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Bayesian power/type I error calculation and model fitting using the power prior and the normalized power prior for generalized linear models. Detailed examples of applying the package are available at <doi:10.32614/RJ-2023-016>. Models for time-to-event outcomes are implemented in the R package BayesPPDSurv'. The Bayesian clinical trial design methodology is described in Chen et al. (2011) <doi:10.1111/j.1541-0420.2011.01561.x>, and Psioda and Ibrahim (2019) <doi:10.1093/biostatistics/kxy009>. The normalized power prior is described in Duan et al. (2006) <doi:10.1002/env.752> and Ibrahim et al. (2015) <doi:10.1002/sim.6728>.

Functional gradient descent algorithm for a variety of convex and non-convex loss functions, for both classical and robust regression and classification problems. See Wang (2011) <doi:10.2202/1557-4679.1304>, Wang (2012) <doi:10.3414/ME11-02-0020>, Wang (2018) <doi:10.1080/10618600.2018.1424635>, Wang (2018) <doi:10.1214/18-EJS1404>.

This package provides classes for storing and manipulating arbitrary-precision integer vectors and high-precision floating-point vectors. These extend the range and precision of the integer and double data types found in R. This package utilizes the Boost.Multiprecision C++ library. It is specifically designed to work well with the tidyverse collection of R packages.

The goal of BayesPower is to provide tools for Bayesian sample size determination and power analysis across a range of common hypothesis testing scenarios using Bayes factors. The main function, BayesPower_BayesFactor(), launches an interactive shiny application for performing these analyses. The application also provides command-line code for reproducibility. Details of the methods are described in the tutorial by Wong, Pawel, and Tendeiro (2025) <doi:10.31234/osf.io/pgdac_v3>.

Temporal Exponential Random Graph Models (TERGM) estimated by maximum pseudolikelihood with bootstrapped confidence intervals or Markov Chain Monte Carlo maximum likelihood. Goodness of fit assessment for ERGMs, TERGMs, and SAOMs. Micro-level interpretation of ERGMs and TERGMs. The methods are described in Leifeld, Cranmer and Desmarais (2018), JStatSoft <doi:10.18637/jss.v083.i06>.

Implementation of the BRIk, FABRIk and FDEBRIk algorithms to initialise k-means. These methods are intended for the clustering of multivariate and functional data, respectively. They make use of the Modified Band Depth and bootstrap to identify appropriate initial seeds for k-means, which are proven to be better options than many techniques in the literature. Torrente and Romo (2021) <doi:10.1007/s00357-020-09372-3> It makes use of the functions kma and kma.similarity, from the archived package fdakma, by Alice Parodi et al.

Analysis of relative cell type proportions in bulk gene expression data. Provides a well-validated set of brain cell type-specific marker genes derived from multiple types of experiments, as described in McKenzie (2018) <doi:10.1038/s41598-018-27293-5>. For brain tissue data sets, there are marker genes available for astrocytes, endothelial cells, microglia, neurons, oligodendrocytes, and oligodendrocyte precursor cells, derived from each of human, mice, and combination human/mouse data sets. However, if you have access to your own marker genes, the functions can be applied to bulk gene expression data from any tissue. Also implements multiple options for relative cell type proportion estimation using these marker genes, adapting and expanding on approaches from the CellCODE R package described in Chikina (2015) <doi:10.1093/bioinformatics/btv015>. The number of cell type marker genes used in a given analysis can be increased or decreased based on your preferences and the data set. Finally, provides functions to use the estimates to adjust for variability in the relative proportion of cell types across samples prior to downstream analyses.

Defines the functions used to compute the bimodal index as defined by Wang et al. (2009) <https://pmc.ncbi.nlm.nih.gov/articles/PMC2730180/>, <doi:10.4137/CIN.S2846>.

This package provides a Bayesian framework for Dynamic Energy Budget (DEB) modelling via Stan'. Implements the standard DEB model of Kooijman (2010, <doi:10.1017/CBO9780511805400>) as a state-space model with Hamiltonian Monte Carlo inference (Carpenter et al., 2017, <doi:10.18637/jss.v076.i01>). Includes individual-level growth models, growth-reproduction models, hierarchical multi-individual models with partial pooling, and toxicokinetic-toxicodynamic (TKTD) models for ecotoxicology following the DEBtox framework (Jager et al., 2006, <doi:10.1007/s10646-006-0060-x>). Supports prior specification from biological knowledge, convergence diagnostics (Vehtari et al., 2021, <doi:10.1214/20-BA1221>), posterior predictive checks, derived quantity estimation, and visualisation via ggplot2'.

Generic Extraction of main text content from HTML files; removal of ads, sidebars and headers using the boilerpipe <https://github.com/kohlschutter/boilerpipe> Java library. The extraction heuristics from boilerpipe show a robust performance for a wide range of web site templates.

This package provides tools for downloading historical financial data from the www.belex.rs.

Several specialized statistical tests and support functions for determining if numerical data could conform to Benford's law.

An interface for the Neo4j database providing mapping between different identifiers of biological entities. This Biological Entity Dictionary (BED) has been developed to address three main challenges. The first one is related to the completeness of identifier mappings. Indeed, direct mapping information provided by the different systems are not always complete and can be enriched by mappings provided by other resources. More interestingly, direct mappings not identified by any of these resources can be indirectly inferred by using mappings to a third reference. For example, many human Ensembl gene ID are not directly mapped to any Entrez gene ID but such mappings can be inferred using respective mappings to HGNC ID. The second challenge is related to the mapping of deprecated identifiers. Indeed, entity identifiers can change from one resource release to another. The identifier history is provided by some resources, such as Ensembl or the NCBI, but it is generally not used by mapping tools. The third challenge is related to the automation of the mapping process according to the relationships between the biological entities of interest. Indeed, mapping between gene and protein ID scopes should not be done the same way than between two scopes regarding gene ID. Also, converting identifiers from different organisms should be possible using gene orthologs information. The method has been published by Godard and van Eyll (2018) <doi:10.12688/f1000research.13925.3>.

This package provides advanced Bayesian methods to estimate abundance and run-timing from temporally-stratified Petersen mark-recapture experiments. Methods include hierarchical modelling of the capture probabilities and spline smoothing of the daily run size. Theory described in Bonner and Schwarz (2011) <doi:10.1111/j.1541-0420.2011.01599.x>.

This package provides an S4 class and methods for analyzing microbial social behavior in bacterial consortia. Includes growth parameter extraction, social behavior classification (cooperators/cheaters/neutrals), diversity effect analysis, consortium assembly path finding, and stability analysis via coefficient of variation. Methods are described in Purswani et al. (2017) <doi:10.3389/fmicb.2017.00919>.

Bayesian analysis of multivariate receptor modeling. The package consists of implementations of the methods of Park and Oh (2015) <doi:10.1016/j.chemolab.2015.08.021>.The package uses JAGS'(Just Another Gibbs Sampler) to generate Markov chain Monte Carlo samples of parameters.

This package provides a collection of models for bivariate alternating recurrent event data analysis. Includes non-parametric and semi-parametric methods.

Querying, extracting, and processing large-scale network data from Neo4j databases using the Neo4j Bolt <https://neo4j.com/docs/bolt/current/bolt/> protocol. This interface supports efficient data retrieval, batch processing for large datasets, and seamless conversion of query results into R data frames, making it ideal for bioinformatics, computational biology, and other graph-based applications.

Search and download data from the Swiss Federal Statistical Office (BFS) APIs <https://www.bfs.admin.ch/>.

Time series regression using dynamic linear models fit using MCMC. See Scott and Varian (2014) <DOI:10.1504/IJMMNO.2014.059942>, among many other sources.

The function estimates the hazard function non parametrically from a survival object (possibly adjusted for covariates). The smoothed estimate is based on B-splines from the perspective of generalized linear mixed models. Left truncated and right censoring data are allowed. The package is based on the work in Rebora P (2014) <doi:10.32614/RJ-2014-028>.

The binomialRF is a new feature selection technique for decision trees that aims at providing an alternative approach to identify significant feature subsets using binomial distributional assumptions (Rachid Zaim, S., et al. (2019)) <doi:10.1101/681973>. Treating each splitting variable selection as a set of exchangeable correlated Bernoulli trials, binomialRF then tests whether a feature is selected more often than by random chance.

Typically, models in R exist in memory and can be saved via regular R serialization. However, some models store information in locations that cannot be saved using R serialization alone. The goal of bundle is to provide a common interface to capture this information, situate it within a portable object, and restore it for use in new settings.