Maximum likelihood estimation, random values generation, density computation and other functions for the bivariate Poisson distribution. References include: Kawamura K. (1984). "Direct calculation of maximum likelihood estimator for the bivariate Poisson distribution". Kodai Mathematical Journal, 7(2): 211--221. <doi:10.2996/kmj/1138036908>. Kocherlakota S. and Kocherlakota K. (1992). "Bivariate discrete distributions". CRC Press. <doi:10.1201/9781315138480>. Karlis D. and Ntzoufras I. (2003). "Analysis of sports data by using bivariate Poisson models". Journal of the Royal Statistical Society: Series D (The Statistician), 52(3): 381--393. <doi:10.1111/1467-9884.00366>.

We propose to determine the correction of the significance level after multiple coding of an explanatory variable in Generalized Linear Model. The different methods of correction of the p-value are the Single step Bonferroni procedure, and resampling based methods developed by P.H.Westfall in 1993. Resampling methods are based on the permutation and the parametric bootstrap procedure. If some continuous, and dichotomous transformations are performed this package offers an exact correction of the p-value developed by B.Liquet & D.Commenges in 2005. The naive method with no correction is also available.

Demonstration code showing how (univariate) kernel density estimates are computed, at least conceptually, and allowing users to experiment with different kernels, should they so wish. The method used follows directly the definition, but gains efficiency by replacing the observations by frequencies in a very fine grid covering the sample range. A canonical reference is B. W. Silverman, (1998) <doi: 10.1201/9781315140919>. NOTE: the density function in the stats package uses a more sophisticated method based on the fast Fourier transform and that function should be used if computational efficiency is a prime consideration.

Read and write PNG images with arrays, rasters, native rasters, numeric arrays, integer arrays, raw vectors and indexed values. This PNG encoder exposes configurable internal options enabling the user to select a speed-size tradeoff. For example, disabling compression can speed up writing PNG by a factor of 50. Multiple image formats are supported including raster, native rasters, and integer and numeric arrays at color depths of 1, 2, 3 or 4. 16-bit images are also supported. This implementation uses the libspng C library which is available from <https://github.com/randy408/libspng/>.

This presents a comprehensive set of tools for the analysis and visualization of drug formulation data. It includes functions for statistical analysis, regression modeling, hypothesis testing, and comparative analysis to assess the impact of formulation parameters on drug release and other critical attributes. Additionally, the package offers a variety of data visualization functions, such as scatterplots, histograms, and boxplots, to facilitate the interpretation of formulation data. With its focus on usability and efficiency, this package aims to streamline the drug formulation process and aid researchers in making informed decisions during formulation design and optimization.

Readable, complete and pretty graphs for correspondence analysis made with FactoMineR'. They can be rendered as interactive HTML plots, showing useful informations at mouse hover. The interest is not mainly visual but statistical: it helps the reader to keep in mind the data contained in the cross-table or Burt table while reading the correspondence analysis, thus preventing over-interpretation. Most graphs are made with ggplot2', which means that you can use the + syntax to manually add as many graphical pieces you want, or change theme elements. 3D graphs are made with plotly'.

This package provides a set of tools to i) identify geographic areas with significant change over time in drug utilization, and ii) characterize common change over time patterns among the time series for multiple geographic areas. For reference, see below: 1. Song, J., Carey, M., Zhu, H., Miao, H., Ram´ırez, J. C., & Wu, H. (2018) <doi:10.1504/IJCBDD.2018.10011910> 2. Wu, S., Wu, H. (2013) <doi:10.1186/1471-2105-14-6> 3. Carey, M., Wu, S., Gan, G. & Wu, H. (2016) <doi:10.1016/j.idm.2016.07.001>.

Four datasets are provided here from the Intendo game Super Jetroid'. It is data from the 2015 year of operation and it comprises a revenue table ('all_revenue'), a daily users table ('users_daily'), a user summary table ('user_summary'), and a table with data on all user sessions ('all_sessions'). These core datasets come in different sizes, and, each of them has a variant that was intentionally made faulty (totally riddled with errors and inconsistencies). This suite of tables is useful for testing with packages that focus on data validation and data documentation.

Mass measurement corrections and uncertainties using calibration data, as recommended by EURAMET's guideline No. 18 (2015) ISBN:978-3-942992-40-4 . The package provides classes, functions, and methods for storing information contained in calibration certificates and converting balance readings to both conventional mass and real mass. For the latter, the Magnitude of the Air Buoyancy Correction factor employs models (such as the CIMP-2007 formula revised by Picard, Davis, Gläser, and Fujii (2008) <doi:10.1088/0026-1394/45/2/004>) to estimate the local air density using measured environmental conditions.

An implementation of the alternating expectation conditional maximization (AECM) algorithm for matrix-variate variance gamma (MVVG) and normal-inverse Gaussian (MVNIG) linear models. These models are designed for settings of multivariate analysis with clustered non-uniform observations and correlated responses. The package includes fitting and prediction functions for both models, and an example dataset from a periodontal on Gullah-speaking African Americans, with responses in gaad_res, and covariates in gaad_cov. For more details on the matrix-variate distributions used, see Gallaugher & McNicholas (2019) <doi:10.1016/j.spl.2018.08.012>.

This package provides a unified and user-friendly framework for applying the principal sufficient dimension reduction methods for both linear and nonlinear cases. The package has an extendable power by varying loss functions for the support vector machine, even for an user-defined arbitrary function, unless those are convex and differentiable everywhere over the support (Li et al. (2011) <doi:10.1214/11-AOS932>). Also, it provides a real-time sufficient dimension reduction update procedure using the principal least squares support vector machine (Artemiou et al. (2021) <doi:10.1016/j.patcog.2020.107768>).

This package provides a collection of (wrapper) functions the creator found useful for quickly placing data summaries and formatted regression results into .Rnw or .Rmd files. Functions for generating commonly used graphics, such as receiver operating curves or Bland-Altman plots, are also provided by qwraps2'. qwraps2 is a updated version of a package qwraps'. The original version qwraps was never submitted to CRAN but can be found at <https://github.com/dewittpe/qwraps/>. The implementation and limited scope of the functions within qwraps2 <https://github.com/dewittpe/qwraps2/> is fundamentally different from qwraps'.

This package provides functions and methods for estimating phenological dates (green up, start of a season, maturity, senescence, end of a season and dormancy) from (nearly) periodic Earth Observation time series. These dates are critical points of some derivatives of an idealized curve which, in turn, is obtained through a functional principal component analysis-based regression model. Some of the methods implemented here are based on T. Krivobokova, P. Serra and F. Rosales (2022) <https://www.sciencedirect.com/science/article/pii/S0167947322000998>. Methods for handling and plotting Earth observation time series are also provided.

This package ADAMgui is a graphical user interface (GUI) for the ADAM package. The ADAMgui package provides two shiny-based applications that allows the user to study the output of the ADAM package files through different plots. It's possible, for example, to choose a specific group of functionally associated genes (GFAG) and observe the gene expression behavior with the plots created with the GFAGtargetUi function. Features such as differential expression and fold change can be easily seen with aid of the plots made with the GFAGpathUi function.

Mail is an internet library for Ruby that is designed to handle email generation, parsing and sending. The purpose of this library is to provide a single point of access to handle all email functions, including sending and receiving emails. All network type actions are done through proxy methods to Net::SMTP, Net::POP3 etc.

Mail has been designed with a very simple object oriented system that really opens up the email messages you are parsing, if you know what you are doing, you can fiddle with every last bit of your email directly.

Many two-colour hybridizations suffer from a dye bias that is both gene-specific and slide-specific. The former depends on the content of the nucleotide used for labeling; the latter depends on the labeling percentage. The slide-dependency was hitherto not recognized, and made addressing the artefact impossible. Given a reasonable number of dye-swapped pairs of hybridizations, or of same vs. same hybridizations, both the gene- and slide-biases can be estimated and corrected using the GASSCO method (Margaritis et al., Mol. Sys. Biol. 5:266 (2009), doi:10.1038/msb.2009.21).

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.

Classifies the type of cancer using routinely collected data commonly found in cancer registries from pathology reports. The package implements the International Classification of Diseases for Oncology, 3rd Edition site (topography), histology (morphology), and behaviour codes of neoplasms to classify cancer type <https://www.who.int/standards/classifications/other-classifications/international-classification-of-diseases-for-oncology>. Classification in children utilize the International Classification of Childhood Cancer by Steliarova-Foucher et al. (2005) <doi:10.1002/cncr.20910>. Adolescent and young adult cancer classification is based on Barr et al. (2020) <doi:10.1002/cncr.33041>.

Collection of functions to evaluate uncertainty of results from water quality analysis using the Weighted Regressions on Time Discharge and Season (WRTDS) method. This package is an add-on to the EGRET package that performs the WRTDS analysis. The WRTDS modeling method was initially introduced and discussed in Hirsch et al. (2010) <doi:10.1111/j.1752-1688.2010.00482.x>, and expanded in Hirsch and De Cicco (2015) <doi:10.3133/tm4A10>. The paper describing the uncertainty and confidence interval calculations is Hirsch et al. (2015) <doi:10.1016/j.envsoft.2015.07.017>.

Estimation of production functions by the Olley-Pakes, Levinsohn-Petrin and Wooldridge methodologies. The package aims to reproduce the results obtained with the Stata's user written opreg <http://www.stata-journal.com/article.html?article=st0145> and levpet <http://www.stata-journal.com/article.html?article=st0060> commands. The first was originally proposed by Olley, G.S. and Pakes, A. (1996) <doi:10.2307/2171831>. The second by Levinsohn, J. and Petrin, A. (2003) <doi:10.1111/1467-937X.00246>. And the third by Wooldridge (2009) <doi:10.1016/j.econlet.2009.04.026>.

Accurate and computationally efficient p-value calculation methods for a general family of Fisher type statistics (GFisher). The GFisher covers Fisher's combination, Good's statistic, Lancaster's statistic, weighted Z-score combination, etc. It allows a flexible weighting scheme, as well as an omnibus procedure that automatically adapts proper weights and degrees of freedom to a given data. The new p-value calculation methods are based on novel ideas of moment-ratio matching and joint-distribution approximation. The technical details can be found in Hong Zhang and Zheyang Wu (2020) <arXiv:2003.01286>.

This package provides a framework for analytically computing the asymptotic confidence intervals and maximum-likelihood estimates of a class of continuous-time Gaussian branching processes defined by Mitov V, Bartoszek K, Asimomitis G, Stadler T (2019) <doi:10.1016/j.tpb.2019.11.005>. The class of model includes the widely used Ornstein-Uhlenbeck and Brownian motion branching processes. The framework is designed to be flexible enough so that the users can easily specify their own sub-models, or re-parameterizations, and obtain the maximum-likelihood estimates and confidence intervals of their own custom models.

Implementing Hierarchical Bayesian Small Area Estimation models using the brms package as the computational backend. The modeling framework follows the methodological foundations described in area-level models. This package is designed to facilitate a principled Bayesian workflow, enabling users to conduct prior predictive checks, model fitting, posterior predictive checks, model comparison, and sensitivity analysis in a coherent and reproducible manner. It supports flexible model specifications via brms and promotes transparency in model development, aligned with the recommendations of modern Bayesian data analysis practices, implementing methods described in Rao and Molina (2015) <doi:10.1002/9781118735855>.

Presentation of distributions such as: two-piece power normal (TPPN), plasticizing component (PC), DS normal (DSN), expnormal (EN), Sulewski plasticizing component (SPC), easily changeable kurtosis (ECK) distributions. Density, distribution function, quantile function and random generation are presented. For details on this method see: Sulewski (2019) <doi:10.1080/03610926.2019.1674871>, Sulewski (2021) <doi:10.1080/03610926.2020.1837881>, Sulewski (2021) <doi:10.1134/S1995080221120337>, Sulewski (2022) <"New members of the Johnson family of probability dis-tributions: properties and application">, Sulewski, Volodin (2022) <doi:10.1134/S1995080222110270>, Sulewski (2023) <doi:10.17713/ajs.v52i3.1434>.