The kernelSmoothing() function allows you to square and smooth geolocated data. It calculates a classical kernel smoothing (conservative) or a geographically weighted median. There are four major call modes of the function. The first call mode is kernelSmoothing(obs, epsg, cellsize, bandwidth) for a classical kernel smoothing and automatic grid. The second call mode is kernelSmoothing(obs, epsg, cellsize, bandwidth, quantiles) for a geographically weighted median and automatic grid. The third call mode is kernelSmoothing(obs, epsg, cellsize, bandwidth, centroids) for a classical kernel smoothing and user grid. The fourth call mode is kernelSmoothing(obs, epsg, cellsize, bandwidth, quantiles, centroids) for a geographically weighted median and user grid. Geographically weighted summary statistics : a framework for localised exploratory data analysis, C.Brunsdon & al., in Computers, Environment and Urban Systems C.Brunsdon & al. (2002) <doi:10.1016/S0198-9715(01)00009-6>, Statistical Analysis of Spatial and Spatio-Temporal Point Patterns, Third Edition, Diggle, pp. 83-86, (2003) <doi:10.1080/13658816.2014.937718>.

This package provides methods for estimating the area under the concentration versus time curve (AUC) and its standard error in the presence of Below the Limit of Quantification (BLOQ) observations. Two approaches are implemented: direct estimation using censored maximum likelihood, and a two-step approach that first imputes BLOQ values using various methods and then computes the AUC using the imputed data. Technical details are described in Barnett et al. (2020), "Methods for Non-Compartmental Pharmacokinetic Analysis With Observations Below the Limit of Quantification," Statistics in Biopharmaceutical Research. <doi:10.1080/19466315.2019.1701546>.

Bayesian analysis for exponential random graph models using advanced computational algorithms. More information can be found at: <https://acaimo.github.io/Bergm/>.

The BayesDLMfMRI package performs statistical analysis for task-based functional magnetic resonance imaging (fMRI) data at both individual and group levels. The analysis to detect brain activation at the individual level is based on modeling the fMRI signal using Matrix-Variate Dynamic Linear Models (MDLM). The analysis for the group stage is based on posterior distributions of the state parameter obtained from the modeling at the individual level. In this way, this package offers several R functions with different algorithms to perform inference on the state parameter to assess brain activation for both individual and group stages. Those functions allow for parallel computation when the analysis is performed for the entire brain as well as analysis at specific voxels when it is required. References: Cardona-Jiménez (2021) <doi:10.1016/j.csda.2021.107297>; Cardona-Jiménez (2021) <arXiv:2111.01318>.

Generate urls and hyperlinks to commonly used biological databases and resources based on standard identifiers. This is primarily useful when writing dynamic reports that reference things like gene symbols in text or tables, allowing you to, for example, convert gene identifiers to hyperlinks pointing to their entry in the NCBI Gene database. Currently supports NCBI Gene, PubMed', Gene Ontology, KEGG', CRAN and Bioconductor.

This package provides functions to allow you to easily pass command-line arguments into R, and functions to aid in submitting your R code in parallel on a cluster and joining the results afterward (e.g. multiple parameter values for simulations running in parallel, splitting up a permutation test in parallel, etc.). See `parseCommandArgs(...) for the main example of how to use this package.

This package provides a Bayesian regression model for discrete response, where the conditional distribution is modelled via a discrete Weibull distribution. This package provides an implementation of Metropolis-Hastings and Reversible-Jumps algorithms to draw samples from the posterior. It covers a wide range of regularizations through any two parameter prior. Examples are Laplace (Lasso), Gaussian (ridge), Uniform, Cauchy and customized priors like a mixture of priors. An extensive visual toolbox is included to check the validity of the results as well as several measures of goodness-of-fit.

Enables off-the-shelf functionality for fully Bayesian, nonstationary Gaussian process modeling. The approach to nonstationary modeling involves a closed-form, convolution-based covariance function with spatially-varying parameters; these parameter processes can be specified either deterministically (using covariates or basis functions) or stochastically (using approximate Gaussian processes). Stationary Gaussian processes are a special case of our methodology, and we furthermore implement approximate Gaussian process inference to account for very large spatial data sets (Finley, et al (2017) <arXiv:1702.00434v2>). Bayesian inference is carried out using Markov chain Monte Carlo methods via the nimble package, and posterior prediction for the Gaussian process at unobserved locations is provided as a post-processing step.

This package provides a collection of functions allowing to derive the posterior distribution of the model parameters in random-effects meta-analysis or meta-regression, and providing functionality to evaluate joint and marginal posterior probability distributions, predictive distributions, shrinkage effects, posterior predictive p-values, etc.; For more details, see also Roever C (2020) <doi:10.18637/jss.v093.i06>, or Roever C and Friede T (2022) <doi:10.1016/j.cmpb.2022.107303>.

Generating multiple binary and normal variables simultaneously given marginal characteristics and association structure based on the methodology proposed by Demirtas and Doganay (2012) <DOI:10.1080/10543406.2010.521874>.

This package provides methods for mediation analysis with missing data and non-normal data are implemented. For missing data, four methods are available: Listwise deletion, Pairwise deletion, Multiple imputation, and Two Stage Maximum Likelihood algorithm. For MI and TS-ML, auxiliary variables can be included to handle missing data. For handling non-normal data, bootstrap and two-stage robust methods can be used. Technical details of the methods can be found in Zhang and Wang (2013, <doi:10.1007/s11336-012-9301-5>), Zhang (2014, <doi:10.3758/s13428-013-0424-0>), and Yuan and Zhang (2012, <doi:10.1007/s11336-012-9282-4>).

Full Bayesian estimation of Multidimensional Generalized Graded Unfolding Model (MGGUM) using rstan (See Stan Development Team (2020) <https://mc-stan.org/>). Functions are provided for estimation, result extraction, model fit statistics, and plottings.

Bayes screening and model discrimination follow-up designs.

This package provides a framework and toolkit to guide shiny developers in implementing the Behavioral Insight Design (BID) framework. The package offers functions for documenting each of the five stages (Interpret, Notice, Anticipate, Structure, and Validate), along with a comprehensive concept dictionary.

This package creates bivariate choropleth maps using Leaflet'. This package provides tools for visualizing the relationship between two variables through a color matrix representation on an interactive map.

The Super Imposition by Translation and Rotation (SITAR) model is a shape-invariant nonlinear mixed effect model that fits a natural cubic spline mean curve to the growth data and aligns individual-specific growth curves to the underlying mean curve via a set of random effects (see Cole, 2010 <doi:10.1093/ije/dyq115> for details). The non-Bayesian version of the SITAR model can be fit by using the already available R package sitar'. While the sitar package allows modelling of a single outcome only, the bsitar package offers great flexibility in fitting models of varying complexities, including joint modelling of multiple outcomes such as height and weight (multivariate model). Additionally, the bsitar package allows for the simultaneous analysis of an outcome separately for subgroups defined by a factor variable such as gender. This is achieved by fitting separate models for each subgroup (for example males and females for gender variable). An advantage of this approach is that posterior draws for each subgroup are part of a single model object, making it possible to compare coefficients across subgroups and test hypotheses. Since the bsitar package is a front-end to the R package brms', it offers excellent support for post-processing of posterior draws via various functions that are directly available from the brms package. In addition, the bsitar package includes various customized functions that allow for the visualization of distance (increase in size with age) and velocity (change in growth rate as a function of age), as well as the estimation of growth spurt parameters such as age at peak growth velocity and peak growth velocity.

Allows local bone density estimates to be derived from CT data and mapped to 3D bone models in a reproducible manner. Processing can be performed at the individual bone or group level. Also includes tools for visualizing the bone density estimates. Example methods are described in Telfer et al., (2021) <doi:10.1002/jor.24792>, Telfer et al., (2021) <doi:10.1016/j.jse.2021.05.011>.

Generic Extraction of main text content from HTML files; removal of ads, sidebars and headers using the boilerpipe <https://github.com/kohlschutter/boilerpipe> Java library. The extraction heuristics from boilerpipe show a robust performance for a wide range of web site templates.

Computation of bootstrap confidence intervals in an almost automatic fashion as described in Efron and Narasimhan (2020, <doi:10.1080/10618600.2020.1714633>).

Provide early termination phase II trial designs with a decreasingly informative prior (DIP) or a regular Bayesian prior chosen by the user. The program can determine the minimum planned sample size necessary to achieve the user-specified admissible designs. The program can also perform power and expected sample size calculations for the tests in early termination Phase II trials. See Wang C and Sabo RT (2022) <doi:10.18203/2349-3259.ijct20221110>; Sabo RT (2014) <doi:10.1080/10543406.2014.888441>.

Extract, visualize and summarize aerial movements of birds and insects from weather radar data. See Dokter, A. M. et al. (2018) "bioRad: biological analysis and visualization of weather radar data" <doi:10.1111/ecog.04028> for a software paper describing package and methodologies.

This package provides tools for the analysis of replication studies using Bayes factors (Pawel and Held, 2022) <doi:10.1111/rssb.12491>.

Perform change points detection on univariate and multivariate time series according to the methods presented by Asael Fabian Martà nez and Ramsés H. Mena (2014) <doi:10.1214/14-BA878> and Corradin, Danese and Ongaro (2022) <doi:10.1016/j.ijar.2021.12.019>. It also clusters different types of time dependent data with common change points, see "Model-based clustering of time-dependent observations with common structural changes" (Corradin,Danese,KhudaBukhsh and Ongaro, 2024) <doi:10.48550/arXiv.2410.09552> for details.

Reads several formats of 13C data (IRIS/Wagner, BreathID) and CSV. Creates artificial sample data for testing. Fits Maes/Ghoos, Bluck-Coward self-correcting formula using nls', nlme'. Methods to fit breath test curves with Bayesian Stan methods are refactored to package breathteststan'. For a Shiny GUI, see package dmenne/breathtestshiny on github.