Allows the user to categorise a continuous predictor variable in a logistic or a Cox proportional hazards regression setting, by maximising the discriminative ability of the model. I Barrio, I Arostegui, MX Rodriguez-Alvarez, JM Quintana (2015) <doi:10.1177/0962280215601873>. I Barrio, MX Rodriguez-Alvarez, L Meira-Machado, C Esteban, I Arostegui (2017) <https://www.idescat.cat/sort/sort411/41.1.3.barrio-etal.pdf>.

Efficient C++ optimized functions for numerical and symbolic calculus. It includes basic symbolic arithmetic, tensor calculus, Einstein summing convention, fast computation of the Levi-Civita symbol and generalized Kronecker delta, Taylor series expansion, multivariate Hermite polynomials, accurate high-order derivatives, differential operators (Gradient, Jacobian, Hessian, Divergence, Curl, Laplacian) and numerical integration in arbitrary orthogonal coordinate systems: cartesian, polar, spherical, cylindrical, parabolic or user defined by custom scale factors.

Explore calcium (Ca) and phosphate (Pi) homeostasis with two novel Shiny apps, building upon on a previously published mathematical model written in C, to ensure efficient computations. The underlying model is accessible here <https://pubmed.ncbi.nlm.nih.gov/28747359/)>. The first application explores the fundamentals of Ca-Pi homeostasis, while the second provides interactive case studies for in-depth exploration of the topic, thereby seeking to foster student engagement and an integrative understanding of Ca-Pi regulation.

This package provides methods and plotting functions for displaying categorical data on an interactive heatmap using plotly'. Provides functionality for strictly categorical heatmaps, heatmaps illustrating categorized continuous data and annotated heatmaps. Also, there are various options to interact with the x-axis to prevent overlapping axis labels, e.g. via simple sliders or range sliders. Besides the viewer pane, resulting plots can be saved as a standalone HTML file, embedded in R Markdown documents or in a Shiny app.

This package provides functions to perform the following analyses: i) inferring epistasis from RNAi double knockdown data; ii) identifying gene pairs of multiple mutation patterns; iii) assessing association between gene pairs and survival; and iv) calculating the smallworldness of a graph (e.g., a gene interaction network). Data and analyses are described in Wang, X., Fu, A. Q., McNerney, M. and White, K. P. (2014). Widespread genetic epistasis among breast cancer genes. Nature Communications. 5 4828. <doi:10.1038/ncomms5828>.

Cluster analysis is performed using pairwise distance information and a random partition distribution. The method is implemented for two random partition distributions. It draws samples and then obtains and plots clustering estimates. An implementation of a selection algorithm is provided for the mass parameter of the partition distribution. Since pairwise distances are the principal input to this procedure, it is most comparable to the hierarchical and k-medoids clustering methods. The method is Dahl, Andros, Carter (2022+) <doi:10.1002/sam.11602>.

General optimisation and specific tools for the parameter estimation (i.e. calibration) of complex models, including stochastic ones. It implements generic functions that can be used for fitting any type of models, especially those with non-differentiable objective functions, with the same syntax as base::optim. It supports multiple phases estimation (sequential parameter masking), constrained optimization (bounding box restrictions) and automatic parallel computation of numerical gradients. Some common maximum likelihood estimation methods and automated construction of the objective function from simulated model outputs is provided. See <https://roliveros-ramos.github.io/calibrar/> for more details.

The caroline R library contains dozens of functions useful for: database migration (dbWriteTable2), database style joins & aggregation (nerge, groupBy, & bestBy), data structure conversion (nv, tab2df), legend table making (sstable & leghead), automatic legend positioning for scatter and box plots (), plot annotation (labsegs & mvlabs), data visualization (pies, sparge, confound.grid & raPlot), character string manipulation (m & pad), file I/O (write.delim), batch scripting, data exploration, and more. The package's greatest contributions lie in the database style merge, aggregation and interface functions as well as in it's extensive use and propagation of row, column and vector names in most functions.

This package is Cytometry dATa anALYSis Tools (CATALYST). Mass cytometry like Cytometry by time of flight (CyTOF) uses heavy metal isotopes rather than fluorescent tags as reporters to label antibodies, thereby substantially decreasing spectral overlap and allowing for examination of over 50 parameters at the single cell level. While spectral overlap is significantly less pronounced in CyTOF than flow cytometry, spillover due to detection sensitivity, isotopic impurities, and oxide formation can impede data interpretability. CATALYST was designed to provide a pipeline for preprocessing of cytometry data, including:

1. normalization using bead standards;

2. single-cell deconvolution;

3. bead-based compensation.

Intended to analyse recordings from multiple microphones (e.g., backpack microphones in captive setting). It allows users to align recordings even if there is non-linear drift of several minutes between them. A call detection and assignment pipeline can be used to find vocalisations and assign them to the vocalising individuals (even if the vocalisation is picked up on multiple microphones). The tracing and measurement functions allow for detailed analysis of the vocalisations and filtering of noise. Finally, the package includes a function to run spectrographic cross correlation, which can be used to compare vocalisations. It also includes multiple other functions related to analysis of vocal behaviour.

When taking online surveys, participants sometimes respond to items without regard to their content. These types of responses, referred to as careless or insufficient effort responding, constitute significant problems for data quality, leading to distortions in data analysis and hypothesis testing, such as spurious correlations. The R package careless provides solutions designed to detect such careless / insufficient effort responses by allowing easy calculation of indices proposed in the literature. It currently supports the calculation of longstring, even-odd consistency, psychometric synonyms/antonyms, Mahalanobis distance, and intra-individual response variability (also termed inter-item standard deviation). For a review of these methods, see Curran (2016) <doi:10.1016/j.jesp.2015.07.006>.

Fit flexible and fully parametric hazard regression models to survival data with single event type or multiple competing causes via logistic and multinomial regression. Our formulation allows for arbitrary functional forms of time and its interactions with other predictors for time-dependent hazards and hazard ratios. From the fitted hazard model, we provide functions to readily calculate and plot cumulative incidence and survival curves for a given covariate profile. This approach accommodates any log-linear hazard function of prognostic time, treatment, and covariates, and readily allows for non-proportionality. We also provide a plot method for visualizing incidence density via population time plots. Based on the case-base sampling approach of Hanley and Miettinen (2009) <DOI:10.2202/1557-4679.1125>, Saarela and Arjas (2015) <DOI:10.1111/sjos.12125>, and Saarela (2015) <DOI:10.1007/s10985-015-9352-x>.

This package provides the tools to produce catseye plots, principally by catseyesplot() function which calls R's standard plot() function internally, or alternatively by the catseyes() function to overlay the catseye plot onto an existing R plot window. Catseye plots illustrate the normal distribution of the mean (picture a normal bell curve reflected over its base and rotated 90 degrees), with a shaded confidence interval; they are an intuitive way of illustrating and comparing normally distributed estimates, and are arguably a superior alternative to standard confidence intervals, since they show the full distribution rather than fixed quantile bounds. The catseyesplot and catseyes functions require pre-calculated means and standard errors (or standard deviations), provided as numeric vectors; this allows the flexibility of obtaining this information from a variety of sources, such as direct calculation or prediction from a model. Catseye plots, as illustrations of the normal distribution of the means, are described in Cumming (2013 & 2014). Cumming, G. (2013). The new statistics: Why and how. Psychological Science, 27, 7-29. <doi:10.1177/0956797613504966> pmid:24220629.

Assess the calibration of an existing (i.e. previously developed) multistate model through calibration plots. Calibration is assessed using one of three methods. 1) Calibration methods for binary logistic regression models applied at a fixed time point in conjunction with inverse probability of censoring weights. 2) Calibration methods for multinomial logistic regression models applied at a fixed time point in conjunction with inverse probability of censoring weights. 3) Pseudo-values estimated using the Aalen-Johansen estimator of observed risk. All methods are applied in conjunction with landmarking when required. These calibration plots evaluate the calibration (in a validation cohort of interest) of the transition probabilities estimated from an existing multistate model. While package development has focused on multistate models, calibration plots can be produced for any model which utilises information post baseline to update predictions (e.g. dynamic models); competing risks models; or standard single outcome survival models, where predictions can be made at any landmark time. Please see Pate et al. (2024) <doi:10.1002/sim.10094> and Pate et al. (2024) <https://alexpate30.github.io/calibmsm/articles/Overview.html>.

This package implements a class of univariate and multivariate spatial generalised linear mixed models for areal unit data, with inference in a Bayesian setting using Markov chain Monte Carlo (MCMC) simulation using a single or multiple Markov chains. The response variable can be binomial, Gaussian, multinomial, Poisson or zero-inflated Poisson (ZIP), and spatial autocorrelation is modelled by a set of random effects that are assigned a conditional autoregressive (CAR) prior distribution. A number of different models are available for univariate spatial data, including models with no random effects as well as random effects modelled by different types of CAR prior, including the BYM model (Besag et al., 1991, <doi:10.1007/BF00116466>) and Leroux model (Leroux et al., 2000, <doi:10.1007/978-1-4612-1284-3_4>). Additionally, a multivariate CAR (MCAR) model for multivariate spatial data is available, as is a two-level hierarchical model for modelling data relating to individuals within areas. Full details are given in the vignette accompanying this package. The initial creation of this package was supported by the Economic and Social Research Council (ESRC) grant RES-000-22-4256, and on-going development has been supported by the Engineering and Physical Science Research Council (EPSRC) grant EP/J017442/1, ESRC grant ES/K006460/1, Innovate UK / Natural Environment Research Council (NERC) grant NE/N007352/1 and the TB Alliance.

This package enables construction of continuous and non-contiguous area cartograms.

Allows users to identify similar cases for qualitative case studies using statistical matching methods.

This is a package for drawing calibrated scales with tick marks on (non-orthogonal) variable vectors in scatterplots and biplots.

Mainly used to build tables that are commonly presented for bio-medical/health research, such as basic characteristic tables or descriptive statistics.

An implementation of methods for causal discovery in a structural causal model where the conditional distribution of the target node is described by a generalized linear model conditional on its causal parents.

Apply styles to tag elements directly and with the .style pronoun. Using the pronoun, styles are created within the context of a tag element. Change borders, backgrounds, text, margins, layouts, and more.

This package provides functions and data to estimate causal dose response functions given continuous, ordinal, or binary treatments. A description of the methods is given in Galagate (2016) <https://drum.lib.umd.edu/handle/1903/18170>.

Information on activities to promote scholarships in Brazil and abroad for international mobility programs, recorded in Capes computerized payment systems. The CAPES database refers to international mobility programs for the period from 2010 to 2019 <https://dadosabertos.capes.gov.br/dataset/>.

Read and manipulate Camera Trap Data Packages ('Camtrap DP'). Camtrap DP (<https://camtrap-dp.tdwg.org>) is a data exchange format for camera trap data. With camtrapdp you can read, filter and transform data (including to Darwin Core) before further analysis in e.g. camtraptor or camtrapR'.