This package provides tools to create, validate, and export BioCompute Objects described in King et al. (2019) <doi:10.17605/osf.io/h59uh>. Users can encode information in data frames, and compose BioCompute Objects from the domains defined by the standard. A checksum validator and a JSON schema validator are provided. This package also supports exporting BioCompute Objects as JSON, PDF, HTML, or Word documents, and exporting to cloud-based platforms.

This package provides a backward-pipe operator for magrittr (%<%) or pipeR (%<<%) that allows for a performing operations from right-to-left. This allows writing more legible code where right-to-left ordering is natural. This is common with hierarchies and nested structures such as trees, directories or markup languages (e.g. HTML and XML). The package also includes a R-Studio add-in that can be bound to a keyboard shortcut.

Generation of correlated artificial binary data.

Retrieve and import data from the INKAR database (Indikatoren und Karten zur Raum- und Stadtentwicklung Datenbank, <https://www.inkar.de>) of the Federal Office for Building and Regional Planning (BBSR) in Bonn using their JSON API.

Call the data wrappers for Bursa Metropolitan Municipality's Open Data Portal <https://acikyesil.bursa.bel.tr/>. This will return all datasets stored in different formats.

This package provides a framework for data manipulation and visualization using a web-based point and click user interface where analysis pipelines are decomposed into re-usable and parameterizable blocks.

This is a sub national population projection model for calculating population development. The model uses a cohort component method. Further reading: Stanley K. Smith: A Practitioner's Guide to State and Local Population Projections. 2013. <doi:10.1007/978-94-007-7551-0>.

Infrastructure for estimating probabilistic distributional regression models in a Bayesian framework. The distribution parameters may capture location, scale, shape, etc. and every parameter may depend on complex additive terms (fixed, random, smooth, spatial, etc.) similar to a generalized additive model. The conceptual and computational framework is introduced in Umlauf, Klein, Zeileis (2019) <doi:10.1080/10618600.2017.1407325> and the R package in Umlauf, Klein, Simon, Zeileis (2021) <doi:10.18637/jss.v100.i04>.

Enable users to evaluate long-term trends using a Generalized Additive Modeling (GAM) approach. The model development includes selecting a GAM structure to describe nonlinear seasonally-varying changes over time, incorporation of hydrologic variability via either a river flow or salinity, the use of an intervention to deal with method or laboratory changes suspected to impact data values, and representation of left- and interval-censored data. The approach has been applied to water quality data in the Chesapeake Bay, a major estuary on the east coast of the United States to provide insights to a range of management- and research-focused questions. Methodology described in Murphy (2019) <doi:10.1016/j.envsoft.2019.03.027>.

This package performs Bayesian variable screening and selection for ultra-high dimensional linear regression models.

This package provides a Bayesian version of the analysis of variance based on a three-component Gaussian mixture for which a Gibbs sampler produces posterior draws. For details about the Bayesian ANOVA based on Gaussian mixtures, see Kelter (2019) <arXiv:1906.07524>.

This package provides a collection of functions for structure learning of causal networks and estimation of joint causal effects from observational Gaussian data. Main algorithm consists of a Markov chain Monte Carlo scheme for posterior inference of causal structures, parameters and causal effects between variables. References: F. Castelletti and A. Mascaro (2021) <doi:10.1007/s10260-021-00579-1>, F. Castelletti and A. Mascaro (2022) <doi:10.48550/arXiv.2201.12003>.

Build decision trees and random forests for classification and regression. The implementation strikes a balance between minimizing computing efforts and maximizing the expected predictive accuracy, thus scales well to large data sets. Multi-threading is available through OpenMP <https://gcc.gnu.org/wiki/openmp>.

This package contains tools for survey statistics (especially in educational assessment) for datasets with replication designs (jackknife, bootstrap, replicate weights; see Kolenikov, 2010; Pfefferman & Rao, 2009a, 2009b, <doi:10.1016/S0169-7161(09)70003-3>, <doi:10.1016/S0169-7161(09)70037-9>); Shao, 1996, <doi:10.1080/02331889708802523>). Descriptive statistics, linear and logistic regression, path models for manifest variables with measurement error correction and two-level hierarchical regressions for weighted samples are included. Statistical inference can be conducted for multiply imputed datasets and nested multiply imputed datasets and is in particularly suited for the analysis of plausible values (for details see George, Oberwimmer & Itzlinger-Bruneforth, 2016; Bruneforth, Oberwimmer & Robitzsch, 2016; Robitzsch, Pham & Yanagida, 2016). The package development was supported by BIFIE (Federal Institute for Educational Research, Innovation and Development of the Austrian School System; Salzburg, Austria).

Compute Buishand Range Test, Pettit Test, SNHT, Student t-test, and Mann-Whitney Rank Test, to identify breakpoints in series. For all functions NA is allowed. Since all of the mention methods identify only one breakpoint in a series, a general function to look for N breakpoint is given. Also, the Yamamoto test for climate jump is available. Alexandersson, H. (1986) <doi:10.1002/joc.3370060607>, Buishand, T. (1982) <doi:10.1016/0022-1694(82)90066-X>, Hurtado, S. I., Zaninelli, P. G., & Agosta, E. A. (2020) <doi:10.1016/j.atmosres.2020.104955>, Mann, H. B., Whitney, D. R. (1947) <doi:10.1214/aoms/1177730491>, Pettitt, A. N. (1979) <doi:10.2307/2346729>, Ruxton, G. D., jul (2006) <doi:10.1093/beheco/ark016>, Yamamoto, R., Iwashima, T., Kazadi, S. N., & Hoshiai, M. (1985) <doi:10.2151/jmsj1965.63.6_1157>.

This package provides a chemical speciation and toxicity prediction model for the toxicity of metals to aquatic organisms. The Biotic Ligand Model (BLM) engine was originally programmed in PowerBasic by Robert Santore and others. The main way the BLM can be used is to predict the toxicity of a metal to an organism with a known sensitivity (i.e., it is known how much of that metal must accumulate on that organism's biotic ligand to cause a physiological effect in a certain percentage of the population, such as a 20% loss in reproduction or a 50% mortality rate). The second way the BLM can be used is to estimate the chemical speciation of the metal and other constituents in water, including estimating the amount of metal accumulated to an organism's biotic ligand during a toxicity test. In the first application of the BLM, the amount of metal associated with a toxicity endpoint, or regulatory limit will be predicted, while in the second application, the amount of metal is known and the portions of that metal that exist in various forms will be determined. This version of the engine has been re-structured to perform the calculations in a different way that will make it more efficient in R, while also making it more flexible and easier to maintain in the future. Because of this, it does not currently match the desktop model exactly, but we hope to improve this comparability in the future.

Enables the user to infer potential synthetic lethal relationships by analysing relationships between bimodally distributed gene pairs in big gene expression datasets. Enables the user to visualise these candidate synthetic lethal relationships.

Toolkit for Bayesian estimation of the dependence structure in multivariate extreme value parametric models, following Sabourin and Naveau (2014) <doi:10.1016/j.csda.2013.04.021> and Sabourin, Naveau and Fougeres (2013) <doi:10.1007/s10687-012-0163-0>.

This package provides tools for fitting Bayesian single index models with flexible choices of priors for both the index and the link function. The package implements model estimation and posterior inference using efficient MCMC algorithms built on the nimble framework, allowing users to specify, extend, and simulate models in a unified and reproducible manner. The following methods are implemented in the package: Antoniadis et al. (2004) <https://www.jstor.org/stable/24307224>, Wang (2009) <doi:10.1016/j.csda.2008.12.010>, Choi et al. (2011) <doi:10.1080/10485251003768019>, Dhara et al. (2019) <doi:10.1214/19-BA1170>, McGee et al. (2023) <doi:10.1111/biom.13569>.

Estimates VAR and VARX models with Structured Penalties.

This package provides functions to access data from the BrasilAPI', REST Countries API', Nager.Date API', and World Bank API', related to Brazil's postal codes, banks, holidays, company registrations, international country indicators, public holidays information, and economic development data. Additionally, the package includes curated datasets related to Brazil, covering topics such as demographic data (males and females by state and year), river levels, environmental emission factors, film festivals, and yellow fever outbreak records. The package supports research and analysis focused on Brazil by integrating open APIs with high-quality datasets from multiple domains. For more information on the APIs, see: BrasilAPI <https://brasilapi.com.br/>, Nager.Date <https://date.nager.at/Api>, World Bank API <https://datahelpdesk.worldbank.org/knowledgebase/articles/889392>, and REST Countries API <https://restcountries.com/>.

Efficient methods for Bayesian inference of state space models via Markov chain Monte Carlo (MCMC) based on parallel importance sampling type weighted estimators (Vihola, Helske, and Franks, 2020, <doi:10.1111/sjos.12492>), particle MCMC, and its delayed acceptance version. Gaussian, Poisson, binomial, negative binomial, and Gamma observation densities and basic stochastic volatility models with linear-Gaussian state dynamics, as well as general non-linear Gaussian models and discretised diffusion models are supported. See Helske and Vihola (2021, <doi:10.32614/RJ-2021-103>) for details.

Perform mediation analysis in the presence of high-dimensional mediators based on the potential outcome framework. Bayesian Mediation Analysis (BAMA), developed by Song et al (2019) <doi:10.1111/biom.13189> and Song et al (2020) <doi:10.48550/arXiv.2009.11409>, relies on two Bayesian sparse linear mixed models to simultaneously analyze a relatively large number of mediators for a continuous exposure and outcome assuming a small number of mediators are truly active. This sparsity assumption also allows the extension of univariate mediator analysis by casting the identification of active mediators as a variable selection problem and applying Bayesian methods with continuous shrinkage priors on the effects.

Bisulfite-treated RNA non-conversion in a set of samples is analysed as follows : each sample's non-conversion distribution is identified to a Poisson distribution. P-values adjusted for multiple testing are calculated in each sample. Combined non-conversion P-values and standard errors are calculated on the intersection of the set of samples. For further details, see C Legrand, F Tuorto, M Hartmann, R Liebers, D Jakob, M Helm and F Lyko (2017) <doi:10.1101/gr.210666.116>.