This package provides functions for range estimation in birds based on Pennycuick (2008) and Pennycuick (1975), Flight program which compliments Pennycuick (2008) requires manual entry of birds which can be tedious when there are hundreds of birds to estimate. Implemented are two ODE methods discussed in Pennycuick (1975) and time-marching computation methods as in Pennycuick (1998) and Pennycuick (2008). See Pennycuick (1975, ISBN:978-0-12-249405-5), Pennycuick (1998) <doi:10.1006/jtbi.1997.0572>, and Pennycuick (2008, ISBN:9780080557816).
Variance-aware Michaelis-Menten estimation, model screening, grouped enzyme-kinetic analyses, and clustered repeated-measurement workflows. The package implements profile-score estimators under working variance functions, together with a lightweight cluster-aware working-covariance extension, Wald and bootstrap confidence intervals, prediction utilities, and simulation helpers. Related methodology is discussed by Kim and Ma (2012) <doi:10.1007/s10463-011-0332-y>, Kim (2023) <doi:10.1002/sta4.606>, and Ma and Genton (2010) <doi:10.1111/j.1467-9868.2010.00741.x>.
Comprehensive instrumental variables and GMM estimation with automatic diagnostics, inspired by the Stata command ivreg2 of Baum, Schaffer, and Stillman (2003) <doi:10.1177/1536867X0300300101> and Baum, Schaffer, and Stillman (2007) <doi:10.1177/1536867X0800700402>. Supports 2SLS, LIML, Fuller, k-class, two-step efficient GMM, and continuously-updated (CUE) estimators. Provides classical, robust, cluster-robust, HAC, and Driscoll-Kraay standard errors. Reports weak identification, underidentification, overidentification, and endogeneity tests at estimation time. All outputs are verified against Stata within tight numerical tolerances.
This package provides convenient access to the German modification of the International Classification of Diagnoses, 10th revision (ICD-10-GM). It provides functionality to aid in the identification, specification and historisation of ICD-10 codes. Its intended use is the analysis of routinely collected data in the context of epidemiology, medical research and health services research. The underlying metadata are released by the German Institute for Medical Documentation and Information <https://www.dimdi.de>, and are redistributed in accordance with their license.
This package implements k-means like blockmodeling of one-mode and linked networks as presented in Žiberna (2020) <doi:10.1016/j.socnet.2019.10.006>. The development of this package is financially supported by the Slovenian Research Agency (<https://www.arrs.si/>) within the research programs P5-0168 and the research projects J7-8279 (Blockmodeling multilevel and temporal networks) and J5-2557 (Comparison and evaluation of different approaches to blockmodeling dynamic networks by simulations with application to Slovenian co-authorship networks).
This package provides a joint latent class model where a hierarchical structure exists, with an interaction between female and male partners of a couple. A Bayesian perspective to inference and Markov chain Monte Carlo algorithms to obtain posterior estimates of model parameters. The reference paper is: Beom Seuk Hwang, Zhen Chen, Germaine M.Buck Louis, Paul S. Albert, (2018) "A Bayesian multi-dimensional couple-based latent risk model with an application to infertility". Biometrics, 75, 315-325. <doi:10.1111/biom.12972>.
User-friendly and generalized tools for the calculation of luck -- moments of variation in metrics like lifespan and lifetime reproductive output. We provide tools for calculating those moments and also performing decompositions into contributions from, for example, individual traits, environmental impacts, and luck (also called individual stochasticity). The functions included here are based on Snyder and Ellner (2024) <doi:10.1086/730557>, Cochran and Ellner (1992) <https://www.jstor.org/stable/2937115>, and Hernandez et al. (2024) <doi:10.1111/ele.14390>.
This package creates and runs Bayesian mixing models to analyze biological tracer data (i.e. stable isotopes, fatty acids), which estimate the proportions of source (prey) contributions to a mixture (consumer). MixSIAR is not one model, but a framework that allows a user to create a mixing model based on their data structure and research questions, via options for fixed/ random effects, source data types, priors, and error terms. MixSIAR incorporates several years of advances since MixSIR and SIAR'.
This package provides tools for the stages of a single-case (N-of-1) experimental study that come before analysis: generating randomization schedules that can be preregistered and reproduced exactly, under run-length constraints, exporting them for mobile data collection, validating incoming ecological momentary assessment (EMA) records, and monitoring compliance. Designed around the workflow of a 70-day randomized N-of-1 study collected with stock iOS tools at 92.9% compliance; the package ships with that study's complete dataset.
This package performs robust cluster analysis allowing for outliers and noise that cannot be fitted by any cluster. The data are modelled by a mixture of Gaussian distributions and a noise component, which is an improper uniform distribution covering the whole Euclidean space. Parameters are estimated by (pseudo) maximum likelihood. This is fitted by a EM-type algorithm. See Coretto and Hennig (2016) <doi:10.1080/01621459.2015.1100996>, and Coretto and Hennig (2017) <https://jmlr.org/papers/v18/16-382.html>.
Estimating causal effects in the presence of post-treatment confounding using principal stratification. PStrata allows for customized monotonicity assumptions and exclusion restriction assumptions, with automatic full Bayesian inference supported by Stan'. The main workflow is PStrataModel() to specify the model, fit() to run MCMC sampling, estimate() to extract potential outcomes, and contrast() to compute causal effects. Visualization tools are provided for diagnosis and interpretation. See Liu and Li (2023) <doi:10.48550/arXiv.2304.02740> for details.
Numerical integration of continuously differentiable functions f(x,y) over simple closed polygonal domains. The following cubature methods are implemented: product Gauss cubature (Sommariva and Vianello, 2007, <doi:10.1007/s10543-007-0131-2>), the simple two-dimensional midpoint rule (wrapping spatstat.geom functions), and adaptive cubature for radially symmetric functions via line integrate() along the polygon boundary (Meyer and Held, 2014, <doi:10.1214/14-AOAS743>, Supplement B). For simple integration along the axes, the cubature package is more appropriate.
Aims to quantify time intensity data by using sigmoidal and double sigmoidal curves. It fits straight lines, sigmoidal, and double sigmoidal curves on to time vs intensity data. Then all the fits are used to make decision on which model best describes the data. This method was first developed in the context of single-cell viral growth analysis (for details, see Caglar et al. (2018) <doi:10.7717/peerj.4251>), and the package name stands for "SIngle CEll Growth Analysis in R".
This package provides functions to model and forecast crop yields using a spatial temporal conditional copula approach. The package incorporates extreme weather covariates and Bayesian Structural Time Series models to analyze crop yield dependencies across multiple regions. Includes tools for fitting, simulating, and visualizing results. This method build upon established R packages, including Hofert et al'. (2025) <doi:10.32614/CRAN.package.copula>, Scott (2024) <doi:10.32614/CRAN.package.bsts>, and Stephenson et al'. (2024) <doi:10.32614/CRAN.package.evd>.
This package provides tools to detect and correct measurement-unit errors in multivariate numeric data using model-based clustering. Gaussian mixture models with user-defined translation vectors identify clusters of records that differ in scale or unit. Core functionality includes cluster assignment via the EM algorithm, error correction based on posterior probabilities and pairwise scatterplot visualizations. For more details see Di Zio, Guarnera and Luzi (2005) <https://www150.statcan.gc.ca/n1/en/pub/12-001-x/2005001/article/8087-eng.pdf>.
The Seqinfo class stores the names, lengths, circularity flags, and genomes for a particular collection of sequences. These sequences are typically the chromosomes and/or scaffolds of a specific genome assembly of a given organism. Seqinfo objects are rarely used as standalone objects. Instead, they are used as part of higher-level objects to represent their seqinfo() component. Examples of such higher-level objects are GRanges, RangedSummarizedExperiment, VCF, GAlignments, etc… defined in other Bioconductor infrastructure packages.
When testing multiple hypotheses simultaneously, this package provides functionality to calculate a lower bound for the number of correct rejections (as a function of the number of rejected hypotheses), which holds simultaneously -with high probability- for all possible number of rejections. As a special case, a lower bound for the total number of false null hypotheses can be inferred. Dependent test statistics can be handled for multiple tests of associations. For independent test statistics, it is sufficient to provide a list of p-values.
This package provides userspace components for the InfiniBand subsystem of the Linux kernel. Specifically it contains userspace libraries for the following device nodes:
/dev/infiniband/uverbsX(libibverbs)/dev/infiniband/rdma_cm(librdmacm)/dev/infiniband/umadX(libibumad)
The following service daemons are also provided:
srp_daemon(for theib_srpkernel module)iwpmd(for iWARP kernel providers)ibacm(for InfiniBand communication management assistant)
COMPASS is a statistical framework that enables unbiased analysis of antigen-specific T-cell subsets. COMPASS uses a Bayesian hierarchical framework to model all observed cell-subsets and select the most likely to be antigen-specific while regularizing the small cell counts that often arise in multi-parameter space. The model provides a posterior probability of specificity for each cell subset and each sample, which can be used to profile a subject's immune response to external stimuli such as infection or vaccination.
BAYesian inference for MEDical designs in R. Functions for the computation of Bayes factors for common biomedical research designs. Implemented are functions to test the equivalence (equiv_bf), non-inferiority (infer_bf), and superiority (super_bf) of an experimental group compared to a control group on a continuous outcome measure, as well as functions for simulating survival data and calculating a Bayes factor for Cox proportional hazards models. Bayes factors for these tests can be computed based on raw data or summary statistics.
This package implements algorithms for analyzing Cayley graphs of permutation groups for the TopSpin puzzle. Provides methods for cycle detection, state space exploration and finding optimal operation sequences in permutation groups generated by shift and reverse operations. Also provides rule-defined landmark states for probing graphs too large to enumerate, and convex and non-convex hulls for measuring the solid such states span. The method Iterative Cycle Intersection (ICI) is described in Yuri Baramykov (2026) <doi:10.48550/arXiv.2607.13219>.
This package implements the deflist class, a read-only list-like object that accesses its elements via a function. The deflist class can be used to model deferred access to data or computations by routing indexed list access to a function. This approach is particularly useful when sequential list-like access to data is required but holding all the data in memory at once is not feasible. The package also provides utilities for memoisation and caching to optimize access to frequently requested elements.
Constructs data-derived graphs from numerical observations using mutual, shared-neighbor, intersection, geodesic, radius, adaptive-radius, and minimum-spanning-tree completion methods. Provides graph conversion, pruning, diagnostics, spectral embedding, endpoint detection, and path utilities. The implemented graph constructions include methods described by Jarvis and Patrick (1973) <doi:10.1109/T-C.1973.223640>, Brito et al. (1997) <doi:10.1016/S0167-7152(96)00213-1>, Berry and Sauer (2019) <doi:10.3934/fods.2019001>, and Gower and Ross (1969) <doi:10.2307/2346439>.
This package provides various statistical methods for evaluating heterogeneous treatment effects (HTE) in randomized experiments. The package includes tools to estimate uniform confidence bands for estimation of the group average treatment effect sorted by generic machine learning algorithms (GATES). It also provides the tools to identify a subgroup of individuals who are likely to benefit from a treatment the most "exceptional responders" or those who are harmed by it. Detailed reference in Imai and Li (2023) <doi:10.48550/arXiv.2310.07973>.