This package provides functions useful in the design and ANOVA of experiments. The content falls into the following groupings:
data,
factor manipulation functions,
design functions,
ANOVA functions,
matrix functions,
projector and canonical efficiency functions, and
miscellaneous functions.
There is a vignette called DesignNotes describing how to use the design functions for randomizing and assessing designs. The ANOVA functions facilitate the extraction of information when the Error function has been used in the call to aov.
Single-cell RNA-sequencing (scRNA-seq) is widely used to explore cellular variation. The analysis of scRNA-seq data often starts from clustering cells into subpopulations. This initial step has a high impact on downstream analyses, and hence it is important to be accurate. However, there have not been unsupervised metric designed for scRNA-seq to evaluate clustering performance. Hence, we propose clustering deviation index (CDI), an unsupervised metric based on the modeling of scRNA-seq UMI counts to evaluate clustering of cells.
The Well-Plate Maker (WPM) is a shiny application deployed as an R package. Functions for a command-line/script use are also available. The WPM allows users to generate well plate maps to carry out their experiments while improving the handling of batch effects. In particular, it helps controlling the "plate effect" thanks to its ability to randomize samples over multiple well plates. The algorithm for placing the samples is inspired by the backtracking algorithm: the samples are placed at random while respecting specific spatial constraints.
The desirable Dietary Pattern (DDP)/ PPH score measures the variety of food consumption. The (weighted) score is calculated based on the type of food. This package is intended to calculate the DDP/ PPH score that is faster than traditional method via a manual calculation by BKP (2017) <http://bkp.pertanian.go.id/storage/app/uploads/public/5bf/ca9/06b/5bfca906bc654274163456.pdf> and is simpler than the nutrition survey <http://www.nutrisurvey.de>. The database to create weights and baseline values is the Indonesia national survey in 2017.
Treatments of a one-way layout, being equivalent to a control, can be selected with this package. Bonferroni adjusted "two one-sided t-tests" (TOST) and related simultaneous confidence intervals are given for both differences or ratios of means of normally distributed data. For the case of equal variances and balanced sample sizes for the treatment groups, the single-step procedure of Bofinger and Bofinger (1995) <doi:10.1111/j.2517-6161.1995.tb02058.x> can be chosen. For non-normal data, the Wilcoxon test is applied.
Multiple testing procedures for heterogeneous and discrete tests as described in Döhler and Roquain (2020) <doi:10.1214/20-EJS1771>. The main algorithms of the paper are available as continuous, discrete and weighted versions. They take as input the results of a test procedure from package DiscreteTests', or a set of observed p-values and their discrete support under their nulls. A shortcut function to obtain such p-values and supports is also provided, along with wrappers allowing to apply discrete procedures directly to data.
This package provides quick and easy access to official spatial data from Germanyâ s Federal Agency for Cartography and Geodesy (BKG) <https://gdz.bkg.bund.de/>. Interfaces various web feature services (WFS) and download servers. Allows retrieval, caching and filtering with a wide range of open geodata products, including administrative or non-administrative boundaries, land cover, elevation models, geographic names, and points of interest covering Germany. Can be particularly useful for linking regional statistics to their spatial representations and streamlining workflows that involve spatial data of Germany.
Builds and runs c++ code for classes that encapsulate state space model, particle filtering algorithm pairs. Algorithms include the Bootstrap Filter from Gordon et al. (1993) <doi:10.1049/ip-f-2.1993.0015>, the generic SISR filter, the Auxiliary Particle Filter from Pitt et al (1999) <doi:10.2307/2670179>, and a variety of Rao-Blackwellized particle filters inspired by Andrieu et al. (2002) <doi:10.1111/1467-9868.00363>. For more details on the c++ library pf', see Brown (2020) <doi:10.21105/joss.02599>.
Developed to perform the estimation and inference for regression coefficient parameters in longitudinal marginal models using the method of quadratic inference functions. Like generalized estimating equations, this method is also a quasi-likelihood inference method. It has been showed that the method gives consistent estimators of the regression coefficients even if the correlation structure is misspecified, and it is more efficient than GEE when the correlation structure is misspecified. Based on Qu, A., Lindsay, B.G. and Li, B. (2000) <doi:10.1093/biomet/87.4.823>.
This package provides researchers with a simple set of diagnostic tools for monitoring the progress and reliability of raters conducting content coding tasks. Goehring (2024) <https://bengoehring.github.io/improving-content-analysis-tools-for-working-with-undergraduate-research-assistants.pdf> argues that supervisors---especially supervisors of small teams---should utilize computational tools to monitor reliability in real time. As such, this package provides easy-to-use functions for calculating inter-rater reliability statistics and measuring the reliability of one coder compared to the rest of the team.
This package provides methods for fast access to large ASCII files. Currently the following file formats are supported: comma separated format (CSV) and fixed width format. It is assumed that the files are too large to fit into memory, although the package can also be used to efficiently access files that do fit into memory. Methods are provided to access and process files blockwise. Furthermore, an opened file can be accessed as one would an ordinary data.frame. The LaF vignette gives an overview of the functionality provided.
PAA imports single color (protein) microarray data that has been saved in gpr file format - esp. ProtoArray data. After preprocessing (background correction, batch filtering, normalization) univariate feature preselection is performed (e.g., using the "minimum M statistic" approach - hereinafter referred to as "mMs"). Subsequently, a multivariate feature selection is conducted to discover biomarker candidates. Therefore, either a frequency-based backwards elimination aproach or ensemble feature selection can be used. PAA provides a complete toolbox of analysis tools including several different plots for results examination and evaluation.
This package provides a collection of tools to create, use and maintain modularized model code written in the modeling language GAMS (<https://www.gams.com/>). Out-of-the-box GAMS does not come with support for modularized model code. This package provides the tools necessary to convert a standard GAMS model to a modularized one by introducing a modularized code structure together with a naming convention which emulates local environments. In addition, this package provides tools to monitor the compliance of the model code with modular coding guidelines.
Generalized factor model is implemented for ultra-high dimensional data with mixed-type variables. Two algorithms, variational EM and alternate maximization, are designed to implement the generalized factor model, respectively. The factor matrix and loading matrix together with the number of factors can be well estimated. This model can be employed in social and behavioral sciences, economy and finance, and genomics, to extract interpretable nonlinear factors. More details can be referred to Wei Liu, Huazhen Lin, Shurong Zheng and Jin Liu. (2023) <doi:10.1080/01621459.2021.1999818>.
This package provides a high level interface for torch providing utilities to reduce the the amount of code needed for common tasks, abstract away torch details and make the same code work on both the CPU and GPU'. It's flexible enough to support expressing a large range of models. It's heavily inspired by fastai by Howard et al. (2020) <doi:10.48550/arXiv.2002.04688>, Keras by Chollet et al. (2015) and PyTorch Lightning by Falcon et al. (2019) <doi:10.5281/zenodo.3828935>.
This package provides a framework for organizing R projects with a standardized structure. Most analyses consist of three main components: code, results, and data, each with different requirements such as version control, sharing, and encryption. This package provides tools to set up and manage project directories, handle file paths consistently across operating systems, organize results using date-based structures, source code from specified directories, create and manage Quarto documents, and perform file operations safely. It ensures consistency across projects while accommodating different requirements for various types of content.
Bayesian Model Averaging for linear models with a wide choice of (customizable) priors. Built-in priors include coefficient priors (fixed, hyper-g and empirical priors), 5 kinds of model priors, moreover model sampling by enumeration or various MCMC approaches. Post-processing functions allow for inferring posterior inclusion and model probabilities, various moments, coefficient and predictive densities. Plotting functions available for posterior model size, MCMC convergence, predictive and coefficient densities, best models representation, BMA comparison. Also includes Bayesian normal-conjugate linear model with Zellner's g prior, and assorted methods.
Firstly, both functions of the univariate Poisson dispersion index (DI) for count data and the univariate exponential variation index (VI) for nonnegative continuous data are performed. Next, other functions of univariate indexes such the binomial dispersion index (DIb), the negative binomial dispersion index (DInb) and the inverse Gaussian variation index (VIiG) are given. Finally, we are computed some multivariate versions of these functions such that the generalized dispersion index (GDI) with its marginal one (MDI) and the generalized variation index (GVI) with its marginal one (MVI) too.
This package provides probability density functions and sampling algorithms for three key distributions from the General Unimodal Distribution (GUD) family: the Flexible Gumbel (FG) distribution, the Double Two-Piece (DTP) Student-t distribution, and the Two-Piece Scale (TPSC) Student-t distribution. Additionally, this package includes a function for Bayesian linear modal regression, leveraging these three distributions for model fitting. The details of the Bayesian modal regression model based on the GUD family can be found at Liu, Huang, and Bai (2024) <doi:10.1016/j.csda.2024.108012>.
Analysis of complex ANOVA models with any combination of orthogonal/nested and fixed/random factors, as described by Underwood (1997). There are two restrictions: (i) data must be balanced; (ii) fixed nested factors are not allowed. Homogeneity of variances is checked using Cochran's C test and a posteriori comparisons of means are done using Student-Newman-Keuls (SNK) procedure. For those terms with no denominator in the F-ratio calculation, pooled mean squares and quasi F-ratios are provided. Magnitute of effects are assessed by components of variation.
Metadata about populations and data about samples from the 1000 Genomes Project, including the 2,504 samples sequenced for the Phase 3 release and the expanded collection of 3,202 samples with 602 additional trios. The data is described in Auton et al. (2015) <doi:10.1038/nature15393> and Byrska-Bishop et al. (2022) <doi:10.1016/j.cell.2022.08.004>, and raw data is available at <http://ftp.1000genomes.ebi.ac.uk/vol1/ftp/>. See Turner (2022) <doi:10.48550/arXiv.2210.00539> for more details.
Computes Logistic Knowledge Tracing ('LKT') which is a general method for tracking human learning in an educational software system. Please see Pavlik, Eglington, and Harrel-Williams (2021) <https://ieeexplore.ieee.org/document/9616435>. LKT is a method to compute features of student data that are used as predictors of subsequent performance. LKT allows great flexibility in the choice of predictive components and features computed for these predictive components. The system is built on top of LiblineaR', which enables extremely fast solutions compared to base glm() in R.
Derives prediction rule ensembles (PREs). Largely follows the procedure for deriving PREs as described in Friedman & Popescu (2008; <DOI:10.1214/07-AOAS148>), with adjustments and improvements described in Fokkema (2020; <DOI:10.18637/jss.v092.i12>) and Fokkema & Strobl (2020; <DOI:10.1037/met0000256>). The main function pre() derives prediction rule ensembles consisting of rules and/or linear terms for continuous, binary, count, multinomial, survival and multivariate continuous responses. Function gpe() derives generalized prediction ensembles, consisting of rules, hinge and linear functions of the predictor variables.
Implementation of Stepwise Clustered Ensemble (SCE) and Stepwise Cluster Analysis (SCA) for multivariate data analysis. The package provides comprehensive tools for feature selection, model training, prediction, and evaluation in hydrological and environmental modeling applications. Key functionalities include recursive feature elimination (RFE), Wilks feature importance analysis, model validation through out-of-bag (OOB) validation, and ensemble prediction capabilities. The package supports both single and multivariate response variables, making it suitable for complex environmental modeling scenarios. For more details see Li et al. (2021) <doi:10.5194/hess-25-4947-2021>.