This package provides functions and command-line user interface to generate allocation sequence by response-adaptive randomization for clinical trials. The package currently supports two families of frequentist response-adaptive randomization procedures, Doubly Adaptive Biased Coin Design ('DBCD') and Sequential Estimation-adjusted Urn Model ('SEU'), for binary and normal endpoints. One-sided proportion (or mean) difference and Chi-square (or ANOVA') hypothesis testing methods are also available in the package to facilitate the inference for treatment effect. Additionally, the package provides comprehensive and efficient tools to allow one to evaluate and compare the performance of randomization procedures and tests based on various criteria. For example, plots for relationship among assumed treatment effects, sample size, and power are provided. Five allocation functions for DBCD and six addition rule functions for SEU are implemented to target allocations such as Neyman', Rosenberger Rosenberger et al. (2001) <doi:10.1111/j.0006-341X.2001.00909.x> and Urn allocations.

Calculate confidence intervals for alpha and standardized alpha using asymptotic theory or the studentized bootstrap, with or without transformations. Supports the asymptotic distribution-free method of Maydeu-Olivares, et al. (2007) <doi:10.1037/1082-989X.12.2.157>, the pseudo-elliptical method of Yuan & Bentler (2002) <doi:10.1007/BF02294845>, and the normal method of van Zyl et al. (1999) <doi:10.1007/BF02296146>, for both coefficient alpha and standardized alpha.

It is an open source insurance claim simulation engine sponsored by the Casualty Actuarial Society. It generates individual insurance claims including open claims, reopened claims, incurred but not reported claims and future claims. It also includes claim data fitting functions to help set simulation assumptions. It is useful for claim level reserving analysis. Parodi (2013) <https://www.actuaries.org.uk/documents/triangle-free-reserving-non-traditional-framework-estimating-reserves-and-reserve-uncertainty>.

This package provides methods of computerized adaptive testing for survey researchers. See Montgomery and Rossiter (2020) <doi:10.1093/jssam/smz027>. Includes functionality for data fit with the classic item response methods including the latent trait model, Birnbaum`s three parameter model, the graded response, and the generalized partial credit model. Additionally, includes several ability parameter estimation and item selection routines. During item selection, all calculations are done in compiled C++ code.

Unifying an inconsistently coded categorical variable between two different time points in accordance with a mapping table. The main rule is to replicate the observation if it could be assigned to a few categories. Then using frequencies or statistical methods to approximate the probabilities of being assigned to each of them. This procedure was invented and implemented in the paper by Nasinski, Majchrowska, and Broniatowska (2020) <doi:10.24425/cejeme.2020.134747>.

Bindings for additional classification models for use with the parsnip package. Models include flavors of discriminant analysis, such as linear (Fisher (1936) <doi:10.1111/j.1469-1809.1936.tb02137.x>), regularized (Friedman (1989) <doi:10.1080/01621459.1989.10478752>), and flexible (Hastie, Tibshirani, and Buja (1994) <doi:10.1080/01621459.1994.10476866>), as well as naive Bayes classifiers (Hand and Yu (2007) <doi:10.1111/j.1751-5823.2001.tb00465.x>).

Connect to Elasticsearch', a NoSQL database built on the Java Virtual Machine. Interacts with the Elasticsearch HTTP API (<https://www.elastic.co/elasticsearch/>), including functions for setting connection details to Elasticsearch instances, loading bulk data, searching for documents with both HTTP query variables and JSON based body requests. In addition, elastic provides functions for interacting with API's for indices', documents, nodes, clusters, an interface to the cat API, and more.

Figures, data sets and examples from the book "A practical guide to ecological modelling - using R as a simulation platform" by Karline Soetaert and Peter MJ Herman (2009). Springer. All figures from chapter x can be generated by "demo(chapx)", where x = 1 to 11. The R-scripts of the model examples discussed in the book are in subdirectory "examples", ordered per chapter. Solutions to model projects are in the same subdirectories.

Creation of imprecise classification trees. They rely on probability estimation within each node by means of either the imprecise Dirichlet model or the nonparametric predictive inference approach. The splitting variable is selected by the strategy presented in Fink and Crossman (2013) <http://www.sipta.org/isipta13/index.php?id=paper&paper=014.html>, but also the original imprecise information gain of Abellan and Moral (2003) <doi:10.1002/int.10143> is covered.

This package implements transfer learning methods for low-rank matrix estimation. These methods leverage similarity in the latent row and column spaces between the source and target populations to improve estimation in the target population. The methods include the LatEnt spAce-based tRaNsfer lEaRning (LEARNER) method and the direct projection LEARNER (D-LEARNER) method described by McGrath et al. (2024) <doi:10.48550/arXiv.2412.20605>.

This package provides functions for fitting a functional principal components logit regression model in four different situations: ordinary and filtered functional principal components of functional predictors, included in the model according to their variability explanation power, and according to their prediction ability by stepwise methods. The proposed methods were developed in Escabias et al (2004) <doi:10.1080/10485250310001624738> and Escabias et al (2005) <doi:10.1016/j.csda.2005.03.011>.

Fits multivariate (Brownian Motion, Early Burst, ACDC, Ornstein-Uhlenbeck and Shifts) models of continuous traits evolution on trees and time series. mvMORPH also proposes high-dimensional multivariate comparative tools (linear models using Generalized Least Squares and multivariate tests) based on penalized likelihood. See Clavel et al. (2015) <DOI:10.1111/2041-210X.12420>, Clavel et al. (2019) <DOI:10.1093/sysbio/syy045>, and Clavel & Morlon (2020) <DOI:10.1093/sysbio/syaa010>.

Computation of standardized interquartile range (IQR), Huber-type skipped mean (Hampel (1985), <doi:10.2307/1268758>), robust coefficient of variation (CV) (Arachchige et al. (2019), <arXiv:1907.01110>), robust signal to noise ratio (SNR), z-score, standardized mean difference (SMD), as well as functions that support graphical visualization such as boxplots based on quartiles (not hinges), negative logarithms and generalized logarithms for ggplot2 (Wickham (2016), ISBN:978-3-319-24277-4).

Measure productivity and efficiency using Data Envelopment Analysis (DEA). Available methods include DEA under different technology assumptions, bootstrapping of efficiency scores and calculation of the Malmquist productivity index. Analyses can be performed either in the console or with the provided shiny app. See Banker, R.; Charnes, A.; Cooper, W.W. (1984) <doi:10.1287/mnsc.30.9.1078>, Färe, R.; Grosskopf, S. (1996) <doi:10.1007/978-94-009-1816-0>.

This package provides a toolkit of tidy data manipulation verbs with data.table as the backend. Combining the merits of syntax elegance from dplyr and computing performance from data.table', tidyfst intends to provide users with state-of-the-art data manipulation tools with least pain. This package is an extension of data.table'. While enjoying a tidy syntax, it also wraps combinations of efficient functions to facilitate frequently-used data operations.

Fit species distribution models (SDMs) using the tidymodels framework, which provides a standardised interface to define models and process their outputs. tidysdm expands tidymodels by providing methods for spatial objects, models and metrics specific to SDMs, as well as a number of specialised functions to process occurrences for contemporary and palaeo datasets. The full functionalities of the package are described in Leonardi et al. (2023) <doi:10.1101/2023.07.24.550358>.

This package provides a variety of tools to allow the quantification of videos of the lymphatic vasculature taken under an operating microscope. Lymphatic vessels that have been injected with a variety of blue dyes can be tracked throughout the video to determine their width over time. Code is optimised for efficient processing of multiple large video files. Functions to calculate physiologically relevant parameters and generate graphs from these values are also included.

This is a package that includes pre-processing and quality control functions that can remove margin events, compensate and transform the data and that will use PeacoQCSignalStability for quality control. This last function will first detect peaks in each channel of the flowframe. It will remove anomalies based on the IsolationTree function and the MAD outlier detection method. This package can be used for both flow- and mass cytometry data.

PathNet uses topological information present in pathways and differential expression levels of genes (obtained from microarray experiment) to identify pathways that are 1) significantly enriched and 2) associated with each other in the context of differential expression. The algorithm is described in: PathNet: A tool for pathway analysis using topological information. Dutta B, Wallqvist A, and Reifman J. Source Code for Biology and Medicine 2012 Sep 24;7(1):10.

The NGS (Next-Generation Sequencing) reads from FFPE (Formalin-Fixed Paraffin-Embedded) samples contain numerous artifact chimeric reads (ACRS), which can lead to false positive structural variant calls. These ACRs are derived from the combination of two single-stranded DNA (ss-DNA) fragments with short reverse complementary regions (SRCRs). This package simulates these artifact chimeric reads as well as normal reads for FFPE samples on the whole genome / several chromosomes / large regions.

Like all gene expression data, single-cell data suffers from batch effects and other unwanted variations that makes accurate biological interpretations difficult. The scMerge method leverages factor analysis, stably expressed genes (SEGs) and (pseudo-) replicates to remove unwanted variations and merge multiple single-cell data. This package contains all the necessary functions in the scMerge pipeline, including the identification of SEGs, replication-identification methods, and merging of single-cell data.

This package provides the cumulative distribution function (CDF), quantile, and statistical power calculator for a collection of thresholding Fisher's p-value combination methods, including Fisher's p-value combination method, truncated product method and, in particular, soft-thresholding Fisher's p-value combination method which is proven to be optimal in some context of signal detection. The p-value calculator for the omnibus version of these tests are also included.

This package provides tools for defining recurrence rules and recurrence sets. Recurrence rules are a programmatic way to define a recurring event, like the first Monday of December. Multiple recurrence rules can be combined into larger recurrence sets. A full holiday and calendar interface is also provided that can generate holidays within a particular year, can detect if a date is a holiday, can respect holiday observance rules, and allows for custom holidays.

As heavy-tailed error distribution and outliers in the response variable widely exist, models which are robust to data contamination are highly demanded. Here, we develop a novel robust Bayesian variable selection method with elastic net penalty. In particular, the spike-and-slab priors have been incorporated to impose sparsity. An efficient Gibbs sampler has been developed to facilitate computation.The core modules of the package have been developed in C++ and R.