Clinical trial design for subgroup selection in three-stage group sequential trial as described in Lai, Lavori and Liao (2014, <doi:10.1016/j.cct.2014.09.001>). Includes facilities for design, exploration and analysis of such trials. An implementation of the initial DEFUSE-3 trial is also provided as a vignette.

Create American Psychological Association Style, Seventh Edition documents. Format numbers and text consistent with APA style. Create tables that comply with APA style by extending flextable functions.

Auto-GO is a framework that enables automated, high quality Gene Ontology enrichment analysis visualizations. It also features a handy wrapper for Differential Expression analysis around the DESeq2 package described in Love et al. (2014) <doi:10.1186/s13059-014-0550-8>. The whole framework is structured in different, independent functions, in order to let the user decide which steps of the analysis to perform and which plot to produce.

Lets you open a fixed-width ASCII file (.txt or .dat) that has an accompanying setup file (.sps or .sas). These file combinations are sometimes referred to as .txt+.sps, .txt+.sas, .dat+.sps, or .dat+.sas. This will only run in a txt-sps or txt-sas pair in which the setup file contains instructions to open that text file. It will NOT open other text files, .sav, .sas, or .por data files. Fixed-width ASCII files with setup files are common in older (pre-2000) government data.

This package implements the Classification-based on Association Rules (CBA) algorithm for association rule classification. The package, also described in Hahsler et al. (2019) <doi:10.32614/RJ-2019-048>, contains several convenience methods that allow to automatically set CBA parameters (minimum confidence, minimum support) and it also natively handles numeric attributes by integrating a pre-discretization step. The rule generation phase is handled by the arules package. To further decrease the size of the CBA models produced by the arc package, postprocessing by the qCBA package is suggested.

Provides: (1) Tools to infer dominance hierarchies based on calculating Elo scores, but with custom functions to improve estimates in animals with relatively stable dominance ranks. (2) Tools to plot the shape of the dominance hierarchy and estimate the uncertainty of a given data set.

This package provides tools for constructing a matched design with multiple comparison groups. Further specifications of refined covariate balance restriction and exact match on covariate can be imposed. Matches are approximately optimal in the sense that the cost of the solution is at most twice the optimal cost, Crama and Spieksma (1992) <doi:10.1016/0377-2217(92)90078-N>, Karmakar, Small and Rosenbaum (2019) <doi:10.1080/10618600.2019.1584900>.

Set of tools for fitting the additive partial linear models with symmetric autoregressive errors of order p, or APLMS-AR(p). This setup enables the modeling of a time series response variable using linear and nonlinear structures of a set of explanatory variables, with nonparametric components approximated by natural cubic splines or P-splines. It also accounts for autoregressive error terms with distributions that have lighter or heavier tails than the normal distribution. The package includes various error distributions, such as normal, generalized normal, Student's t, generalized Student's t, power-exponential, and Cauchy distributions. Chou-Chen, S.W., Oliveira, R.A., Raicher, I., Gilberto A. Paula (2024) <doi:10.1007/s00362-024-01590-w>.

Interactive graphical user interface (GUI) for the package AdhereR', allowing the user to access different data sources, to explore the patterns of medication use therein, and the computation of various measures of adherence. It is implemented using Shiny and HTML/CSS/JavaScript.

Perform one-dimensional spline regression with automatic knot selection. This package uses a penalized approach to select the most relevant knots. B-splines of any degree can be fitted. More details in Goepp et al. (2018)', "Spline Regression with Automatic Knot Selection", <arXiv:1808.01770>.

A-priori power simulations and power-calculations for within, between and mixed ANOVAs based on target (partial) eta-squared values. Supports complex designs with more than two factors and their interactions with a single function call.

Comprehensive toolkit for reading and analyzing Anki flashcard collection databases. Provides functions to access notes, cards, decks, note types, and review logs with a tidy interface. Features extensive analytics including retention rates, learning curves, forgetting curve fitting, and review patterns. Supports FSRS (Free Spaced Repetition Scheduler) analysis with stability, difficulty, retrievability metrics, parameter comparison, and workload predictions. Includes visualization functions, comparative analysis, time-based analytics, card quality assessment, sibling card analysis, interference detection, predictive features, session simulation, and an interactive Shiny dashboard. Academic/exam preparation tools for medical students and board exam preparation. Export capabilities include CSV, Org-mode, Markdown, SuperMemo, Mochi, Obsidian SR, and JSON formats with progress reports.

This package provides different functionalities and calculations used in the world of basketball to analyze the statistics of the players, the statistics of the teams, the statistics of the quintets and the statistics of the plays. For more details of the calculations included in the package can be found in the book Basketball on Paper written by Dean Oliver.

This package provides tools to study sorting patterns in matching markets and to estimate the affinity matrix of both the bipartite one-to-one matching model without frictions and with Transferable Utility by Dupuy and Galichon (2014) <doi:10.1086/677191> and its unipartite variant by Ciscato', Galichon and Gousse (2020) <doi:10.1086/704611>. It also contains all the necessary tools to implement the saliency analysis, to run rank tests of the affinity matrix and to build tables and plots summarizing the findings.

This package performs the analysis of completely randomized experimental designs (CRD), randomized blocks (RBD) and Latin square (LSD), experiments in double and triple factorial scheme (in CRD and RBD), experiments in subdivided plot scheme (in CRD and RBD), subdivided and joint analysis of experiments in CRD and RBD, linear regression analysis, test for two samples. The package performs analysis of variance, ANOVA assumptions and multiple comparison test of means or regression, according to Pimentel-Gomes (2009, ISBN: 978-85-7133-055-9), nonparametric test (Conover, 1999, ISBN: 0471160687), test for two samples, joint analysis of experiments according to Ferreira (2018, ISBN: 978-85-7269-566-4) and generalized linear model (glm) for binomial and Poisson family in CRD and RBD (Carvalho, FJ (2019), <doi:10.14393/ufu.te.2019.1244>). It can also be used to obtain descriptive measures and graphics, in addition to correlations and creative graphics used in agricultural sciences (Agronomy, Zootechnics, Food Science and related areas). Shimizu, G. D., Marubayashi, R. Y. P., Goncalves, L. S. A. (2025) <doi:10.4025/actasciagron.v47i1.73889>.

Named after the Irish name for weather, this package contains tidied data from the Irish Meteorological Service's hourly observations for 2017. In all, the data sets include observations from 25 weather stations, and also latitude and longitude coordinates for each weather station. Now includes energy generation data for Ireland and Northern Ireland (2017), including Wind Generation data.

This package provides a simple interface to the instance metadata for a virtual machine running in Microsoft's Azure cloud. This provides information about the VM's configuration, such as its processors, memory, networking, storage, and so on. Part of the AzureR family of packages.

This package provides a set of functions for interacting with the DigitalOcean API <https://www.digitalocean.com/>, including creating images, destroying them, rebooting, getting details on regions, and available images.

Causal discovery in linear structural equation models (Schultheiss, and Bühlmann (2023) <doi:10.1093/biomet/asad008>) and vector autoregressive models (Schultheiss, Ulmer, and Bühlmann (2025) <doi:10.1515/jci-2024-0011>) with explicit error control for false discovery, at least asymptotically.

Connect to the Adobe Analytics API v2.0 <https://github.com/AdobeDocs/analytics-2.0-apis> which powers Analysis Workspace'. The package was developed with the analyst in mind, and it will continue to be developed with the guiding principles of iterative, repeatable, timely analysis.

Facilitates plotting audiometric data (mostly) by preparing the coordinate system according to standards, given e. g. in American Speech-Language-Hearing Association (2005), <doi:10.1044/policy.GL2005-00014>.

This package provides a spatiotemporal model that simulates the spread of Ascochyta blight in chickpea fields based on location-specific weather conditions. This model is adapted from a model developed by Diggle et al. (2002) <doi:10.1094/PHYTO.2002.92.10.1110> for simulating the spread of anthracnose in a lupin field.

With appRiori <doi:10.1177/25152459241293110>, users upload the research variables and the app guides them to the best set of comparisons fitting the hypotheses, for both main and interaction effects. Through a graphical explanation and empirical examples on reproducible data, it is shown that it is possible to understand both the logic behind the planned comparisons and the way to interpret them when a model is tested.

This package provides an automatic aggregation tool to manage point data privacy, intended to be helpful for the production of official spatial data and for researchers. The package pursues the data accuracy at the smallest possible areas preventing individual information disclosure. The methodology, based on hierarchical geographic data structures performs aggregation and local suppression of point data to ensure privacy as described in Lagonigro, R., Oller, R., Martori J.C. (2017) <doi:10.2436/20.8080.02.55>. The data structures are created following the guidelines for grid datasets from the European Forum for Geography and Statistics.