This package contains Bayesian implementations of the Mixed-Effects Accelerated Failure Time (MEAFT) models for censored data. Those can be not only right-censored but also interval-censored, doubly-interval-censored or misclassified interval-censored. The methods implemented in the package have been published in Komárek and Lesaffre (2006, Stat. Modelling) <doi:10.1191/1471082X06st107oa>, Komárek, Lesaffre and Legrand (2007, Stat. in Medicine) <doi:10.1002/sim.3083>, Komárek and Lesaffre (2007, Stat. Sinica) <https://www3.stat.sinica.edu.tw/statistica/oldpdf/A17n27.pdf>, Komárek and Lesaffre (2008, JASA) <doi:10.1198/016214507000000563>, Garcà a-Zattera, Jara and Komárek (2016, Biometrics) <doi:10.1111/biom.12424>.

It computes betas-select, coefficients after standardization in structural equation models and regression models, standardizing only selected variables. Supports models with moderation, with product terms formed after standardization. It also offers confidence intervals that account for standardization, including bootstrap confidence intervals as proposed by Cheung et al. (2022) <doi:10.1037/hea0001188>.

This package provides access to a range of functions for analyzing, applying and visualizing Bayesian response-adaptive trial designs for a binary endpoint. Includes the predictive probability approach and the predictive evidence value designs for binary endpoints.

Fit computational and measurement models using full Bayesian inference. The package provides a simple and accessible interface by translating complex domain-specific models into brms syntax, a powerful and flexible framework for fitting Bayesian regression models using Stan'. The package is designed so that users can easily apply state-of-the-art models in various research fields, and so that researchers can use it as a new model development framework. References: Frischkorn and Popov (2023) <doi:10.31234/osf.io/umt57>.

This package provides a simple tool to quantify the amount of transmission of an infectious disease of interest occurring within and between population groups. bumblebee uses counts of observed directed transmission pairs, identified phylogenetically from deep-sequence data or from epidemiological contacts, to quantify transmission flows within and between population groups accounting for sampling heterogeneity. Population groups might include: geographical areas (e.g. communities, regions), demographic groups (e.g. age, gender) or arms of a randomized clinical trial. See the bumblebee website for statistical theory, documentation and examples <https://magosil86.github.io/bumblebee/>.

This package provides the facility to calculate the Brainerd-Robinson similarity coefficient for the rows of an input table, and to calculate the significance of each coefficient based on a permutation approach; a heatmap is produced to visually represent the similarity matrix. Optionally, hierarchical agglomerative clustering can be performed and the silhouette method is used to identify an optimal number of clusters; the results of the clustering can be optionally used to sort the heatmap.

Enables off-the-shelf functionality for fully Bayesian, nonstationary Gaussian process modeling. The approach to nonstationary modeling involves a closed-form, convolution-based covariance function with spatially-varying parameters; these parameter processes can be specified either deterministically (using covariates or basis functions) or stochastically (using approximate Gaussian processes). Stationary Gaussian processes are a special case of our methodology, and we furthermore implement approximate Gaussian process inference to account for very large spatial data sets (Finley, et al (2017) <doi:10.48550/arXiv.1702.00434>). Bayesian inference is carried out using Markov chain Monte Carlo methods via the "nimble" package, and posterior prediction for the Gaussian process at unobserved locations is provided as a post-processing step.

This package provides functions for training an optimal decision tree classifier, making predictions and generating latex code for plotting. Works for two-class and multi-class classification problems. The algorithm seeks the optimal Boolean rule consisting of multiple variables to split a node, resulting in shorter trees. Use bsnsing() to build a tree, predict() to make predictions and plot() to plot the tree into latex and PDF. See Yanchao Liu (2022) <arXiv:2205.15263> for technical details. Source code and more data sets are at <https://github.com/profyliu/bsnsing/>.

Co-clustering of the rows and columns of a contingency or binary matrix, or double binary matrices and model selection for the number of row and column clusters. Three models are considered: the Poisson latent block model for contingency matrix, the binary latent block model for binary matrix and a new model we develop: the multiple latent block model for double binary matrices. A new procedure named bikm1 is implemented to investigate more efficiently the grid of numbers of clusters. Then, the studied model selection criteria are the integrated completed likelihood (ICL) and the Bayesian integrated likelihood (BIC). Finally, the co-clustering adjusted Rand index (CARI) to measure agreement between co-clustering partitions is implemented. Robert Valerie, Vasseur Yann, Brault Vincent (2021) <doi:10.1007/s00357-020-09379-w>.

Developed for the following tasks. Simulating, computing maximum likelihood estimator, computing the Fisher information matrix, computing goodness-of-fit measures, and correcting bias of the ML estimator for a wide range of distributions fitted to units placed on progressive type-I interval censoring and progressive type-II censoring plans. The methods of Cox and Snell (1968) <doi:10.1111/j.2517-6161.1968.tb00724.x> and bootstrap method for computing the bias-corrected maximum likelihood estimator.

This package provides a fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

Fits smoothing spline regression models using scalable algorithms designed for large samples. Seven marginal spline types are supported: linear, cubic, different cubic, cubic periodic, cubic thin-plate, ordinal, and nominal. Random effects and parametric effects are also supported. Response can be Gaussian or non-Gaussian: Binomial, Poisson, Gamma, Inverse Gaussian, or Negative Binomial.

This package provides a way to reduce model objects to necessary parts, making them easier to work with, store, share and simulate multiple values for new responses while allowing for parameter uncertainty.

This package contains tools to fit both predictive and prognostic biomarker effects using biomarker threshold models and continuous threshold models. Evaluate the treatment effect, biomarker effect and treatment-biomarker interaction using probability index measurement. Test for treatment-biomarker interaction using residual bootstrap method.

This package provides a class of Bayesian beta regression models for the analysis of continuous data with support restricted to an unknown finite support. The response variable is modeled using a four-parameter beta distribution with the mean or mode parameter depending linearly on covariates through a link function. When the response support is known to be (0,1), the above class of models reduce to traditional (0,1) supported beta regression models. Model choice is carried out via the logarithm of the pseudo marginal likelihood (LPML), the deviance information criterion (DIC), and the Watanabe-Akaike information criterion (WAIC). See Zhou and Huang (2022) <doi:10.1016/j.csda.2021.107345>.

Decomposition for differences-in-differences with variation in treatment timing from Goodman-Bacon (2018) <doi:10.3386/w25018>.

Finds the largest possible regression model that will still converge for various types of regression analyses (including mixed models and generalized additive models) and then optionally performs stepwise elimination similar to the forward and backward effect-selection methods in SAS, based on the change in log-likelihood or its significance, Akaike's Information Criterion, the Bayesian Information Criterion, the explained deviance, or the F-test of the change in R².

Complex machine learning models are often difficult to interpret. Shapley values serve as a powerful tool to understand and explain why a model makes a particular prediction. This package computes variable contributions using permutation-based Shapley values for Bayesian Additive Regression Trees (BART) and its extension with Post-Stratification (BARP). The permutation-based SHAP method proposed by Strumbel and Kononenko (2014) <doi:10.1007/s10115-013-0679-x> is grounded in data obtained via MCMC sampling. Similar to the BART model introduced by Chipman, George, and McCulloch (2010) <doi:10.1214/09-AOAS285>, this package leverages Bayesian posterior samples generated during model estimation, allowing variable contributions to be computed without requiring additional sampling. The BART model is designed to work with the following R packages: BART <doi:10.18637/jss.v097.i01>, bartMachine <doi:10.18637/jss.v070.i04>, and dbarts <https://CRAN.R-project.org/package=dbarts>. For XGBoost and baseline adjustments, the approach by Lundberg et al. (2020) <doi:10.1038/s42256-019-0138-9> is also considered. The BARP model proposed by Bisbee (2019) <doi:10.1017/S0003055419000480> was implemented with reference to <https://github.com/jbisbee1/BARP> and is designed to work with modified functions based on that implementation. BARP extends post-stratification by computing variable contributions within each stratum defined by stratifying variables. The resulting Shapley values are visualized through both global and local explanation methods.

Real-time quantitative polymerase chain reaction (qPCR) data sets by Batsch et al. (2008) <doi:10.1186/1471-2105-9-95>. This package provides five data sets, one for each PCR target: (i) rat SLC6A14, (ii) human SLC22A13, (iii) pig EMT, (iv) chicken ETT, and (v) human GAPDH. Each data set comprises a five-point, four-fold dilution series. For each concentration there are three replicates. Each amplification curve is 45 cycles long. Original raw data file: <https://static-content.springer.com/esm/art%3A10.1186%2F1471-2105-9-95/MediaObjects/12859_2007_2080_MOESM5_ESM.xls>.

Simultaneously clusters the Periodontal diseases (PD) patients and their tooth sites after taking the patient- and site-level covariates into consideration. BAREB uses the determinantal point process (DPP) prior to induce diversity among different biclusters to facilitate parsimony and interpretability. Essentially, BAREB is a cluster-wise linear model based on Yuliang (2020) <doi:10.1002/sim.8536>.

Bayes factors represent the ratio of probabilities assigned to data by competing scientific hypotheses. However, one drawback of Bayes factors is their dependence on prior specifications that define null and alternative hypotheses. Additionally, there are challenges in their computation. To address these issues, we define Bayes factor functions (BFFs) directly from common test statistics. BFFs express Bayes factors as a function of the prior densities used to define the alternative hypotheses. These prior densities are centered on standardized effects, which serve as indices for the BFF. Therefore, BFFs offer a summary of evidence in favor of alternative hypotheses that correspond to a range of scientifically interesting effect sizes. Such summaries remove the need for arbitrary thresholds to determine "statistical significance." BFFs are available in closed form and can be easily computed from z, t, chi-squared, and F statistics. They depend on hyperparameters "r" and "tau^2", which determine the shape and scale of the prior distributions defining the alternative hypotheses. Plots of BFFs versus effect size provide informative summaries of hypothesis tests that can be easily aggregated across studies.

This package implements z-test, t-test, and normal moment prior Bayes factors based on summary statistics, along with functionality to perform corresponding power and sample size calculations as described in Pawel and Held (2025) <doi:10.1080/00031305.2025.2467919>.

This package provides functions to reconstruct, generate, and simulate synchronous, asynchronous, probabilistic, and temporal Boolean networks. Provides also functions to analyze and visualize attractors in Boolean networks <doi:10.1093/bioinformatics/btq124>.

This package provides a "Shiny"" web application for creating interactive Bayesian Network models, learning the structure and parameters of Bayesian networks, and utilities for classic network analysis.