by Chen and Stindl (2018) <doi:10.1080/10618600.2017.1341324>, to compute the Rosenblatt residuals for goodness-of-fit assessment, and to predict future event times based on observed event times up to a given time. A function implementing the linear time RHawkes process likelihood approximation algorithm proposed in Stindl and Chen (2021) <doi:10.1007/s11222-021-10002-0> is also included.

Visualizing crystal structures and selected area electron diffraction (SAED) patterns. It provides functions cry_demo() and dp_demo() to load a file in CIF (Crystallographic Information Framework) formats and display crystal structures and electron diffraction patterns. The function dp_demo() also performs simple simulation of powder X-ray diffraction (PXRD) patterns, and the results can be saved to a file in the working directory. The package has been tested on several platforms, including Linux on Crostini with a Coreâ ¢ m3-8100Y Chromebook, I found that even on this low-powered platform, the performance was acceptable. T. Hanashima (2001) <https://www2.kek.jp/imss/pf/tools/sasaki/sinram/sinram.html> Todd Helmenstine (2019) <https://sciencenotes.org/molecule-atom-colors-cpk-colors/> Wikipedia contributors (2023) <https://en.wikipedia.org/w/index.php?title=Atomic_radius&oldid=1179864711>.

The bayNorm package is used for normalizing single-cell RNA-seq data. The main function is bayNorm, which is a wrapper function for gene specific prior parameter estimation and normalization. The input is a matrix of scRNA-seq data with rows different genes and columns different cells. The output is either point estimates from posterior (2D array) or samples from posterior (3D array).

IONiseR provides tools for the quality assessment of Oxford Nanopore MinION data. It extracts summary statistics from a set of fast5 files and can be used either before or after base calling. In addition to standard summaries of the read-types produced, it provides a number of plots for visualising metrics relative to experiment run time or spatially over the surface of a flowcell.

This package provides tools for normalizing and analyzing of GeneChip Mapping 100K and 500K Set. Affymetrix GeneChip Human Mapping 100K and 500K Set allows the DNA copy number mea- surement of respectively 2× 50K and 2× 250K SNPs along the genome. Their high density allows a precise localization of genomic alterations and makes them a powerful tool for cancer and copy number polymorphism study.

This package provides tools for defensive programming. It is inspired by purrr mappers and based on rlang. Attempt extends and facilitates defensive programming by providing a consistent grammar, and a set of functions for common tests and conditions. Attempt only depends on rlang, and focuses on speed, so it can be integrated with other functions and used in the data analysis.

The two main functionalities of this package are creating mock objects (functions) and selectively intercepting calls to a given function that originate in some other function. It can be used with any testing framework available for R. Mock objects can be injected with either this package's own stub function or a similar with_mock facility present in the testthat package.

This package provides a GUI interface for the DAPAR package. The package Prostar (Proteomics statistical analysis with R) is a Bioconductor distributed R package which provides all the necessary functions to analyze quantitative data from label-free proteomics experiments. Contrarily to most other similar R packages, it is endowed with rich and user-friendly graphical interfaces, so that no programming skill is required.

This package performs a gene expression data analysis to detect condition-specific genes. Such genes are significantly up- or down-regulated in a small number of conditions. It does so by fitting a mixture of normal distributions to the expression values. Conditions can be environmental conditions, different tissues, organs or any other sources that you wish to compare in terms of gene expression.

Helps users standardise data to the Darwin Core Standard, a global data standard to store, document, and share biodiversity data like species occurrence records. The package provides tools to manipulate data to conform with, and check validity against, the Darwin Core Standard. Using corella allows users to verify that their data can be used to build Darwin Core Archives using the galaxias package.

This package provides tools for advanced analysis of continuous glucose monitoring (CGM) time-series, implementing GRID (Glucose Rate Increase Detector) and GRID-based algorithms for postprandial peak detection, and detection of hypoglycemic and hyperglycemic episodes (Levels 1/2/Extended) aligned with international consensus CGM metrics. Core algorithms are implemented in optimized C++ using Rcpp to provide accurate and fast analysis on large datasets.

This package implements cointegration/co-trending rank selection algorithm in Guo and Shintani (2013) "Consistent co-trending rank selection when both stochastic and nonlinear deterministic trends are present". The Econometrics Journal 16: 473-483 <doi:10.1111/j.1368-423X.2012.00392.x>. Numbered examples correspond to Feb 2011 preprint <http://www.fas.nus.edu.sg/ecs/events/seminar/seminar-papers/05Apr11.pdf>.

Discretization-based random sampling algorithm that is useful for a complex model in high dimension is implemented. The normalizing constant of a target distribution is not needed. Posterior summaries are compared with those by OpenBUGS'. The method is described: Wang and Lee (2014) <doi:10.1016/j.csda.2013.06.011> and exercised in Lee (2009) <http://hdl.handle.net/1993/21352>.

The concept of Essential Biodiversity Variables (EBV, <https://geobon.org/ebvs/what-are-ebvs/>) comes with a data structure based on the Network Common Data Form (netCDF). The ebvcube R package provides functionality to easily create, access and visualise this data. The EBV netCDFs can be downloaded from the EBV Data Portal: Christian Langer/ iDiv (2020) <https://portal.geobon.org/>.

Create, visualize, and test fast-and-frugal decision trees (FFTs) using the algorithms and methods described by Phillips, Neth, Woike & Gaissmaier (2017), <doi:10.1017/S1930297500006239>. FFTs are simple and transparent decision trees for solving binary classification problems. FFTs can be preferable to more complex algorithms because they require very little information, are easy to understand and communicate, and are robust against overfitting.

Creates, manipulates, and evaluates hemodynamic response functions and event-related regressors for functional magnetic resonance imaging data analysis. Supports multiple basis sets including Canonical, Gamma, Gaussian, B-spline, and Fourier bases. Features decorators for time-shifting and blocking, and efficient convolution algorithms for regressor construction. Methods are based on standard fMRI analysis techniques as described in Jezzard et al. (2001, ISBN:9780192630711).

Flexible framework for specifying survival distributions through their hazard (failure rate) functions. Define arbitrary time-varying hazard functions to model complex failure patterns including bathtub curves, proportional hazards with covariates, and other non-standard hazard behaviors. Provides automatic computation of survival, CDF, PDF, quantiles, and sampling. Implements the likelihood model interface for maximum likelihood estimation with right-censored and left-censored survival data.

This package creates structured R and Quarto projects with a consistent directory layout: scripts in R/, analysis documents in analysis/, and web assets in www/. The primary entry point, init(), downloads the latest template from a companion GitHub repository so that project structure evolves independently of package releases. Supports persistent author metadata and Quarto brand configuration that carry across projects automatically.

Finds adaptive strategies for sequential symmetric games using a genetic algorithm. Currently, any symmetric two by two matrix is allowed, and strategies can remember the history of an opponent's play from the previous three rounds of moves in iterated interactions between players. The genetic algorithm returns a list of adaptive strategies given payoffs, and the mean fitness of strategies in each generation.

Estimating heterogeneous treatment effects with tree-based machine learning algorithms and visualizing estimated results in flexible and presentation-ready ways. For more information, see Brand, Xu, Koch, and Geraldo (2021) <doi:10.1177/0081175021993503>. Our current package first started as a fork of the causalTree package on GitHub and we greatly appreciate the authors for their extremely useful and free package.

An implementation of the induced smoothing (IS) idea to lasso regularization models to allow estimation and inference on the model coefficients (currently hypothesis testing only). Linear, logistic, Poisson and gamma regressions with several link functions are implemented. The algorithm is described in the original paper; see <doi:10.1177/0962280219842890> and discussed in a tutorial <doi:10.13140/RG.2.2.16360.11521>.