This package provides convenient access to the German modification of the International Classification of Diagnoses, 10th revision (ICD-10-GM). It provides functionality to aid in the identification, specification and historisation of ICD-10 codes. Its intended use is the analysis of routinely collected data in the context of epidemiology, medical research and health services research. The underlying metadata are released by the German Institute for Medical Documentation and Information <https://www.dimdi.de>, and are redistributed in accordance with their license.

This package implements k-means like blockmodeling of one-mode and linked networks as presented in Žiberna (2020) <doi:10.1016/j.socnet.2019.10.006>. The development of this package is financially supported by the Slovenian Research Agency (<https://www.arrs.si/>) within the research programs P5-0168 and the research projects J7-8279 (Blockmodeling multilevel and temporal networks) and J5-2557 (Comparison and evaluation of different approaches to blockmodeling dynamic networks by simulations with application to Slovenian co-authorship networks).

This package provides a joint latent class model where a hierarchical structure exists, with an interaction between female and male partners of a couple. A Bayesian perspective to inference and Markov chain Monte Carlo algorithms to obtain posterior estimates of model parameters. The reference paper is: Beom Seuk Hwang, Zhen Chen, Germaine M.Buck Louis, Paul S. Albert, (2018) "A Bayesian multi-dimensional couple-based latent risk model with an application to infertility". Biometrics, 75, 315-325. <doi:10.1111/biom.12972>.

This package creates and runs Bayesian mixing models to analyze biological tracer data (i.e. stable isotopes, fatty acids), which estimate the proportions of source (prey) contributions to a mixture (consumer). MixSIAR is not one model, but a framework that allows a user to create a mixing model based on their data structure and research questions, via options for fixed/ random effects, source data types, priors, and error terms. MixSIAR incorporates several years of advances since MixSIR and SIAR'.

This package performs robust cluster analysis allowing for outliers and noise that cannot be fitted by any cluster. The data are modelled by a mixture of Gaussian distributions and a noise component, which is an improper uniform distribution covering the whole Euclidean space. Parameters are estimated by (pseudo) maximum likelihood. This is fitted by a EM-type algorithm. See Coretto and Hennig (2016) <doi:10.1080/01621459.2015.1100996>, and Coretto and Hennig (2017) <https://jmlr.org/papers/v18/16-382.html>.

Numerical integration of continuously differentiable functions f(x,y) over simple closed polygonal domains. The following cubature methods are implemented: product Gauss cubature (Sommariva and Vianello, 2007, <doi:10.1007/s10543-007-0131-2>), the simple two-dimensional midpoint rule (wrapping spatstat.geom functions), and adaptive cubature for radially symmetric functions via line integrate() along the polygon boundary (Meyer and Held, 2014, <doi:10.1214/14-AOAS743>, Supplement B). For simple integration along the axes, the cubature package is more appropriate.

This package provides deep learning models for right-censored survival data using the torch backend. Supports multiple loss functions, including Cox partial likelihood, L2-penalized Cox, time-dependent Cox, and accelerated failure time (AFT) loss. Offers a formula-based interface, built-in support for cross-validation, hyperparameter tuning, survival curve plotting, and evaluation metrics such as the C-index, Brier score, and integrated Brier score. For methodological details, see Kvamme et al. (2019) <https://www.jmlr.org/papers/v20/18-424.html>.

Aims to quantify time intensity data by using sigmoidal and double sigmoidal curves. It fits straight lines, sigmoidal, and double sigmoidal curves on to time vs intensity data. Then all the fits are used to make decision on which model best describes the data. This method was first developed in the context of single-cell viral growth analysis (for details, see Caglar et al. (2018) <doi:10.7717/peerj.4251>), and the package name stands for "SIngle CEll Growth Analysis in R".

This package provides functions to model and forecast crop yields using a spatial temporal conditional copula approach. The package incorporates extreme weather covariates and Bayesian Structural Time Series models to analyze crop yield dependencies across multiple regions. Includes tools for fitting, simulating, and visualizing results. This method build upon established R packages, including Hofert et al'. (2025) <doi:10.32614/CRAN.package.copula>, Scott (2024) <doi:10.32614/CRAN.package.bsts>, and Stephenson et al'. (2024) <doi:10.32614/CRAN.package.evd>.

The Seqinfo class stores the names, lengths, circularity flags, and genomes for a particular collection of sequences. These sequences are typically the chromosomes and/or scaffolds of a specific genome assembly of a given organism. Seqinfo objects are rarely used as standalone objects. Instead, they are used as part of higher-level objects to represent their seqinfo() component. Examples of such higher-level objects are GRanges, RangedSummarizedExperiment, VCF, GAlignments, etc… defined in other Bioconductor infrastructure packages.

When testing multiple hypotheses simultaneously, this package provides functionality to calculate a lower bound for the number of correct rejections (as a function of the number of rejected hypotheses), which holds simultaneously -with high probability- for all possible number of rejections. As a special case, a lower bound for the total number of false null hypotheses can be inferred. Dependent test statistics can be handled for multiple tests of associations. For independent test statistics, it is sufficient to provide a list of p-values.

This package provides userspace components for the InfiniBand subsystem of the Linux kernel. Specifically it contains userspace libraries for the following device nodes:

1. /dev/infiniband/uverbsX (libibverbs)

2. /dev/infiniband/rdma_cm (librdmacm)

3. /dev/infiniband/umadX (libibumad)

The following service daemons are also provided:

1. srp_daemon (for the ib_srp kernel module)

2. iwpmd (for iWARP kernel providers)

3. ibacm (for InfiniBand communication management assistant)

COMPASS is a statistical framework that enables unbiased analysis of antigen-specific T-cell subsets. COMPASS uses a Bayesian hierarchical framework to model all observed cell-subsets and select the most likely to be antigen-specific while regularizing the small cell counts that often arise in multi-parameter space. The model provides a posterior probability of specificity for each cell subset and each sample, which can be used to profile a subject's immune response to external stimuli such as infection or vaccination.

This package implements the deflist class, a read-only list-like object that accesses its elements via a function. The deflist class can be used to model deferred access to data or computations by routing indexed list access to a function. This approach is particularly useful when sequential list-like access to data is required but holding all the data in memory at once is not feasible. The package also provides utilities for memoisation and caching to optimize access to frequently requested elements.

This package provides various statistical methods for evaluating heterogeneous treatment effects (HTE) in randomized experiments. The package includes tools to estimate uniform confidence bands for estimation of the group average treatment effect sorted by generic machine learning algorithms (GATES). It also provides the tools to identify a subgroup of individuals who are likely to benefit from a treatment the most "exceptional responders" or those who are harmed by it. Detailed reference in Imai and Li (2023) <doi:10.48550/arXiv.2310.07973>.

This package implements the Factor-Augmented Clustering Tree (FACT) algorithm for clustering time series data. The method constructs a classification tree where splits are determined by covariates, and the splitting criterion is based on a group factor model representation of the time series within each node. Both threshold-based and permutation-based tests are supported for splitting decisions, with an option for parallel computation. For methodological details, see Hu, Li, Luo, and Wang (2025, in preparation), Factor-Augmented Clustering Tree for Time Series.

Regression using GMDH algorithms from Prof. Alexey G. Ivakhnenko. Group Method of Data Handling (GMDH), or polynomial neural networks, is a family of inductive algorithms that performs gradually complicated polynomial models and selecting the best solution by an external criterion. In other words, inductive GMDH algorithms give possibility finding automatically interrelations in data, and selecting an optimal structure of model or network. The package includes GMDH Combinatorial, GMDH MIA (Multilayered Iterative Algorithm), GMDH GIA (Generalized Iterative Algorithm) and GMDH Combinatorial with Active Neurons.

This package provides a handy collection of utility functions designed to aid in package development, plotting and scientific research. Package development functionalities includes among others tools such as cross-referencing package imports with the description file, analysis of redundant package imports, editing of the description file and the creation of package badges for GitHub. Some of the other functionalities include automatic package installation and loading, plotting points without overlap, creating nice breaks for plots, overview tables and many more handy utility functions.

An extended version of the nonparametric Bayesian monotonic regression procedure described in Saarela & Arjas (2011) <DOI:10.1111/j.1467-9469.2010.00716.x>, allowing for multiple additive monotonic components in the linear predictor, and time-to-event outcomes through case-base sampling. The extension and its applications, including estimation of absolute risks, are described in Saarela & Arjas (2015) <DOI:10.1111/sjos.12125>. The package also implements the nonparametric ordinal regression model described in Saarela, Rohrbeck & Arjas <DOI:10.1214/22-BA1310>.

Compute detailed and aggregated performance spectrum for event data. The detailed performance spectrum describes the event data in terms of segments, where the performance of each segment is measured and plotted for any occurrences of this segment over time and can be classified, e.g., regarding the overall population. The aggregated performance spectrum visualises the amount of cases of particular performance over time. Denisov, V., Fahland, D., & van der Aalst, W. M. P. (2018) <doi:10.1007/978-3-319-98648-7_9>.

This package provides tools for statistical testing of correlation coefficients through robust permutation method and large sample approximation method. Tailored to different types of correlation coefficients including Pearson correlation coefficient, weighted Pearson correlation coefficient, Spearman correlation coefficient, and Lin's concordance correlation coefficient.The robust permutation test controls type I error under general scenarios when sample size is small and two variables are dependent but uncorrelated. The large sample approximation test generally controls type I error when the sample size is large (>200).

Shadow Document Object Model is a web standard that offers component style and markup encapsulation. It is a critically important piece of the Web Components story as it ensures that a component will work in any environment even if other CSS or JavaScript is at play on the page. Custom HTML tags can't be directly identified with selenium tools, because Selenium doesn't provide any way to deal with shadow elements. Using this plugin you can handle any custom HTML tags.

BANDITS is a Bayesian hierarchical model for detecting differential splicing of genes and transcripts, via DTU (differential transcript usage), between two or more conditions. The method uses a Bayesian hierarchical framework, which allows for sample specific proportions in a Dirichlet-Multinomial model, and samples the allocation of fragments to the transcripts. Parameters are inferred via MCMC (Markov chain Monte Carlo) techniques and a DTU test is performed via a multivariate Wald test on the posterior densities for the average relative abundance of transcripts.

This package provides support for the foreach looping construct. foreach is an idiom that allows for iterating over elements in a collection, without the use of an explicit loop counter. This package in particular is intended to be used for its return value, rather than for its side effects. In that sense, it is similar to the standard lapply function, but doesn't require the evaluation of a function. Using foreach without side effects also facilitates executing the loop in parallel.