This package provides a collection of functions to test spatial autocorrelation between variables, including Moran I, Geary C and Getis G together with scatter plots, functions for mapping and identifying clusters and outliers, functions associated with the moments of the previous statistics that will allow testing whether there is bivariate spatial autocorrelation, and a function that allows identifying (visualizing neighbours) on the map, the neighbors of any region once the scheme of the spatial weights matrix has been established.

Time series analysis of network connectivity. Detects and visualizes change points between networks. Methods included in the package are discussed in depth in Baek, C., Gates, K. M., Leinwand, B., Pipiras, V. (2021) "Two sample tests for high-dimensional auto-covariances" <doi:10.1016/j.csda.2020.107067> and Baek, C., Gampe, M., Leinwand B., Lindquist K., Hopfinger J. and Gates K. (2023) â Detecting functional connectivity changes in fMRI dataâ <doi:10.1007/s11336-023-09908-7>.

This package provides functions to test for gene x gene interactions in a bi-parental population of inbred lines. The data are fitted with the mixed linear model described in Rio et al. (2022) <doi:10.1101/2022.12.18.520958>, that accounts for gene x gene interactions at both the fixed effect and variance levels. The package also provides graphical tools to display the gene x gene interaction trend at the mean level and the variance component analysis.

Large-scale gridded data stores are increasingly using the Zarr format. GeoZarr is defined in terms of a number of community conventions built on top of the Zarr specification. These conventions specify how Zarr metadata is to be interpreted to attach semantic meaning to the data in the Zarr array providing the metadata. This package implements a number of community conventions on top of the zarr package, enabling the R community to use geospatial data stored in Zarr.

This package provides a ggplot2 extension providing an integrative framework for composable visualization, enabling the creation of complex multi-plot layouts such as insets, circular arrangements, and multi-panel compositions. Built on the grammar of graphics, it offers tools to align, stack, and nest plots, simplifying the construction of richly annotated figures for high-dimensional data contextsâ such as genomics, transcriptomics, and microbiome studiesâ by making it easy to link related plots, overlay clustering results, or highlight shared patterns.

This package provides a minimal-dependency client for Large Language Model chat APIs. Supports OpenAI <https://openai.com/>, Anthropic Claude <https://claude.com/>, Moonshot Kimi <https://www.moonshot.ai/>, OpenAI Codex subscription endpoints, Ollama <https://ollama.com/>, and other OpenAI'-compatible endpoints. Includes an agent loop with tool use and a Model Context Protocol client <https://modelcontextprotocol.io/>. API design is derived from the ellmer package, reimplemented with only base R, curl', jsonlite', and tinyoauth'.

Estimating GARCH-MIDAS (MIxed-DAta-Sampling) models (Engle, Ghysels, Sohn, 2013, <doi:10.1162/REST_a_00300>) and related statistical inference, accompanying the paper "Two are better than one: Volatility forecasting using multiplicative component GARCH models" by Conrad and Kleen (2020, <doi:10.1002/jae.2742>). The GARCH-MIDAS model decomposes the conditional variance of (daily) stock returns into a short- and long-term component, where the latter may depend on an exogenous covariate sampled at a lower frequency.

Inference of a multi-states birth-death model from a phylogeny, comprising a number of states N, birth and death rates for each state and on which edges each state appears. Inference is done using a hybrid approach: states are progressively added in a greedy approach. For a fixed number of states N the best model is selected via maximum likelihood. Reference: J. Barido-Sottani, T. G. Vaughan and T. Stadler (2018) <doi:10.1098/rsif.2018.0512>.

R interface for the netstat command line utility used to retrieve and parse commonly used network statistics, including available and in-use transmission control protocol (TCP) ports. Primers offering technical background information on the netstat command line utility are available in the "Linux System Administrator's Manual" by Michael Kerrisk (2014) <https://man7.org/linux/man-pages/man8/netstat.8.html>, and on the Microsoft website (2017) <https://docs.microsoft.com/en-us/windows-server/administration/windows-commands/netstat>.

An R-package-version of an open online science-based personality test from <https://openpsychometrics.org/tests/IPIP-BFFM/>, providing a better-designed interface and a more detailed report. The core command launch_test() opens a personality test in your browser, and generates a report after you click "Submit". In this report, your results are compared with other people's, to show what these results mean. Other people's data is from <https://openpsychometrics.org/_rawdata/BIG5.zip>.

The Common Workflow Language <https://www.commonwl.org/> is an open standard for describing data analysis workflows. This package takes the raw Common Workflow Language workflows encoded in JSON or YAML and turns the workflow elements into tidy data frames or lists. A graph representation for the workflow can be constructed and visualized with the parsed workflow inputs, outputs, and steps. Users can embed the visualizations in their Shiny applications, and export them as HTML files or static images.

Simple trustworthy utility functions to use TauDEM (Terrain Analysis Using Digital Elevation Models <https://hydrology.usu.edu/taudem/taudem5/>) command-line interface. This package provides a guide to installation of TauDEM and its dependencies GDAL (Geopatial Data Abstraction Library) and MPI (Message Passing Interface) for different operating systems. Moreover, it checks that TauDEM and its dependencies are correctly installed and included to the PATH, and it provides wrapper commands for calling TauDEM methods from R.

This package provides a testing method for inferring microbial networks. It differs from existing microbial network analyses in that it provides calibrated results by controlling the false discovery rate. The method accounts for the complex features of taxa count data. It also accommodates both independent and clustered samples, offers separate linear and nonlinear tests for each pair of taxa, and includes an omnibus test that bypasses the need to specify the type of relationship for each pair of taxa.

The shiny application Wallace is a modular platform for reproducible modeling of species niches and distributions. Wallace guides users through a complete analysis, from the acquisition of species occurrence and environmental data to visualizing model predictions on an interactive map, thus bundling complex workflows into a single, streamlined interface. An extensive vignette, which guides users through most package functionality can be found on the package's GitHub Pages website: <https://wallaceecomod.github.io/wallace/articles/tutorial-v2.html>.

Speech-to-text transcription using a native R torch implementation of OpenAI Whisper model <https://github.com/openai/whisper>. Supports multiple model sizes from tiny (39M parameters) to large-v3 (1.5B parameters) with integrated download from HuggingFace <https://huggingface.co/> via the hfhub package. Provides automatic speech recognition with optional language detection and translation to English. Audio preprocessing, mel spectrogram computation, and transformer-based encoder-decoder inference are all implemented in R using the torch package.

This package provides quantitative tools for assessing zoonotic disease risk across animal, human, environmental, and transmission interfaces. The package supports exposure and transmission risk estimation, spillover risk assessment, risk scoring, cross-species comparison, transmission-network analysis, Monte Carlo uncertainty simulation, and sensitivity analysis. The One Health framework underlying these assessments is described by World Health Organization, Food and Agriculture Organization of the United Nations, United Nations Environment Programme, and World Organisation for Animal Health (2022) <doi:10.4060/cc2289en>.

C++ classes to embed R in C++ (and C) applications A C++ class providing the R interpreter is offered by this package making it easier to have "R inside" your C++ application. As R itself is embedded into your application, a shared library build of R is required. This works on Linux, OS X and even on Windows provided you use the same tools used to build R itself. Numerous examples are provided in the nine subdirectories of the examples/ directory of the installed package: standard, mpi (for parallel computing), qt (showing how to embed RInside inside a Qt GUI application), wt (showing how to build a "web-application" using the Wt toolkit), armadillo (for RInside use with RcppArmadillo'), eigen (for RInside use with RcppEigen'), and c_interface for a basic C interface and Ruby illustration. The examples use GNUmakefile(s) with GNU extensions, so a GNU make is required (and will use the GNUmakefile automatically). Doxygen'-generated documentation of the C++ classes is available at the RInside website as well.

Estimates the pooled (unadjusted) Receiver Operating Characteristic (ROC) curve, the covariate-adjusted ROC (AROC) curve, and the covariate-specific/conditional ROC (cROC) curve by different methods, both Bayesian and frequentist. Also, it provides functions to obtain ROC-based optimal cutpoints utilizing several criteria. Based on Erkanli, A. et al. (2006) <doi:10.1002/sim.2496>; Faraggi, D. (2003) <doi:10.1111/1467-9884.00350>; Gu, J. et al. (2008) <doi:10.1002/sim.3366>; Inacio de Carvalho, V. et al. (2013) <doi:10.1214/13-BA825>; Inacio de Carvalho, V., and Rodriguez-Alvarez, M.X. (2022) <doi:10.1214/21-STS839>; Janes, H., and Pepe, M.S. (2009) <doi:10.1093/biomet/asp002>; Pepe, M.S. (1998) <http://www.jstor.org/stable/2534001?seq=1>; Rodriguez-Alvarez, M.X. et al. (2011a) <doi:10.1016/j.csda.2010.07.018>; Rodriguez-Alvarez, M.X. et al. (2011a) <doi:10.1007/s11222-010-9184-1>. Please see Rodriguez-Alvarez, M.X. and Inacio, V. (2021) <doi:10.32614/RJ-2021-066> for more details.

MetCirc comprises a workflow to interactively explore high-resolution MS/MS metabolomics data. MetCirc uses the Spectra object infrastructure defined in the package Spectra that stores MS/MS spectra. MetCirc offers functionality to calculate similarity between precursors based on the normalised dot product, neutral losses or user-defined functions and visualise similarities in a circular layout. Within the interactive framework the user can annotate MS/MS features based on their similarity to (known) related MS/MS features.

Scale4C is an R/Bioconductor package for scale-space transformation and visualization of 4C-seq data. The scale-space transformation is a multi-scale visualization technique to transform a 2D signal (e.g. 4C-seq reads on a genomic interval of choice) into a tesselation in the scale space (2D, genomic position x scale factor) by applying different smoothing kernels (Gauss, with increasing sigma). This transformation allows for explorative analysis and comparisons of the data's structure with other samples.

Enable translation of a tiny subset of R to C++. The user has to define a R function which gets translated. For a full list of possible functions check the documentation. After translation an R function is returned which is a shallow wrapper around the C++ code. Alternatively an external pointer to the C++ function is returned to the user. The intention of the package is to generate fast functions which can be used as ode-system or during optimization.

Bayesian quantile regression using the asymmetric Laplace distribution, both continuous as well as binary dependent variables are supported. The package consists of implementations of the methods of Yu & Moyeed (2001) <doi:10.1016/S0167-7152(01)00124-9>, Benoit & Van den Poel (2012) <doi:10.1002/jae.1216> and Al-Hamzawi, Yu & Benoit (2012) <doi:10.1177/1471082X1101200304>. To speed up the calculations, the Markov Chain Monte Carlo core of all algorithms is programmed in Fortran and called from R.

This package provides methods for difference-in-differences with a continuous treatment and staggered treatment adoption. Includes estimation of treatment effects and causal responses as a function of the dose, event studies indexed by length of exposure to the treatment, and aggregation into overall average effects. Uniform inference procedures are included, along with both parametric and nonparametric models for treatment effects. The methods are based on Callaway, Goodman-Bacon, and Sant'Anna (2025) <doi:10.48550/arXiv.2107.02637>.

Arbitrary-precision vectors with an exact decimal representation, avoiding the rounding surprises of binary floating point. Built on the mpdecimal C library, arithmetic is governed by an explicit decimal context controlling precision, rounding, and signaling, and vectors integrate with vctrs for use in data frames, tibble objects, summaries, and common numeric workflows. Missing values, signed zeros, infinities, and not-a-number values are supported throughout. The arithmetic model follows Cowlishaw (2009) "General Decimal Arithmetic" <https://speleotrove.com/decimal/decarith.html>.