This package provides functions aiming to facilitate the analysis of the structure of animal acoustic signals in R'. warbleR makes use of the basic sound analysis tools from the packages tuneR and seewave', and offers new tools for exploring and quantifying acoustic signal structure. The package allows to organize and manipulate multiple sound files, create spectrograms of complete recordings or individual signals in different formats, run several measures of acoustic structure, and characterize different structural levels in acoustic signals (Araya-Salas et al 2016 <doi:10.1111/2041-210X.12624>).

This package provides a collection of functions designed for analyzing deconvolution of the bulk sample(s) using an atlas of reference omic signature profiles and a user-selected model. Users are given the option to create or extend a reference atlas and,also simulate the desired size of the bulk signature profile of the reference cell types. The package includes the cell-type-specific methylation atlas and, Illumina Epic B5 probe ids that can be used in deconvolution. Additionally, we included BSmeth2Probe, to make mapping WGBS data to their probe IDs easier.

This package implements importance sampling from the truncated multivariate normal using the Geweke-Hajivassiliou-Keane (GHK) simulator. Unlike Gibbs sampling which can get stuck in one truncation sub-region depending on initial values, this package allows truncation based on disjoint regions that are created by truncation of absolute values. The GHK algorithm uses simple Cholesky transformation followed by recursive simulation of univariate truncated normals hence there are also no convergence issues. Importance sample is returned along with sampling weights, based on which, one can calculate integrals over truncated regions for multivariate normals.

Contrast trees represent a new approach for assessing the accuracy of many types of machine learning estimates that are not amenable to standard (cross) validation methods; see "Contrast trees and distribution boosting", Jerome H. Friedman (2020) <doi:10.1073/pnas.1921562117>. In situations where inaccuracies are detected, boosted contrast trees can often improve performance. Functions are provided to to build such trees in addition to a special case, distribution boosting, an assumption free method for estimating the full probability distribution of an outcome variable given any set of joint input predictor variable values.

This package provides tools for estimating the Remaining Useful Life (RUL) of degrading systems using linear mixed-effects models and creating a health index. It supports both univariate and multivariate degradation signals. For multivariate inputs, the signals are merged into a univariate health index prior to modeling. Linear and exponential degradation trajectories are supported (the latter using a log transformation). Remaining Useful Life (RUL) distributions are estimated using Bayesian updating for new units, enabling on-site predictive maintenance. Based on the methodology of Liu and Huang (2016) <doi:10.1109/TASE.2014.2349733>.

Simplifies the creation, management, and updating of local databases using data extracted from Google Earth Engine ('GEE'). It integrates with GEE to store, aggregate, and process spatio-temporal data, leveraging SQLite for efficient, serverless storage. The geeLite package provides utilities for data transformation and supports real-time monitoring and analysis of geospatial features, making it suitable for researchers and practitioners in geospatial science. For details, see Kurbucz and Andrée (2025) "Building and Managing Local Databases from Google Earth Engine with the geeLite R Package" <https://hdl.handle.net/10986/43165>.

Uses an approach based on k-nearest neighbor information to sequentially detect change-points. Offers analytic approximations for false discovery control given user-specified average run length. Can be applied to any type of data (high-dimensional, non-Euclidean, etc.) as long as a reasonable similarity measure is available. See references (1) Chen, H. (2019) Sequential change-point detection based on nearest neighbors. The Annals of Statistics, 47(3):1381-1407. (2) Chu, L. and Chen, H. (2018) Sequential change-point detection for high-dimensional and non-Euclidean data <arXiv:1810.05973>.

Dependency-free, ultra fast calculation of geodesic distances. Includes the reference nanometre-accuracy geodesic distances of Karney (2013) <doi:10.1007/s00190-012-0578-z>, as used by the sf package, as well as Haversine and Vincenty distances. Default distance measure is the "Mapbox cheap ruler" which is generally more accurate than Haversine or Vincenty for distances out to a few hundred kilometres, and is considerably faster. The main function accepts one or two inputs in almost any generic rectangular form, and returns either matrices of pairwise distances, or vectors of sequential distances.

This package provides researchers and educators with easy-to-learn user friendly tools for calculating key spatial statistics and to apply simple as well as advanced methods of spatial analysis in real data. These include: Local Pearson and Geographically Weighted Pearson Correlation Coefficients, Spatial Inequality Measures (Gini, Spatial Gini, LQ, Focal LQ), Spatial Autocorrelation (Global and Local Moran's I), several Geographically Weighted Regression techniques and other Spatial Analysis tools (other geographically weighted statistics). This package also contains functions for measuring the significance of each statistic calculated, mainly based on Monte Carlo simulations.

Utilizing model-based clustering (unsupervised) for functional magnetic resonance imaging (fMRI) data. The developed methods (Chen and Maitra (2023) <doi:10.1002/hbm.26425>) include 2D and 3D clustering analyses (for p-values with voxel locations) and segmentation analyses (for p-values alone) for fMRI data where p-values indicate significant level of activation responding to stimulate of interesting. The analyses are mainly identifying active voxel/signal associated with normal brain behaviors. Analysis pipelines (R scripts) utilizing this package (see examples in inst/workflow/') is also implemented with high performance techniques.

Estimates one-inflated positive Poisson (OIPP) and one-inflated zero-truncated negative binomial (OIZTNB) regression models. A suite of ancillary statistical tools are also provided, including: estimation of positive Poisson (PP) and zero-truncated negative binomial (ZTNB) models; marginal effects and their standard errors; diagnostic likelihood ratio and Wald tests; plotting; predicted counts and expected responses; and random variate generation. The models and tools, as well as four applications, are shown in Godwin, R. T. (2024). "One-inflated zero-truncated count regression models" arXiv preprint <doi:10.48550/arXiv.2402.02272>.

This package provides Partial least squares Regression and various regular, sparse or kernel, techniques for fitting Cox models in high dimensional settings <doi:10.1093/bioinformatics/btu660>, Bastien, P., Bertrand, F., Meyer N., Maumy-Bertrand, M. (2015), Deviance residuals-based sparse PLS and sparse kernel PLS regression for censored data, Bioinformatics, 31(3):397-404. Cross validation criteria were studied in <doi:10.48550/arXiv.1810.02962>, Bertrand, F., Bastien, Ph. and Maumy-Bertrand, M. (2018), Cross validating extensions of kernel, sparse or regular partial least squares regression models to censored data.

Aims to utilize model-based clustering (unsupervised) for high dimensional and ultra large data, especially in a distributed manner. The code employs pbdMPI to perform a expectation-gathering-maximization algorithm for finite mixture Gaussian models. The unstructured dispersion matrices are assumed in the Gaussian models. The implementation is default in the single program multiple data programming model. The code can be executed through pbdMPI and MPI implementations such as OpenMPI and MPICH'. See the High Performance Statistical Computing website <https://snoweye.github.io/hpsc/> for more information, documents and examples.

This package provides estimation of simultaneous bootstrap and asymptotic confidence intervals for diversity indices, namely the Shannon and the Simpson index. Several pre--specified multiple comparison types are available to choose. Further user--defined contrast matrices are applicable. In addition, simboot estimates adjusted as well as unadjusted p--values for two of the three proposed bootstrap methods. Further simboot allows for comparing biological diversities of two or more groups while simultaneously testing a user-defined selection of Hill numbers of orders q, which are considered as appropriate and useful indices for measuring diversity.

This package provides a collection of tools for analyzing significance of assets, funds, and trading strategies, based on the Sharpe ratio and overfit of the same. Provides density, distribution, quantile and random generation of the Sharpe ratio distribution based on normal returns, as well as the optimal Sharpe ratio over multiple assets. Computes confidence intervals on the Sharpe and provides a test of equality of Sharpe ratios based on the Delta method. The statistical foundations of the Sharpe can be found in the author's Short Sharpe Course <doi:10.2139/ssrn.3036276>.

MEM, Marker Enrichment Modeling, automatically generates and displays quantitative labels for cell populations that have been identified from single-cell data. The input for MEM is a dataset that has pre-clustered or pre-gated populations with cells in rows and features in columns. Labels convey a list of measured features and the features levels of relative enrichment on each population. MEM can be applied to a wide variety of data types and can compare between MEM labels from flow cytometry, mass cytometry, single cell RNA-seq, and spectral flow cytometry using RMSD.

Functionality for working with virtual machines (VMs) in Microsoft's Azure cloud: <https://azure.microsoft.com/en-us/services/virtual-machines/>. Includes facilities to deploy, startup, shutdown, and cleanly delete VMs and VM clusters. Deployment configurations can be highly customised, and can make use of existing resources as well as creating new ones. A selection of predefined configurations is provided to allow easy deployment of commonly used Linux and Windows images, including Data Science Virtual Machines. With a running VM, execute scripts and install optional extensions. Part of the AzureR family of packages.

Maximum likelihood estimation, random values generation, density computation and other functions for the bivariate Poisson distribution. References include: Kawamura K. (1984). "Direct calculation of maximum likelihood estimator for the bivariate Poisson distribution". Kodai Mathematical Journal, 7(2): 211--221. <doi:10.2996/kmj/1138036908>. Kocherlakota S. and Kocherlakota K. (1992). "Bivariate discrete distributions". CRC Press. <doi:10.1201/9781315138480>. Karlis D. and Ntzoufras I. (2003). "Analysis of sports data by using bivariate Poisson models". Journal of the Royal Statistical Society: Series D (The Statistician), 52(3): 381--393. <doi:10.1111/1467-9884.00366>.

This package provides functions for training an optimal decision tree classifier, making predictions and generating latex code for plotting. Works for two-class and multi-class classification problems. The algorithm seeks the optimal Boolean rule consisting of multiple variables to split a node, resulting in shorter trees. Use bsnsing() to build a tree, predict() to make predictions and plot() to plot the tree into latex and PDF. See Yanchao Liu (2022) <arXiv:2205.15263> for technical details. Source code and more data sets are at <https://github.com/profyliu/bsnsing/>.

This package provides a practical tool for estimating the burden of common communicable diseases in settlements of displaced populations. An online version of the tool can be found at <http://who-refugee-bod.ecdf.ed.ac.uk/shiny/app/>. Estimates of burden of disease aim to synthesize data about cause-specific morbidity and mortality through a systematic approach that enables evidence-based decisions and comparisons across settings. The focus of this tool is on four acute communicable diseases and syndromes, including Acute respiratory infections, Acute diarrheal diseases, Acute jaundice syndrome and Acute febrile illnesses.

We propose to determine the correction of the significance level after multiple coding of an explanatory variable in Generalized Linear Model. The different methods of correction of the p-value are the Single step Bonferroni procedure, and resampling based methods developed by P.H.Westfall in 1993. Resampling methods are based on the permutation and the parametric bootstrap procedure. If some continuous, and dichotomous transformations are performed this package offers an exact correction of the p-value developed by B.Liquet & D.Commenges in 2005. The naive method with no correction is also available.

Demonstration code showing how (univariate) kernel density estimates are computed, at least conceptually, and allowing users to experiment with different kernels, should they so wish. The method used follows directly the definition, but gains efficiency by replacing the observations by frequencies in a very fine grid covering the sample range. A canonical reference is B. W. Silverman, (1998) <doi: 10.1201/9781315140919>. NOTE: the density function in the stats package uses a more sophisticated method based on the fast Fourier transform and that function should be used if computational efficiency is a prime consideration.

Read and write PNG images with arrays, rasters, native rasters, numeric arrays, integer arrays, raw vectors and indexed values. This PNG encoder exposes configurable internal options enabling the user to select a speed-size tradeoff. For example, disabling compression can speed up writing PNG by a factor of 50. Multiple image formats are supported including raster, native rasters, and integer and numeric arrays at color depths of 1, 2, 3 or 4. 16-bit images are also supported. This implementation uses the libspng C library which is available from <https://github.com/randy408/libspng/>.

This presents a comprehensive set of tools for the analysis and visualization of drug formulation data. It includes functions for statistical analysis, regression modeling, hypothesis testing, and comparative analysis to assess the impact of formulation parameters on drug release and other critical attributes. Additionally, the package offers a variety of data visualization functions, such as scatterplots, histograms, and boxplots, to facilitate the interpretation of formulation data. With its focus on usability and efficiency, this package aims to streamline the drug formulation process and aid researchers in making informed decisions during formulation design and optimization.